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BR112017014547A2 - sistemas de receptor de antígeno quimérico dirigidos por mab para classificação/depleção de células imunes engenheiradas - Google Patents

sistemas de receptor de antígeno quimérico dirigidos por mab para classificação/depleção de células imunes engenheiradas

Info

Publication number
BR112017014547A2
BR112017014547A2 BR112017014547-2A BR112017014547A BR112017014547A2 BR 112017014547 A2 BR112017014547 A2 BR 112017014547A2 BR 112017014547 A BR112017014547 A BR 112017014547A BR 112017014547 A2 BR112017014547 A2 BR 112017014547A2
Authority
BR
Brazil
Prior art keywords
depletion
chimeric antigen
immune cell
antigen receptor
engineered immune
Prior art date
Application number
BR112017014547-2A
Other languages
English (en)
Inventor
Johnson Sasu Barbra
Rajpal Arvind
Duchateau Philippe
Juillerat Alexandre
Valton Julien
Original Assignee
Cellectis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellectis filed Critical Cellectis
Publication of BR112017014547A2 publication Critical patent/BR112017014547A2/pt

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Abstract

um polipeptídeo que codifica um receptor de antígeno quimérico (car) compreendendo pelo menos um domínio de ligação extracelular que compreende um scfv formado por pelo menos uma cadeia vh e uma cadeia vl específicas para um antígeno, em que o dito domínio de ligação extracelular compreende pelo menos um epitopo específico de mab.
BR112017014547-2A 2015-01-26 2016-01-25 sistemas de receptor de antígeno quimérico dirigidos por mab para classificação/depleção de células imunes engenheiradas BR112017014547A2 (pt)

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DKPA201570044 2015-01-26
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PCT/EP2016/051467 WO2016120216A1 (en) 2015-01-26 2016-01-25 mAb-DRIVEN CHIMERIC ANTIGEN RECEPTOR SYSTEMS FOR SORTING/DEPLETING ENGINEERED IMMUNE CELLS

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BR112017015453-6A BR112017015453A2 (pt) 2015-01-26 2016-01-25 células imunes modificadas knockout para receptor de células t, dotadas de receptores quiméricos de antígeno, de ligação a cd123 para o tratamento de linfoma mieloide agudo recorrente/refratário ou neoplasia blástica de células dendríticas plasmacitoides
BR112017014547-2A BR112017014547A2 (pt) 2015-01-26 2016-01-25 sistemas de receptor de antígeno quimérico dirigidos por mab para classificação/depleção de células imunes engenheiradas
BR112017013981-2A BR112017013981A2 (pt) 2015-01-26 2016-01-25 receptores antigênicos quiméricos com uma única cadeia específicos anti-cll1 (sccars) para imunoterapia de câncer

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AU2016212158A1 (en) 2017-07-13
CN107406516A (zh) 2017-11-28
CA2973524A1 (en) 2016-08-04
RU2017129455A (ru) 2019-03-04
MX2017009182A (es) 2018-04-20
JP6779909B2 (ja) 2020-11-04
US20180000914A1 (en) 2018-01-04
AU2016212160B2 (en) 2021-04-15
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IL253049A0 (en) 2017-08-31
IL253012A0 (en) 2017-08-31
RU2017129591A (ru) 2019-03-04
IL253049B (en) 2022-01-01
IL252937A0 (en) 2017-08-31
CN107406516B (zh) 2021-11-23
CN113968914A (zh) 2022-01-25
IL252937B (en) 2021-09-30
CA2973525C (en) 2021-12-14
CN107438618A (zh) 2017-12-05
MX2017009181A (es) 2017-11-22
EP3250605A1 (en) 2017-12-06
JP2018504459A (ja) 2018-02-15
CA2973525A1 (en) 2016-08-04
WO2016120220A1 (en) 2016-08-04
CA2973642A1 (en) 2016-08-04
WO2016120216A1 (en) 2016-08-04
US20180002435A1 (en) 2018-01-04
BR112017015453A2 (pt) 2018-01-23
KR20170135822A (ko) 2017-12-08
JP6884709B2 (ja) 2021-06-09
WO2016120219A1 (en) 2016-08-04
EP3250606B1 (en) 2020-11-25
MX2017009349A (es) 2017-09-26
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EP3250602A1 (en) 2017-12-06
RU2017129592A3 (pt) 2019-07-17
DK3250604T3 (da) 2021-07-12
JP2018504143A (ja) 2018-02-15
US20180009895A1 (en) 2018-01-11
EP3250607A1 (en) 2017-12-06
AU2016212161A1 (en) 2017-07-13
DK3250606T3 (da) 2021-01-04
RU2017129592A (ru) 2019-02-28
RU2017129591A3 (pt) 2019-08-05
AU2016212159A1 (en) 2017-07-13
KR102661969B1 (ko) 2024-04-29
EP3250604A1 (en) 2017-12-06
RU2731543C2 (ru) 2020-09-04
KR102329836B1 (ko) 2021-11-19
JP2018504458A (ja) 2018-02-15

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