US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
CN101537180B
(zh)
|
2002-07-18 |
2016-02-10 |
莫鲁斯有限公司 |
抗体混合物的重组生产
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
JP4794301B2
(ja)
*
|
2003-06-11 |
2011-10-19 |
中外製薬株式会社 |
抗体の製造方法
|
AU2003271174A1
(en)
|
2003-10-10 |
2005-04-27 |
Chugai Seiyaku Kabushiki Kaisha |
Double specific antibodies substituting for functional protein
|
JPWO2005056602A1
(ja)
*
|
2003-12-12 |
2008-03-06 |
中外製薬株式会社 |
アゴニスト活性を有する改変抗体のスクリーニング方法
|
WO2005056605A1
(ja)
*
|
2003-12-12 |
2005-06-23 |
Chugai Seiyaku Kabushiki Kaisha |
3量体以上の受容体を認識する改変抗体
|
TW200530269A
(en)
*
|
2003-12-12 |
2005-09-16 |
Chugai Pharmaceutical Co Ltd |
Anti-Mpl antibodies
|
EP3623473A1
(en)
|
2005-03-31 |
2020-03-18 |
Chugai Seiyaku Kabushiki Kaisha |
Process for production of polypeptide by regulation of assembly
|
EP1870458B1
(en)
*
|
2005-03-31 |
2018-05-09 |
Chugai Seiyaku Kabushiki Kaisha |
sc(Fv)2 STRUCTURAL ISOMERS
|
EP2824183B1
(en)
*
|
2005-04-08 |
2020-07-29 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for producing bispecific antibodies
|
JP5085322B2
(ja)
|
2005-06-10 |
2012-11-28 |
中外製薬株式会社 |
sc(Fv)2を含有する医薬組成物
|
US8945543B2
(en)
*
|
2005-06-10 |
2015-02-03 |
Chugai Seiyaku Kabushiki Kaisha |
Stabilizer for protein preparation comprising meglumine and use thereof
|
KR101251157B1
(ko)
|
2005-07-25 |
2013-04-10 |
이머전트 프로덕트 디벨롭먼트 시애틀, 엘엘씨 |
Cd37-특이적 결합 분자 및 cd20-특이적 결합 분자를사용한 b-세포 감소
|
JP5474531B2
(ja)
*
|
2006-03-24 |
2014-04-16 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
操作されたヘテロ二量体タンパク質ドメイン
|
JP5624276B2
(ja)
|
2006-03-31 |
2014-11-12 |
中外製薬株式会社 |
抗体の血中動態を制御する方法
|
EP3345616A1
(en)
*
|
2006-03-31 |
2018-07-11 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody modification method for purifying bispecific antibody
|
RU2487888C2
(ru)
|
2006-06-12 |
2013-07-20 |
ЭМЕРДЖЕНТ ПРОДАКТ ДИВЕЛОПМЕНТ СИЭТЛ, ЭлЭлСи |
Одноцепочечные мультивалентные связывающие белки с эффекторной функцией
|
WO2008042236A2
(en)
|
2006-09-29 |
2008-04-10 |
Oncomed Pharmaceuticals, Inc. |
Compositions and methods for diagnosing and treating cancer
|
NZ614857A
(en)
|
2007-03-29 |
2015-04-24 |
Genmab As |
Bispecific antibodies and methods for production thereof
|
CA2688275A1
(en)
|
2007-05-31 |
2008-12-04 |
Genmab A/S |
Stable igg4 antibodies
|
ES2687808T3
(es)
|
2007-09-26 |
2018-10-29 |
Chugai Seiyaku Kabushiki Kaisha |
Región constante de anticuerpo modificado
|
US9096651B2
(en)
|
2007-09-26 |
2015-08-04 |
Chugai Seiyaku Kabushiki Kaisha |
Method of modifying isoelectric point of antibody via amino acid substitution in CDR
|
TW201634479A
(zh)
|
2007-12-05 |
2016-10-01 |
Chugai Pharmaceutical Co Ltd |
抗nr10抗體及其應用
|
US8242247B2
(en)
|
2007-12-21 |
2012-08-14 |
Hoffmann-La Roche Inc. |
Bivalent, bispecific antibodies
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
US8227577B2
(en)
*
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
PL2235064T3
(pl)
*
|
2008-01-07 |
2016-06-30 |
Amgen Inc |
Sposób otrzymywania cząsteczek przeciwciał z heterodimerycznymi fc z zastosowaniem kierujących efektów elektrostatycznych
|
TR201808046T4
(tr)
|
2008-04-11 |
2018-06-21 |
Chugai Pharmaceutical Co Ltd |
İki veya daha fazla sayıda antijen molekülüne tekrar tekrar bağlanabilen antijen bağlanma molekülü.
|
WO2009126944A1
(en)
|
2008-04-11 |
2009-10-15 |
Trubion Pharmaceuticals, Inc. |
Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
|
TWI440469B
(zh)
|
2008-09-26 |
2014-06-11 |
Chugai Pharmaceutical Co Ltd |
Improved antibody molecules
|
US8268314B2
(en)
|
2008-10-08 |
2012-09-18 |
Hoffmann-La Roche Inc. |
Bispecific anti-VEGF/anti-ANG-2 antibodies
|
TWI682995B
(zh)
|
2009-03-19 |
2020-01-21 |
日商中外製藥股份有限公司 |
抗體恆定區域改變體
|
EP2409991B1
(en)
|
2009-03-19 |
2017-05-03 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
CA2756244A1
(en)
|
2009-04-02 |
2010-10-07 |
Roche Glycart Ag |
Multispecific antibodies comprising full length antibodies and single chain fab fragments
|
WO2010112194A1
(en)
|
2009-04-02 |
2010-10-07 |
F. Hoffmann-La Roche Ag |
Antigen-binding polypeptides and multispecific antibodies comprising them
|
MX2011010168A
(es)
|
2009-04-07 |
2011-10-11 |
Roche Glycart Ag |
Anticuerpos biespecificos, trivalentes.
|
MX2011010166A
(es)
|
2009-04-07 |
2011-10-11 |
Roche Glycart Ag |
Anticuerpos biespecificos anti-erbb-3/anti-c-met.
|
SG175078A1
(en)
|
2009-04-07 |
2011-11-28 |
Roche Glycart Ag |
Bispecific anti-erbb-1/anti-c-met antibodies
|
CN102459346B
(zh)
*
|
2009-04-27 |
2016-10-26 |
昂考梅德药品有限公司 |
制造异源多聚体分子的方法
|
TW201100543A
(en)
*
|
2009-05-27 |
2011-01-01 |
Hoffmann La Roche |
Tri-or tetraspecific antibodies
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
US8703132B2
(en)
*
|
2009-06-18 |
2014-04-22 |
Hoffmann-La Roche, Inc. |
Bispecific, tetravalent antigen binding proteins
|
WO2011028952A1
(en)
*
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
RU2015153109A
(ru)
|
2009-09-16 |
2019-01-15 |
Дженентек, Инк. |
Содержащие суперспираль и/или привязку белковые комплексы и их применения
|
US10150808B2
(en)
|
2009-09-24 |
2018-12-11 |
Chugai Seiyaku Kabushiki Kaisha |
Modified antibody constant regions
|
MX2012003598A
(es)
|
2009-09-29 |
2012-04-20 |
Roche Glycart Ag |
Anticuerpos biespecificos agonistas de receptores de muerte.
|
PL3072526T3
(pl)
|
2009-10-16 |
2019-04-30 |
Oncomed Pharm Inc |
Kombinacja terapeutyczna i zastosowanie przeciwciał antagonistycznych względem DLL4 i środków antyhipertensyjnych
|
WO2011063348A1
(en)
*
|
2009-11-23 |
2011-05-26 |
Amgen Inc. |
Monomeric antibody fc
|
ES2777901T3
(es)
*
|
2009-12-25 |
2020-08-06 |
Chugai Pharmaceutical Co Ltd |
Método de modificación de polipéptidos para purificar multímeros polipeptídicos
|
KR101762467B1
(ko)
|
2010-01-29 |
2017-07-27 |
도레이 카부시키가이샤 |
폴리락트산계 수지 시트
|
WO2011108714A1
(ja)
|
2010-03-04 |
2011-09-09 |
中外製薬株式会社 |
抗体定常領域改変体
|
TWI426920B
(zh)
|
2010-03-26 |
2014-02-21 |
Hoffmann La Roche |
雙專一性、雙價抗-vegf/抗-ang-2抗體
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
AU2016219622A1
(en)
*
|
2010-04-20 |
2016-09-15 |
Genmab A/S |
Heterodimeric antibody FC-containing proteins and methods for production thereof
|
JP2019048814A
(ja)
*
|
2010-04-20 |
2019-03-28 |
ゲンマブ エー/エス |
ヘテロ二量体抗体Fc含有タンパク質およびその産生方法
|
AU2013203221B2
(en)
*
|
2010-04-20 |
2016-06-02 |
Genmab A/S |
Heterodimeric antibody FC-containing proteins and methods for production thereof
|
SG10201800757TA
(en)
*
|
2010-04-20 |
2018-02-27 |
Genmab As |
Heterodimeric antibody fc-containing proteins and methods for production thereof
|
JP6022444B2
(ja)
|
2010-05-14 |
2016-11-09 |
ライナット ニューロサイエンス コーポレイション |
ヘテロ二量体タンパク質ならびにそれを生産および精製するための方法
|
CA3051311A1
(en)
|
2010-05-27 |
2011-12-01 |
Genmab A/S |
Monoclonal antibodies against her2
|
WO2012016227A2
(en)
|
2010-07-29 |
2012-02-02 |
Xencor, Inc. |
Antibodies with modified isoelectric points
|
EP2609112B1
(en)
|
2010-08-24 |
2017-11-22 |
Roche Glycart AG |
Activatable bispecific antibodies
|
JP5758004B2
(ja)
|
2010-08-24 |
2015-08-05 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
ジスルフィドによって安定化されたFv断片を含む二重特異性抗体
|
US8551479B2
(en)
|
2010-09-10 |
2013-10-08 |
Oncomed Pharmaceuticals, Inc. |
Methods for treating melanoma
|
WO2012058768A1
(en)
|
2010-11-05 |
2012-05-10 |
Zymeworks Inc. |
Stable heterodimeric antibody design with mutations in the fc domain
|
DK2644698T3
(da)
|
2010-11-17 |
2018-01-22 |
Chugai Pharmaceutical Co Ltd |
Multispecifikt antigen-bindende molekyle med alternativ funktion til funktion af blodkoagulationsfaktor viii
|
EP2643353A1
(en)
|
2010-11-24 |
2013-10-02 |
Novartis AG |
Multispecific molecules
|
RU2642318C2
(ru)
|
2010-11-30 |
2018-01-24 |
Чугаи Сейяку Кабусики Кайся |
Антигенсвязывающая молекула, способная многократно связываться с множеством антигенных молекул
|
AR084053A1
(es)
|
2010-11-30 |
2013-04-17 |
Chugai Pharmaceutical Co Ltd |
Agente terapeutico que induce citotoxicidad
|
SG191153A1
(en)
|
2010-12-23 |
2013-07-31 |
Hoffmann La Roche |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
EP2679681B2
(en)
|
2011-02-25 |
2023-11-15 |
Chugai Seiyaku Kabushiki Kaisha |
FcgammaRIIB-specific FC antibody
|
KR101572338B1
(ko)
|
2011-02-28 |
2015-11-26 |
에프. 호프만-라 로슈 아게 |
1가 항원 결합 단백질
|
KR101638224B1
(ko)
|
2011-02-28 |
2016-07-08 |
에프. 호프만-라 로슈 아게 |
항원 결합 단백질
|
CA2828811C
(en)
|
2011-03-03 |
2021-09-21 |
Zymeworks Inc. |
Multivalent heteromultimer scaffold design and constructs
|
DK2698431T3
(da)
|
2011-03-30 |
2020-11-30 |
Chugai Pharmaceutical Co Ltd |
Opretholdelse af antigen-bindende molekyler i blodplasma og fremgangsmåde til modifikation af immunogenicitet
|
US20140170149A1
(en)
|
2011-04-20 |
2014-06-19 |
Genmab A/S |
Bispecific antibodies against her2 and cd3
|
EP2714738B1
(en)
|
2011-05-24 |
2018-10-10 |
Zyngenia, Inc. |
Multivalent and monovalent multispecific complexes and their uses
|
CN109517059B
(zh)
|
2011-06-30 |
2023-03-28 |
中外制药株式会社 |
异源二聚化多肽
|
UA117901C2
(uk)
|
2011-07-06 |
2018-10-25 |
Ґенмаб Б.В. |
Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування
|
KR101681818B1
(ko)
|
2011-08-23 |
2016-12-01 |
로슈 글리카트 아게 |
T 세포 활성화 항원 및 종양 항원에 대해 특이적인 이중특이적 항체 및 이의 사용 방법
|
GB201116092D0
(en)
|
2011-09-16 |
2011-11-02 |
Bioceros B V |
Antibodies and uses thereof
|
EP2758435A1
(en)
|
2011-09-23 |
2014-07-30 |
Roche Glycart AG |
Bispecific anti-egfr/anti igf-1r antibodies
|
HUE042192T2
(hu)
|
2011-09-23 |
2019-06-28 |
Oncomed Pharm Inc |
VEGF/DLL4-kötõ ágensek és alkalmazásaik
|
CA2791109C
(en)
|
2011-09-26 |
2021-02-16 |
Merus B.V. |
Generation of binding molecules
|
EP2762493B1
(en)
|
2011-09-30 |
2021-06-09 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities
|
TW201817744A
(zh)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
具有促進抗原清除之FcRn結合域的治療性抗原結合分子
|
KR102366029B1
(ko)
*
|
2011-09-30 |
2022-02-23 |
추가이 세이야쿠 가부시키가이샤 |
표적 항원에 대한 면역응답을 유도하는 항원 결합 분자
|
US10851178B2
(en)
|
2011-10-10 |
2020-12-01 |
Xencor, Inc. |
Heterodimeric human IgG1 polypeptides with isoelectric point modifications
|
HUE044633T2
(hu)
|
2011-10-27 |
2019-11-28 |
Genmab As |
Heterodimer fehérjék elõállítása
|
CN109111524B
(zh)
*
|
2011-10-31 |
2022-10-28 |
中外制药株式会社 |
控制了重链与轻链的缔合的抗原结合分子
|
CA2854233C
(en)
|
2011-11-04 |
2020-05-12 |
Zymeworks Inc. |
Stable heterodimeric antibody design with mutations in the fc domain
|
CN113416257A
(zh)
|
2011-11-30 |
2021-09-21 |
中外制药株式会社 |
包含进入细胞内以形成免疫复合体的搬运体(载体)的药物
|
EP2809682B1
(en)
|
2012-02-03 |
2020-04-08 |
F.Hoffmann-La Roche Ag |
Bispecific antibody molecules with antigen-transfected t-cells and their use in medicine
|
MX2014009565A
(es)
|
2012-02-10 |
2014-11-10 |
Genentech Inc |
Anticuerpos monocatenarios y otros heteromultimeros.
