FI845069A0 - Foerfaranden och mellanprodukter foer framstaellning av 16-fenoxi- och 16-substituerad fenoxi-prostatrienonsyraderivat och deras stereosiomerer. - Google Patents

Foerfaranden och mellanprodukter foer framstaellning av 16-fenoxi- och 16-substituerad fenoxi-prostatrienonsyraderivat och deras stereosiomerer.

Info

Publication number: FI845069A0
Authority: FI; Finland
Prior art keywords: phenoxy; stereosiomerer; prostatrienonsyraderivat; framstaellning; substitutes
Prior art date: 1983-12-22

Application number

FI845069A

Other languages

English (en)

Other versions

FI845069L (fi

FI845069A7 (fi

Inventor

Gary Francis Cooper

Douglas Leslie Wren

Horn Albert Reynolds Van

Tsung-Tee Li

Colin Charles Beard

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-12-22

Filing date

1984-12-20

Publication date

1984-12-20

1984-12-20 Application filed by Syntex Inc filed Critical Syntex Inc

1984-12-20 Priority to FI893303A priority Critical patent/FI893303A0/fi

1984-12-20 Priority to FI893302A priority patent/FI893302A7/fi

1984-12-20 Publication of FI845069A0 publication Critical patent/FI845069A0/fi

1985-06-23 Publication of FI845069L publication Critical patent/FI845069L/fi

1985-06-23 Publication of FI845069A7 publication Critical patent/FI845069A7/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FI845069A 1983-12-22 1984-12-20 Menetelmät ja välituotteet 16-fenoksi- ja 16-substituoidun fenoksi-prostatrienohapon johdannaisten ja niiden stereoisomeerien valmistamiseksi FI845069A7 (fi)

Priority Applications (2)

Application Number	Priority Date	Filing Date	Title
FI893303A FI893303A0 (fi)	1983-12-22	1984-12-20	Foerfarande foer framstaellning av kristallin (4,5,6r,8r)-metyl-9-oxo-11a,15b-dihydroxi-16-fenoxi-17,18,19 ,20-tetranorprosta-4,5,13(e)-trienoat.
FI893302A FI893302A7 (fi)	1983-12-22	1984-12-20	Menetelmiä ja välituotteita 16-fenoksi- ja 16-substituoidun fenoksi-prostatrienonihapon johdannaisten ja niiden stereoisomeerien valmistamiseksi

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/564,386 US4600785A (en)	1983-12-22	1983-12-22	Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives

Publications (3)

Publication Number	Publication Date
FI845069A0 true FI845069A0 (fi)	1984-12-20
FI845069L FI845069L (fi)	1985-06-23
FI845069A7 FI845069A7 (fi)	1985-06-23

Family

ID=24254259

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI845069A FI845069A7 (fi)	1983-12-22	1984-12-20	Menetelmät ja välituotteet 16-fenoksi- ja 16-substituoidun fenoksi-prostatrienohapon johdannaisten ja niiden stereoisomeerien valmistamiseksi

Country Status (28)

