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LT3513793T - Heterociklilaminai, kaip pi3k inhibitoriai - Google Patents

Heterociklilaminai, kaip pi3k inhibitoriai

Info

Publication number
LT3513793T
LT3513793T LTEP18215449.2T LT18215449T LT3513793T LT 3513793 T LT3513793 T LT 3513793T LT 18215449 T LT18215449 T LT 18215449T LT 3513793 T LT3513793 T LT 3513793T
Authority
LT
Lithuania
Prior art keywords
heterocyclylamines
pi3k inhibitors
pi3k
inhibitors
Prior art date
Application number
LTEP18215449.2T
Other languages
English (en)
Inventor
Yun-Long Li
Wenqing Yao
Andrew Combs
Eddy Yue
Song MEI
Wenyu Zhu
Joseph Glenn
Thomas MADUSKUIE
Richard Sparks
Brent Douty
Chunhong He
Original Assignee
Incyte Holdings Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Holdings Corporation filed Critical Incyte Holdings Corporation
Publication of LT3513793T publication Critical patent/LT3513793T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LTEP18215449.2T 2011-09-02 2012-08-31 Heterociklilaminai, kaip pi3k inhibitoriai LT3513793T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161530866P 2011-09-02 2011-09-02
US201261594882P 2012-02-03 2012-02-03
US201261677445P 2012-07-30 2012-07-30

Publications (1)

Publication Number Publication Date
LT3513793T true LT3513793T (lt) 2021-06-10

Family

ID=47071429

Family Applications (3)

Application Number Title Priority Date Filing Date
LTEP16199883.6T LT3196202T (lt) 2011-09-02 2012-08-31 Heterociklilaminai, kaip pi3k slopikliai
LTEP12775861.3T LT2751109T (lt) 2011-09-02 2012-08-31 Heterociklilaminai kaip pi3k inhibitoriai
LTEP18215449.2T LT3513793T (lt) 2011-09-02 2012-08-31 Heterociklilaminai, kaip pi3k inhibitoriai

Family Applications Before (2)

Application Number Title Priority Date Filing Date
LTEP16199883.6T LT3196202T (lt) 2011-09-02 2012-08-31 Heterociklilaminai, kaip pi3k slopikliai
LTEP12775861.3T LT2751109T (lt) 2011-09-02 2012-08-31 Heterociklilaminai kaip pi3k inhibitoriai

Country Status (38)

Country Link
US (9) US9199982B2 (lt)
EP (4) EP3513793B1 (lt)
JP (8) JP6067709B2 (lt)
KR (7) KR102030609B1 (lt)
CN (1) CN106986867B (lt)
AR (1) AR087760A1 (lt)
AU (5) AU2012301721B2 (lt)
BR (2) BR112014004971B1 (lt)
CA (1) CA2846652C (lt)
CL (1) CL2014000517A1 (lt)
CO (1) CO6910199A2 (lt)
CR (2) CR20180293A (lt)
CY (3) CY1118679T1 (lt)
DK (3) DK2751109T3 (lt)
EA (2) EA028890B1 (lt)
EC (1) ECSP14013274A (lt)
ES (3) ES2873001T3 (lt)
HK (1) HK1199644A1 (lt)
HR (3) HRP20170285T1 (lt)
HU (3) HUE053953T2 (lt)
IL (7) IL299533B1 (lt)
LT (3) LT3196202T (lt)
ME (2) ME02595B (lt)
MX (2) MX2020004502A (lt)
MY (1) MY179332A (lt)
NZ (1) NZ769326A (lt)
PE (2) PE20181272A1 (lt)
PH (2) PH12017501766B1 (lt)
PL (3) PL3196202T3 (lt)
PT (3) PT2751109T (lt)
RS (3) RS58817B1 (lt)
SG (3) SG11201400232WA (lt)
SI (3) SI3513793T1 (lt)
SM (1) SMT201700111B (lt)
TW (6) TWI543980B (lt)
UA (1) UA121539C2 (lt)
WO (1) WO2013033569A1 (lt)
ZA (1) ZA201904877B (lt)

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