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ES471254A1 - Procedimiento para la preparacion de nuevas imidazo-isoqui- nolein-dionas - Google Patents

Procedimiento para la preparacion de nuevas imidazo-isoqui- nolein-dionas

Info

Publication number
ES471254A1
ES471254A1 ES471254A ES471254A ES471254A1 ES 471254 A1 ES471254 A1 ES 471254A1 ES 471254 A ES471254 A ES 471254A ES 471254 A ES471254 A ES 471254A ES 471254 A1 ES471254 A1 ES 471254A1
Authority
ES
Spain
Prior art keywords
lower alkyl
salts
hydrogen
compounds
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES471254A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2732906A external-priority patent/DE2732906C2/de
Priority claimed from DE19772732951 external-priority patent/DE2732951A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES471254A1 publication Critical patent/ES471254A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Procedimiento para la preparación de nuevas imidazo-isoquinoleín-dionas de la fórmula general **(Fórmula)** en la que R1 significa un grupo alcohilo inferior eventualmente sustituido con un grupo fenilo, un grupo cicloalcohilo con 3 hasta 6 átomos de carbono o un grupo fenilo, eventualmente monosustituido o disustituido con átomos de halógeno, grupos hidroxi, metoxi, metilmercapto, metilsulfinilo, metilsulfonilo y/o benciloxi, pudiendo ser los sustituyentes iguales o diferentes, y a significa un átomo de hidrógeno.
ES471254A 1977-07-21 1978-06-29 Procedimiento para la preparacion de nuevas imidazo-isoqui- nolein-dionas Expired ES471254A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2732906A DE2732906C2 (de) 1977-07-21 1977-07-21 In 5-Stellung durch einen Aminoalkylrest substituierte Imidazo-isochinolin-dione, Verfahren zu ihrer Herstellung und Arzneimittel
DE19772732951 DE2732951A1 (de) 1977-07-21 1977-07-21 Neue imidazo-isochinolin-dione

Publications (1)

Publication Number Publication Date
ES471254A1 true ES471254A1 (es) 1979-10-01

Family

ID=25772367

Family Applications (4)

Application Number Title Priority Date Filing Date
ES471254A Expired ES471254A1 (es) 1977-07-21 1978-06-29 Procedimiento para la preparacion de nuevas imidazo-isoqui- nolein-dionas
ES476166A Expired ES476166A1 (es) 1977-07-21 1978-12-20 Procedimiento para la preparacion de nuevas imidazo-isoqui- nolein-dionas
ES476168A Expired ES476168A1 (es) 1977-07-21 1978-12-20 Procedimiento para la preparacion de nuevas imidazo-isoquinoleindionas.
ES476167A Expired ES476167A1 (es) 1977-07-21 1978-12-20 Procedimiento para la preparacion de nuevas imidazo-isoquinolein-dionas.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES476166A Expired ES476166A1 (es) 1977-07-21 1978-12-20 Procedimiento para la preparacion de nuevas imidazo-isoqui- nolein-dionas
ES476168A Expired ES476168A1 (es) 1977-07-21 1978-12-20 Procedimiento para la preparacion de nuevas imidazo-isoquinoleindionas.
ES476167A Expired ES476167A1 (es) 1977-07-21 1978-12-20 Procedimiento para la preparacion de nuevas imidazo-isoquinolein-dionas.

Country Status (29)