Country	Link
US (1)	US4600785A (fi)
EP (1)	EP0146935B1 (fi)
JP (3)	JPH0635431B2 (fi)
KR (1)	KR900000684B1 (fi)
CN (1)	CN85101840A (fi)
AR (1)	AR241015A1 (fi)
AT (1)	ATE50986T1 (fi)
AU (1)	AU585844B2 (fi)
CA (4)	CA1267892A (fi)
CS (5)	CS600784A2 (fi)
DD (2)	DD241254A5 (fi)
DE (1)	DE3481610D1 (fi)
DK (1)	DK617084A (fi)
ES (4)	ES8604389A1 (fi)
FI (1)	FI845069A7 (fi)
GR (1)	GR82514B (fi)
HU (2)	HU197302B (fi)
IL (1)	IL73881A (fi)
IN (1)	IN160437B (fi)
MX (2)	MX158754A (fi)
NO (1)	NO845148L (fi)
NZ (1)	NZ210667A (fi)
PH (2)	PH22893A (fi)
PL (2)	PL255723A1 (fi)
PT (1)	PT79720A (fi)
RO (2)	RO91666B (fi)
SU (3)	SU1473709A3 (fi)
ZA (1)	ZA849967B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4778904A (en) *	1985-09-13	1988-10-18	Syntex (U.S.A.) Inc.	Intermediates for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
NO163485C (no) *	1984-10-09	1990-06-06	Syntex Inc	Mellomprodukter for fremstilling av 16-fenoksy- og 16-substituerte fenoksy-prostatriensyrederivater og fremgangsmaate ved fremstilling av mellomproduktene.
US4929740A (en) *	1984-10-09	1990-05-29	Syntex (U.S.A.) Inc.	Process for making 16-phenoxy- and 16-(substituted phenoxy)-prostatrienoic acid derivatives
US4755531A (en) *	1986-08-11	1988-07-05	Syntex (U.S.A.) Inc.	Thiol esters of 4,5-allenyl prostaglandins and use thereof as antigastric secretion agents
US4689419A (en) *	1986-11-14	1987-08-25	G. D. Searle & Co.	Novel intermediate compounds in a process for producing 16-phenoxy- and 16-substituted phenoxy-9-keto-prostatrienoic acid derivatives
US5248788A (en) *	1988-12-13	1993-09-28	Syntex (U.S.A.) Inc.	Process for preparing allenic prostanoic acid derivatives
US4916238A (en) *	1988-12-13	1990-04-10	Syntex (U.S.A.) Inc.	Process for preparing allenic prostanoic acid derivatives
US5571936A (en) *	1994-09-30	1996-11-05	Korea Institute Of Science And Technology	Intermediates for the synthesis of 16-phenoxy-prostatrienoic acid derivatives and a preparing method thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4304907A (en) *	1972-05-10	1981-12-08	The Upjohn Company	Bicyclo lactone intermediates for prostaglandin analogs
JPS5434724B2 (fi) *	1974-09-19	1979-10-29
GB1590022A (en) *	1976-08-23	1981-05-28	Ono Pharmaceutical Co	Prostaglandin analogues
US4178457A (en) *	1978-07-10	1979-12-11	Syntex (U.S.A.) Inc.	(dl)-16-Phenoxy- and 16-substituted phenoxy-9-keto prostatrienoic acid derivatives and processes for the production thereof
DE3030477C2 (de) *	1980-08-12	1986-10-16	Dr. Willmar Schwabe GmbH & Co, 7500 Karlsruhe	Iridoid-Derivate, Verfahren zu ihrer Herstellung und deren Verwendung
US4389414A (en) *	1981-05-11	1983-06-21	Syntex (U.S.A.) Inc.	Prostaglandin compositions
JPS5931711A (ja) *	1982-07-19	1984-02-20	シンテツクス（ユ−・エス・エイ）インコ−ポレ−テツド	酸単離ゼラチンにより被包したｐｇｅ型組成物
HU196174B (en) *	1984-07-31	1988-10-28	Syntex Inc	Process for preparing new prostaglandin derivatives and pharmaceutical compositions containing such active substance
US4618696A (en) *	1984-07-31	1986-10-21	Syntex (U.S.A.) Inc.	9-oxo-15α-hydroxy-16-phenoxy and 16-substituted phenoxy 17,18,19,20-tetranorprosta-4,5,13,(E)-trienoates
NO163485C (no) *	1984-10-09	1990-06-06	Syntex Inc	Mellomprodukter for fremstilling av 16-fenoksy- og 16-substituerte fenoksy-prostatriensyrederivater og fremgangsmaate ved fremstilling av mellomproduktene.