|
RU2736349C2
(ru)
|
2012-02-24 |
2020-11-16 |
Чугаи Сейяку Кабусики Кайся |
АНТИГЕНСВЯЗЫВАЮЩАЯ МОЛЕКУЛА ДЛЯ УСКОРЕНИЯ ИСЧЕЗНОВЕНИЯ АНТИГЕНА ЧЕРЕЗ FcγRIIB
|
BR112014024903A2
(pt)
|
2012-04-05 |
2017-07-11 |
Hoffmann La Roche |
anticorpos biespecíficos contra tweak humanao e il17 humana e seus usos
|
SG10201913376XA
(en)
|
2012-04-20 |
2020-02-27 |
Merus Nv |
Methods and means for the production of ig-like molecules
|
US9212227B2
(en)
|
2012-04-30 |
2015-12-15 |
Janssen Biotech, Inc. |
ST2L antibody antagonists for the treatment of ST2L-mediated inflammatory pulmonary conditions
|
DK2847231T3
(da)
|
2012-05-10 |
2019-10-14 |
Bioatla Llc |
Multispecifikke monoklonale antistoffer
|
MX2014014162A
(es)
|
2012-05-24 |
2015-02-04 |
Hoffmann La Roche |
Anticuerpos multiespecificos.
|
DK2857420T3
(da)
|
2012-05-30 |
2020-11-23 |
Chugai Pharmaceutical Co Ltd |
Målvævsspecifikt antigenbindende molekyle
|
EP2862875B1
(en)
*
|
2012-06-14 |
2023-09-06 |
Chugai Seiyaku Kabushiki Kaisha |
ANTIGEN-BINDING MOLECULE CONTAINING MODIFIED Fc REGION
|
US9499634B2
(en)
|
2012-06-25 |
2016-11-22 |
Zymeworks Inc. |
Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
|
JP6203838B2
(ja)
|
2012-06-27 |
2017-09-27 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
少なくとも2つの異なる結合実体を含む、テーラーメイドの高度に選択的かつ多重特異的なターゲティング実体を選択および作製するための方法、ならびにその使用
|
MX2014014804A
(es)
|
2012-06-27 |
2015-02-12 |
Hoffmann La Roche |
Metodo para la elaboracion de conjugados de la region fc de anticuerpos que comprenden por lo menos una entidad de union que se une especificamente a un objetivo y usos del mismo.
|
WO2014006118A1
(en)
|
2012-07-04 |
2014-01-09 |
F. Hoffmann-La Roche Ag |
Anti-theophylline antibodies and methods of use
|
RU2630296C2
(ru)
|
2012-07-04 |
2017-09-06 |
Ф. Хоффманн-Ля Рош Аг |
Антитела к биотину и способы их применения
|
SI2869848T1
(sl)
|
2012-07-04 |
2017-01-31 |
F. Hoffmann-La Roche Ag |
Kovalentno vezani konjugati antigen-protitelo
|
EP3632462A1
(en)
|
2012-07-06 |
2020-04-08 |
Genmab B.V. |
Dimeric protein with triple mutations
|
AU2013285355A1
(en)
|
2012-07-06 |
2015-01-29 |
Genmab B.V. |
Dimeric protein with triple mutations
|
WO2014012082A2
(en)
|
2012-07-13 |
2014-01-16 |
Zymeworks Inc. |
Multivalent heteromultimer scaffold design an constructs
|
MA37794B1
(fr)
|
2012-07-13 |
2017-07-31 |
Roche Glycart Ag |
Anticorps bispécifiques anti-vegf/anti-ang-2 et leur utilisation dans le cadre du traitement de pathologies vasculaires oculaires
|
CN102851338A
(zh)
*
|
2012-07-25 |
2013-01-02 |
苏州康宁杰瑞生物科技有限公司 |
利用电荷排斥作用制备同二聚体蛋白混合物的方法
|
BR112015001955A2
(pt)
|
2012-08-24 |
2017-11-07 |
Chugai Pharmaceutical Co Ltd |
variante de região fc específica de fcgamariib
|
KR101963231B1
(ko)
|
2012-09-11 |
2019-03-28 |
삼성전자주식회사 |
이중특이 항체의 제작을 위한 단백질 복합체 및 이를 이용한 이중특이 항체 제조 방법
|
ES2692951T3
(es)
|
2012-09-27 |
2018-12-05 |
Merus N.V. |
Anticuerpos IgG biespecíficos como acopladores de células T
|
AU2013326974B2
(en)
|
2012-10-03 |
2019-01-03 |
Zymeworks Bc Inc. |
Methods of quantitating heavy and light chain polypeptide pairs
|
BR112015007120A2
(pt)
|
2012-10-08 |
2017-12-12 |
Roche Glycart Ag |
anticorpo biespecífico, composição farmacêutica, uso, célula hospedeira e método de produção de um anticorpo
|
AU2013337811A1
(en)
|
2012-10-31 |
2015-05-14 |
Oncomed Pharmaceuticals, Inc. |
Methods and monitoring of treatment with a DLL4 antagonist
|
EP2915819B1
(en)
*
|
2012-11-05 |
2019-08-14 |
Zenyaku Kogyo Kabushikikaisha |
Antibody and antibody composition production method
|
UY35148A
(es)
|
2012-11-21 |
2014-05-30 |
Amgen Inc |
Immunoglobulinas heterodiméricas
|
NZ708352A
(en)
|
2012-11-21 |
2019-10-25 |
Janssen Biotech Inc |
Bispecific egfr/c-met antibodies
|
US9914785B2
(en)
|
2012-11-28 |
2018-03-13 |
Zymeworks Inc. |
Engineered immunoglobulin heavy chain-light chain pairs and uses thereof
|
BR112015012385A2
(pt)
|
2012-11-28 |
2019-08-27 |
Zymeworks Inc |
constructo de polipeptídeo de ligação de antígeno isolado, polinucleotídeo isolado ou conjunto de polinucleotídeos isolados, vetor ou conjunto de vetores, célula isolada, composição farmacêutica, uso do constructo, método para tratar um sujeito tendo uma doença ou distúrbio ou câncer ou doença vascular, método para inibir, reduzir ou bloquear um sinal dentro de uma célula, método para obter o constructo, método para preparar o constructo, meio de armazenamento legível por computador, método implementado por computador e método para produzir um constructo de polipeptídeo de ligação de antígeno bi-específico
|
US10766960B2
(en)
|
2012-12-27 |
2020-09-08 |
Chugai Seiyaku Kabushiki Kaisha |
Heterodimerized polypeptide
|
EA201500741A1
(ru)
|
2013-01-10 |
2016-01-29 |
Генмаб Б.В. |
ВАРИАНТЫ Fc-ОБЛАСТИ IGG1 ЧЕЛОВЕКА И ИХ ПРИМЕНЕНИЕ
|
US9605084B2
(en)
|
2013-03-15 |
2017-03-28 |
Xencor, Inc. |
Heterodimeric proteins
|
US10968276B2
(en)
|
2013-03-12 |
2021-04-06 |
Xencor, Inc. |
Optimized anti-CD3 variable regions
|
CN105051069B
(zh)
|
2013-01-14 |
2019-12-10 |
Xencor股份有限公司 |
新型异二聚体蛋白
|
US10487155B2
(en)
|
2013-01-14 |
2019-11-26 |
Xencor, Inc. |
Heterodimeric proteins
|
US10131710B2
(en)
|
2013-01-14 |
2018-11-20 |
Xencor, Inc. |
Optimized antibody variable regions
|
US9701759B2
(en)
|
2013-01-14 |
2017-07-11 |
Xencor, Inc. |
Heterodimeric proteins
|
US11053316B2
(en)
|
2013-01-14 |
2021-07-06 |
Xencor, Inc. |
Optimized antibody variable regions
|
US9738722B2
(en)
|
2013-01-15 |
2017-08-22 |
Xencor, Inc. |
Rapid clearance of antigen complexes using novel antibodies
|
WO2014122143A1
(en)
|
2013-02-05 |
2014-08-14 |
Engmab Ag |
Method for the selection of antibodies against bcma
|
EP2762497A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
EP2762496A1
(en)
|
2013-02-05 |
2014-08-06 |
EngMab AG |
Method for the selection of antibodies against BCMA
|
US10047163B2
(en)
|
2013-02-08 |
2018-08-14 |
Abbvie Stemcentrx Llc |
Multispecific constructs
|
JP6499087B2
(ja)
|
2013-02-26 |
2019-04-10 |
ロシュ グリクアート アーゲー |
二重特異性t細胞活性化抗原結合分子
|
CA2891493C
(en)
|
2013-02-26 |
2022-03-15 |
Roche Glycart Ag |
Bispecific t cell activating antigen binding molecules
|
KR101813708B1
(ko)
|
2013-03-13 |
2017-12-29 |
(주) 아이벤트러스 |
소수성 상호작용 부위내에 전기적 상호작용이 도입된 단백질 및 이의 제조방법
|
US9168300B2
(en)
|
2013-03-14 |
2015-10-27 |
Oncomed Pharmaceuticals, Inc. |
MET-binding agents and uses thereof
|
US10106624B2
(en)
|
2013-03-15 |
2018-10-23 |
Xencor, Inc. |
Heterodimeric proteins
|
KR20150128849A
(ko)
|
2013-03-15 |
2015-11-18 |
얀센 바이오테크 인코포레이티드 |
인터페론 알파 및 오메가 항체 길항제
|
US10858417B2
(en)
|
2013-03-15 |
2020-12-08 |
Xencor, Inc. |
Heterodimeric proteins
|
US10150800B2
(en)
|
2013-03-15 |
2018-12-11 |
Zyngenia, Inc. |
EGFR-binding modular recognition domains
|
US10519242B2
(en)
|
2013-03-15 |
2019-12-31 |
Xencor, Inc. |
Targeting regulatory T cells with heterodimeric proteins
|
EP2970486B1
(en)
|
2013-03-15 |
2018-05-16 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
WO2014150973A1
(en)
|
2013-03-15 |
2014-09-25 |
Eli Lilly And Company |
Methods for producing fabs and bi-specific antibodies
|
NZ712903A
(en)
|
2013-03-18 |
2018-07-27 |
Biocerox Prod Bv |
Humanized anti-cd134 (ox40) antibodies and uses thereof
|
MX2015014017A
(es)
|
2013-04-02 |
2016-02-10 |
Chugai Pharmaceutical Co Ltd |
Variante de la region fc.
|
UA118028C2
(uk)
|
2013-04-03 |
2018-11-12 |
Рош Глікарт Аг |
Біспецифічне антитіло, специфічне щодо fap і dr5, антитіло, специфічне щодо dr5, і спосіб їх застосування
|
EP2981286A4
(en)
*
|
2013-04-05 |
2016-08-24 |
Hoffmann La Roche |
ANTI-IL-4 ANTIBODIES AND BISPECIFIC ANTIBODIES AND USES THEREOF
|
EP2789630A1
(en)
|
2013-04-09 |
2014-10-15 |
EngMab AG |
Bispecific antibodies against CD3e and ROR1
|
EP3878866A1
(en)
|
2013-04-29 |
2021-09-15 |
F. Hoffmann-La Roche AG |
Fc-receptor binding modified asymmetric antibodies and methods of use
|
EP3327034A1
(en)
|
2013-04-29 |
2018-05-30 |
F. Hoffmann-La Roche AG |
Fcrn-binding abolished anti-igf-1r antibodies and their use in the treatment of vascular eye diseases
|
SG11201508911PA
(en)
|
2013-04-29 |
2015-11-27 |
Hoffmann La Roche |
Human fcrn-binding modified antibodies and methods of use
|
US9879081B2
(en)
|
2013-06-25 |
2018-01-30 |
Samsung Electronics Co., Ltd. |
Protein complex, bispecific antibody including the protein complex, and method of preparation thereof
|
US10465006B2
(en)
|
2013-07-05 |
2019-11-05 |
Genmab A/S |
Humanized or chimeric CD3 antibodies
|
AU2014325063B2
(en)
*
|
2013-09-27 |
2019-10-31 |
Chugai Seiyaku Kabushiki Kaisha |
Method for producing polypeptide heteromultimer
|
MX2016003617A
(es)
|
2013-09-30 |
2016-07-21 |
Chugai Pharmaceutical Co Ltd |
Metodo para producir molecula de enlace al antigeno usando fago auxiliar modificado.
|
CN105612182B
(zh)
|
2013-10-11 |
2019-12-10 |
豪夫迈·罗氏有限公司 |
多特异性结构域交换共有可变轻链抗体
|
PL3065774T3
(pl)
|
2013-11-06 |
2021-12-13 |
Janssen Biotech, Inc |
Przeciwciała anty-ccl17
|
BR112016010025A2
(pt)
|
2013-11-11 |
2017-12-05 |
Chugai Pharmaceutical Co Ltd |
molécula de ligação de antígeno contendo região variável de anticorpo modificado
|
US10961530B2
(en)
|
2013-12-04 |
2021-03-30 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecules, the antigen-binding activity of which varies according to the concentration of compounds, and libraries of said molecules
|
TWI701261B
(zh)
|
2013-12-17 |
2020-08-11 |
美商建南德克公司 |
抗cd3抗體及使用方法
|
CA2932958A1
(en)
|
2013-12-20 |
2015-06-25 |
F. Hoffmann-La Roche Ag |
Humanized anti-tau(ps422) antibodies and methods of use
|
EP3089759B1
(en)
|
2014-01-03 |
2018-12-05 |
F. Hoffmann-La Roche AG |
Covalently linked polypeptide toxin-antibody conjugates
|
KR102278979B1
(ko)
|
2014-01-03 |
2021-07-19 |
에프. 호프만-라 로슈 아게 |
공유적으로 연결된 헬리카-항-헬리카 항체 접합체 및 그의 용도
|
PL3089996T3
(pl)
|
2014-01-03 |
2021-12-13 |
F. Hoffmann-La Roche Ag |
Dwuswoiste przeciwciała przeciw haptenowi/przeciw receptorowi występującemu w barierze krew-mózg, ich kompleksy i ich zastosowanie jako przenośniki wahadłowe występujące w barierze krew-mózg
|
WO2015101588A1
(en)
|
2014-01-06 |
2015-07-09 |
F. Hoffmann-La Roche Ag |
Monovalent blood brain barrier shuttle modules
|
JP6786392B2
(ja)
|
2014-01-15 |
2020-11-18 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
FcRn結合特性が改変され、プロテインA結合特性が保持されているFc領域変異体
|
KR20160104636A
(ko)
|
2014-01-15 |
2016-09-05 |
에프. 호프만-라 로슈 아게 |
단백질 A-결합이 개선된 Fc-영역 변이체
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
US9732154B2
(en)
|
2014-02-28 |
2017-08-15 |
Janssen Biotech, Inc. |
Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia
|
US10844127B2
(en)
|
2014-02-28 |
2020-11-24 |
Merus N.V. |
Antibodies that bind EGFR and ErbB3
|
CA2941077A1
(en)
|
2014-02-28 |
2015-09-03 |
Merus N.V. |
Antibody that binds erbb-2 and erbb-3
|
WO2015138920A1
(en)
|
2014-03-14 |
2015-09-17 |
Novartis Ag |
Antibody molecules to lag-3 and uses thereof
|
US20170335281A1
(en)
|
2014-03-15 |
2017-11-23 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
UA119167C2
(uk)
|
2014-03-28 |
2019-05-10 |
Зенкор, Інк. |
Біспецифічне антитіло, яке зв'язується з cd38 та cd3
|
UA117289C2
(uk)
|
2014-04-02 |
2018-07-10 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифічне антитіло
|
KR102376287B1
(ko)
|
2014-04-02 |
2022-03-17 |
에프. 호프만-라 로슈 아게 |
다중특이적 항체 경쇄 잘못짝짓기의 검출 방법
|
ES2900898T3
(es)
|
2014-04-07 |
2022-03-18 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos biespecíficos inmunoactivadores
|
EP3137506B1
(en)
|
2014-05-02 |
2023-08-30 |
Momenta Pharmaceuticals, Inc. |
Compositions and methods related to engineered fc constructs
|
AU2015260230A1
(en)
|
2014-05-13 |
2016-11-17 |
Chugai Seiyaku Kabushiki Kaisha |
T cell-redirected antigen-binding molecule for cells having immunosuppression function
|
EA201692476A1
(ru)
|
2014-05-28 |
2017-07-31 |
Займворкс Инк. |
Модифицированные антигенсвязывающие полипептидные конструкции и их применение
|
US9416172B2
(en)
|
2014-06-03 |
2016-08-16 |
Xbiotech, Inc. |
Compositions and methods for treating and preventing Staphylococcus aureus infections
|
TWI713453B
(zh)
|
2014-06-23 |
2020-12-21 |
美商健生生物科技公司 |
干擾素α及ω抗體拮抗劑
|
AR100978A1
(es)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
|
CA2947504A1
(en)
|
2014-06-26 |
2015-12-30 |
F. Hoffmann-La Roche Ag |
Anti-brdu antibodies and methods of use
|
MX370807B
(es)
|
2014-07-11 |
2020-01-08 |
Genmab As |
Anticuerpos que se unen a axl.
