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HUP0003330A2 - Tizoxanidot és nitazoxanidot tartalmazó gyógyszerkészítmények - Google Patents

Tizoxanidot és nitazoxanidot tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0003330A2
HUP0003330A2 HU0003330A HUP0003330A HUP0003330A2 HU P0003330 A2 HUP0003330 A2 HU P0003330A2 HU 0003330 A HU0003330 A HU 0003330A HU P0003330 A HUP0003330 A HU P0003330A HU P0003330 A2 HUP0003330 A2 HU P0003330A2
Authority
HU
Hungary
Prior art keywords
tizoxanide
nitazoxanide
pharmaceutical compositions
compositions containing
compound
Prior art date
Application number
HU0003330A
Other languages
English (en)
Inventor
Jean-Francois Rossignol
Original Assignee
Romark Laboratories, L.C.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27420362&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0003330(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/852,447 external-priority patent/US5968961A/en
Priority claimed from US08/887,809 external-priority patent/US5965590A/en
Priority claimed from US08/887,810 external-priority patent/US5856348A/en
Application filed by Romark Laboratories, L.C. filed Critical Romark Laboratories, L.C.
Publication of HUP0003330A2 publication Critical patent/HUP0003330A2/hu
Publication of HUP0003330A3 publication Critical patent/HUP0003330A3/hu
Publication of HU229641B1 publication Critical patent/HU229641B1/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • A61P33/12Schistosomicides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)

Abstract

A találmány tárgya olyan gyógyszerkészítmény, amely hatóanyagként az(I) képletű és a (II) képletű vegyület által alkotott csoportból kiválasztottlegalább egy vegyület tartalmaz. A hatóanyag előnyösen részecskékformájában van jelen, amelyeknek részecskemérete kisebb, mint 200 m ésaz átlagos részecskeméret nagyobb, mint 10 m, és a készítmény legalábbegy gyógyszerészetileg elfogadható savat is tartalmazhat. Ó
HU0003330A 1997-05-07 1998-05-06 Pharmaceutical compositions containing tizoxanide and nitazoxanide HU229641B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/852,447 US5968961A (en) 1997-05-07 1997-05-07 Pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,809 US5965590A (en) 1994-09-08 1997-07-03 Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide
US08/887,810 US5856348A (en) 1994-09-08 1997-07-03 Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide
PCT/US1998/009229 WO1998050035A1 (en) 1997-05-07 1998-05-06 Pharmaceutical compositions of tizoxanide and nitazoxanide

Publications (3)

Publication Number Publication Date
HUP0003330A2 true HUP0003330A2 (hu) 2001-05-28
HUP0003330A3 HUP0003330A3 (en) 2002-10-28
HU229641B1 HU229641B1 (en) 2014-03-28

Family

ID=27420362

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0003330A HU229641B1 (en) 1997-05-07 1998-05-06 Pharmaceutical compositions containing tizoxanide and nitazoxanide

Country Status (35)

Country Link
EP (2) EP1222921B1 (hu)
JP (1) JP3739802B2 (hu)
KR (2) KR100576646B1 (hu)
CN (2) CN100515420C (hu)
AP (1) AP1103A (hu)
AR (1) AR057242A2 (hu)
AT (2) ATE228839T1 (hu)
AU (1) AU740022B2 (hu)
BG (2) BG109365A (hu)
BR (1) BR9808722A (hu)
CA (2) CA2288003C (hu)
CZ (2) CZ298270B6 (hu)
DE (2) DE69827417T2 (hu)
DK (2) DK1005342T3 (hu)
EA (2) EA002920B1 (hu)
EE (1) EE04870B1 (hu)
ES (2) ES2150404T3 (hu)
GE (1) GEP20032970B (hu)
HK (1) HK1025907A1 (hu)
HU (1) HU229641B1 (hu)
IL (2) IL132516A (hu)
IS (1) IS2087B (hu)
LV (1) LV12492B (hu)
ME (1) ME00530B (hu)
NO (2) NO313983B1 (hu)
NZ (2) NZ513881A (hu)
OA (1) OA11169A (hu)
PL (1) PL193275B1 (hu)
PT (2) PT1005342E (hu)
RO (1) RO120605B1 (hu)
SI (1) SI20149B (hu)
SK (2) SK283947B6 (hu)
TR (1) TR199902733T2 (hu)
UA (2) UA57079C2 (hu)
WO (1) WO1998050035A1 (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2467321A1 (en) 2004-05-14 2005-11-14 Paul J. Santerre Polymeric coupling agents and pharmaceutically-active polymers made therefrom
CN101448497B (zh) 2006-01-09 2013-07-10 罗马克实验室有限公司 包含硝唑尼特、替唑尼特、或其混合物的组合物在制备治疗丙型肝炎药物中的应用
EP2395840B1 (en) * 2009-02-13 2020-04-15 Romark Laboratories, L.C. Controlled release pharmaceutical formulations of nitazoxanide
AU2010247816B2 (en) 2009-05-12 2015-12-17 Romark Laboratories L.C. Haloalkyl heteroaryl benzamide compounds
AP2012006064A0 (en) 2009-06-26 2012-02-29 Romark Lab Lc Compounds and methods for treating influenza.
WO2013110975A1 (es) 2012-01-27 2013-08-01 Siegfried Rhein S.A. De C.V. Composición de nitazoxanida mejorada y proceso para prepararla
EP3217795A4 (en) * 2014-11-11 2018-08-22 Romark Laboratories, L.C. Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof
JP7502186B2 (ja) 2018-02-02 2024-06-18 リップル セラピューティクス コーポレーション ステロイド二量体を含むガラス製剤およびその使用
CN115956083A (zh) 2020-05-01 2023-04-11 波纹疗法公司 异二聚体组合物及用于治疗眼部病症的方法
WO2022130406A1 (en) * 2020-12-15 2022-06-23 Cipla Limited Inhalation composition of nitazoxanide or its derivatives for use in coronavirus disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1437800A (en) * 1973-08-08 1976-06-03 Phavic Sprl Derivatives of 2-benzamido-5-nitro-thiazoles
US4315018A (en) * 1978-12-07 1982-02-09 Rossignol Jean F Specific parasiticidal use of 2-benzamido-5-nitro-thiazole derivatives
US5578621A (en) * 1994-09-08 1996-11-26 Romark Lab Lc Benzamide derivatives
US5387598A (en) * 1994-04-13 1995-02-07 Rossignol; Jean-Francois Composition and galenic formulation suitable for combatting affections of the lower abdomen