1983
- 1983-12-22 US US06/564,386 patent/US4600785A/en not_active Expired - Fee Related
1984
- 1984-12-19 GR GR82514A patent/GR82514B/el unknown
- 1984-12-20 PT PT79720A patent/PT79720A/pt unknown
- 1984-12-20 MX MX203853A patent/MX158754A/es unknown
- 1984-12-20 AU AU37120/84A patent/AU585844B2/en not_active Ceased
- 1984-12-20 IN IN1020/MAS/84A patent/IN160437B/en unknown
- 1984-12-20 AT AT84115950T patent/ATE50986T1/de not_active IP Right Cessation
- 1984-12-20 DK DK617084A patent/DK617084A/da not_active Application Discontinuation
- 1984-12-20 CA CA000470699A patent/CA1267892A/en not_active Expired - Fee Related
- 1984-12-20 PH PH31623A patent/PH22893A/en unknown
- 1984-12-20 ZA ZA849967A patent/ZA849967B/xx unknown
- 1984-12-20 DD DD84271309A patent/DD241254A5/de not_active IP Right Cessation
- 1984-12-20 RO RO116780A patent/RO91666B/ro unknown
- 1984-12-20 JP JP59270571A patent/JPH0635431B2/ja not_active Expired - Lifetime
- 1984-12-20 RO RO84124019A patent/RO94561A7/ro unknown
- 1984-12-20 CS CS866007A patent/CS600784A2/cs unknown
- 1984-12-20 CS CS8410132A patent/CS257784B2/cs unknown
- 1984-12-20 PL PL25572384A patent/PL255723A1/xx unknown
- 1984-12-20 EP EP84115950A patent/EP0146935B1/en not_active Expired - Lifetime
- 1984-12-20 HU HU844754A patent/HU197302B/hu not_active IP Right Cessation
- 1984-12-20 PL PL1984251088A patent/PL154330B1/pl unknown
- 1984-12-20 CS CS866008A patent/CS600884A2/cs unknown
- 1984-12-20 NO NO845148A patent/NO845148L/no unknown
- 1984-12-20 IL IL73881A patent/IL73881A/xx unknown
- 1984-12-20 NZ NZ210667A patent/NZ210667A/xx unknown
- 1984-12-20 HU HU863355A patent/HU196732B/hu not_active IP Right Cessation
- 1984-12-20 DE DE8484115950T patent/DE3481610D1/de not_active Expired - Fee Related
- 1984-12-20 DD DD84294680A patent/DD249700A5/de unknown
- 1984-12-20 ES ES538899A patent/ES8604389A1/es not_active Expired
- 1984-12-20 SU SU843828202A patent/SU1473709A3/ru active
- 1984-12-20 KR KR1019840008147A patent/KR900000684B1/ko not_active Expired
- 1984-12-20 AR AR299047A patent/AR241015A1/es active
- 1984-12-20 FI FI845069A patent/FI845069A7/fi not_active Application Discontinuation
1985
- 1985-04-01 CN CN198585101840A patent/CN85101840A/zh active Pending
- 1985-09-24 SU SU853955489A patent/SU1342411A3/ru active
- 1985-09-24 SU SU853955491A patent/SU1356959A3/ru active
- 1985-10-31 ES ES548459A patent/ES8609234A1/es not_active Expired
- 1985-10-31 ES ES548460A patent/ES8607229A1/es not_active Expired
- 1985-10-31 ES ES548453A patent/ES8607228A1/es not_active Expired
1986
- 1986-05-09 PH PH33751A patent/PH23728A/en unknown
- 1986-08-14 CS CS866008A patent/CS257797B2/cs unknown
- 1986-08-14 CS CS866007A patent/CS257796B2/cs unknown
1988
- 1988-08-09 MX MX1259988A patent/MX12599A/es unknown
- 1988-08-11 CA CA000574538A patent/CA1283408C/en not_active Expired - Fee Related
- 1988-08-11 CA CA000574537A patent/CA1276931C/en not_active Expired - Fee Related
- 1988-08-12 CA CA000574703A patent/CA1283409C/en not_active Expired - Fee Related
1991
- 1991-12-19 JP JP3336862A patent/JPH0717597B2/ja not_active Expired - Lifetime
- 1991-12-19 JP JP3336857A patent/JPH0772170B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES8609234A1 (es)	1986-08-01
CS257797B2 (en)	1988-06-15
KR850004589A (ko)	1985-07-25
IL73881A0 (en)	1985-03-31
NO845148L (no)	1985-06-24
CA1283408C (en)	1991-04-23
AU3712084A (en)	1985-07-04
PL251088A1 (en)	1985-12-17
ES8607228A1 (es)	1986-06-01
ATE50986T1 (de)	1990-03-15
JPS60169459A (ja)	1985-09-02
PH22893A (en)	1989-01-19
JPH0539263A (ja)	1993-02-19
ES8604389A1 (es)	1986-02-01
US4600785A (en)	1986-07-15
PT79720A (en)	1985-01-01
ES548460A0 (es)	1986-06-01
ES8607229A1 (es)	1986-06-01
IN160437B (fi)	1987-07-11
ES538899A0 (es)	1986-02-01
DE3481610D1 (de)	1990-04-19
HU197302B (en)	1989-03-28
PH23728A (en)	1989-11-03
JPH0772170B2 (ja)	1995-08-02
DD241254A5 (de)	1986-12-03
NZ210667A (en)	1988-08-30
ES548459A0 (es)	1986-08-01
FI845069L (fi)	1985-06-23
ES548453A0 (es)	1986-06-01
DK617084A (da)	1985-06-23
EP0146935B1 (en)	1990-03-14
PL154330B1 (en)	1991-08-30
CS600884A2 (en)	1987-09-17
RO91666A (ro)	1987-07-30
CS600784A2 (en)	1987-09-17
EP0146935A3 (en)	1987-05-06
EP0146935A2 (en)	1985-07-03
IL73881A (en)	1990-01-18
CS1013284A2 (en)	1987-09-17
DK617084D0 (da)	1984-12-20
KR900000684B1 (ko)	1990-02-03
JPH0635431B2 (ja)	1994-05-11
PL255723A1 (en)	1986-07-29
CS257796B2 (en)	1988-06-15
RO94561A7 (ro)	1988-06-30
CA1267892A (en)	1990-04-17
CA1283409C (en)	1991-04-23
SU1342411A3 (ru)	1987-09-30
CN85101840A (zh)	1987-01-17
CA1276931C (en)	1990-11-27
SU1473709A3 (ru)	1989-04-15
JPH0539262A (ja)	1993-02-19
AR241015A2 (es)	1991-04-30
ZA849967B (en)	1986-08-27
SU1356959A3 (ru)	1987-11-30
MX158754A (es)	1989-03-10
JPH0717597B2 (ja)	1995-03-01
RO91666B (ro)	1987-07-31
GR82514B (en)	1985-04-11
HUT36090A (en)	1985-08-28
FI845069A7 (fi)	1985-06-23
HU196732B (en)	1989-01-30
DD249700A5 (de)	1987-09-16
AU585844B2 (en)	1989-06-29
CS257784B2 (en)	1988-06-15
AR241015A1 (es)	1991-04-30
MX12599A (es)	1993-05-01

