IL132516A - Pharmaceutical compositions of tizoxanide and nitazoxanide - Google Patents

Pharmaceutical compositions of tizoxanide and nitazoxanide

Info

Publication number: IL132516A
Authority: IL; Israel
Prior art keywords: tizoxanide; nitazoxanide; pharmaceutical compositions; pharmaceutical; compositions
Prior art date: 1997-05-07

Application number

IL13251698A

Other languages

English (en)

Other versions

IL132516A0 (en

Original Assignee

Romark Lab Lc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-07

Filing date

1998-05-06

Publication date

2003-12-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27420362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL132516(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-05-07 Priority claimed from US08/852,447 external-priority patent/US5968961A/en

1997-07-03 Priority claimed from US08/887,809 external-priority patent/US5965590A/en

1997-07-03 Priority claimed from US08/887,810 external-priority patent/US5856348A/en

1998-05-06 Application filed by Romark Lab Lc filed Critical Romark Lab Lc

1998-05-06 Priority to IL15579998A priority Critical patent/IL155799A/en

2001-03-19 Publication of IL132516A0 publication Critical patent/IL132516A0/xx

2003-12-10 Publication of IL132516A publication Critical patent/IL132516A/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Medicinal Preparation (AREA)

IL13251698A 1997-05-07 1998-05-06 Pharmaceutical compositions of tizoxanide and nitazoxanide IL132516A (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
IL15579998A IL155799A (en)	1997-05-07	1998-05-06	Pharmaceutical preparations of thizoxanide and nitazoxanide

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US08/852,447 US5968961A (en)	1997-05-07	1997-05-07	Pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,809 US5965590A (en)	1994-09-08	1997-07-03	Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,810 US5856348A (en)	1994-09-08	1997-07-03	Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
PCT/US1998/009229 WO1998050035A1 (en)	1997-05-07	1998-05-06	Pharmaceutical compositions of tizoxanide and nitazoxanide

Publications (2)

Publication Number	Publication Date
IL132516A0 IL132516A0 (en)	2001-03-19
IL132516A true IL132516A (en)	2003-12-10

Family

ID=27420362

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL13251698A IL132516A (en)	1997-05-07	1998-05-06	Pharmaceutical compositions of tizoxanide and nitazoxanide
IL15579998A IL155799A (en)	1997-05-07	1998-05-06	Pharmaceutical preparations of thizoxanide and nitazoxanide

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL15579998A IL155799A (en)	1997-05-07	1998-05-06	Pharmaceutical preparations of thizoxanide and nitazoxanide

Country Status (35)

