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JP6165380B1 - 神経回路網の再構築・賦活剤 - Google Patents

神経回路網の再構築・賦活剤 Download PDF

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Publication number
JP6165380B1
JP6165380B1 JP2017503639A JP2017503639A JP6165380B1 JP 6165380 B1 JP6165380 B1 JP 6165380B1 JP 2017503639 A JP2017503639 A JP 2017503639A JP 2017503639 A JP2017503639 A JP 2017503639A JP 6165380 B1 JP6165380 B1 JP 6165380B1
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JPWO2017030167A1 (ja
Inventor
千尋 東田
千尋 東田
かつ子 小松
かつ子 小松
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RESILIO COMPANY LIMITED
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RESILIO COMPANY LIMITED
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254Acanthopanax or Eleutherococcus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2017503639A 2015-08-18 2016-08-18 神経回路網の再構築・賦活剤 Active JP6165380B1 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015161125 2015-08-18
JP2015161125 2015-08-18
PCT/JP2016/074130 WO2017030167A1 (fr) 2015-08-18 2016-08-18 Agent reconstructeur/activateur de réseau neuronal

Related Child Applications (1)

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JP2017119960A Division JP2017165775A (ja) 2015-08-18 2017-06-19 神経回路網の再構築・賦活剤

Publications (2)

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JP6165380B1 true JP6165380B1 (ja) 2017-07-19
JPWO2017030167A1 JPWO2017030167A1 (ja) 2017-08-17

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JP2017503639A Active JP6165380B1 (ja) 2015-08-18 2016-08-18 神経回路網の再構築・賦活剤
JP2017119960A Pending JP2017165775A (ja) 2015-08-18 2017-06-19 神経回路網の再構築・賦活剤

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JP2017119960A Pending JP2017165775A (ja) 2015-08-18 2017-06-19 神経回路網の再構築・賦活剤

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JP (2) JP6165380B1 (fr)
WO (1) WO2017030167A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201900037A (zh) * 2017-03-31 2019-01-01 日商太陽綠藻股份有限公司 學習效果改善劑及學習效果改善用食品組成物的製法
EP3572085A1 (fr) 2018-05-25 2019-11-27 Neuro-Sys Composition de combinaison synergétique comprenant une saponine stéroïdique, premier composé polyphénolique et éventuellement, second composé polyphénolique

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005510509A (ja) * 2001-11-06 2005-04-21 ザ キグリー コーポレーション 放射線障害の予防、軽減、及び治療用の栄養性サプリメント及びその方法
JP2007161606A (ja) * 2005-12-09 2007-06-28 Univ Of Tokyo 哺乳動物の海馬におけるニューロン新生を促進する組成物
JP2007230878A (ja) * 2006-02-27 2007-09-13 Pokka Corp 脳機能改善剤及びそれを含有する脳機能改善組成物
JP2008501343A (ja) * 2004-06-04 2008-01-24 ワシントン・ユニバーシティ 神経障害を治療するための方法および組成物
CN102078423A (zh) * 2010-12-29 2011-06-01 陈永洪 一种治疗骨质增生的外用中草药制剂
WO2014112145A1 (fr) * 2013-01-21 2014-07-24 レジリオ株式会社 Agent thérapeutique et procédé thérapeutique concernant 1,25d3-marrs pour une maladie neurologique telle que la maladie d'alzheimer
US20150132280A1 (en) * 2013-11-12 2015-05-14 Ortho-Nutra, Llc Theacrine-based supplement and method of use thereof
CN104825555A (zh) * 2015-04-23 2015-08-12 吴远华 一种预防帕金森病的药物、制备方法及制剂
JP2016027031A (ja) * 2014-07-01 2016-02-18 レジリオ株式会社 神経回路網の再構築・賦活用医薬または食品

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005510509A (ja) * 2001-11-06 2005-04-21 ザ キグリー コーポレーション 放射線障害の予防、軽減、及び治療用の栄養性サプリメント及びその方法
JP2008501343A (ja) * 2004-06-04 2008-01-24 ワシントン・ユニバーシティ 神経障害を治療するための方法および組成物
JP2007161606A (ja) * 2005-12-09 2007-06-28 Univ Of Tokyo 哺乳動物の海馬におけるニューロン新生を促進する組成物
JP2007230878A (ja) * 2006-02-27 2007-09-13 Pokka Corp 脳機能改善剤及びそれを含有する脳機能改善組成物
CN102078423A (zh) * 2010-12-29 2011-06-01 陈永洪 一种治疗骨质增生的外用中草药制剂
WO2014112145A1 (fr) * 2013-01-21 2014-07-24 レジリオ株式会社 Agent thérapeutique et procédé thérapeutique concernant 1,25d3-marrs pour une maladie neurologique telle que la maladie d'alzheimer
US20150132280A1 (en) * 2013-11-12 2015-05-14 Ortho-Nutra, Llc Theacrine-based supplement and method of use thereof
JP2016027031A (ja) * 2014-07-01 2016-02-18 レジリオ株式会社 神経回路網の再構築・賦活用医薬または食品
CN104825555A (zh) * 2015-04-23 2015-08-12 吴远华 一种预防帕金森病的药物、制备方法及制剂

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BAI YANJING ET AL: "Active components from Siberian ginseng (Eleutherococcus senticosus) for protection of amyloid β(25", J NAT MED, vol. 65, JPN6016035533, 2011, pages 417 - 423, ISSN: 0003535195 *
HEO JIN HO ET AL: "Effect of Antioxidant Flavanone, Naringenin, from Citrus junos on Neuroprotection", J. AGRIC. FOOD CHEM., vol. 52, JPN6016035520, 2004, pages 1520 - 1525, XP055366274, ISSN: 0003535199, DOI: 10.1021/jf035079g *
KHAN BADRUZZAMAN M. ET AL: "Naringenin ameliorates Alzheimer's disease(AD)-type neurodegeneration with cognitive impairment(AD-T", NEUROCHEMISTRY INTERNATIONAL, vol. 61, JPN6016035517, 2012, pages 1081 - 1093, XP055366273, ISSN: 0003535198, DOI: 10.1016/j.neuint.2012.07.025 *
WANG MEI DONG ET AL: "Naringin Enhances CaMKII Activity and Improves Long-Term Memory in a Mouse Model of Alzheimer's Dise", INT. J. MOL. SCI., vol. 14, JPN6016035522, 2013, pages 5576 - 5586, XP055366278, ISSN: 0003535200, DOI: 10.3390/ijms14035576 *
WONG CHUN KA ET AL: "Drynaria fortunei-derived total flavonoid fraction and isolated compounds exert oestrogen-like prote", BRITISH JOURNAL OF NUTRITION, vol. 110, JPN6016035537, 2013, pages 475 - 485, XP055366287, ISSN: 0003535197, DOI: 10.1017/S0007114512005405 *
XINLUAN WANG ET AL: "Osteogenic effects of flavonoid aglycones from an osteoprotective fraction of Drynaria fortunei-An", PHYTOMEDICINE, vol. 18, JPN6016035535, 2011, pages 868 - 872, ISSN: 0003535196 *
ZHU HAN-YI ET AL., EFFECTS OF NARINGENIN ON LEARNING AND MEMORY DISORDER AND Β-AMYLOID PEPTIDE INDU, JPN6017012496, ISSN: 0003535201 *
東田 千尋ら: "刺五加メタノールエキスによるシナプス再形成作用と記憶障害改善作用", 日本薬学会年会要旨集, vol. 126, JPN6016035530, 2006, pages 130, ISSN: 0003535194 *

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WO2017030167A1 (fr) 2017-02-23
JPWO2017030167A1 (ja) 2017-08-17
JP2017165775A (ja) 2017-09-21

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