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TR199902733T2 - Tizoksanit ve nitazoksanitten olusan farmasötik kompozisyonlar. - Google Patents

Tizoksanit ve nitazoksanitten olusan farmasötik kompozisyonlar.

Info

Publication number
TR199902733T2
TR199902733T2 TR1999/02733T TR9902733T TR199902733T2 TR 199902733 T2 TR199902733 T2 TR 199902733T2 TR 1999/02733 T TR1999/02733 T TR 1999/02733T TR 9902733 T TR9902733 T TR 9902733T TR 199902733 T2 TR199902733 T2 TR 199902733T2
Authority
TR
Turkey
Prior art keywords
pharmaceutical compositions
formula
tizoxanide
nitazoxanide
micrometers
Prior art date
Application number
TR1999/02733T
Other languages
English (en)
Inventor
Rossignol Jean-Francois
Original Assignee
Romark Laboratories, L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27420362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR199902733(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/852,447 external-priority patent/US5968961A/en
Priority claimed from US08/887,810 external-priority patent/US5856348A/en
Priority claimed from US08/887,809 external-priority patent/US5965590A/en
Application filed by Romark Laboratories, L.C. filed Critical Romark Laboratories, L.C.
Publication of TR199902733T2 publication Critical patent/TR199902733T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A61P33/12—Schistosomicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Aktif madde olarak formül (I) ve formül (II)' den mütesekkil grup arasindan seçilmis en az bir bilesik ihtiva eden farmasötik bir kompozisyon. Aktif madde tercihen partikül boyutu 200 mikro metre' den küçük ve ortalama partikül boyutu 10 mikrometre' den büyük partiküller seklindedir. Farmasötik kompozisyonlar tercihen farmasötik açidan kabul gören en az bir asit ile dengelenir. Farmasötik kompozisyonlar, taviz veren veya bastirilmis bagisiklik sistemine sahip insanlardaki firsatçi enfeksiyonlarin ve yaprak solucanlarindan kaynaklanan enfeksiyonlarin tedavisinde özellikle faydalidir. Formül ( I ) Formül ( II )
TR1999/02733T 1997-05-07 1998-05-06 Tizoksanit ve nitazoksanitten olusan farmasötik kompozisyonlar. TR199902733T2 (tr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/852,447 US5968961A (en) 1997-05-07 1997-05-07 Pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,810 US5856348A (en) 1994-09-08 1997-07-03 Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,809 US5965590A (en) 1994-09-08 1997-07-03 Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide

Publications (1)

Publication Number Publication Date
TR199902733T2 true TR199902733T2 (tr) 2000-03-21

Family

ID=27420362

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1999/02733T TR199902733T2 (tr) 1997-05-07 1998-05-06 Tizoksanit ve nitazoksanitten olusan farmasötik kompozisyonlar.

Country Status (35)

Country Link
EP (2) EP1005342B1 (tr)
JP (1) JP3739802B2 (tr)
KR (2) KR100426657B1 (tr)
CN (2) CN100515420C (tr)
AP (1) AP1103A (tr)
AR (1) AR057242A2 (tr)
AT (2) ATE228839T1 (tr)
AU (1) AU740022B2 (tr)
BG (2) BG109365A (tr)
BR (1) BR9808722A (tr)
CA (2) CA2418634C (tr)
CZ (2) CZ298269B6 (tr)
DE (2) DE69827417T2 (tr)
DK (2) DK1005342T3 (tr)
EA (2) EA002908B1 (tr)
EE (1) EE04870B1 (tr)
ES (2) ES2150404T3 (tr)
GE (1) GEP20032970B (tr)
HK (1) HK1025907A1 (tr)
HU (1) HU229641B1 (tr)
IL (2) IL132516A (tr)
IS (1) IS2087B (tr)
LV (1) LV12492B (tr)
ME (1) ME00530B (tr)
NO (2) NO313983B1 (tr)
NZ (2) NZ500149A (tr)
OA (1) OA11169A (tr)
PL (1) PL193275B1 (tr)
PT (2) PT1222921E (tr)
RO (1) RO120605B1 (tr)
SI (1) SI20149B (tr)
SK (2) SK283947B6 (tr)
TR (1) TR199902733T2 (tr)
UA (2) UA57079C2 (tr)
WO (1) WO1998050035A1 (tr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2467321A1 (en) 2004-05-14 2005-11-14 Paul J. Santerre Polymeric coupling agents and pharmaceutically-active polymers made therefrom
ZA200806310B (en) 2006-01-09 2009-12-30 Romark Lab Lc Viral hepatitis treatment
KR101697800B1 (ko) * 2009-02-13 2017-01-18 로마크 레버러토리즈, 엘.씨. 니타족사니드의 서방성 제약 제형
WO2010132404A1 (en) 2009-05-12 2010-11-18 Romark Laboratories L.C. Haloalkyl heteroaryl benzamide compounds
CA2766642C (en) 2009-06-26 2017-09-05 Romark Laboratories L.C. Compounds and methods for treating influenza
MX340846B (es) 2012-01-27 2016-07-28 Rhein Siegfried Sa De Cv Composición de nitazoxanida mejorada y proceso para prepararla.
EP3217795A4 (en) * 2014-11-11 2018-08-22 Romark Laboratories, L.C. Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof
US11612567B2 (en) 2018-02-02 2023-03-28 Ripple Therapeutics Corporation Ocular inserts comprising a covalently linked steroid dimer
CA3176134A1 (en) 2020-05-01 2021-11-04 Ripple Therapeutics Corporation Heterodimer compositions and methods for the treatment of ocular disorders
WO2022130406A1 (en) * 2020-12-15 2022-06-23 Cipla Limited Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1437800A (en) * 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) * 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
US5578621A (en) * 1994-09-08 1996-11-26 Romark Lab Lc Benzamide derivatives
US5387598A (en) * 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen

Also Published As

Publication number Publication date
ME00530B (me) 2011-10-10
DK1222921T3 (da) 2005-03-07
DE69809928T2 (de) 2003-04-24
AR057242A2 (es) 2007-11-21
ES2150404T3 (es) 2003-07-01
ES2232687T3 (es) 2005-06-01
DK1005342T3 (da) 2003-03-24
SK151199A3 (en) 2000-07-11
PT1005342E (pt) 2003-02-28
IL155799A (en) 2004-08-31
SK283946B6 (sk) 2004-05-04
EP1005342A1 (en) 2000-06-07
JP2001503067A (ja) 2001-03-06
LV12492A (en) 2000-06-20
NO995406L (no) 2000-01-04
SI20149B (en) 2001-08-31
NO313983B1 (no) 2003-01-13
CA2418634C (en) 2004-10-26
CZ298269B6 (cs) 2007-08-08
SK283947B6 (sk) 2004-05-04
EP1222921B1 (en) 2004-11-03
CA2288003C (en) 2003-10-21
EP1005342A4 (en) 2001-02-07
CZ298270B6 (cs) 2007-08-08
BG64973B1 (bg) 2006-11-30
DE69827417T2 (de) 2005-10-27
CZ391199A3 (cs) 2000-07-12
PL193275B1 (pl) 2007-01-31
NO995406D0 (no) 1999-11-04
KR20040004544A (ko) 2004-01-13
KR20010020322A (ko) 2001-03-15
EA199901012A1 (ru) 2000-08-28
ES2150404T1 (es) 2000-12-01
LV12492B (en) 2001-01-20
HU229641B1 (en) 2014-03-28
CN1552322A (zh) 2004-12-08
SI20149A (sl) 2000-08-31
KR100426657B1 (ko) 2004-04-13
EE9900578A (et) 2000-08-15
WO1998050035A1 (en) 1998-11-12
OA11169A (en) 2003-04-25
BR9808722A (pt) 2000-07-11
AU740022B2 (en) 2001-10-25
PL336805A1 (en) 2000-07-17
IL132516A (en) 2003-12-10
IS5223A (is) 1999-10-19
DE69827417D1 (de) 2004-12-09
HK1025907A1 (en) 2000-12-01
EA002908B1 (ru) 2002-10-31
ATE228839T1 (de) 2002-12-15
CA2288003A1 (en) 1998-11-12
ATE281166T1 (de) 2004-11-15
AU7289598A (en) 1998-11-27
HUP0003330A2 (hu) 2001-05-28
KR100576646B1 (ko) 2006-05-08
AP9901675A0 (en) 1999-12-31
EA002920B1 (ru) 2002-10-31
HUP0003330A3 (en) 2002-10-28
EP1222921A1 (en) 2002-07-17
IL132516A0 (en) 2001-03-19
IL155799A0 (en) 2003-12-23
UA57079C2 (uk) 2003-06-16
BG109365A (en) 2006-08-31
DE69809928D1 (de) 2003-01-16
CN100515420C (zh) 2009-07-22
PT1222921E (pt) 2005-02-28
EA200100956A1 (ru) 2002-02-28
NO20021832L (no) 2000-01-04
NO335781B1 (no) 2015-02-16
AP1103A (en) 2002-09-04
CA2418634A1 (en) 1998-11-12
EP1005342B1 (en) 2002-12-04
EE04870B1 (et) 2007-08-15
GEP20032970B (en) 2003-05-27
CN1158074C (zh) 2004-07-21
NZ513881A (en) 2002-10-25
CN1255060A (zh) 2000-05-31
NZ500149A (en) 2001-11-30
RO120605B1 (ro) 2006-05-30
JP3739802B2 (ja) 2006-01-25
BG103958A (en) 2000-07-31
NO20021832D0 (no) 2002-04-18
UA74388C2 (uk) 2005-12-15
IS2087B (is) 2006-03-15

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