HUP0003330A2 - Tizoxanidot és nitazoxanidot tartalmazó gyógyszerkészítmények - Google Patents
Tizoxanidot és nitazoxanidot tartalmazó gyógyszerkészítményekInfo
- Publication number
- HUP0003330A2 HUP0003330A2 HU0003330A HUP0003330A HUP0003330A2 HU P0003330 A2 HUP0003330 A2 HU P0003330A2 HU 0003330 A HU0003330 A HU 0003330A HU P0003330 A HUP0003330 A HU P0003330A HU P0003330 A2 HUP0003330 A2 HU P0003330A2
- Authority
- HU
- Hungary
- Prior art keywords
- tizoxanide
- nitazoxanide
- pharmaceutical compositions
- compositions containing
- compound
- Prior art date
Links
- FDTZUTSGGSRHQF-UHFFFAOYSA-N Desacetyl-nitazoxanide Chemical compound OC1=CC=CC=C1C(=O)NC1=NC=C([N+]([O-])=O)S1 FDTZUTSGGSRHQF-UHFFFAOYSA-N 0.000 title 1
- YQNQNVDNTFHQSW-UHFFFAOYSA-N acetic acid [2-[[(5-nitro-2-thiazolyl)amino]-oxomethyl]phenyl] ester Chemical compound CC(=O)OC1=CC=CC=C1C(=O)NC1=NC=C([N+]([O-])=O)S1 YQNQNVDNTFHQSW-UHFFFAOYSA-N 0.000 title 1
- 229960002480 nitazoxanide Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 3
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
- A61P33/12—Schistosomicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
Abstract
A találmány tárgya olyan gyógyszerkészítmény, amely hatóanyagként az(I) képletű és a (II) képletű vegyület által alkotott csoportból kiválasztottlegalább egy vegyület tartalmaz. A hatóanyag előnyösen részecskékformájában van jelen, amelyeknek részecskemérete kisebb, mint 200 m ésaz átlagos részecskeméret nagyobb, mint 10 m, és a készítmény legalábbegy gyógyszerészetileg elfogadható savat is tartalmazhat. Ó
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/852,447 US5968961A (en) | 1997-05-07 | 1997-05-07 | Pharmaceutical compositions of tizoxanide and nitazoxanide |
US08/887,809 US5965590A (en) | 1994-09-08 | 1997-07-03 | Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide |
US08/887,810 US5856348A (en) | 1994-09-08 | 1997-07-03 | Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide |
PCT/US1998/009229 WO1998050035A1 (en) | 1997-05-07 | 1998-05-06 | Pharmaceutical compositions of tizoxanide and nitazoxanide |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0003330A2 true HUP0003330A2 (hu) | 2001-05-28 |
HUP0003330A3 HUP0003330A3 (en) | 2002-10-28 |
HU229641B1 HU229641B1 (en) | 2014-03-28 |
Family
ID=27420362
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0003330A HU229641B1 (en) | 1997-05-07 | 1998-05-06 | Pharmaceutical compositions containing tizoxanide and nitazoxanide |
Country Status (35)
Country | Link |
---|---|
EP (2) | EP1222921B1 (hu) |
JP (1) | JP3739802B2 (hu) |
KR (2) | KR100576646B1 (hu) |
CN (2) | CN100515420C (hu) |
AP (1) | AP1103A (hu) |
AR (1) | AR057242A2 (hu) |
AT (2) | ATE228839T1 (hu) |
AU (1) | AU740022B2 (hu) |
BG (2) | BG109365A (hu) |
BR (1) | BR9808722A (hu) |
CA (2) | CA2288003C (hu) |
CZ (2) | CZ298270B6 (hu) |
DE (2) | DE69827417T2 (hu) |
DK (2) | DK1005342T3 (hu) |
EA (2) | EA002920B1 (hu) |
EE (1) | EE04870B1 (hu) |
ES (2) | ES2150404T3 (hu) |