Country Link
US (1) US4176184A (es)
JP (1) JPS5422400A (es)
AT (1) AT366383B (es)
AU (1) AU519769B2 (es)
BG (1) BG30021A3 (es)
CA (1) CA1091232A (es)
CH (1) CH642367A5 (es)
CS (1) CS204032B2 (es)
DD (1) DD137933A5 (es)
DK (1) DK323378A (es)
ES (4) ES471254A1 (es)
FI (1) FI64371C (es)
FR (1) FR2398069A1 (es)
GB (1) GB2002751B (es)
GR (1) GR65025B (es)
HK (1) HK20685A (es)
HU (1) HU181000B (es)
IL (1) IL55168A (es)
IT (1) IT1107653B (es)
LU (1) LU80001A1 (es)
NL (1) NL7807760A (es)
NO (1) NO149314C (es)
NZ (1) NZ187916A (es)
PL (1) PL110398B1 (es)
PT (1) PT68329A (es)
SE (1) SE441746B (es)
SG (1) SG185G (es)
SU (1) SU688129A3 (es)
YU (1) YU40340B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JP2558707Y2 (ja) * 1986-06-25 1998-01-14 松下電工 株式会社 蓄積式防排煙受信機
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
DE19918211A1 (de) 1999-04-22 2000-10-26 Basf Ag Cycloalkylsubstituierte Benzimidazole, deren Herstellung und Anwendung
US6506769B2 (en) * 1999-10-06 2003-01-14 Boehringer Ingelheim Pharmaceuticals, Inc. Heterocyclic compounds useful as inhibitors of tyrosine kinases
ATE277044T1 (de) * 1999-10-06 2004-10-15 Boehringer Ingelheim Pharma Heterocyclische verbindungen verwendbar als tyrosinkinase inhibitoren
WO2002014319A2 (en) * 2000-08-11 2002-02-21 Boehringer Ingelheim Pharmaceuticals, Inc. Heterocyclic compounds useful as inhibitors of tyrosine kinases
EP1682547B1 (en) * 2003-10-30 2012-10-24 Boehringer Ingelheim (Canada) Ltd. Rsv polymerase inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE368009B (es) * 1971-09-16 1974-06-17 Kabi Ab
US3878206A (en) * 1973-06-06 1975-04-15 Morton Norwich Products Inc 9-(Substituted amino)imidazo{8 4,5-f{9 quinolines
US3919238A (en) * 1973-06-06 1975-11-11 Morton Norwich Products Inc 9-(Substituted amino)imidazo(4,5-f) quinolines

Also Published As

Publication number Publication date
ES476166A1 (es) 1979-06-01
FI64371C (fi) 1983-11-10
GB2002751B (en) 1982-02-10
SE441746B (sv) 1985-11-04
YU40340B (en) 1985-12-31
PT68329A (de) 1978-08-01
IT7850337A0 (it) 1978-07-17
FR2398069B1 (es) 1981-05-22
CA1091232A (en) 1980-12-09
SE7808018L (sv) 1979-01-22
JPS6112912B2 (es) 1986-04-10
AU519769B2 (en) 1981-12-24
IL55168A (en) 1981-09-13
FI64371B (fi) 1983-07-29
DK323378A (da) 1979-01-22
CH642367A5 (de) 1984-04-13
SG185G (en) 1985-06-14
HK20685A (en) 1985-03-29
NO782498L (no) 1979-01-23
GB2002751A (en) 1979-02-28
IL55168A0 (en) 1978-09-29
AU3821078A (en) 1980-01-24
GR65025B (en) 1980-06-16
CS204032B2 (en) 1981-03-31
JPS5422400A (en) 1979-02-20
HU181000B (en) 1983-05-30
NO149314B (no) 1983-12-19
LU80001A1 (de) 1979-09-06
ATA498878A (de) 1981-08-15
IT1107653B (it) 1985-11-25
YU174778A (en) 1983-02-28
DD137933A5 (de) 1979-10-03
NL7807760A (nl) 1979-01-23
ES476168A1 (es) 1979-05-16
ES476167A1 (es) 1979-04-16
FI782011A (fi) 1979-01-22
NZ187916A (en) 1981-05-01
PL110398B1 (en) 1980-07-31
BG30021A3 (en) 1981-03-16
FR2398069A1 (fr) 1979-02-16
SU688129A3 (ru) 1979-09-25
NO149314C (no) 1984-03-28
PL208543A1 (pl) 1979-05-21
AT366383B (de) 1982-04-13
US4176184A (en) 1979-11-27

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000601