|
AU2015292755B2
(en)
|
2014-07-21 |
2020-11-12 |
Novartis Ag |
Treatment of cancer using a CD33 chimeric antigen receptor
|
WO2016014530A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
AU2015292744C1
(en)
|
2014-07-21 |
2021-01-21 |
Novartis Ag |
Treatment of cancer using humanized anti-BCMA chimeric antigen receptor
|
ES2781175T3
(es)
|
2014-07-31 |
2020-08-31 |
Novartis Ag |
Subconjunto optimizado de células T que contienen un receptor de antígeno quimérico
|
EP2982692A1
(en)
|
2014-08-04 |
2016-02-10 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
ES2979976T3
(es)
|
2014-08-04 |
2024-09-27 |
Hoffmann La Roche |
Moléculas de unión a antígeno activadoras de linfocitos T biespecíficas
|
WO2016025880A1
(en)
|
2014-08-14 |
2016-02-18 |
Novartis Ag |
Treatment of cancer using gfr alpha-4 chimeric antigen receptor
|
TWI719946B
(zh)
|
2014-08-19 |
2021-03-01 |
瑞士商諾華公司 |
使用cd123嵌合抗原受體治療癌症
|
PT3189081T
(pt)
|
2014-09-05 |
2020-05-25 |
Janssen Pharmaceutica Nv |
Agentes de ligação a cd123 e seus usos
|
AU2015315396B2
(en)
|
2014-09-09 |
2020-10-08 |
Janssen Biotech, Inc. |
Combination therapies with anti-CD38 antibodies
|
SG11201701627PA
(en)
|
2014-09-12 |
2017-03-30 |
Genentech Inc |
Anti-cll-1 antibodies and immunoconjugates
|
WO2016044224A1
(en)
|
2014-09-15 |
2016-03-24 |
Amgen Inc. |
Bi-specific anti-cgrp receptor/pac1 receptor antigen binding proteins and uses thereof
|
KR102590396B1
(ko)
|
2014-09-17 |
2023-10-19 |
노파르티스 아게 |
입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
TWI700300B
(zh)
|
2014-09-26 |
2020-08-01 |
日商中外製藥股份有限公司 |
中和具有第viii凝血因子(fviii)機能替代活性的物質之抗體
|
TWI701435B
(zh)
|
2014-09-26 |
2020-08-11 |
日商中外製藥股份有限公司 |
測定fviii的反應性之方法
|
US11952421B2
(en)
|
2014-10-09 |
2024-04-09 |
Bristol-Myers Squibb Company |
Bispecific antibodies against CD3EPSILON and ROR1
|
TWI716362B
(zh)
|
2014-10-14 |
2021-01-21 |
瑞士商諾華公司 |
針對pd-l1之抗體分子及其用途
|
CA2966042A1
(en)
|
2014-10-31 |
2016-05-06 |
Oncomed Pharmaceuticals, Inc. |
Combination therapy for treatment of disease
|
KR20170076697A
(ko)
|
2014-11-06 |
2017-07-04 |
에프. 호프만-라 로슈 아게 |
개질된 FCRN-결합 특성 및 단백질 A-결합 특성을 가진 Fc-영역 변이체
|
AR102521A1
(es)
|
2014-11-06 |
2017-03-08 |
Hoffmann La Roche |
Variantes de región fc con unión de fcrn modificada y métodos de utilización
|
TWI831044B
(zh)
|
2014-11-11 |
2024-02-01 |
日商中外製藥股份有限公司 |
抗原結合分子、包含抗原結合分子的醫藥組合物以及製造及選擇抗原結合分子之方法
|
KR20170087486A
(ko)
|
2014-11-20 |
2017-07-28 |
에프. 호프만-라 로슈 아게 |
일반 경쇄 및 이의 사용 방법
|
MX2017006610A
(es)
|
2014-11-20 |
2017-09-29 |
Hoffmann La Roche |
Terapia combinada de moleculas de union a antigeno biespecificas activadoras de celulas t y antagonistas de union de eje de pd-1.
|
EP3023437A1
(en)
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
US10259887B2
(en)
|
2014-11-26 |
2019-04-16 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and tumor antigens
|
HUE055115T2
(hu)
|
2014-11-26 |
2021-10-28 |
Xencor Inc |
CD3-at és CD20-at kötõ heterodimer antitestek
|
SG11201704274QA
(en)
|
2014-11-26 |
2017-06-29 |
Xencor Inc |
Heterodimeric antibodies that bind cd3 and cd38
|
PL3227332T3
(pl)
|
2014-12-03 |
2020-06-15 |
F. Hoffmann-La Roche Ag |
Wielospecyficzne przeciwciała
|
WO2016090034A2
(en)
|
2014-12-03 |
2016-06-09 |
Novartis Ag |
Methods for b cell preconditioning in car therapy
|
HUE056489T2
(hu)
|
2014-12-19 |
2022-02-28 |
Chugai Pharmaceutical Co Ltd |
Anti-C5 antitestek és alkalmazási eljárások
|
DK3233907T3
(da)
|
2014-12-19 |
2021-06-07 |
Genmab As |
Bispecifikke heterodimeriske proteiner hos gnavere
|
MY181199A
(en)
|
2014-12-19 |
2020-12-21 |
Chugai Pharmaceutical Co Ltd |
Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
|
WO2016105450A2
(en)
|
2014-12-22 |
2016-06-30 |
Xencor, Inc. |
Trispecific antibodies
|
MA41375A
(fr)
|
2015-01-22 |
2017-11-28 |
Lilly Co Eli |
Anticorps igg bispécifiques et leurs procédés de préparation
|
EA201791754A1
(ru)
|
2015-02-05 |
2019-01-31 |
Чугаи Сейяку Кабусики Кайся |
АНТИТЕЛА, СОДЕРЖАЩИЕ ЗАВИСЯЩИЙ ОТ КОНЦЕНТРАЦИИ ИОНОВ АНТИГЕНСВЯЗЫВАЮЩИЙ ДОМЕН, ВАРИАНТЫ Fc-ОБЛАСТИ, IL-8-СВЯЗЫВАЮЩИЕ АНТИТЕЛА И ИХ ПРИМЕНЕНИЯ
|
JP6130983B2
(ja)
|
2015-02-27 |
2017-05-17 |
中外製薬株式会社 |
Il−6関連疾患治療用組成物
|
WO2016141387A1
(en)
|
2015-03-05 |
2016-09-09 |
Xencor, Inc. |
Modulation of t cells with bispecific antibodies and fc fusions
|
WO2016159213A1
(ja)
*
|
2015-04-01 |
2016-10-06 |
中外製薬株式会社 |
ポリペプチド異種多量体の製造方法
|
DK3280729T3
(da)
|
2015-04-08 |
2022-07-25 |
Novartis Ag |
Cd20-behandlinger, cd22-behandlinger og kombinationsbehandlinger med en cd19-kimær antigenreceptor (car)-udtrykkende celle
|
CN107454906B
(zh)
|
2015-04-17 |
2022-05-27 |
豪夫迈·罗氏有限公司 |
使用凝固因子和多特异性抗体的联合治疗
|
WO2016172583A1
(en)
|
2015-04-23 |
2016-10-27 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
EP3291836A4
(en)
|
2015-05-06 |
2018-11-14 |
Janssen Biotech, Inc. |
Prostate specific membrane antigen (psma) bispecific binding agents and uses thereof
|
JP6827426B2
(ja)
|
2015-05-20 |
2021-02-10 |
ヤンセン バイオテツク,インコーポレーテツド |
軽鎖アミロイドーシス及びその他のcd38陽性血液悪性疾患の治療のための抗cd38抗体
|
KR20180023952A
(ko)
|
2015-06-16 |
2018-03-07 |
제넨테크, 인크. |
FcRH5에 대한 인간화 및 친화도 성숙 항체 및 사용방법
|
JP6996983B2
(ja)
|
2015-06-16 |
2022-02-21 |
ジェネンテック, インコーポレイテッド |
抗cll-1抗体及び使用方法
|
UA125115C2
(uk)
|
2015-06-22 |
2022-01-12 |
Янссен Байотек, Інк. |
Спосіб лікування суб'єкта, який має множинну мієлому (мм)
|
CN113929779A
(zh)
|
2015-06-24 |
2022-01-14 |
豪夫迈·罗氏有限公司 |
人源化的抗-Tau(pS422)抗体和使用方法
|
PL3313441T3
(pl)
|
2015-06-24 |
2024-08-19 |
Janssen Biotech, Inc. |
Immunomodulacja i leczenie guzów litych przeciwciałami swoiście wiążącymi cd38
|
EP3319996B1
(en)
|
2015-07-09 |
2024-01-03 |
Genmab A/S |
Bispecific and multispecific antibodies and method for isolation of such
|
KR20180033523A
(ko)
|
2015-07-10 |
2018-04-03 |
젠맵 에이/에스 |
암 치료를 위한 axl-특이적 항체-약물 접합체
|
HUE042039T2
(hu)
|
2015-07-10 |
2019-06-28 |
Merus Nv |
Humán CD3 kötõ antitest
|
CN114989302A
(zh)
|
2015-07-15 |
2022-09-02 |
根马布股份公司 |
人源化或嵌合cd3抗体
|
PT3317301T
(pt)
|
2015-07-29 |
2021-07-09 |
Novartis Ag |
Terapias de associação compreendendo moléculas de anticorpo contra lag-3
|
CN114272371A
(zh)
|
2015-07-29 |
2022-04-05 |
诺华股份有限公司 |
包含抗pd-1抗体分子的联合疗法
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
AU2016302881B2
(en)
|
2015-08-03 |
2022-09-15 |
Bristol-Myers Squibb Company |
Monoclonal antibodies against BCMA
|
MX2018001522A
(es)
|
2015-08-05 |
2018-03-15 |
Janssen Biotech Inc |
Anticuerpos anti-cd154 y metodos de uso de estos.
|
TWI811023B
(zh)
|
2015-08-17 |
2023-08-01 |
美商健生生物科技公司 |
抗bcma抗體,結合bcma及cd3之雙特異性抗原結合分子及其用途
|
WO2017053469A2
(en)
|
2015-09-21 |
2017-03-30 |
Aptevo Research And Development Llc |
Cd3 binding polypeptides
|
EP3353204B1
(en)
|
2015-09-23 |
2023-10-18 |
Mereo BioPharma 5, Inc. |
Bi-specific anti-vegf/dll4 antibody for use in treating platinum-resistant ovarian cancer
|
BR112018006251A2
(pt)
|
2015-09-30 |
2018-10-16 |
Janssen Biotech Inc |
anticorpos antagonistas que se ligam especificamente a cd40 humano e métodos de uso
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
WO2017055393A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xtim-3 bispecific t cell activating antigen binding molecules
|
CR20180161A
(es)
|
2015-10-02 |
2018-05-25 |
Hoffmann La Roche |
Anticuerpos biespecíficos para pd1 y tim3
|
US20170096485A1
(en)
|
2015-10-02 |
2017-04-06 |
Hoffmann-La Roche Inc. |
Bispecific t cell activating antigen binding molecules
|
EP3356821B1
(en)
|
2015-10-02 |
2019-10-23 |
H. Hoffnabb-La Roche Ag |
Cellular based fret assay for the determination of simultaneous binding
|
US20180282410A1
(en)
|
2015-10-02 |
2018-10-04 |
Hoffmann-La Roche Inc. |
Anti-cd3xrob04 bispecific t cell activating antigen binding molecules
|
CN108026177B
(zh)
|
2015-10-02 |
2021-11-26 |
豪夫迈·罗氏有限公司 |
双特异性抗cd19xcd3 t细胞活化性抗原结合分子
|
CN107949574A
(zh)
|
2015-10-02 |
2018-04-20 |
豪夫迈·罗氏有限公司 |
双特异性t细胞活化性抗原结合分子
|
WO2017055392A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xcd44v6 bispecific t cell activating antigen binding molecules
|
EP3150637A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Multispecific antibodies
|
EP3150636A1
(en)
|
2015-10-02 |
2017-04-05 |
F. Hoffmann-La Roche AG |
Tetravalent multispecific antibodies
|
WO2017055385A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Anti-cd3xgd2 bispecific t cell activating antigen binding molecules
|
AR106201A1
(es)
|
2015-10-02 |
2017-12-20 |
Hoffmann La Roche |
Moléculas biespecíficas de unión a antígeno activadoras de células t
|
CN108283001B
(zh)
|
2015-10-08 |
2022-08-19 |
酵活有限公司 |
包含κ和λ轻链的抗原结合多肽构建体及其用途
|
RU2767209C2
(ru)
|
2015-10-23 |
2022-03-16 |
Еурека Терапьютикс, Инк. |
Химерные конструкции антитело/т-клеточный рецептор и их применения
|
ES2865482T3
(es)
|
2015-10-23 |
2021-10-15 |
Merus Nv |
Moléculas de unión que inhiben el crecimiento del cáncer
|
CN114891102A
(zh)
|
2015-10-29 |
2022-08-12 |
豪夫迈·罗氏有限公司 |
抗变体Fc区抗体及使用方法
|
MA43164A
(fr)
|
2015-11-02 |
2018-09-12 |
Janssen Pharmaceutica Nv |
Anticorps anti-il1rap, molécules bispécifiques de liaison à un antigène liant il1rap et cd3 et leurs utilisations
|
CR20180234A
(es)
|
2015-11-03 |
2018-09-11 |
Janssen Biotech Inc |
Anticuerpos que se unen especificamente a pd-1 y sus usos
|
PT3370770T
(pt)
|
2015-11-03 |
2021-02-22 |
Janssen Biotech Inc |
Formulações subcutâneas de anticorpos anti-cd38 e suas utilizações
|
JP6931329B2
(ja)
|
2015-11-18 |
2021-09-01 |
中外製薬株式会社 |
免疫抑制機能を有する細胞に対するt細胞リダイレクト抗原結合分子を用いた併用療法
|
WO2017086419A1
(ja)
|
2015-11-18 |
2017-05-26 |
中外製薬株式会社 |
液性免疫応答の増強方法
|
CN108699136B
(zh)
|
2015-12-07 |
2022-03-18 |
Xencor股份有限公司 |
结合cd3和psma的异二聚抗体
|
JP7325186B2
(ja)
|
2015-12-09 |
2023-08-14 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
抗薬物抗体の形成を減少させるためのii型抗cd20抗体
|
EP3178848A1
(en)
|
2015-12-09 |
2017-06-14 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies
|
CR20180365A
(es)
|
2015-12-16 |
2018-09-28 |
Amgen Inc |
PROTEÍNAS DE UNIÓN AL ANTÍGENO BISPECÍFICO DE ANTI-TL1A/ANTI-TNF-a Y SUS USOS
|
WO2017106684A2
(en)
|
2015-12-17 |
2017-06-22 |
Janssen Biotech, Inc. |
Antibodies specifically binding hla-dr and their uses
|
AU2016369623A1
(en)
|
2015-12-17 |
2018-06-28 |
Novartis Ag |
Combination of c-Met inhibitor with antibody molecule to PD-1 and uses thereof
|
AU2016369537B2
(en)
|
2015-12-17 |
2024-03-14 |
Novartis Ag |
Antibody molecules to PD-1 and uses thereof
|
US11359009B2
(en)
|
2015-12-25 |
2022-06-14 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-myostatin antibodies and methods of use
|
EP3395835B1
(en)
|
2015-12-25 |
2021-02-03 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody having enhanced activity, and method for modifying same
|
US11649262B2
(en)
|
2015-12-28 |
2023-05-16 |
Chugai Seiyaku Kabushiki Kaisha |
Method for promoting efficiency of purification of Fc region-containing polypeptide
|
CN106661117B
(zh)
*
|
2015-12-30 |
2020-11-17 |
深圳先进技术研究院 |
IgG杂合型抗TNFα和IL-17A双特异性抗体
|
AR107303A1
(es)
|
2016-01-08 |
2018-04-18 |
Hoffmann La Roche |
Métodos de tratamiento de cánceres positivos para ace utilizando antagonistas de unión a eje pd-1 y anticuerpos biespecíficos anti-ace / anti-cd3, uso, composición, kit
|
ES2847155T3
(es)
|
2016-01-21 |
2021-08-02 |
Novartis Ag |
Moléculas multiespecíficas que fijan como objetivo CLL-1
|
CA3016287A1
(en)
|
2016-03-04 |
2017-09-08 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
|
TW201735947A
(zh)
|
2016-03-14 |
2017-10-16 |
Chugai Pharmaceutical Co Ltd |
用於癌之治療的細胞傷害誘導治療劑
|
JP7082604B2
(ja)
|
2016-03-21 |
2022-06-08 |
マレンゴ・セラピューティクス,インコーポレーテッド |
多重特異性および多機能性分子ならびにその使用
|
PL3433280T3
(pl)
|
2016-03-22 |
2023-07-31 |
F. Hoffmann-La Roche Ag |
Dwuswoiste cząsteczki limfocytów T aktywowane przez proteazy
|
WO2017165683A1
(en)
|
2016-03-23 |
2017-09-28 |
Novartis Ag |
Cell secreted minibodies and uses thereof
|
KR20230051601A
(ko)
|
2016-04-15 |
2023-04-18 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
Icos 리간드 변이체 면역조절 단백질 및 그의 용도
|
MA43552A
(fr)
|
2016-04-15 |
2018-11-07 |
Alpine Immune Sciences Inc |
Protéines immunomodulatrices à variants de cd80 et leurs utilisations
|
CA3021027A1
(en)
|
2016-04-15 |
2017-10-19 |
Novartis Ag |
Compositions and methods for selective expression of chimeric antigen receptors
|
BR112018071283A2
(pt)
|
2016-04-20 |
2019-02-12 |
Regeneron Pharma |
célula, conjunto de vetores para expressar uma proteína de ligação a antígeno biespecífica em uma célula, conjunto de vetores, método, e, método para produção de uma proteína de ligação a antígeno.
