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MX2017009182A - Sistemas de receptor de antigeno quimerico impulsado por mab para clasificar/reducir celulas inmunes diseñadas. - Google Patents

Sistemas de receptor de antigeno quimerico impulsado por mab para clasificar/reducir celulas inmunes diseñadas.

Info

Publication number
MX2017009182A
MX2017009182A MX2017009182A MX2017009182A MX2017009182A MX 2017009182 A MX2017009182 A MX 2017009182A MX 2017009182 A MX2017009182 A MX 2017009182A MX 2017009182 A MX2017009182 A MX 2017009182A MX 2017009182 A MX2017009182 A MX 2017009182A
Authority
MX
Mexico
Prior art keywords
mab
sorting
antigen receptor
chimeric antigen
immune cells
Prior art date
Application number
MX2017009182A
Other languages
English (en)
Inventor
Duchateau Philippe
Juillerat Alexandre
Johnson Sasu Barbra
Rajpal Arvind
Valton Julien
Original Assignee
Cellectis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellectis filed Critical Cellectis
Publication of MX2017009182A publication Critical patent/MX2017009182A/es

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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
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Abstract

Un polipéptido que codifica un receptor de antígeno quimérico (CAR) que comprende al menos un dominio de unión extracelular que comprende un scFv formado por al menos una cadena de VH y una cadena de VL específicas a un antígeno, en donde el dominio de unión extracelular comprende al menos un epítopo específico de mAb.
MX2017009182A 2015-01-26 2016-01-25 Sistemas de receptor de antigeno quimerico impulsado por mab para clasificar/reducir celulas inmunes diseñadas. MX2017009182A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201570044 2015-01-26
PCT/EP2016/051467 WO2016120216A1 (en) 2015-01-26 2016-01-25 mAb-DRIVEN CHIMERIC ANTIGEN RECEPTOR SYSTEMS FOR SORTING/DEPLETING ENGINEERED IMMUNE CELLS

Publications (1)

Publication Number Publication Date
MX2017009182A true MX2017009182A (es) 2018-04-20

Family

ID=52396337

Family Applications (3)

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MX2017009182A MX2017009182A (es) 2015-01-26 2016-01-25 Sistemas de receptor de antigeno quimerico impulsado por mab para clasificar/reducir celulas inmunes diseñadas.
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