IL55168A - 6,6-dimethyl-2-substituted-1h-imidazo(4,5)isoquinoline-7,9 (6h,8h)-dione derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

6,6-dimethyl-2-substituted-1h-imidazo(4,5)isoquinoline-7,9 (6h,8h)-dione derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL55168A
Authority: IL; Israel
Prior art keywords: imidazo; isoquinoline; dimethyl; substituted; preparation
Prior art date: 1977-07-21

Application number

IL55168A

Other languages

English (en)

Other versions

IL55168A0 (en

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-07-21

Filing date

1978-07-19

Publication date

1981-09-13

1977-07-21 Priority claimed from DE19772732951 external-priority patent/DE2732951A1/de

1977-07-21 Priority claimed from DE2732906A external-priority patent/DE2732906C2/de

1978-07-19 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1978-09-29 Publication of IL55168A0 publication Critical patent/IL55168A0/xx

1981-09-13 Publication of IL55168A publication Critical patent/IL55168A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

IL55168A 1977-07-21 1978-07-19 6,6-dimethyl-2-substituted-1h-imidazo(4,5)isoquinoline-7,9 (6h,8h)-dione derivatives,their preparation and pharmaceutical compositions containing them IL55168A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19772732951 DE2732951A1 (de)	1977-07-21	1977-07-21	Neue imidazo-isochinolin-dione
DE2732906A DE2732906C2 (de)	1977-07-21	1977-07-21	In 5-Stellung durch einen Aminoalkylrest substituierte Imidazo-isochinolin-dione, Verfahren zu ihrer Herstellung und Arzneimittel

Publications (2)

Publication Number	Publication Date
IL55168A0 IL55168A0 (en)	1978-09-29
IL55168A true IL55168A (en)	1981-09-13

Family

ID=25772367

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL55168A IL55168A (en)	1977-07-21	1978-07-19	6,6-dimethyl-2-substituted-1h-imidazo(4,5)isoquinoline-7,9 (6h,8h)-dione derivatives,their preparation and pharmaceutical compositions containing them

Country Status (29)

Country	Link
US (1)	US4176184A (it)
JP (1)	JPS5422400A (it)
AT (1)	AT366383B (it)
AU (1)	AU519769B2 (it)
BG (1)	BG30021A3 (it)
CA (1)	CA1091232A (it)
CH (1)	CH642367A5 (it)
CS (1)	CS204032B2 (it)
DD (1)	DD137933A5 (it)
DK (1)	DK323378A (it)
ES (4)	ES471254A1 (it)
FI (1)	FI64371C (it)
FR (1)	FR2398069A1 (it)
GB (1)	GB2002751B (it)
GR (1)	GR65025B (it)
HK (1)	HK20685A (it)
HU (1)	HU181000B (it)
IL (1)	IL55168A (it)
IT (1)	IT1107653B (it)
LU (1)	LU80001A1 (it)
NL (1)	NL7807760A (it)
NO (1)	NO149314C (it)
NZ (1)	NZ187916A (it)
PL (1)	PL110398B1 (it)
PT (1)	PT68329A (it)
SE (1)	SE441746B (it)
SG (1)	SG185G (it)
SU (1)	SU688129A3 (it)
YU (1)	YU40340B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3531678A1 (de) *	1985-09-05	1987-03-12	Boehringer Mannheim Gmbh	Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JP2558707Y2 (ja) *	1986-06-25	1998-01-14	松下電工株式会社	蓄積式防排煙受信機
DE4027592A1 (de) *	1990-08-31	1992-03-05	Beiersdorf Ag	Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
DE19918211A1 (de)	1999-04-22	2000-10-26	Basf Ag	Cycloalkylsubstituierte Benzimidazole, deren Herstellung und Anwendung
US6506769B2 (en) *	1999-10-06	2003-01-14	Boehringer Ingelheim Pharmaceuticals, Inc.	Heterocyclic compounds useful as inhibitors of tyrosine kinases
JP5036112B2 (ja) *	1999-10-06	2012-09-26	ベーリンガーインゲルハイムファーマシューティカルズインコーポレイテッド	チロシンキナーゼのインヒビターとして有益な複素環化合物
WO2002014319A2 (en) *	2000-08-11	2002-02-21	Boehringer Ingelheim Pharmaceuticals, Inc.	Heterocyclic compounds useful as inhibitors of tyrosine kinases
EP1682547B1 (en) *	2003-10-30	2012-10-24	Boehringer Ingelheim (Canada) Ltd.	Rsv polymerase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE368009B (it) *	1971-09-16	1974-06-17	Kabi Ab
US3919238A (en) *	1973-06-06	1975-11-11	Morton Norwich Products Inc	9-(Substituted amino)imidazo(4,5-f) quinolines
US3878206A (en) *	1973-06-06	1975-04-15	Morton Norwich Products Inc	9-(Substituted amino)imidazo{8 4,5-f{9 quinolines