|
AR108295A1
(es)
|
2016-04-20 |
2018-08-08 |
Regeneron Pharma |
Composiciones y métodos para preparar anticuerpos basados en el uso de un locus mejorador de expresión
|
EP3452502B1
(en)
|
2016-05-02 |
2021-03-03 |
H. Hoffnabb-La Roche Ag |
The contorsbody - a single chain target binder
|
SG10202011624SA
(en)
|
2016-05-23 |
2021-01-28 |
Momenta Pharmaceuticals Inc |
Compositions and methods related to engineered fc constructs
|
EP3252078A1
(en)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody and anti-cd20/cd3 bispecific antibody for treatment of cancer
|
EP3464375A2
(en)
|
2016-06-02 |
2019-04-10 |
Novartis AG |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
AU2018276419A1
(en)
|
2016-06-02 |
2019-10-17 |
F. Hoffmann-La Roche Ag |
Type II anti-CD20 antibody and anti-CD20/CD3 bispecific antibody for treatment of cancer
|
EP4257613A3
(en)
|
2016-06-14 |
2023-12-13 |
Xencor, Inc. |
Bispecific checkpoint inhibitor antibodies
|
CN109715663B
(zh)
|
2016-06-28 |
2022-11-25 |
Xencor股份有限公司 |
结合生长抑素受体2的异源二聚抗体
|
US20190233533A1
(en)
|
2016-06-28 |
2019-08-01 |
Umc Utrecht Holding B.V. |
Treatment Of IgE-Mediated Diseases With Antibodies That Specifically Bind CD38
|
JP6983824B2
(ja)
|
2016-07-04 |
2021-12-17 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
新規抗体フォーマット
|
CA3030636A1
(en)
|
2016-07-14 |
2018-01-18 |
Genmab A/S |
Multispecific antibodies against cd40 and cd137
|
AU2017295886C1
(en)
|
2016-07-15 |
2024-05-16 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
TWI781108B
(zh)
|
2016-07-20 |
2022-10-21 |
比利時商健生藥品公司 |
抗gprc5d抗體、結合gprc5d與cd3之雙特異性抗原結合分子及其用途
|
WO2018022946A1
(en)
|
2016-07-28 |
2018-02-01 |
Alpine Immune Sciences, Inc. |
Cd155 variant immunomodulatory proteins and uses thereof
|
CN110214150A
(zh)
|
2016-07-28 |
2019-09-06 |
诺华股份有限公司 |
嵌合抗原受体和pd-1抑制剂的组合疗法
|
WO2018022945A1
(en)
|
2016-07-28 |
2018-02-01 |
Alpine Immune Sciences, Inc. |
Cd112 variant immunomodulatory proteins and uses thereof
|
KR20190036551A
(ko)
|
2016-08-01 |
2019-04-04 |
노파르티스 아게 |
Pro-m2 대식세포 분자의 억제제를 병용하는, 키메라 항원 수용체를 이용한 암의 치료
|
KR102538749B1
(ko)
|
2016-08-05 |
2023-06-01 |
추가이 세이야쿠 가부시키가이샤 |
Il-8 관련 질환의 치료용 또는 예방용 조성물
|
JP7178342B2
(ja)
|
2016-08-12 |
2022-11-25 |
ヤンセン バイオテツク,インコーポレーテツド |
アゴニズム及びエフェクター機能が増強した改変抗体、及び他のFcドメイン含有分子
|
EP3497126A4
(en)
|
2016-08-12 |
2020-04-08 |
Janssen Biotech, Inc. |
ANTIBODIES OF FC MODIFIED ANTI-TNFR SUPERFAMILY HAVING IMPROVED AGONIST ACTIVITY AND METHODS OF USE THEREOF
|
US10793632B2
(en)
|
2016-08-30 |
2020-10-06 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
CA3035327A1
(en)
|
2016-09-06 |
2018-03-15 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of using a bispecific antibody that recognizes coagulation factor ix and/or activated coagulation factor ix and coagulation factor x and/or activated coagulation factor x
|
EP3519820B1
(en)
|
2016-09-30 |
2020-12-09 |
H. Hoffnabb-La Roche Ag |
Spr-based dual-binding assay for the functional analysis of multispecific molecules
|
JP7022123B2
(ja)
|
2016-09-30 |
2022-02-17 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
Cd3に対する二重特異性抗体
|
BR112019006781A2
(pt)
|
2016-10-07 |
2019-07-30 |
Novartis Ag |
receptores de antígeno quiméricos para o tratamento de câncer
|
SG11201903302UA
(en)
|
2016-10-14 |
2019-05-30 |
Xencor Inc |
Bispecific heterodimeric fusion proteins containing il-15/il-15ralpha fc-fusion proteins and pd-1 antibody fragments
|
JOP20190095A1
(ar)
|
2016-10-27 |
2019-04-28 |
Janssen Pharmaceutica Nv |
مركبات ببتيد تيروسين-تيروسين الحلقية كمعدلات لمستقبلات الببتيد العصبي y
|
CA3041988A1
(en)
|
2016-11-01 |
2018-05-11 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
AU2017353427A1
(en)
|
2016-11-02 |
2019-05-16 |
Bristol-Myers Squibb Company |
Bispecific antibody against BCMA and CD3 and an immunological drug for combined use in treating multiple myeloma
|
KR20190074300A
(ko)
|
2016-11-15 |
2019-06-27 |
제넨테크, 인크. |
항-cd20/항-cd3 이중특이적 항체에 의한 치료를 위한 투약
|
TW201829463A
(zh)
|
2016-11-18 |
2018-08-16 |
瑞士商赫孚孟拉羅股份公司 |
抗hla-g抗體及其用途
|
TN2019000164A1
(en)
|
2016-11-23 |
2020-10-05 |
Bioverativ Therapeutics Inc |
Mono- and bispecific antibodies binding to coagulation factor ix and coagulation factor x
|
CA3045323A1
(en)
|
2016-12-02 |
2018-06-07 |
Juno Therapeutics, Inc. |
Engineered b cells and related compositions and methods
|
US11129906B1
(en)
|
2016-12-07 |
2021-09-28 |
David Gordon Bermudes |
Chimeric protein toxins for expression by therapeutic bacteria
|
WO2018122053A1
(en)
|
2016-12-29 |
2018-07-05 |
F. Hoffmann-La Roche Ag |
Anti-angiopoietin-2 antibody formulation
|
SG11201906139VA
(en)
|
2017-01-06 |
2019-08-27 |
Momenta Pharmaceuticals Inc |
Compositions and methods related to engineered fc constructs
|
ES2912408T3
(es)
|
2017-01-26 |
2022-05-25 |
Novartis Ag |
Composiciones de CD28 y métodos para terapia con receptores quiméricos para antígenos
|
WO2018146317A1
(en)
|
2017-02-10 |
2018-08-16 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
WO2018151820A1
(en)
|
2017-02-16 |
2018-08-23 |
Elstar Therapeutics, Inc. |
Multifunctional molecules comprising a trimeric ligand and uses thereof
|
WO2018155611A1
(ja)
|
2017-02-24 |
2018-08-30 |
中外製薬株式会社 |
薬学的組成物、抗原結合分子、治療方法、およびスクリーニング方法
|
CN118063619A
(zh)
|
2017-03-02 |
2024-05-24 |
诺华股份有限公司 |
工程化的异源二聚体蛋白质
|
CN110573524B
(zh)
|
2017-03-09 |
2023-07-18 |
健玛保 |
针对pd-l1的抗体
|
CA3052357A1
(en)
|
2017-03-10 |
2018-09-13 |
F. Hoffmann-La Roche Ag |
Method for producing multispecific antibodies
|
CA3053812A1
(en)
|
2017-03-16 |
2018-09-20 |
Alpine Immune Sciences, Inc. |
Pd-l2 variant immunomodulatory proteins and uses thereof
|
CA3054068A1
(en)
|
2017-03-16 |
2018-09-20 |
Alpine Immune Sciences, Inc. |
Cd80 variant immunomodulatory proteins and uses thereof
|
ES2963638T3
(es)
|
2017-03-16 |
2024-04-01 |
Alpine Immune Sciences Inc |
Proteínas inmunomoduladoras de variantes de PD-L1 y usos de las mismas
|
WO2018181870A1
(ja)
|
2017-03-31 |
2018-10-04 |
公立大学法人奈良県立医科大学 |
血液凝固第viii因子の機能を代替する多重特異性抗原結合分子を含有する、血液凝固第ix因子異常症の予防および/または治療に用いられる医薬組成物
|
AU2018246873B2
(en)
|
2017-03-31 |
2021-05-06 |
Merus N.V. |
ErbB-2 and ErbB3 binding bispecific antibodies for use in the treatment f cells that have an NRG1 fusion gene
|
MX2019011520A
(es)
|
2017-03-31 |
2020-08-03 |
Genmab Holding B V |
Anticuerpos anti antigeno leucocito 37 (cd37) biespecificos, anticuerpos anti antigeno leucocito 37 (cd37) monoclonales y metodos de uso de los mismos.
|
MX2019011858A
(es)
|
2017-04-03 |
2019-11-21 |
Oncologie Inc |
Metodos para tratar el cancer con anticuerpos dirigidos a ps con agentes inmunooncologicos.
|
WO2018184965A1
(en)
|
2017-04-03 |
2018-10-11 |
F. Hoffmann-La Roche Ag |
Immunoconjugates of il-2 with an anti-pd-1 and tim-3 bispecific antibody
|
SG11201909205YA
(en)
|
2017-04-03 |
2019-11-28 |
Hoffmann La Roche |
Immunoconjugates of an anti-pd-1 antibody with a mutant il-2 or with il-15
|
SG11201909218RA
(en)
|
2017-04-03 |
2019-11-28 |
Hoffmann La Roche |
Antibodies binding to steap-1
|
WO2018189220A1
(en)
|
2017-04-13 |
2018-10-18 |
F. Hoffmann-La Roche Ag |
An interleukin-2 immunoconjugate, a cd40 agonist, and optionally a pd-1 axis binding antagonist for use in methods of treating cancer
|
JP7538601B2
(ja)
|
2017-04-26 |
2024-08-22 |
ユーリカ セラピューティックス, インコーポレイテッド |
キメラ活性化受容体及びキメラ刺激受容体を発現する細胞並びにその使用
|
WO2018201051A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
US11851486B2
(en)
|
2017-05-02 |
2023-12-26 |
National Center Of Neurology And Psychiatry |
Method for predicting and evaluating therapeutic effect in diseases related to IL-6 and neutrophils
|
US20210246227A1
(en)
|
2017-05-31 |
2021-08-12 |
Elstar Therapeutics, Inc. |
Multispecific molecules that bind to myeloproliferative leukemia (mpl) protein and uses thereof
|
MX2019014577A
(es)
|
2017-06-05 |
2020-07-29 |
Janssen Biotech Inc |
Anticuerpos que se unen especificamente a pd-1 y metodos de uso.