GE (1) | GEP20032970B (hu) |
HK (1) | HK1025907A1 (hu) |
HU (1) | HU229641B1 (hu) |
IL (2) | IL132516A (hu) |
IS (1) | IS2087B (hu) |
LV (1) | LV12492B (hu) |
ME (1) | ME00530B (hu) |
NO (2) | NO313983B1 (hu) |
NZ (2) | NZ513881A (hu) |
OA (1) | OA11169A (hu) |
PL (1) | PL193275B1 (hu) |
PT (2) | PT1005342E (hu) |
RO (1) | RO120605B1 (hu) |
SI (1) | SI20149B (hu) |
SK (2) | SK283947B6 (hu) |
TR (1) | TR199902733T2 (hu) |
UA (2) | UA57079C2 (hu) |
WO (1) | WO1998050035A1 (hu) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2467321A1 (en) | 2004-05-14 | 2005-11-14 | Paul J. Santerre | Polymeric coupling agents and pharmaceutically-active polymers made therefrom |
CN101448497B (zh) | 2006-01-09 | 2013-07-10 | 罗马克实验室有限公司 | 包含硝唑尼特、替唑尼特、或其混合物的组合物在制备治疗丙型肝炎药物中的应用 |
EP2395840B1 (en) * | 2009-02-13 | 2020-04-15 | Romark Laboratories, L.C. | Controlled release pharmaceutical formulations of nitazoxanide |
AU2010247816B2 (en) | 2009-05-12 | 2015-12-17 | Romark Laboratories L.C. | Haloalkyl heteroaryl benzamide compounds |
AP2012006064A0 (en) | 2009-06-26 | 2012-02-29 | Romark Lab Lc | Compounds and methods for treating influenza. |
WO2013110975A1 (es) | 2012-01-27 | 2013-08-01 | Siegfried Rhein S.A. De C.V. | Composición de nitazoxanida mejorada y proceso para prepararla |
EP3217795A4 (en) * | 2014-11-11 | 2018-08-22 | Romark Laboratories, L.C. | Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof |
JP7502186B2 (ja) | 2018-02-02 | 2024-06-18 | リップル セラピューティクス コーポレーション | ステロイド二量体を含むガラス製剤およびその使用 |
CN115956083A (zh) | 2020-05-01 | 2023-04-11 | 波纹疗法公司 | 异二聚体组合物及用于治疗眼部病症的方法 |
WO2022130406A1 (en) * | 2020-12-15 | 2022-06-23 | Cipla Limited | Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1437800A (en) * | 1973-08-08 | 1976-06-03 | Phavic Sprl | Derivatives of 2-benzamido-5-nitro-thiazoles |
US4315018A (en) * | 1978-12-07 | 1982-02-09 | Rossignol Jean F | Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives |
US5578621A (en) * | 1994-09-08 | 1996-11-26 | Romark Lab Lc | Benzamide derivatives |
US5387598A (en) * | 1994-04-13 | 1995-02-07 | Rossignol; Jean-Francois | Composition and galenic formulation suitable for combatting affections of the lower abdomen |
-
1998
- 1998-05-06 JP JP54843798A patent/JP3739802B2/ja not_active Expired - Fee Related
- 1998-05-06 EA EA200100956A patent/EA002920B1/ru not_active IP Right Cessation
- 1998-05-06 WO PCT/US1998/009229 patent/WO1998050035A1/en active IP Right Grant
- 1998-05-06 CZ CZ20060366A patent/CZ298270B6/cs not_active IP Right Cessation
- 1998-05-06 PT PT98920285T patent/PT1005342E/pt unknown
- 1998-05-06 PT PT02002887T patent/PT1222921E/pt unknown
- 1998-05-06 SK SK708-2003A patent/SK283947B6/sk unknown
- 1998-05-06 ES ES98920285T patent/ES2150404T3/es not_active Expired - Lifetime
- 1998-05-06 CZ CZ0391199A patent/CZ298269B6/cs not_active IP Right Cessation
- 1998-05-06 EP EP02002887A patent/EP1222921B1/en not_active Expired - Lifetime
- 1998-05-06 IL IL13251698A patent/IL132516A/xx not_active IP Right Cessation
- 1998-05-06 AT AT98920285T patent/ATE228839T1/de active
- 1998-05-06 DK DK98920285T patent/DK1005342T3/da active
- 1998-05-06 EP EP98920285A patent/EP1005342B1/en not_active Expired - Lifetime
- 1998-05-06 CA CA002288003A patent/CA2288003C/en not_active Expired - Fee Related
- 1998-05-06 SI SI9820037A patent/SI20149B/sl not_active IP Right Cessation
- 1998-05-06 HU HU0003330A patent/HU229641B1/hu not_active IP Right Cessation
- 1998-05-06 NZ NZ513881A patent/NZ513881A/xx not_active IP Right Cessation
- 1998-05-06 SK SK1511-99A patent/SK283946B6/sk unknown
- 1998-05-06 RO RO99-01166A patent/RO120605B1/ro unknown
- 1998-05-06 KR KR1020037011334A patent/KR100576646B1/ko not_active IP Right Cessation
- 1998-05-06 ES ES02002887T patent/ES2232687T3/es not_active Expired - Lifetime
- 1998-05-06 DE DE69827417T patent/DE69827417T2/de not_active Expired - Lifetime
- 1998-05-06 AU AU72895/98A patent/AU740022B2/en not_active Ceased
- 1998-05-06 EA EA199901012A patent/EA002908B1/ru not_active IP Right Cessation
- 1998-05-06 AT AT02002887T patent/ATE281166T1/de active
- 1998-05-06 PL PL336805A patent/PL193275B1/pl not_active IP Right Cessation
- 1998-05-06 GE GEAP19985109A patent/GEP20032970B/en unknown
- 1998-05-06 CN CNB2004100459536A patent/CN100515420C/zh not_active Expired - Fee Related
- 1998-05-06 IL IL15579998A patent/IL155799A/en not_active IP Right Cessation
- 1998-05-06 TR TR1999/02733T patent/TR199902733T2/xx unknown
- 1998-05-06 ME MEP-2008-877A patent/ME00530B/me unknown
- 1998-05-06 DE DE69809928T patent/DE69809928T2/de not_active Expired - Lifetime
- 1998-05-06 BR BR9808722-3A patent/BR9808722A/pt not_active IP Right Cessation
- 1998-05-06 KR KR10-1999-7009930A patent/KR100426657B1/ko not_active IP Right Cessation
- 1998-05-06 DK DK02002887T patent/DK1222921T3/da active
- 1998-05-06 EE EEP199900578A patent/EE04870B1/xx unknown
- 1998-05-06 CA CA002418634A patent/CA2418634C/en not_active Expired - Fee Related
- 1998-05-06 NZ NZ500149A patent/NZ500149A/en not_active IP Right Cessation
- 1998-05-06 AP APAP/P/1999/001675A patent/AP1103A/en active
- 1998-05-06 CN CNB988049007A patent/CN1158074C/zh not_active Expired - Fee Related
- 1998-06-05 UA UA99126626A patent/UA57079C2/uk unknown
- 1998-12-06 BG BG109365A patent/BG109365A/en unknown
-
1999
- 1999-10-19 IS IS5223A patent/IS2087B/is unknown
- 1999-10-29 OA OA9900239A patent/OA11169A/en unknown
- 1999-11-04 NO NO19995406A patent/NO313983B1/no not_active IP Right Cessation
- 1999-12-01 LV LVP-99-170A patent/LV12492B/en unknown
- 1999-12-06 BG BG103958A patent/BG64973B1/bg unknown
-
2000
- 2000-08-17 HK HK00105181A patent/HK1025907A1/xx not_active IP Right Cessation
-
2002
- 2002-04-18 NO NO20021832A patent/NO335781B1/no not_active IP Right Cessation
-
2003
- 2003-04-04 UA UA2003042974A patent/UA74388C2/uk unknown
-
2006
- 2006-12-14 AR ARP060105534A patent/AR057242A2/es not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of definitive patent protection due to non-payment of fees |