Country	Link
EP (2)	EP1222921B1 (xx)
JP (1)	JP3739802B2 (xx)
KR (2)	KR100576646B1 (xx)
CN (2)	CN100515420C (xx)
AP (1)	AP1103A (xx)
AR (1)	AR057242A2 (xx)
AT (2)	ATE228839T1 (xx)
AU (1)	AU740022B2 (xx)
BG (2)	BG109365A (xx)
BR (1)	BR9808722A (xx)
CA (2)	CA2288003C (xx)
CZ (2)	CZ298270B6 (xx)
DE (2)	DE69827417T2 (xx)
DK (2)	DK1005342T3 (xx)
EA (2)	EA002920B1 (xx)
EE (1)	EE04870B1 (xx)
ES (2)	ES2150404T3 (xx)
GE (1)	GEP20032970B (xx)
HK (1)	HK1025907A1 (xx)
HU (1)	HU229641B1 (xx)
IL (2)	IL132516A (xx)
IS (1)	IS2087B (xx)
LV (1)	LV12492B (xx)
ME (1)	ME00530B (xx)
NO (2)	NO313983B1 (xx)
NZ (2)	NZ513881A (xx)
OA (1)	OA11169A (xx)
PL (1)	PL193275B1 (xx)
PT (2)	PT1005342E (xx)
RO (1)	RO120605B1 (xx)
SI (1)	SI20149B (xx)
SK (2)	SK283947B6 (xx)
TR (1)	TR199902733T2 (xx)
UA (2)	UA57079C2 (xx)
WO (1)	WO1998050035A1 (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2467321A1 (en)	2004-05-14	2005-11-14	Paul J. Santerre	Polymeric coupling agents and pharmaceutically-active polymers made therefrom
CN101448497B (zh)	2006-01-09	2013-07-10	罗马克实验室有限公司	包含硝唑尼特、替唑尼特、或其混合物的组合物在制备治疗丙型肝炎药物中的应用
EP2395840B1 (en) *	2009-02-13	2020-04-15	Romark Laboratories, L.C.	Controlled release pharmaceutical formulations of nitazoxanide
AU2010247816B2 (en)	2009-05-12	2015-12-17	Romark Laboratories L.C.	Haloalkyl heteroaryl benzamide compounds
AP2012006064A0 (en)	2009-06-26	2012-02-29	Romark Lab Lc	Compounds and methods for treating influenza.
WO2013110975A1 (es)	2012-01-27	2013-08-01	Siegfried Rhein S.A. De C.V.	Composición de nitazoxanida mejorada y proceso para prepararla
EP3217795A4 (en) *	2014-11-11	2018-08-22	Romark Laboratories, L.C.	Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof
JP7502186B2 (ja)	2018-02-02	2024-06-18	リップルセラピューティクスコーポレーション	ステロイド二量体を含むガラス製剤およびその使用
CN115956083A (zh)	2020-05-01	2023-04-11	波纹疗法公司	异二聚体组合物及用于治疗眼部病症的方法
WO2022130406A1 (en) *	2020-12-15	2022-06-23	Cipla Limited	Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1437800A (en) *	1973-08-08	1976-06-03	Phavic Sprl	Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) *	1978-12-07	1982-02-09	Rossignol Jean F	Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
US5578621A (en) *	1994-09-08	1996-11-26	Romark Lab Lc	Benzamide derivatives
US5387598A (en) *	1994-04-13	1995-02-07	Rossignol; Jean-Francois	Composition and galenic formulation suitable for combatting affections of the lower abdomen