|
US11149094B2
(en)
|
2017-06-05 |
2021-10-19 |
Janssen Biotech, Inc. |
Engineered multispecific antibodies and other multimeric proteins with asymmetrical CH2-CH3 region mutations
|
WO2018224609A1
(en)
|
2017-06-07 |
2018-12-13 |
Genmab B.V. |
Therapeutic antibodies based on mutated igg hexamers
|
UY37758A
(es)
|
2017-06-12 |
2019-01-31 |
Novartis Ag |
Método de fabricación de anticuerpos biespecíficos, anticuerpos biespecíficos y uso terapéutico de dichos anticuerpos
|
MA49457A
(fr)
|
2017-06-22 |
2020-04-29 |
Novartis Ag |
Molécules d'anticorps se liant à cd73 et leurs utilisations
|
GB201709970D0
(en)
|
2017-06-22 |
2017-08-09 |
Kymab Ltd |
Bispecific antigen-binding molecules
|
CN111050791A
(zh)
|
2017-06-27 |
2020-04-21 |
诺华股份有限公司 |
用于抗tim-3抗体的给药方案及其用途
|
US11084863B2
(en)
|
2017-06-30 |
2021-08-10 |
Xencor, Inc. |
Targeted heterodimeric Fc fusion proteins containing IL-15 IL-15alpha and antigen binding domains
|
AR112603A1
(es)
|
2017-07-10 |
2019-11-20 |
Lilly Co Eli |
Anticuerpos biespecíficos inhibidores de punto de control
|
KR102714165B1
(ko)
|
2017-07-11 |
2024-10-10 |
콤파스 테라퓨틱스 엘엘씨 |
인간 cd137에 결합하는 작동자 항체 및 이의 용도
|
US20200172617A1
(en)
|
2017-07-20 |
2020-06-04 |
Novartis Ag |
Dosage regimens of anti-lag-3 antibodies and uses thereof
|
JP7290013B2
(ja)
|
2017-08-04 |
2023-06-13 |
ジェンマブ エー/エス |
Pd-l1およびcd137に結合する結合物質ならびにその使用
|
CN118562014A
(zh)
|
2017-08-09 |
2024-08-30 |
美勒斯公司 |
结合EGFR和cMET的抗体
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
AU2018338859A1
(en)
|
2017-09-29 |
2020-02-06 |
Chugai Seiyaku Kabushiki Kaisha |
Multispecific antigen-binding molecule having blood coagulation factor VIII (FVIII) cofactor function-substituting activity, and pharmaceutical formulation containing said molecule as active ingredient
|
KR20230020022A
(ko)
|
2017-10-10 |
2023-02-09 |
알파인 이뮨 사이언시즈, 인코포레이티드 |
Ctla-4 변이체 면역조절 단백질 및 이의 용도
|
JP7282760B2
(ja)
|
2017-10-18 |
2023-05-29 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
バリアントicosリガンド免疫調節タンパク質ならびに関連する組成物および方法
|
TW201932142A
(zh)
|
2017-10-20 |
2019-08-16 |
瑞士商赫孚孟拉羅股份公司 |
自單特異性抗體產生多特異性抗體之方法
|
KR20200074195A
(ko)
|
2017-10-30 |
2020-06-24 |
에프. 호프만-라 로슈 아게 |
단일특이적 항체로부터 다중특이적 항체의 생체내 생성 방법
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
AU2018358904A1
(en)
|
2017-11-01 |
2020-04-16 |
F. Hoffmann-La Roche Ag |
TriFab-contorsbody
|
EP3704150A1
(en)
|
2017-11-01 |
2020-09-09 |
F. Hoffmann-La Roche AG |
The compbody - a multivalent target binder
|
JP2021500902A
(ja)
|
2017-11-01 |
2021-01-14 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
新規tnfファミリーリガンド三量体含有抗原結合分子
|
CN111182944B
(zh)
|
2017-11-01 |
2022-11-22 |
豪夫迈·罗氏有限公司 |
双特异性2+1 Contorsbody
|
US10981992B2
(en)
|
2017-11-08 |
2021-04-20 |
Xencor, Inc. |
Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
|
JP2021502100A
(ja)
|
2017-11-08 |
2021-01-28 |
ゼンコア インコーポレイテッド |
新規抗pd−1配列を用いた二重特異性および単一特異性抗体
|
MX2020004756A
(es)
|
2017-11-16 |
2020-08-20 |
Novartis Ag |
Terapias de combinacion.
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
EP3720963A4
(en)
|
2017-12-05 |
2021-12-08 |
Chugai Seiyaku Kabushiki Kaisha |
ANTIGEN BINDING MOLECULE INCLUDING A VARIABLE REGION OF MODIFIED ANTIBODIES BINDING TO CD3 AND CD137
|
CN111655718A
(zh)
|
2017-12-19 |
2020-09-11 |
Xencor股份有限公司 |
经过工程化的il-2 fc融合蛋白
|
MX2020006119A
(es)
|
2017-12-21 |
2020-08-24 |
Hoffmann La Roche |
Anticuerpos de union a hla-a2/wt1.
|
CN109957026A
(zh)
*
|
2017-12-22 |
2019-07-02 |
成都恩沐生物科技有限公司 |
共价多特异性抗体
|
WO2019122054A1
(en)
|
2017-12-22 |
2019-06-27 |
F. Hoffmann-La Roche Ag |
Depletion of light chain mispaired antibody variants by hydrophobic interaction chromatography
|
TWI817974B
(zh)
|
2017-12-28 |
2023-10-11 |
日商中外製藥股份有限公司 |
細胞毒性誘導治療劑
|
SG11202006148UA
(en)
|
2018-01-03 |
2020-07-29 |
Alpine Immune Sciences Inc |
Multi-domain immunomodulatory proteins and methods of use thereof
|
WO2019145455A1
(en)
|
2018-01-24 |
2019-08-01 |
Genmab B.V. |
Polypeptide variants and uses thereof
|
WO2019152660A1
(en)
|
2018-01-31 |
2019-08-08 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
TWI786265B
(zh)
*
|
2018-02-02 |
2022-12-11 |
美商再生元醫藥公司 |
用於表徵蛋白質二聚合之系統及方法
|
EP3749359A1
(en)
|
2018-02-06 |
2020-12-16 |
F. Hoffmann-La Roche AG |
Treatment of ophthalmologic diseases
|
JP7475275B2
(ja)
|
2018-02-08 |
2024-04-26 |
ジェネンテック, インコーポレイテッド |
二重特異性抗原結合分子及びその使用方法
|
TWI829667B
(zh)
|
2018-02-09 |
2024-01-21 |
瑞士商赫孚孟拉羅股份公司 |
結合gprc5d之抗體
|
US20200399373A1
(en)
|
2018-02-14 |
2020-12-24 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule and combination
|
WO2019173832A2
(en)
|
2018-03-09 |
2019-09-12 |
AskGene Pharma, Inc. |
Novel cytokine prodrugs
|
SG11202008399QA
(en)
|
2018-03-12 |
2020-09-29 |
Genmab As |
Antibodies
|
EP3765516A2
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules and uses thereof
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
EP3773911A2
(en)
|
2018-04-04 |
2021-02-17 |
Xencor, Inc. |
Heterodimeric antibodies that bind fibroblast activation protein
|
US20210147547A1
(en)
|
2018-04-13 |
2021-05-20 |
Novartis Ag |
Dosage Regimens For Anti-Pd-L1 Antibodies And Uses Thereof
|
AR115052A1
(es)
|
2018-04-18 |
2020-11-25 |
Hoffmann La Roche |
Anticuerpos multiespecíficos y utilización de los mismos
|
MX2020010910A
(es)
|
2018-04-18 |
2021-02-09 |
Xencor Inc |
Proteinas de fusion heterodimericas dirigidas a pd-1 que contienen proteinas de fusion il-15 / il-15ra fc y dominios de union al antigeno pd-1 y usos de los mismos.
|
EP3781598A1
(en)
|
2018-04-18 |
2021-02-24 |
Xencor, Inc. |
Tim-3 targeted heterodimeric fusion proteins containing il-15/il-15ra fc-fusion proteins and tim-3 antigen binding domains
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
MX2020011552A
(es)
|
2018-05-03 |
2020-11-24 |
Genmab Bv |
Combinaciones de variantes de anticuerpos y usos de las mismas.
|
AU2019271147A1
(en)
|
2018-05-14 |
2020-12-17 |
Werewolf Therapeutics, Inc. |
Activatable cytokine polypeptides and methods of use thereof
|
CN113840832A
(zh)
|
2018-05-14 |
2021-12-24 |
狼人治疗公司 |
可活化白介素-2多肽及其使用方法
|
MX2020012270A
(es)
|
2018-05-16 |
2021-04-28 |
Janssen Biotech Inc |
Métodos para tratar cánceres y potenciar la eficacia de agentes terapéuticos para el redireccionamiento de células t.
|
US20200109195A1
(en)
|
2018-05-21 |
2020-04-09 |
Compass Therapeutics Llc |
Compositions and methods for enhancing the killing of target cells by nk cells
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
ES2945214T3
(es)
|
2018-05-23 |
2023-06-29 |
Celgene Corp |
Compuestos antiproliferativos y anticuerpo biespecífico contra BCMA y CD3 para uso combinado
|
JOP20190116A1
(ar)
|
2018-05-24 |
2019-11-24 |
Janssen Biotech Inc |
الأجسام المضادة لتكتل التمايز 33 (cd33)، والأجسام المضادة ثنائية النوعية لتكتل التمايز 33 (cd33)/تكتل التمايز 3 (cd3) واستخداماتها
|
PE20210634A1
(es)
|
2018-05-24 |
2021-03-23 |
Janssen Biotech Inc |
Anticuerpos anti-tmeff2 monoespecificos y multiespecificos y sus usos
|
AU2019274657A1
(en)
|
2018-05-24 |
2020-12-10 |
Janssen Biotech, Inc. |
PSMA binding agents and uses thereof
|
KR20210012007A
(ko)
|
2018-05-24 |
2021-02-02 |
얀센 바이오테크 인코포레이티드 |
항-cd3 항체 및 이의 용도
|
EP3801769A1
(en)
|
2018-05-25 |
2021-04-14 |
Novartis AG |
Combination therapy with chimeric antigen receptor (car) therapies
|
WO2019232244A2
(en)
|
2018-05-31 |
2019-12-05 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
CU20200089A7
(es)
|
2018-06-01 |
2021-07-02 |
Novartis Ag |
Moléculas de unión contra bcma
|
KR20210016448A
(ko)
|
2018-06-01 |
2021-02-15 |
컴퓨젠 엘티디. |
항-pvrig/항-tigit 이중특이적 항체 및 사용 방법
|
WO2019235420A1
(ja)
|
2018-06-04 |
2019-12-12 |
中外製薬株式会社 |
複合体を検出する方法
|
BR112020025048A2
(pt)
|
2018-06-13 |
2021-04-06 |
Novartis Ag |
Receptores de antígeno quimérico de bcma e usos dos mesmos
|
WO2019241758A1
(en)
|
2018-06-15 |
2019-12-19 |
Alpine Immune Sciences, Inc. |
Pd-1 variant immunomodulatory proteins and uses thereof
|
CA3102036A1
(en)
|
2018-06-18 |
2019-12-26 |
Anwita Biosciences, Inc. |
Cytokine fusion proteins and uses thereof
|
BR112020026033A2
(pt)
|
2018-06-19 |
2021-03-23 |
Atarga, Llc |
moléculas de anticorpo para complementar o componente 5 e usos das mesmas
|
US20210261669A1
(en)
|
2018-06-20 |
2021-08-26 |
Chugai Seiyaku Kabushiki Kaisha |
Method for activating immune response of target cell and composition therefor
|
WO2019243636A1
(en)
|
2018-06-22 |
2019-12-26 |
Genmab Holding B.V. |
Anti-cd37 antibodies and anti-cd20 antibodies, compositions and methods of use thereof
|
EP3818083A2
(en)
|
2018-07-03 |
2021-05-12 |
Elstar Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
TW202019518A
(zh)
|
2018-07-13 |
2020-06-01 |
丹麥商珍美寶股份有限公司 |
Cd38抗體之變體及其用途
|
US20240254252A1
(en)
|
2018-07-13 |
2024-08-01 |
Genmab A/S |
Trogocytosis-mediated therapy using cd38 antibodies
|
CN112534052B
(zh)
|
2018-07-25 |
2024-09-20 |
奥美药业有限公司 |
全新il-21前药及使用方法
|
WO2020021465A1
(en)
|
2018-07-25 |
2020-01-30 |
Advanced Accelerator Applications (Italy) S.R.L. |
Method of treatment of neuroendocrine tumors
|
WO2020045545A1
(ja)
|
2018-08-29 |
2020-03-05 |
中外製薬株式会社 |
抗体半分子、および抗体半分子のホモ二量体形成を抑制する方法
|
GB2576914A
(en)
|
2018-09-06 |
2020-03-11 |
Kymab Ltd |
Antigen-binding molecules comprising unpaired variable domains produced in mammals
|
WO2020068774A1
(en)
|
2018-09-24 |
2020-04-02 |
The Medical College Of Wisconsin, Inc. |
System and method for the development of cd30 bispecific antibodies for immunotherapy of cd30+ malignancies
|
CN113286812A
(zh)
|
2018-09-27 |
2021-08-20 |
西里欧发展公司 |
掩蔽型细胞因子多肽
|
MA53822A
(fr)
|
2018-10-03 |
2021-08-11 |
Xencor Inc |
Protéines de fusion fc hétérodimères d'il -12
|
JP7522106B2
(ja)
|
2018-10-04 |
2024-07-24 |
ジェンマブ ホールディング ビー.ブイ. |
二重特異性抗cd37抗体を含む医薬組成物
|
MA53862A
(fr)
|
2018-10-12 |
2022-01-19 |
Xencor Inc |
Protéines de fusion fc d'il-15/il-15ralpha ciblant pd-1 et utilisations dans des polythérapies faisant intervenir celles-ci
|
WO2020089051A1
(en)
|
2018-10-29 |
2020-05-07 |
F. Hoffmann-La Roche Ag |
Antibody formulation
|
US20210369842A1
(en)
|
2018-11-06 |
2021-12-02 |
Genmab A/S |
Antibody formulation
|
SG11202104864QA
(en)
|
2018-11-13 |
2021-06-29 |
Compass Therapeutics Llc |
Multispecific binding constructs against checkpoint molecules and uses thereof
|
JP2022510276A
(ja)
|
2018-11-30 |
2022-01-26 |
アルパイン イミューン サイエンシズ インコーポレイテッド |
Cd86バリアント免疫調節タンパク質およびその使用
|
WO2020115115A1
(en)
|
2018-12-05 |
2020-06-11 |
Morphosys Ag |
Multispecific antigen-binding molecules
|
GB201820687D0
(en)
|
2018-12-19 |
2019-01-30 |
Kymab Ltd |
Antagonists
|
WO2020128892A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Extended low dose regimens for mdm2 inhibitors
|
MX2021007392A
(es)
|
2018-12-20 |
2021-08-24 |
Novartis Ag |
Regimen de dosificacion y combinacion farmaceutica que comprende derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona.