Also Published As

Publication number Publication date
NO20021832D0 (no) 2002-04-18
AU7289598A (en) 1998-11-27
CN1158074C (zh) 2004-07-21
IS5223A (is) 1999-10-19
IL155799A0 (en) 2003-12-23
CA2288003C (en) 2003-10-21
CZ298270B6 (cs) 2007-08-08
NZ500149A (en) 2001-11-30
EA200100956A1 (ru) 2002-02-28
NZ513881A (en) 2002-10-25
EA199901012A1 (ru) 2000-08-28
KR100576646B1 (ko) 2006-05-08
JP3739802B2 (ja) 2006-01-25
BR9808722A (pt) 2000-07-11
SK151199A3 (en) 2000-07-11
CZ298269B6 (cs) 2007-08-08
OA11169A (en) 2003-04-25
EP1222921A1 (en) 2002-07-17
JP2001503067A (ja) 2001-03-06
EP1005342A1 (en) 2000-06-07
IL155799A (en) 2004-08-31
ATE228839T1 (de) 2002-12-15
IL132516A0 (en) 2001-03-19
LV12492A (en) 2000-06-20
RO120605B1 (ro) 2006-05-30
TR199902733T2 (xx) 2000-03-21
ES2232687T3 (es) 2005-06-01
DE69827417T2 (de) 2005-10-27
ATE281166T1 (de) 2004-11-15
EE9900578A (et) 2000-08-15
ES2150404T1 (es) 2000-12-01
AP1103A (en) 2002-09-04
DK1222921T3 (da) 2005-03-07
CN1552322A (zh) 2004-12-08
KR100426657B1 (ko) 2004-04-13
ES2150404T3 (es) 2003-07-01
EP1005342B1 (en) 2002-12-04
BG103958A (en) 2000-07-31
NO995406D0 (no) 1999-11-04
IL132516A (en) 2003-12-10
CA2418634A1 (en) 1998-11-12
NO20021832L (no) 2000-01-04
HK1025907A1 (en) 2000-12-01
PT1005342E (pt) 2003-02-28
CN1255060A (zh) 2000-05-31
SK283947B6 (sk) 2004-05-04
EP1005342A4 (en) 2001-02-07
NO995406L (no) 2000-01-04
IS2087B (is) 2006-03-15
LV12492B (en) 2001-01-20
PL193275B1 (pl) 2007-01-31
SI20149A (sl) 2000-08-31
HU229641B1 (en) 2014-03-28
DE69827417D1 (de) 2004-12-09
HUP0003330A3 (en) 2002-10-28
CA2288003A1 (en) 1998-11-12
GEP20032970B (en) 2003-05-27
SK283946B6 (sk) 2004-05-04
EA002920B1 (ru) 2002-10-31
DE69809928D1 (de) 2003-01-16
KR20010020322A (ko) 2001-03-15
PT1222921E (pt) 2005-02-28
NO335781B1 (no) 2015-02-16
EP1222921B1 (en) 2004-11-03
AU740022B2 (en) 2001-10-25
BG64973B1 (bg) 2006-11-30
AP9901675A0 (en) 1999-12-31
CA2418634C (en) 2004-10-26
SI20149B (en) 2001-08-31
BG109365A (en) 2006-08-31
DE69809928T2 (de) 2003-04-24
UA57079C2 (uk) 2003-06-16
NO313983B1 (no) 2003-01-13
PL336805A1 (en) 2000-07-17
KR20040004544A (ko) 2004-01-13
EA002908B1 (ru) 2002-10-31
UA74388C2 (uk) 2005-12-15
WO1998050035A1 (en) 1998-11-12
EE04870B1 (et) 2007-08-15
AR057242A2 (es) 2007-11-21
CZ391199A3 (cs) 2000-07-12
DK1005342T3 (da) 2003-03-24
ME00530B (me) 2011-10-10
CN100515420C (zh) 2009-07-22

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Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees