HRP20020652A2 - Use of il-18 inhibitors - Google Patents
Use of il-18 inhibitors Download PDFInfo
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- HRP20020652A2 HRP20020652A2 HRP20020652A HRP20020652A2 HR P20020652 A2 HRP20020652 A2 HR P20020652A2 HR P20020652 A HRP20020652 A HR P20020652A HR P20020652 A2 HRP20020652 A2 HR P20020652A2
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EP (1) | EP1257292B1 (sk) |
JP (1) | JP4744763B2 (sk) |
KR (3) | KR20070057282A (sk) |
CN (1) | CN1322897C (sk) |
AT (1) | ATE506959T1 (sk) |
AU (2) | AU2001240636B8 (sk) |
BG (1) | BG66134B1 (sk) |
BR (1) | BR0108514A (sk) |
CA (2) | CA2399298C (sk) |
CY (1) | CY1111687T1 (sk) |
CZ (1) | CZ304485B6 (sk) |
DE (1) | DE60144514D1 (sk) |
DK (1) | DK1257292T3 (sk) |
EA (1) | EA005583B1 (sk) |
EE (1) | EE05423B1 (sk) |
HK (1) | HK1051965A1 (sk) |
HR (1) | HRP20020652A2 (sk) |
HU (1) | HU227752B1 (sk) |
IL (2) | IL151388A0 (sk) |
ME (1) | ME00546B (sk) |
MX (1) | MXPA02008079A (sk) |
NO (1) | NO331971B1 (sk) |
NZ (3) | NZ546294A (sk) |
PL (1) | PL206549B1 (sk) |
PT (1) | PT1257292E (sk) |
RS (1) | RS51737B (sk) |
SI (1) | SI1257292T1 (sk) |
SK (1) | SK288032B6 (sk) |
TR (2) | TR200502508T2 (sk) |
WO (1) | WO2001062285A1 (sk) |
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AU2001236807A1 (en) * | 2000-02-10 | 2001-08-20 | Abbott Laboratories | Antibodies that bind human interleukin-18 and methods of making and using |
KR20070057282A (ko) * | 2000-02-21 | 2007-06-04 | 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. | Il-18 저해물질의 용도 |
US6894155B2 (en) | 2000-10-11 | 2005-05-17 | Viron Therapeutics | Nucleic acid molecules and polypeptides for immune modulation |
US7718368B2 (en) | 2000-12-04 | 2010-05-18 | Viron Therapeutics Inc. | Immunomodulatory protein and useful embodiments thereof |
BR0210904A (pt) * | 2001-05-16 | 2005-08-16 | Yeda Res & Dev | Uso de inibidores de il-18 para o tratamento ou prevenção de sepse |
MXPA04002565A (es) * | 2001-11-30 | 2004-05-31 | Pfizer Prod Inc | Combinacion de un inhibidor de il-1/18 con un inhibidor de tnf para el tratamiento de inflamacion. |
WO2004064713A2 (en) * | 2003-01-20 | 2004-08-05 | Vib Vzw | The use of yop preoteins or rho gtpase inhibitors as caspase-1 inhibitors |
JP4134166B2 (ja) * | 2003-04-30 | 2008-08-13 | 独立行政法人科学技術振興機構 | ヒト抗ヒトインターロイキン−18抗体およびその断片、並びにそれらの利用方法 |
CA2545733A1 (en) * | 2003-11-10 | 2005-05-26 | Vertex Pharmaceuticals Incorporated | Methods for monitoring il-18 |
US7968684B2 (en) * | 2003-11-12 | 2011-06-28 | Abbott Laboratories | IL-18 binding proteins |
NZ552908A (en) | 2004-06-30 | 2009-11-27 | Atsuo Sekiyama | Indicator agent for noninflammatory stress response and use thereof |
DK1808446T3 (da) * | 2004-07-16 | 2012-05-14 | Atsuo Sekiyama | IL-18-receptor-antagonist og farmaceutisk sammensætning indeholdende antagonisten |
SI2267024T1 (sl) | 2005-06-03 | 2012-09-28 | Ares Trading Sa | Proizvodnja rekombinantnega IL-18 vezavnega proteina |
ES2375831T3 (es) | 2005-06-10 | 2012-03-06 | Ares Trading S.A. | Procedimiento para la purificación de prote�?nas de unión a il-18. |
EP1746167A1 (en) * | 2005-07-20 | 2007-01-24 | Apoxis SA | Method for the identification of compounds susceptible to inhibit inflammation |
ES2514495T3 (es) | 2006-05-25 | 2014-10-28 | Glaxo Group Limited | Anticuerpos humanizados modificados anti-interleucina-18 |
US8440195B2 (en) * | 2010-11-12 | 2013-05-14 | National University Corporation Chiba University | Inhibition of CD69 for treatment of inflammatory conditions |
GB201213968D0 (en) * | 2012-08-06 | 2012-09-19 | Isis Innovation | Prevention and treatment of osteoarthritis |
KR102512797B1 (ko) * | 2013-09-05 | 2023-03-22 | 에이비2 바이오 에스에이 | 염증성 질환에서 il-18 결합 단백질(il-18bp) |
CN107660150B (zh) | 2015-03-05 | 2023-10-24 | Ab2生物股份有限公司 | Il-18结合蛋白(il-18bp)和抗体在炎性疾病中 |
CN106109497A (zh) * | 2016-07-25 | 2016-11-16 | 深圳爱生再生医学科技有限公司 | 治疗肝硬化的干细胞制剂 |
CN106834449B (zh) * | 2017-01-10 | 2019-04-30 | 东南大学 | 与原发性胆汁性胆管炎关联的白细胞介素21受体及其应用 |
CN112236453A (zh) * | 2018-06-14 | 2021-01-15 | 波尔多大学 | 使用白细胞介素-1抑制剂治疗胎盘慢性组织细胞绒毛间质炎 |
JPWO2023286694A1 (sk) | 2021-07-13 | 2023-01-19 | ||
CN117647645B (zh) * | 2024-01-29 | 2024-04-12 | 中国人民解放军总医院第一医学中心 | Lbp、atf6、m-csfr联用在制备诊断自身免疫性肝病产品中的应用及试剂盒 |
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Publication number | Priority date | Publication date | Assignee | Title |
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US5985863A (en) * | 1996-09-12 | 1999-11-16 | Vertex Pharmaceuticals, Inc. | Compositions and methods for decreasing IGIF and IFN-γ production by administering an ICE inhibitor |
US5116964A (en) * | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
US5744451A (en) * | 1995-09-12 | 1998-04-28 | Warner-Lambert Company | N-substituted glutamic acid derivatives with interleukin-1 β converting enzyme inhibitory activity |
EP0936923B1 (en) * | 1996-11-15 | 2003-12-17 | Kennedy Institute Of Rheumatology | SUPPRESSION OF TNFalpha AND IL-12 IN THERAPY |
US7141393B2 (en) * | 1996-12-26 | 2006-11-28 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Interleukin-18-receptor proteins |
JP4026923B2 (ja) * | 1997-03-12 | 2007-12-26 | 株式会社林原生物化学研究所 | ポリペプチド |
US6087116A (en) * | 1997-03-12 | 2000-07-11 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Interleukin-18 (IL-18) receptor polypeptides and their uses |
IL121860A0 (en) * | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
CA2276216A1 (en) * | 1998-06-24 | 1999-12-24 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | An artificial peptide capable of neutralizing the biological activity of interleukin-18 |
EP1110969A4 (en) * | 1998-09-01 | 2002-01-09 | Hayashibara Biochem Lab | INTERLEUKIN 18 BINDING PROTEIN |
AR022952A1 (es) * | 1999-03-19 | 2002-09-04 | Smithkline Beecham Corp | ANTICUERPO MONOCLONAL DE ROEDOR ESPECIFICAMENTE NEUTRALIZANTE PARA LA INTERLEUQUINA-18 HUMANA , UN FRAGMENTO FAB NEUTRALIZANTE o FRAGMENTO F(AB')2, UNA REGION DE COMPLEMENTARIEDAD DE CADENA LIGERA DE INMONOGLOBULINA(CDR), UNA MOLECULA DE ACIDO NUCLEICO, COMPOSICION FARMACEUTICA QUE LO COMPRENDE, EL |
AU2001236807A1 (en) * | 2000-02-10 | 2001-08-20 | Abbott Laboratories | Antibodies that bind human interleukin-18 and methods of making and using |
KR20070057282A (ko) * | 2000-02-21 | 2007-06-04 | 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. | Il-18 저해물질의 용도 |
WO2002032374A2 (en) * | 2000-10-18 | 2002-04-25 | Immunex Corporation | Methods for treating il-18 mediated disorders |
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