|
WO2020132646A1
(en)
|
2018-12-20 |
2020-06-25 |
Xencor, Inc. |
Targeted heterodimeric fc fusion proteins containing il-15/il-15ra and nkg2d antigen binding domains
|
MY194642A
(en)
|
2018-12-21 |
2022-12-09 |
Hoffmann La Roche |
Antibodies binding to cd3
|
EP4015538A1
(en)
|
2018-12-21 |
2022-06-22 |
Kymab Limited |
Fixaxfx bispecific antibody with common light chain
|
CA3124796A1
(en)
|
2018-12-24 |
2020-07-02 |
Sanofi |
Multispecific binding proteins with mutant fab domains
|
WO2020136060A1
(en)
|
2018-12-28 |
2020-07-02 |
F. Hoffmann-La Roche Ag |
A peptide-mhc-i-antibody fusion protein for therapeutic use in a patient with amplified immune response
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
KR20210116540A
(ko)
|
2019-01-15 |
2021-09-27 |
얀센 바이오테크 인코포레이티드 |
소아 특발성 관절염의 치료를 위한 항-tnf 항체 조성물 및 방법
|
BR112021013824A2
(pt)
|
2019-01-18 |
2021-12-14 |
Janssen Biotech Inc |
Receptores de antígeno quiméricos gprc5d e células que expressam os mesmos
|
WO2020152544A1
(en)
|
2019-01-23 |
2020-07-30 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions for use in methods for the treatment of psoriatic arthritis
|
US10871640B2
(en)
|
2019-02-15 |
2020-12-22 |
Perkinelmer Cellular Technologies Germany Gmbh |
Methods and systems for automated imaging of three-dimensional objects
|
EA202192019A1
(ru)
|
2019-02-15 |
2021-11-02 |
Новартис Аг |
Производные 3-(1-оксо-5-(пиперидин-4-ил)изоиндолин-2-ил)пиперидин-2,6-диона и пути их применения
|
CA3123519A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
CN114127112A
(zh)
|
2019-02-21 |
2022-03-01 |
马伦戈治疗公司 |
与t细胞结合的多功能分子及其治疗自身免疫性病症的用途
|
GB2599228B
(en)
|
2019-02-21 |
2024-02-07 |
Marengo Therapeutics Inc |
Multifunctional molecules that bind to T cell related cancer cells and uses thereof
|
JP7579795B2
(ja)
|
2019-02-21 |
2024-11-08 |
マレンゴ・セラピューティクス,インコーポレーテッド |
NKp30に結合する抗体分子およびその使用
|
EP3927431A1
(en)
|
2019-02-21 |
2021-12-29 |
Marengo Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
WO2020172601A1
(en)
|
2019-02-21 |
2020-08-27 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
WO2020172553A1
(en)
|
2019-02-22 |
2020-08-27 |
Novartis Ag |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
BR112021016149A2
(pt)
|
2019-02-26 |
2021-10-13 |
Janssen Biotech, Inc. |
Terapias de combinação e estratificação de pacientes com anticorpos biespecíficos anti-egfr/c-met
|
CA3132185A1
(en)
|
2019-03-01 |
2020-09-10 |
Xencor, Inc. |
Heterodimeric antibodies that bind enpp3 and cd3
|
KR20210138033A
(ko)
|
2019-03-11 |
2021-11-18 |
얀센 바이오테크 인코포레이티드 |
항-Vβ17/항-CD123 이중특이성 항체
|
WO2020183418A1
(en)
|
2019-03-14 |
2020-09-17 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-il12/il23 antibody compositions
|
CN113840838A
(zh)
|
2019-03-14 |
2021-12-24 |
詹森生物科技公司 |
用于产生抗tnf抗体组合物的制造方法
|
EP3938392A1
(en)
|
2019-03-14 |
2022-01-19 |
Janssen Biotech, Inc. |
Methods for producing anti-tnf antibody compositions
|
EP3938391A1
(en)
|
2019-03-14 |
2022-01-19 |
Janssen Biotech, Inc. |
Methods for producing anti-tnf antibody compositions
|
CN113613676A
(zh)
|
2019-03-19 |
2021-11-05 |
中外制药株式会社 |
包含对抗原的结合活性因mta而变化的抗原结合结构域的抗原结合分子及用于获得该抗原结合结构域的文库
|
CN113677701A
(zh)
|
2019-03-29 |
2021-11-19 |
豪夫迈·罗氏有限公司 |
产生亲合结合多特异性抗体的方法
|
JP7249432B2
(ja)
|
2019-03-29 |
2023-03-30 |
エフ. ホフマン-ラ ロシュ アーゲー |
多価分子の機能分析のための、sprをベースとする結合アッセイ
|
MA55519A
(fr)
|
2019-03-29 |
2022-02-09 |
Atarga Llc |
Anticorps anti-fgf23
|
KR20220002899A
(ko)
|
2019-04-19 |
2022-01-07 |
얀센 바이오테크 인코포레이티드 |
항-psma/cd3 항체로 전립선암을 치료하는 방법
|
TW202106714A
(zh)
|
2019-04-25 |
2021-02-16 |
瑞士商赫孚孟拉羅股份公司 |
藉由多肽鏈交換製造抗體衍生之多肽
|
BR112021021210A2
(pt)
|
2019-04-25 |
2021-12-21 |
Hoffmann La Roche |
Conjunto de polipeptídeos, método para gerar um polipeptídeo heterodimérico, primeiro polipeptídeo precursor heterodimérico, segundo polipeptídeo precursor heterodimérico e composição farmacêutica
|
KR20220004052A
(ko)
|
2019-04-25 |
2022-01-11 |
에프. 호프만-라 로슈 아게 |
폴리펩티드 사슬 교환에 의해 활성화된 치료용 다중특이적 폴리펩티드
|
SG11202112021QA
(en)
|
2019-05-08 |
2021-11-29 |
Janssen Biotech Inc |
Materials and methods for modulating t cell mediated immunity
|
WO2020225456A1
(en)
|
2019-05-09 |
2020-11-12 |
Genmab B.V. |
Dosage regimens for a combination of anti-dr5 antibodies for use in treating cancer
|
EP3969907A1
(en)
|
2019-05-13 |
2022-03-23 |
F. Hoffmann-La Roche AG |
Interference-suppressed pharmacokinetic immunoassay
|
KR20220023988A
(ko)
|
2019-05-14 |
2022-03-03 |
웨어울프 세라퓨틱스, 인크. |
분리 모이어티 및 이의 사용 방법
|
WO2020230091A1
(en)
|
2019-05-14 |
2020-11-19 |
Janssen Biotech, Inc. |
Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors
|
JOP20210309A1
(ar)
|
2019-05-21 |
2023-01-30 |
Novartis Ag |
جزيئات ربط بـ cd19 واستخدامتها
|
US12037378B2
(en)
|
2019-05-21 |
2024-07-16 |
Novartis Ag |
Variant CD58 domains and uses thereof
|
KR20220010743A
(ko)
|
2019-05-21 |
2022-01-26 |
노파르티스 아게 |
Bcma에 대한 삼중특이적 결합 분자 및 이의 용도
|
KR20220029593A
(ko)
|
2019-06-03 |
2022-03-08 |
얀센 바이오테크 인코포레이티드 |
건선성 관절염의 치료를 위한 항-tnf 항체 조성물, 및 방법
|
CA3142676A1
(en)
|
2019-06-05 |
2020-12-10 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody cleavage site binding molecule
|
KR20220020879A
(ko)
|
2019-06-12 |
2022-02-21 |
에스크진 파마, 아이엔씨. |
새로운 il-15 프로드럭 및 이를 사용하는 방법
|
MX2021015536A
(es)
|
2019-06-19 |
2022-02-10 |
Hoffmann La Roche |
Metodo para la generacion de una celula que expresa proteina mediante integracion dirigida usando acido ribonucleico mensajero (arnm) de cre.
|
AU2020306672B2
(en)
|
2019-06-26 |
2023-08-24 |
F. Hoffmann-La Roche Ag |
Mammalian cell lines with SIRT-1 gene knockout
|
WO2021001289A1
(en)
|
2019-07-02 |
2021-01-07 |
F. Hoffmann-La Roche Ag |
Immunoconjugates comprising a mutant interleukin-2 and an anti-cd8 antibody
|
PE20220392A1
(es)
|
2019-07-10 |
2022-03-18 |
Chugai Pharmaceutical Co Ltd |
Moleculas de union a claudina-6 y usos de las mismas
|
AU2020313521A1
(en)
|
2019-07-12 |
2022-02-17 |
Janssen Pharmaceutica Nv |
Binding agents and uses thereof
|
AR119393A1
(es)
|
2019-07-15 |
2021-12-15 |
Hoffmann La Roche |
Anticuerpos que se unen a nkg2d
|
KR20220034857A
(ko)
|
2019-07-16 |
2022-03-18 |
사노피 |
알츠하이머병의 치료를 위한 중화 항-아밀로이드 베타 항체
|
CR20220025A
(es)
|
2019-07-26 |
2022-05-04 |
Janssen Biotech Inc |
Proteínas que comprenden dominios de unión al antígeno de la peptidasa 2 relacionada con la calicreína y sus usos
|
PE20220394A1
(es)
|
2019-07-31 |
2022-03-18 |
Hoffmann La Roche |
Anticuerpos que se fijan a gprc5d
|
EP4004045A1
(en)
|
2019-07-31 |
2022-06-01 |
F. Hoffmann-La Roche AG |
Antibodies binding to gprc5d
|
GB201910900D0
(en)
|
2019-07-31 |
2019-09-11 |
Scancell Ltd |
Modified fc-regions to enhance functional affinity of antibodies and antigen binding fragments thereof
|
WO2021026409A1
(en)
|
2019-08-08 |
2021-02-11 |
Regeneron Pharmaceuticals, Inc. |
Novel antigen binding molecule formats
|
CN114222764A
(zh)
|
2019-08-12 |
2022-03-22 |
奥美药业有限公司 |
可优先结合IL-2Rα的IL-2融合蛋白
|
CN114258400A
(zh)
|
2019-08-15 |
2022-03-29 |
詹森生物科技公司 |
用于改进的单链可变片段的材料和方法
|
JP2022545439A
(ja)
|
2019-08-21 |
2022-10-27 |
アスクジーン・ファーマ・インコーポレイテッド |
新規il-21プロドラッグおよびその使用方法
|
AU2020353235A1
(en)
|
2019-09-28 |
2022-03-31 |
AskGene Pharma, Inc. |
Cytokine prodrugs and dual-prodrugs
|
TW202128757A
(zh)
|
2019-10-11 |
2021-08-01 |
美商建南德克公司 |
具有改善之特性的 PD-1 標靶 IL-15/IL-15Rα FC 融合蛋白
|
US20240301053A1
(en)
|
2019-10-21 |
2024-09-12 |
Novartis Ag |
Combination therapies with venetoclax and tim-3 inhibitors
|
CN114786680A
(zh)
|
2019-10-21 |
2022-07-22 |
诺华股份有限公司 |
Tim-3抑制剂及其用途
|
AU2020379735A1
(en)
|
2019-11-05 |
2022-05-26 |
Regeneron Pharmaceuticals, Inc. |
N-terminal SCFV multispecific binding molecules
|
US20220411529A1
(en)
|
2019-11-06 |
2022-12-29 |
Genmab B.V. |
Antibody variant combinations and uses thereof
|
CA3155981A1
(en)
|
2019-11-14 |
2021-05-20 |
William Winston |
Activatable cytokine polypeptides and methods of use thereof
|
IL293046A
(en)
|
2019-11-18 |
2022-07-01 |
Janssen Biotech Inc |
Anti-cd79 chimeric antigen receptors, car-t cells and uses thereof
|
BR112022010206A2
(pt)
|
2019-11-26 |
2022-11-29 |
Novartis Ag |
Receptores de antígeno quiméricos e usos dos mesmos
|
CA3164226A1
(en)
|
2019-12-11 |
2021-06-17 |
Cilag Gmbh International |
Multispecific binding molecules comprising ltbr and edb binding domains and uses thereof
|
KR20220113791A
(ko)
|
2019-12-18 |
2022-08-16 |
에프. 호프만-라 로슈 아게 |
이중특이적 항-ccl2 항체
|
WO2021122875A1
(en)
|
2019-12-18 |
2021-06-24 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a2/mage-a4
|
CN115023444A
(zh)
|
2019-12-20 |
2022-09-06 |
再生元制药公司 |
新型il2激动剂及其使用方法
|
EP4077389A1
(en)
|
2019-12-20 |
2022-10-26 |
Novartis AG |
Combination of anti tim-3 antibody mbg453 and anti tgf-beta antibody nis793, with or without decitabine or the anti pd-1 antibody spartalizumab, for treating myelofibrosis and myelodysplastic syndrome
|
US20230058982A1
(en)
|
2019-12-27 |
2023-02-23 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-ctla-4 antibody and use thereof
|
US11913945B2
(en)
|
2020-01-02 |
2024-02-27 |
Hoffmann-La Roche Inc. |
Method for determining the amount of a therapeutic antibody in the brain
|
WO2021138407A2
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to cd33 and uses thereof
|
WO2021142471A1
(en)
|
2020-01-11 |
2021-07-15 |
AskGene Pharma, Inc. |
Novel masked cytokines and methods of use thereof
|
CN114980927A
(zh)
|
2020-01-16 |
2022-08-30 |
健玛保 |
Cd38抗体的配制剂及其用途
|
EP4090762A1
(en)
|
2020-01-17 |
2022-11-23 |
Becton, Dickinson and Company |
Methods and compositions for single cell secretomics
|
TW202140037A
(zh)
|
2020-01-17 |
2021-11-01 |
瑞士商諾華公司 |
組合療法
|
IL272194A
(en)
|
2020-01-22 |
2021-07-29 |
Yeda Res & Dev |
Multi-target antibodies for use in the treatment of diseases
|
IL272389A
(en)
|
2020-01-30 |
2021-08-31 |
Yeda Res & Dev |
Kits containing antibodies to PD-L1 and their uses in therapy
|
KR20220144377A
(ko)
|
2020-01-30 |
2022-10-26 |
우모자 바이오파마 인코포레이티드 |
이중특이적 형질도입 촉진제
|
WO2021155916A1
(en)
|
2020-02-04 |
2021-08-12 |
BioNTech SE |
Treatment involving antigen vaccination and binding agents binding to pd-l1 and cd137
|
TW202144388A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
TW202144389A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在多發性骨髓瘤中表現之新抗原及其用途
|
JP2023515211A
(ja)
|
2020-02-27 |
2023-04-12 |
ノバルティス アーゲー |
キメラ抗原受容体発現細胞を作製する方法
|
PE20240020A1
(es)
|
2020-03-13 |
2024-01-04 |
Janssen Biotech Inc |
Materiales y metodos para la union de siglec-3/cd33
|
CA3168613A1
(en)
|
2020-03-18 |
2021-09-23 |
Genmab A/S |
Antibodies binding to b7h4
|
WO2021190980A1
(en)
|
2020-03-22 |
2021-09-30 |
Quadrucept Bio Limited |
Multimers for viral strain evolution
|
JP2023520773A
(ja)
|
2020-03-27 |
2023-05-19 |
ノバルティス アーゲー |
増殖性疾患及び自己免疫疾患を治療するための二重特異性組合せ治療
|
CA3175577A1
(en)
|
2020-03-30 |
2021-10-07 |
Mie University |
Bispecific antibody
|
SG11202105302PA
(en)
|
2020-03-31 |
2021-11-29 |
Chugai Pharmaceutical Co Ltd |
Dll3-targeting multispecific antigen-binding molecules and uses thereof
|
CA3173519A1
(en)
|
2020-03-31 |
2021-10-07 |
Vishnu Priyanka Reddy CHICHILI |
Method for producing multispecific antigen-binding molecules
|
KR20230004494A
(ko)
|
2020-04-15 |
2023-01-06 |
에프. 호프만-라 로슈 아게 |
면역접합체
|
EP4135841A1
(en)
|
2020-04-15 |
2023-02-22 |
Voyager Therapeutics, Inc. |
Tau binding compounds
|
WO2021209953A1
(en)
|
2020-04-16 |
2021-10-21 |
Janssen Biotech, Inc. |
Systems, materials, and methods for reversed-phase high performance liquid chromatography (rp-hplc) for monitoring formation of multi-specific molecules
|
GB202005879D0
(en)
|
2020-04-22 |
2020-06-03 |
Petmedix Ltd |
Heterodimeric proteins
|
WO2021217085A1
(en)
|
2020-04-24 |
2021-10-28 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to t cell related cancer cells and uses thereof
|
CN113563473A
(zh)
|
2020-04-29 |
2021-10-29 |
三生国健药业(上海)股份有限公司 |
四价双特异性抗体、其制备方法和用途
|
CA3180173A1
(en)
|
2020-04-30 |
2021-11-04 |
Bristol-Myers Squibb Company |
Methods of treating cytokine-related adverse events
|
CN116096758A
(zh)
|
2020-05-01 |
2023-05-09 |
诺华股份有限公司 |
工程化免疫球蛋白
|
TW202208414A
(zh)
|
2020-05-08 |
2022-03-01 |
美商艾爾潘免疫科學有限公司 |
April及baff抑制性免疫調節蛋白及其使用方法
|
EP4146175A1
(en)
|
2020-05-08 |
2023-03-15 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20
|
PE20230387A1
(es)
|
2020-05-11 |
2023-03-06 |
Hoffmann La Roche |
Tratamiento conjunto con pbmc modificadas y un inmunoconjugado
|
CA3182697A1
(en)
|
2020-05-11 |
2021-11-18 |
Janssen Biotech, Inc. |
Methods for treating multiple myeloma
|
CA3183151A1
(en)
|
2020-05-12 |
2021-11-18 |
Regeneron Pharmaceuticals, Inc. |
Novel il10 agonists and methods of use thereof
|
WO2021231976A1
(en)
|
2020-05-14 |
2021-11-18 |
Xencor, Inc. |
Heterodimeric antibodies that bind prostate specific membrane antigen (psma) and cd3
|
CN115667515A
(zh)
|
2020-05-22 |
2023-01-31 |
中外制药株式会社 |
中和具有凝血因子viii(f.viii)功能替代活性的物质的抗体
|
BR112022023978A2
(pt)
|
2020-05-27 |
2023-02-07 |
Janssen Biotech Inc |
Proteínas que compreendem domínios de ligação ao antígeno cd3 e usos dos mesmos
|
GB202008860D0
(en)
|
2020-06-11 |
2020-07-29 |
Univ Oxford Innovation Ltd |
BTLA antibodies
|
WO2021255146A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3 and cea
|
CR20220637A
(es)
|
2020-06-19 |
2023-01-31 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y cd19
|
AR122657A1
(es)
|
2020-06-19 |
2022-09-28 |
Hoffmann La Roche |
Moléculas de unión al dominio fc de activación inmunitaria
|
WO2021255142A1
(en)
|
2020-06-19 |
2021-12-23 |
F. Hoffmann-La Roche Ag |
Antibodies binding to cd3
|
CN115916826A
(zh)
|
2020-06-19 |
2023-04-04 |
豪夫迈·罗氏有限公司 |
与CD3和FolR1结合的抗体
|
MX2022015852A
(es)
|
2020-06-23 |
2023-01-24 |
Novartis Ag |
Regimen de dosificacion que comprende derivados de 3-(1-oxoisoindolin-2-il)piperidina-2,6-diona.