1978
- 1978-06-07 GR GR56730A patent/GR65025B/el unknown
- 1978-06-22 FI FI782011A patent/FI64371C/fi not_active IP Right Cessation
- 1978-06-29 ES ES471254A patent/ES471254A1/es not_active Expired
- 1978-07-11 AT AT0498878A patent/AT366383B/de active
- 1978-07-12 BG BG040381A patent/BG30021A3/xx unknown
- 1978-07-17 IT IT50337/78A patent/IT1107653B/it active
- 1978-07-17 US US05/925,461 patent/US4176184A/en not_active Expired - Lifetime
- 1978-07-18 CH CH772778A patent/CH642367A5/de not_active IP Right Cessation
- 1978-07-19 DK DK323378A patent/DK323378A/da not_active Application Discontinuation
- 1978-07-19 LU LU80001A patent/LU80001A1/de unknown
- 1978-07-19 CA CA307,712A patent/CA1091232A/en not_active Expired
- 1978-07-19 IL IL55168A patent/IL55168A/xx unknown
- 1978-07-19 DD DD78206810A patent/DD137933A5/xx unknown
- 1978-07-19 SU SU782636902A patent/SU688129A3/ru active
- 1978-07-19 CS CS784822A patent/CS204032B2/cs unknown
- 1978-07-20 HU HU78TO1085A patent/HU181000B/hu unknown
- 1978-07-20 PT PT68329A patent/PT68329A/pt unknown
- 1978-07-20 NL NL7807760A patent/NL7807760A/xx not_active Application Discontinuation
- 1978-07-20 GB GB7830585A patent/GB2002751B/en not_active Expired
- 1978-07-20 YU YU1747/78A patent/YU40340B/xx unknown
- 1978-07-20 PL PL1978208543A patent/PL110398B1/pl unknown
- 1978-07-20 JP JP8889578A patent/JPS5422400A/ja active Granted
- 1978-07-20 NO NO782498A patent/NO149314C/no unknown
- 1978-07-20 AU AU38210/78A patent/AU519769B2/en not_active Expired
- 1978-07-20 SE SE7808018A patent/SE441746B/sv not_active IP Right Cessation
- 1978-07-20 NZ NZ187916A patent/NZ187916A/xx unknown
- 1978-07-21 FR FR7821745A patent/FR2398069A1/fr active Granted
- 1978-12-20 ES ES476167A patent/ES476167A1/es not_active Expired
- 1978-12-20 ES ES476166A patent/ES476166A1/es not_active Expired
- 1978-12-20 ES ES476168A patent/ES476168A1/es not_active Expired
1985
- 1985-01-03 SG SG1/85A patent/SG185G/en unknown
- 1985-03-21 HK HK206/85A patent/HK20685A/xx unknown

Also Published As

Publication number	Publication date
ES471254A1 (es)	1979-10-01
IL55168A0 (en)	1978-09-29
SE441746B (sv)	1985-11-04
PT68329A (de)	1978-08-01
JPS6112912B2 (it)	1986-04-10
JPS5422400A (en)	1979-02-20
HK20685A (en)	1985-03-29
AU3821078A (en)	1980-01-24
GB2002751B (en)	1982-02-10
GB2002751A (en)	1979-02-28
US4176184A (en)	1979-11-27
FI64371C (fi)	1983-11-10
NO782498L (no)	1979-01-23
FR2398069B1 (it)	1981-05-22
SE7808018L (sv)	1979-01-22
ES476166A1 (es)	1979-06-01
ES476167A1 (es)	1979-04-16
IT7850337A0 (it)	1978-07-17
NZ187916A (en)	1981-05-01
NO149314C (no)	1984-03-28
YU174778A (en)	1983-02-28
AT366383B (de)	1982-04-13
GR65025B (en)	1980-06-16
PL208543A1 (pl)	1979-05-21
CS204032B2 (en)	1981-03-31
SU688129A3 (ru)	1979-09-25
SG185G (en)	1985-06-14
DD137933A5 (de)	1979-10-03
HU181000B (en)	1983-05-30
BG30021A3 (en)	1981-03-16
CH642367A5 (de)	1984-04-13
NO149314B (no)	1983-12-19
ES476168A1 (es)	1979-05-16
FI782011A (fi)	1979-01-22
YU40340B (en)	1985-12-31
ATA498878A (de)	1981-08-15
AU519769B2 (en)	1981-12-24
NL7807760A (nl)	1979-01-23
LU80001A1 (de)	1979-09-06
FR2398069A1 (fr)	1979-02-16
PL110398B1 (en)	1980-07-31
FI64371B (fi)	1983-07-29
IT1107653B (it)	1985-11-25
CA1091232A (en)	1980-12-09
DK323378A (da)	1979-01-22

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