1998
- 1998-05-06 JP JP54843798A patent/JP3739802B2/ja not_active Expired - Fee Related
- 1998-05-06 EA EA200100956A patent/EA002920B1/ru not_active IP Right Cessation
- 1998-05-06 WO PCT/US1998/009229 patent/WO1998050035A1/en active IP Right Grant
- 1998-05-06 CZ CZ20060366A patent/CZ298270B6/cs not_active IP Right Cessation
- 1998-05-06 PT PT98920285T patent/PT1005342E/pt unknown
- 1998-05-06 PT PT02002887T patent/PT1222921E/pt unknown
- 1998-05-06 SK SK708-2003A patent/SK283947B6/sk unknown
- 1998-05-06 ES ES98920285T patent/ES2150404T3/es not_active Expired - Lifetime
- 1998-05-06 CZ CZ0391199A patent/CZ298269B6/cs not_active IP Right Cessation
- 1998-05-06 EP EP02002887A patent/EP1222921B1/en not_active Expired - Lifetime
- 1998-05-06 IL IL13251698A patent/IL132516A/xx not_active IP Right Cessation
- 1998-05-06 AT AT98920285T patent/ATE228839T1/de active
- 1998-05-06 DK DK98920285T patent/DK1005342T3/da active
- 1998-05-06 EP EP98920285A patent/EP1005342B1/en not_active Expired - Lifetime
- 1998-05-06 CA CA002288003A patent/CA2288003C/en not_active Expired - Fee Related
- 1998-05-06 SI SI9820037A patent/SI20149B/sl not_active IP Right Cessation
- 1998-05-06 HU HU0003330A patent/HU229641B1/hu not_active IP Right Cessation
- 1998-05-06 NZ NZ513881A patent/NZ513881A/xx not_active IP Right Cessation
- 1998-05-06 SK SK1511-99A patent/SK283946B6/sk unknown
- 1998-05-06 RO RO99-01166A patent/RO120605B1/ro unknown
- 1998-05-06 KR KR1020037011334A patent/KR100576646B1/ko not_active IP Right Cessation
- 1998-05-06 ES ES02002887T patent/ES2232687T3/es not_active Expired - Lifetime
- 1998-05-06 DE DE69827417T patent/DE69827417T2/de not_active Expired - Lifetime
- 1998-05-06 AU AU72895/98A patent/AU740022B2/en not_active Ceased
- 1998-05-06 EA EA199901012A patent/EA002908B1/ru not_active IP Right Cessation
- 1998-05-06 AT AT02002887T patent/ATE281166T1/de active
- 1998-05-06 PL PL336805A patent/PL193275B1/pl not_active IP Right Cessation
- 1998-05-06 GE GEAP19985109A patent/GEP20032970B/en unknown
- 1998-05-06 CN CNB2004100459536A patent/CN100515420C/zh not_active Expired - Fee Related
- 1998-05-06 IL IL15579998A patent/IL155799A/en not_active IP Right Cessation
- 1998-05-06 TR TR1999/02733T patent/TR199902733T2/xx unknown
- 1998-05-06 ME MEP-2008-877A patent/ME00530B/me unknown
- 1998-05-06 DE DE69809928T patent/DE69809928T2/de not_active Expired - Lifetime
- 1998-05-06 BR BR9808722-3A patent/BR9808722A/pt not_active IP Right Cessation
- 1998-05-06 KR KR10-1999-7009930A patent/KR100426657B1/ko not_active IP Right Cessation
- 1998-05-06 DK DK02002887T patent/DK1222921T3/da active
- 1998-05-06 EE EEP199900578A patent/EE04870B1/xx unknown
- 1998-05-06 CA CA002418634A patent/CA2418634C/en not_active Expired - Fee Related
- 1998-05-06 NZ NZ500149A patent/NZ500149A/en not_active IP Right Cessation
- 1998-05-06 AP APAP/P/1999/001675A patent/AP1103A/en active
- 1998-05-06 CN CNB988049007A patent/CN1158074C/zh not_active Expired - Fee Related
- 1998-06-05 UA UA99126626A patent/UA57079C2/uk unknown
- 1998-12-06 BG BG109365A patent/BG109365A/en unknown
1999
- 1999-10-19 IS IS5223A patent/IS2087B/is unknown
- 1999-10-29 OA OA9900239A patent/OA11169A/en unknown
- 1999-11-04 NO NO19995406A patent/NO313983B1/no not_active IP Right Cessation
- 1999-12-01 LV LVP-99-170A patent/LV12492B/en unknown
- 1999-12-06 BG BG103958A patent/BG64973B1/bg unknown
2000
- 2000-08-17 HK HK00105181A patent/HK1025907A1/xx not_active IP Right Cessation
2002
- 2002-04-18 NO NO20021832A patent/NO335781B1/no not_active IP Right Cessation
2003
- 2003-04-04 UA UA2003042974A patent/UA74388C2/uk unknown
2006
- 2006-12-14 AR ARP060105534A patent/AR057242A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP0003330A2 (hu)	2001-05-28
NO20021832D0 (no)	2002-04-18
AU7289598A (en)	1998-11-27
CN1158074C (zh)	2004-07-21
IS5223A (is)	1999-10-19
IL155799A0 (en)	2003-12-23
CA2288003C (en)	2003-10-21
CZ298270B6 (cs)	2007-08-08
NZ500149A (en)	2001-11-30
EA200100956A1 (ru)	2002-02-28
NZ513881A (en)	2002-10-25
EA199901012A1 (ru)	2000-08-28
KR100576646B1 (ko)	2006-05-08
JP3739802B2 (ja)	2006-01-25
BR9808722A (pt)	2000-07-11
SK151199A3 (en)	2000-07-11
CZ298269B6 (cs)	2007-08-08
OA11169A (en)	2003-04-25
EP1222921A1 (en)	2002-07-17
JP2001503067A (ja)	2001-03-06
EP1005342A1 (en)	2000-06-07
IL155799A (en)	2004-08-31
ATE228839T1 (de)	2002-12-15
IL132516A0 (en)	2001-03-19
LV12492A (en)	2000-06-20
RO120605B1 (ro)	2006-05-30
TR199902733T2 (xx)	2000-03-21
ES2232687T3 (es)	2005-06-01
DE69827417T2 (de)	2005-10-27
ATE281166T1 (de)	2004-11-15
EE9900578A (et)	2000-08-15
ES2150404T1 (es)	2000-12-01
AP1103A (en)	2002-09-04
DK1222921T3 (da)	2005-03-07
CN1552322A (zh)	2004-12-08
KR100426657B1 (ko)	2004-04-13
ES2150404T3 (es)	2003-07-01
EP1005342B1 (en)	2002-12-04
BG103958A (en)	2000-07-31
NO995406D0 (no)	1999-11-04
CA2418634A1 (en)	1998-11-12
NO20021832L (no)	2000-01-04
HK1025907A1 (en)	2000-12-01
PT1005342E (pt)	2003-02-28
CN1255060A (zh)	2000-05-31
SK283947B6 (sk)	2004-05-04
EP1005342A4 (en)	2001-02-07
NO995406L (no)	2000-01-04
IS2087B (is)	2006-03-15
LV12492B (en)	2001-01-20
PL193275B1 (pl)	2007-01-31
SI20149A (sl)	2000-08-31
HU229641B1 (en)	2014-03-28
DE69827417D1 (de)	2004-12-09
HUP0003330A3 (en)	2002-10-28
CA2288003A1 (en)	1998-11-12
GEP20032970B (en)	2003-05-27
SK283946B6 (sk)	2004-05-04
EA002920B1 (ru)	2002-10-31
DE69809928D1 (de)	2003-01-16
KR20010020322A (ko)	2001-03-15
PT1222921E (pt)	2005-02-28
NO335781B1 (no)	2015-02-16
EP1222921B1 (en)	2004-11-03
AU740022B2 (en)	2001-10-25
BG64973B1 (bg)	2006-11-30
AP9901675A0 (en)	1999-12-31
CA2418634C (en)	2004-10-26
SI20149B (en)	2001-08-31
BG109365A (en)	2006-08-31
DE69809928T2 (de)	2003-04-24
UA57079C2 (uk)	2003-06-16
NO313983B1 (no)	2003-01-13
PL336805A1 (en)	2000-07-17
KR20040004544A (ko)	2004-01-13
EA002908B1 (ru)	2002-10-31
UA74388C2 (uk)	2005-12-15
WO1998050035A1 (en)	1998-11-12
EE04870B1 (et)	2007-08-15
AR057242A2 (es)	2007-11-21
CZ391199A3 (cs)	2000-07-12
DK1005342T3 (da)	2003-03-24
ME00530B (me)	2011-10-10
CN100515420C (zh)	2009-07-22