|
AU2021308712A1
(en)
|
2020-07-16 |
2023-02-02 |
Novartis Ag |
Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules
|
JP2023534726A
(ja)
|
2020-07-23 |
2023-08-10 |
ジェンマブ ビー.ブイ. |
多発性骨髄腫の治療に使用するための抗dr5抗体と免疫調節イミド薬との併用
|
WO2022026592A2
(en)
|
2020-07-28 |
2022-02-03 |
Celltas Bio, Inc. |
Antibody molecules to coronavirus and uses thereof
|
KR20230041819A
(ko)
|
2020-07-29 |
2023-03-24 |
얀센 바이오테크 인코포레이티드 |
Hla-g 항원-결합 도메인을 포함하는 단백질 및 이의 용도
|
IL300225A
(en)
|
2020-07-31 |
2023-03-01 |
Chugai Pharmaceutical Co Ltd |
A pharmaceutical composition including chimeric receptor expressing cells
|
JP2023536164A
(ja)
|
2020-08-03 |
2023-08-23 |
ノバルティス アーゲー |
ヘテロアリール置換3-(1-オキソイソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用
|
JP2023537470A
(ja)
|
2020-08-03 |
2023-09-01 |
ヤンセン バイオテツク,インコーポレーテツド |
ウイルス治療における多方向バイオ輸送のための材料及び方法
|
US20230287088A1
(en)
|
2020-08-06 |
2023-09-14 |
BioNTech SE |
Binding agents for coronavirus s protein
|
IL300666A
(en)
|
2020-08-19 |
2023-04-01 |
Xencor Inc |
ANTI–CD28 COMPOSITIONS
|
WO2022046920A2
(en)
|
2020-08-26 |
2022-03-03 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
AU2021333779A1
(en)
|
2020-08-26 |
2023-04-13 |
Marengo Therapeutics, Inc. |
Methods of detecting TRBC1 or TRBC2
|
CN116917316A
(zh)
|
2020-08-26 |
2023-10-20 |
马伦戈治疗公司 |
与NKp30结合的抗体分子及其用途
|
WO2022044248A1
(ja)
|
2020-08-28 |
2022-03-03 |
中外製薬株式会社 |
ヘテロ二量体Fcポリペプチド
|
WO2022043557A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
WO2022043558A1
(en)
|
2020-08-31 |
2022-03-03 |
Advanced Accelerator Applications International Sa |
Method of treating psma-expressing cancers
|
WO2022049220A2
(en)
|
2020-09-02 |
2022-03-10 |
Genmab A/S |
Antibody therapy
|
AU2021342342A1
(en)
|
2020-09-10 |
2023-04-13 |
Genmab A/S |
Bispecific antibodies against CD3 and CD20 for treating chronic lymphocytic leukemia
|
US20240034812A1
(en)
|
2020-09-10 |
2024-02-01 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
IL301102A
(en)
|
2020-09-10 |
2023-05-01 |
Genmab As |
A bispecific antibody against CD3 and CD20 in combination therapy for the treatment of diffuse large B-cell lymphoma
|
BR112023004351A2
(pt)
|
2020-09-10 |
2023-04-04 |
Genmab As |
Método para tratar linfoma folicular em um sujeito humano
|
MX2023002541A
(es)
|
2020-09-10 |
2023-03-14 |
Genmab As |
Anticuerpo biespecifico contra el cumulo de diferenciacion 3 (cd3) y el cumulo de diferenciacion 20 (cd20) en terapia combinada para el tratamiento del linfoma difuso de celulas b grandes.
|
JP2023542290A
(ja)
|
2020-09-10 |
2023-10-06 |
ジェンマブ エー/エス |
濾胞性リンパ腫を治療するための併用療法におけるcd3及びcd20に対する二重特異性抗体
|
WO2022056192A1
(en)
|
2020-09-11 |
2022-03-17 |
Janssen Biotech, Inc. |
Methods and compositions for modulating beta chain mediated immunity
|
EP4211156A1
(en)
|
2020-09-14 |
2023-07-19 |
Sutro Biopharma, Inc. |
Method for large scale production of antibodies using a cell-free protein synthesis system
|
KR20230068415A
(ko)
|
2020-09-24 |
2023-05-17 |
에프. 호프만-라 로슈 아게 |
유전자 녹아웃을 갖는 포유류 세포주
|
IL301513A
(en)
|
2020-10-02 |
2023-05-01 |
Genmab As |
Antibodies able to bind to ROR2 and bispecific antibodies that bind to ROR2 and CD3
|
EP4228693A1
(en)
|
2020-10-13 |
2023-08-23 |
Janssen Biotech, Inc. |
Bioengineered t cell mediated immunity, materials and other methods for modulating cluster of differentiation iv &/or viii
|
JP2023548034A
(ja)
|
2020-10-22 |
2023-11-15 |
ヤンセン バイオテツク,インコーポレーテツド |
デルタ様リガンド3(dll3)抗原結合ドメインを含むタンパク質及びその使用
|
JP2023548045A
(ja)
|
2020-10-23 |
2023-11-15 |
アッシャー バイオセラピューティクス, インコーポレイテッド |
免疫細胞機能をモジュレートするためのcd8抗原結合分子を有する融合物
|
TW202233674A
(zh)
|
2020-10-28 |
2022-09-01 |
美商健生生物科技公司 |
用於調節δγ鏈介導之免疫的組成物及方法
|
IL302388A
(en)
|
2020-11-02 |
2023-06-01 |
Attralus Inc |
SAP FC fusion proteins and methods of use
|
CA3199839A1
(en)
|
2020-11-06 |
2022-05-12 |
Novartis Ag |
Anti-cd19 agent and b cell targeting agent combination therapy for treating b cell malignancies
|
JP2023548529A
(ja)
|
2020-11-06 |
2023-11-17 |
ノバルティス アーゲー |
Cd19結合分子及びその使用
|
CN117120477A
(zh)
|
2020-11-10 |
2023-11-24 |
上海齐鲁制药研究中心有限公司 |
针对密蛋白18a2和cd3的双特异性抗体及其应用
|
EP4243857A1
(en)
|
2020-11-13 |
2023-09-20 |
Novartis AG |
Combination therapies with chimeric antigen receptor (car)-expressing cells
|
KR20230120665A
(ko)
|
2020-12-17 |
2023-08-17 |
에프. 호프만-라 로슈 아게 |
항-hla-g 항체 및 이의 용도
|
JP2023553692A
(ja)
|
2020-12-18 |
2023-12-25 |
エフ. ホフマン-ラ ロシュ アーゲー |
標的治療のための前駆体タンパク質及びキット
|
CN116670282A
(zh)
|
2020-12-22 |
2023-08-29 |
豪夫迈·罗氏有限公司 |
靶向xbp1的寡核苷酸
|
KR20230117406A
(ko)
|
2021-01-06 |
2023-08-08 |
에프. 호프만-라 로슈 아게 |
Pd1-lag3 이중특이성 항체와 cd20 t 세포 이중특이성항체를 이용한 조합 요법
|
WO2022148853A1
(en)
|
2021-01-11 |
2022-07-14 |
F. Hoffmann-La Roche Ag |
Immunoconjugates
|
US20240076355A1
(en)
|
2021-01-14 |
2024-03-07 |
AskGene Pharma, Inc. |
Interferon Prodrugs and Methods of Making and Using the Same
|
EP4284838A2
(en)
|
2021-01-28 |
2023-12-06 |
Janssen Biotech, Inc. |
Psma binding proteins and uses thereof
|
US20240141060A1
(en)
|
2021-01-29 |
2024-05-02 |
Novartis Ag |
Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof
|
CN117500824A
(zh)
|
2021-02-01 |
2024-02-02 |
奥美药业有限公司 |
包含IL-10或TGF-β激动剂多肽的嵌合分子
|
PE20241170A1
(es)
|
2021-02-16 |
2024-05-28 |
Janssen Pharmaceutica Nv |
Anticuerpo triespecifico dirigido a bcma, gprc5d, y cd3
|
WO2022177902A1
(en)
|
2021-02-16 |
2022-08-25 |
Janssen Biotech, Inc. |
Materials and methods for enhanced linker targeting
|
WO2022178103A1
(en)
|
2021-02-17 |
2022-08-25 |
AskGene Pharma, Inc. |
Il-2 receptor beta subunit mutants
|
CN116888473A
(zh)
|
2021-02-18 |
2023-10-13 |
豪夫迈·罗氏有限公司 |
用于解析复杂、多步骤抗体相互作用的方法
|
WO2022184659A1
(en)
|
2021-03-01 |
2022-09-09 |
Quadrucept Bio Limited |
Antibody domains & multimers
|
US20220298248A1
(en)
|
2021-03-09 |
2022-09-22 |
Janssen Biotech, Inc. |
Treatment of Cancers Lacking EGFR- Activating Mutations
|
US11739144B2
(en)
|
2021-03-09 |
2023-08-29 |
Xencor, Inc. |
Heterodimeric antibodies that bind CD3 and CLDN6
|
WO2022192586A1
(en)
|
2021-03-10 |
2022-09-15 |
Xencor, Inc. |
Heterodimeric antibodies that bind cd3 and gpc3
|
US20240150484A1
(en)
|
2021-03-12 |
2024-05-09 |
Genmab A/S |
Non-activating antibody variants
|
AR125212A1
(es)
|
2021-03-24 |
2023-06-28 |
Janssen Biotech Inc |
Proteínas que comprenden dominios de unión al antígeno de cd3 y usos de estas
|
CA3214259A1
(en)
|
2021-03-24 |
2022-09-29 |
Janssen Biotech, Inc. |
Antibody targeting cd22 and cd79b
|
JP2024511115A
(ja)
|
2021-03-24 |
2024-03-12 |
ヤンセン バイオテツク,インコーポレーテツド |
CD79b、CD20、及びCD3を標的とする三重特異性抗体
|
WO2022206872A1
(zh)
|
2021-03-31 |
2022-10-06 |
江苏恒瑞医药股份有限公司 |
截短的taci多肽及其融合蛋白和用途
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
CN117597359A
(zh)
|
2021-04-08 |
2024-02-23 |
马伦戈治疗公司 |
与tcr结合的多功能分子及其用途
|
CA3217520A1
(en)
|
2021-04-22 |
2022-10-27 |
Guangdong Fapon Biopharma Inc. |
Bispecific multifunctional fusion polypeptide
|
WO2022228705A1
(en)
|
2021-04-30 |
2022-11-03 |
F. Hoffmann-La Roche Ag |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
IL307821A
(en)
|
2021-04-30 |
2023-12-01 |
Hoffmann La Roche |
Dosage for treatment with BISPIFIC ANTI-CD20/ANTI-CD3 antibody
|
CN117597365A
(zh)
|
2021-05-04 |
2024-02-23 |
再生元制药公司 |
多特异性fgf21受体激动剂及其应用
|
CA3219609A1
(en)
|
2021-05-04 |
2022-11-10 |
Regeneron Pharmaceuticals, Inc. |
Multispecific fgf21 receptor agonists and their uses
|
KR20240004949A
(ko)
|
2021-05-07 |
2024-01-11 |
젠맵 에이/에스 |
B7h4 및 cd3에 결합하는 이중특이적 항체를 포함하는 제약 조성물
|
AU2022269139A1
(en)
|
2021-05-07 |
2023-11-16 |
Alpine Immune Sciences, Inc. |
Methods of dosing and treatment with a taci-fc fusion immunomodulatory protein
|
KR20240006586A
(ko)
|
2021-05-12 |
2024-01-15 |
지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 |
Rankl 및 ngf에 특이적으로 결합하는 항원 결합 분자, 및 이의 의학적 용도
|
CA3219388A1
(en)
|
2021-05-14 |
2022-11-17 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Antigen-binding molecule
|
TW202309094A
(zh)
|
2021-05-18 |
2023-03-01 |
美商健生生物科技公司 |
用於識別癌症患者以進行組合治療之方法
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
EP4340866A1
(en)
|
2021-05-19 |
2024-03-27 |
Asher Biotherapeutics, Inc. |
Il-21 polypeptides and targeted constructs
|
CA3221735A1
(en)
|
2021-06-18 |
2022-12-22 |
F. Hoffmann-La Roche Ag |
Bispecific anti-ccl2 antibodies
|
BR112023027006A2
(pt)
|
2021-06-21 |
2024-03-12 |
BioNTech SE |
Método para reduzir ou prevenir a progressão de um tumor ou tratar um câncer em um sujeito, e, agente de ligação
|
TW202306989A
(zh)
|
2021-06-22 |
2023-02-16 |
瑞士商諾華公司 |
用於在治療化膿性汗腺炎中使用的雙特異性抗體
|
JP7477127B2
(ja)
|
2021-06-25 |
2024-05-01 |
中外製薬株式会社 |
抗ctla-4抗体の使用
|
MX2023013897A
(es)
|
2021-06-25 |
2023-12-11 |
Chugai Pharmaceutical Co Ltd |
Anticuerpo anti-antigeno 4 del linfocito t citotoxico (anti-ctla-4).