Publication	Publication Date	Title
FI840737L (fi)	1984-08-25	Mobil anordning foer foerflyttning av transportabla betongdelar och lyftgods.
FI832684L (fi)	1985-01-26	Foerfarande och ungsanordning foer boejning av glasskivor.
FI840839A7 (fi)	1984-09-15	Imidazoliner och motsvarande foereningar och framstaellning av dem.
FI842945A0 (fi)	1984-07-24	Foerfarande och anordning foer kalanderind av en bana.
ATE21741T1 (de)	1986-09-15	Stopfbuchse.
DE3576138D1 (de)	1990-04-05	Verpackungsmaschine.
FI852010A0 (fi)	1985-05-20	Foerfarande foer framstaellning av herbicidiskt aktiva fenylkarbamater och herbicidiska sammansaettningar innehaollande dem.
FI845069L (fi)	1985-06-23	Foerfaranden och mellanprodukter foer framstaellning av 16-fenoxi- och 16-substituerad fenoxi-prostatrienonsyraderivat och deras stereosiomerer.
FI820994L (fi)	1982-09-24	Foerfarande foer framstaellning av halometylestrar (och beslaektade estrar) av penicillansyra-1,1-dioxid
ES506233A0 (es)	1982-09-01	Disposicion de maquinita de lizos.
FI833234L (fi)	1984-08-19	Krympfilmer av lineaer polyeten och foerfarande foer framstaellning av dem.
FI831802L (fi)	1984-11-21	Stroemningsregulator och anvaendning av denna.
BR8007329A (pt)	1982-06-22	Maquina de embalagem
FI831524L (fi)	1984-11-04	Foerfarande och anordning foer aostadkommande av en av intensitetfoerdelning justerbar elektronridao.
BR8402779A (pt)	1985-05-14	Maquineta
FI832885L (fi)	1985-02-12	Kapasitiv laesmetod foer kodkort och laesanordning foer foerverkligande av foerfarandet.
FI832401L (fi)	1984-12-31	Foerfarande foer framstaellning och belaeggning av skivformiga stycken.
DE3381587D1 (de)	1990-06-28	Verpackungsmaschine.
FI834023A0 (fi)	1983-11-02	Tiofen-2-karboxylsyraderivat och foerfarande foer framstaellning av dem
FI830402L (fi)	1984-09-13	Foerfarande och anordning foer styrning av funktionen av en borrmaskins matningsmotor.
FI831997L (fi)	1984-12-04	Foerfarande och anordning foer katalytisk oxidering av svaveldioxid.
FI844433A0 (fi)	1984-11-12	Foerfarande och apparatur foer analysering av svaveltrioxid.
FI840605L (fi)	1984-08-19	Foerfarande foer moejliggoerande av utbredning och polymerisering av maolarfaerger och ytbelaeggningar under vintern inuti fartygs tankar.
FI831432L (fi)	1984-10-28	Foerfarande och anordning foer behandling och provning av papper.
FI824467L (fi)	1983-06-29	Foerfarande och mellanprodukter foer framstaellning av oktahydrobenzofuro /3,2-e/ isokinoliner

Legal Events

Date	Code	Title	Description
2004-08-31	FD	Application lapsed	Owner name: SYNTEX (U.S.A.) INC.