Publication	Publication Date	Title
HUP0101999A3 (en)	2003-06-30	4-hydroxyquinoline-3-carboxamides and hydrazides use of them and pharmaceutical compositions containing them
IL135589A0 (en)	2001-05-20	Aminothiazole derivatives and pharmaceutical compositions containing the same
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HUP0103874A3 (en)	2002-09-30	Use of antibiotics and pharmaceutical compositions comprising thereof
HUP0001309A3 (en)	2000-12-28	1-phenyl-4-benzylpiperazines and pharmaceutical compositions containing them
LT99141A (en)	2000-08-25	Pharmaceutical compositions of tizoxanide and nitazoxanide
IL135646A0 (en)	2001-05-20	α-ARYL-N-ALKYLNITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
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HUP0000460A3 (en)	2001-04-28	Imidazopyridazines and pharmaceutical compositions thereof
AU7681498A (en)	1998-12-11	Pharmaceutical composition and use thereof
HUP9900251A3 (en)	2001-01-29	Pharmaceutical compositions containing hedgehog proteins and use of former compositions
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HUP0003827A3 (en)	2001-09-28	Cyanoamidine derivatives and pharmaceutical compositions containing them
GB9721071D0 (en)	1997-12-03	Pharmaceutical compositions and their use
HU9702369D0 (en)	1998-03-02	Pharmaceutical composition of natural active components
HUP9903370A3 (en)	2001-03-28	Beta-sulfonamido hydroxamic acids and pharmaceutical compositions containing them

Legal Events

Date	Code	Title
2004-05-12	FF	Patent granted
2004-07-25	KB	Patent renewed
2008-07-09	KB	Patent renewed
2012-12-31	MM9K	Patent not in force due to non-payment of renewal fees