|
AU2022302170A1
(en)
|
2021-07-02 |
2023-12-21 |
F. Hoffmann-La Roche Ag |
Methods and compositions for treating cancer
|
IL309997A
(en)
|
2021-07-09 |
2024-03-01 |
Janssen Biotech Inc |
Production methods for the production of anti-TNF antibody compositions
|
EP4367138A1
(en)
|
2021-07-09 |
2024-05-15 |
Janssen Biotech, Inc. |
Manufacturing methods for producing anti-il12/il23 antibody compositions
|
CN117957251A
(zh)
|
2021-07-09 |
2024-04-30 |
詹森生物科技公司 |
用于制备抗tnf抗体组合物的制造方法
|
AU2022309554A1
(en)
|
2021-07-14 |
2024-02-22 |
Jiangsu Hengrui Pharmaceuticals Co., Ltd. |
Antigen-binding molecule specifically binding to hgfr and egfr, and pharmaceutical use thereof
|
MX2024000882A
(es)
|
2021-07-19 |
2024-04-23 |
Regeneron Pharma |
Agonistas del receptor de il12 y métodos para su uso.
|
KR20240035556A
(ko)
*
|
2021-07-19 |
2024-03-15 |
추가이 세이야쿠 가부시키가이샤 |
융합 폴리펩타이드를 이용하는 프로테아제 매개성의 표적 특이적 사이토카인 송달
|
JP2024528631A
(ja)
|
2021-07-22 |
2024-07-30 |
エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト |
ヘテロ二量体Fcドメイン抗体
|
JP2024527020A
(ja)
|
2021-07-27 |
2024-07-19 |
モルフォシス・アーゲー |
抗原結合分子の組合せ
|
WO2023010095A1
(en)
|
2021-07-28 |
2023-02-02 |
F. Hoffmann-La Roche Ag |
Methods and compositions for treating cancer
|
CA3226428A1
(en)
|
2021-08-02 |
2023-02-09 |
Hangzhou Unogen Biotech, Ltd |
Anti-cd38 antibodies, anti-cd3 antibodies, and bispecific antibodies, and uses thereof
|
WO2023015169A1
(en)
|
2021-08-02 |
2023-02-09 |
Tavotek Biotech (Suzhou) Ltd |
Anti-cdh17 monoclonal and bispecific antibodies and uses thereof
|
AU2022331241A1
(en)
|
2021-08-16 |
2024-03-28 |
Regeneron Pharmaceuticals, Inc. |
Novel il27 receptor agonists and methods of use thereof
|
AU2022338208A1
(en)
|
2021-09-06 |
2024-03-21 |
Genmab A/S |
Antibodies capable of binding to cd27, variants thereof and uses thereof
|
AU2022344595A1
(en)
|
2021-09-13 |
2024-05-02 |
Janssen Biotech, Inc |
CD33 X Vδ2 MULTISPECIFIC ANTIBODIES FOR THE TREATMENT OF CANCER
|
IL286430A
(en)
|
2021-09-14 |
2023-04-01 |
Yeda Res & Dev |
Multispecific antibodies for use in the treatment of diseases
|
EP4405396A2
(en)
|
2021-09-20 |
2024-07-31 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
JP2024534531A
(ja)
|
2021-09-23 |
2024-09-20 |
江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 |
抗klb抗体及び使用
|
WO2023046322A1
(en)
|
2021-09-24 |
2023-03-30 |
Janssen Pharmaceutica Nv |
Proteins comprising cd20 binding domains, and uses thereof
|
CA3232349A1
(en)
*
|
2021-09-29 |
2023-04-06 |
Mark GRECI |
Antigen binding polypeptides, antigen binding polypeptide complexes and methods of use thereof
|
WO2023053282A1
(ja)
|
2021-09-29 |
2023-04-06 |
中外製薬株式会社 |
がんの治療に用いるための細胞傷害誘導治療剤
|
JP2024536870A
(ja)
|
2021-09-30 |
2024-10-08 |
江▲蘇▼恒瑞医▲薬▼股▲フン▼有限公司 |
抗il23抗体融合タンパク質及び使用
|
AR127298A1
(es)
|
2021-10-08 |
2024-01-10 |
Genmab As |
Anticuerpos que se unen a cd30 y cd3
|
IL311956A
(en)
|
2021-10-08 |
2024-06-01 |
Chugai Pharmaceutical Co Ltd |
Method for preparing a prefilled syringe formulation
|
IL312005A
(en)
|
2021-10-14 |
2024-06-01 |
Hoffmann La Roche |
NEW INTERLEUKIN-7 IMMUNOCONJUGATES
|
CN118139648A
(zh)
|
2021-10-14 |
2024-06-04 |
豪夫迈·罗氏有限公司 |
用于治疗癌症的替代的PD1-IL7v免疫缀合物
|
CN118355030A
(zh)
|
2021-10-18 |
2024-07-16 |
拓维创新生物科技(香港)有限公司 |
抗EGFR抗体、抗cMET抗体、抗VEGF抗体、多特异性抗体及其用途
|
EP4423123A1
(en)
|
2021-10-28 |
2024-09-04 |
Novartis AG |
Engineered fc variants
|
EP4426734A1
(en)
|
2021-11-01 |
2024-09-11 |
Janssen Biotech, Inc. |
Compositions and methods for the modulation of beta chain-mediated immunity
|
WO2023081705A1
(en)
|
2021-11-03 |
2023-05-11 |
Janssen Biotech, Inc. |
Methods of treating cancers and enhancing efficacy of bcmaxcd3 bispecific antibodies
|
EP4430079A1
(en)
|
2021-11-11 |
2024-09-18 |
Regeneron Pharmaceuticals, Inc. |
Cd20-pd1 binding molecules and methods of use thereof
|
WO2023092004A1
(en)
|
2021-11-17 |
2023-05-25 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of tau-related disorders
|
KR20240111783A
(ko)
|
2021-11-22 |
2024-07-17 |
얀센 바이오테크 인코포레이티드 |
면역 반응을 위한 강화된 다중특이성 결합제를 포함하는 조성물
|
WO2023094282A1
(en)
|
2021-11-25 |
2023-06-01 |
F. Hoffmann-La Roche Ag |
Quantification of low amounts of antibody sideproducts
|
WO2023103788A1
(zh)
|
2021-12-06 |
2023-06-15 |
北京三诺佳邑生物技术有限责任公司 |
特异性结合肺炎克雷伯菌o2抗原和o1抗原的双特异性抗体以及组合物
|
US20230183360A1
(en)
|
2021-12-09 |
2023-06-15 |
Janssen Biotech, Inc. |
Use of Amivantamab to Treat Colorectal Cancer
|
AR127887A1
(es)
|
2021-12-10 |
2024-03-06 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y plap
|
EP4457342A1
(en)
|
2021-12-29 |
2024-11-06 |
Bristol-Myers Squibb Company |
Generation of landing pad cell lines
|
IL314068A
(en)
|
2022-01-24 |
2024-09-01 |
Novimmune Sa |
Preparations and methods for selective activation of cytokine signaling pathways
|
WO2023144290A1
(en)
|
2022-01-28 |
2023-08-03 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
AU2023213099A1
(en)
|
2022-01-28 |
2024-07-18 |
Genmab A/S |
Bispecific antibody against cd3 and cd20 in combination therapy for treating diffuse large b-cell lymphoma
|
CN118574855A
(zh)
|
2022-02-07 |
2024-08-30 |
江苏恒瑞医药股份有限公司 |
特异性结合psma和cd3的抗原结合分子及其医药用途
|
TW202342057A
(zh)
|
2022-02-07 |
2023-11-01 |
美商健生生物科技公司 |
用於減少用egfr/met雙特異性抗體治療之患者的輸注相關反應之方法
|
US20230383010A1
(en)
|
2022-02-07 |
2023-11-30 |
Visterra, Inc. |
Anti-idiotype antibody molecules and uses thereof
|
KR20240145492A
(ko)
|
2022-02-11 |
2024-10-07 |
지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 |
면역접합체 및 이의 용도
|
IL314916A
(en)
|
2022-03-07 |
2024-10-01 |
Novimmune Sa |
Bispecific CD28 antibodies for targeted T cell activation
|
US12122850B2
(en)
|
2022-03-14 |
2024-10-22 |
LamKap Bio gamma AG |
Bispecific GPC3xCD28 and GPC3xCD3 antibodies and their combination for targeted killing of GPC3 positive malignant cells
|
CN118660910A
(zh)
|
2022-03-14 |
2024-09-17 |
江苏恒瑞医药股份有限公司 |
特异性结合gprc5d和cd3的抗原结合分子及其医药用途
|
WO2023174521A1
(en)
|
2022-03-15 |
2023-09-21 |
Genmab A/S |
Binding agents binding to epcam and cd137
|
IL314211A
(en)
|
2022-03-23 |
2024-09-01 |
Genentech Inc |
Combined treatment of bispecific antibody and chemotherapy against CD20/ANTI-CD3
|
IL315526A
(en)
|
2022-03-29 |
2024-11-01 |
Ngm Biopharmaceuticals Inc |
ILT3 and CD3 binding agents and methods of using them
|
WO2023198839A2
(en)
|
2022-04-13 |
2023-10-19 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20
|
WO2023198727A1
(en)
|
2022-04-13 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions of anti-cd20/anti-cd3 bispecific antibodies and methods of use
|
WO2023202967A1
(en)
|
2022-04-19 |
2023-10-26 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
WO2023209568A1
(en)
|
2022-04-26 |
2023-11-02 |
Novartis Ag |
Multispecific antibodies targeting il-13 and il-18
|
WO2023220647A1
(en)
|
2022-05-11 |
2023-11-16 |
Regeneron Pharmaceuticals, Inc. |
Multispecific binding molecule proproteins and uses thereof
|
TW202409090A
(zh)
|
2022-05-12 |
2024-03-01 |
丹麥商珍美寶股份有限公司 |
在組合療法中能夠結合到cd27之結合劑
|
TW202413412A
(zh)
|
2022-05-12 |
2024-04-01 |
丹麥商珍美寶股份有限公司 |
在組合療法中能夠結合到cd27之結合劑
|
WO2023220695A2
(en)
|
2022-05-13 |
2023-11-16 |
Voyager Therapeutics, Inc. |
Compositions and methods for the treatment of her2 positive cancer
|
US20230382969A1
(en)
|
2022-05-27 |
2023-11-30 |
Regeneron Pharmaceuticals, Inc. |
Interleukin-2 proproteins and uses thereof
|
WO2023232961A1
(en)
|
2022-06-03 |
2023-12-07 |
F. Hoffmann-La Roche Ag |
Improved production cells
|
WO2023235848A1
(en)
|
2022-06-04 |
2023-12-07 |
Regeneron Pharmaceuticals, Inc. |
Interleukin-2 proproteins and uses thereof
|
WO2024003837A1
(en)
|
2022-06-30 |
2024-01-04 |
Janssen Biotech, Inc. |
Use of anti-egfr/anti-met antibody to treat gastric or esophageal cancer
|
WO2024020429A1
(en)
|
2022-07-22 |
2024-01-25 |
Lyell Immunopharma, Inc. |
Immune cell therapy
|
WO2024030976A2
(en)
|
2022-08-03 |
2024-02-08 |
Voyager Therapeutics, Inc. |
Compositions and methods for crossing the blood brain barrier
|
WO2024040247A1
(en)
|
2022-08-18 |
2024-02-22 |
Regeneron Pharmaceuticals, Inc. |
Interferon proproteins and uses thereof
|
US20240067691A1
(en)
|
2022-08-18 |
2024-02-29 |
Regeneron Pharmaceuticals, Inc. |
Interferon receptor agonists and uses thereof
|
TW202428602A
(zh)
|
2022-09-15 |
2024-07-16 |
美商航海家醫療公司 |
Tau結合化合物
|
WO2024077018A2
(en)
|
2022-10-04 |
2024-04-11 |
Alpine Immune Sciences, Inc. |
Methods and uses of taci-fc fusion immunomodulatory protein
|
TW202423969A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及蛋白酶體抑制劑之組合療法
|
TW202430211A
(zh)
|
2022-10-10 |
2024-08-01 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及imid之組合療法
|
TW202423970A
(zh)
|
2022-10-10 |
2024-06-16 |
瑞士商赫孚孟拉羅股份公司 |
Gprc5d tcb及cd38抗體之組合療法
|
WO2024079069A1
(en)
|
2022-10-12 |
2024-04-18 |
F. Hoffmann-La Roche Ag |
Method for classifying cells
|
WO2024084052A1
(en)
|
2022-10-21 |
2024-04-25 |
Novimmune Sa |
Pd-l1xcd28 bispecific antibodies for immune checkpoint-dependent t cell activation
|
WO2024089551A1
(en)
|
2022-10-25 |
2024-05-02 |
Janssen Biotech, Inc. |
Msln and cd3 binding agents and methods of use thereof
|
TW202432177A
(zh)
|
2022-10-31 |
2024-08-16 |
丹麥商珍美寶股份有限公司 |
Cd38抗體及其用途
|
WO2024095173A1
(en)
|
2022-11-02 |
2024-05-10 |
Janssen Biotech, Inc. |
Methods of treating cancers
|
WO2024094822A1
(en)
|
2022-11-02 |
2024-05-10 |
Genmab A/S |
Bispecific antibodies against cd3 and cd20 for treating richter's syndrome
|
WO2024100170A1
(en)
|
2022-11-11 |
2024-05-16 |
F. Hoffmann-La Roche Ag |
Antibodies binding to hla-a*02/foxp3
|
WO2024104933A1
(en)
|
2022-11-15 |
2024-05-23 |
F. Hoffmann-La Roche Ag |
Antigen binding molecules
|
WO2024104988A1
(en)
|
2022-11-15 |
2024-05-23 |
F. Hoffmann-La Roche Ag |
Recombinant binding proteins with activatable effector domain
|
WO2024119193A2
(en)
|
2022-12-02 |
2024-06-06 |
AskGene Pharma, Inc. |
Mutant il-2 polypeptides and il-2 prodrugs
|
WO2024130175A2
(en)
|
2022-12-16 |
2024-06-20 |
Regeneron Pharmaceuticals, Inc. |
Antigen-binding molecules that bind to aav particles and uses
|
US20240252601A1
(en)
|
2022-12-23 |
2024-08-01 |
Regeneron Pharmaceuticals, Inc. |
Ace2 fusion proteins and uses thereof
|
WO2024143442A1
(ja)
*
|
2022-12-27 |
2024-07-04 |
中外製薬株式会社 |
会合が制御されたポリペプチド
|
US20240270836A1
(en)
|
2023-01-13 |
2024-08-15 |
Regeneron Pharmaceuticals, Inc. |
Il12 receptor agonists and methods of use thereof
|
US20240247069A1
(en)
|
2023-01-13 |
2024-07-25 |
Regeneron Pharmaceuticals, Inc. |
Fgfr3 binding molecules and methods of use thereof
|
WO2024153725A1
(en)
|
2023-01-20 |
2024-07-25 |
F. Hoffmann-La Roche Ag |
Recombinant fc domain - il2 variant polypeptides and combination therapy with membrane-anchored antigen binding polypeptides
|
WO2024156672A1
(en)
|
2023-01-25 |
2024-08-02 |
F. Hoffmann-La Roche Ag |
Antibodies binding to csf1r and cd3
|
WO2024163494A1
(en)
|
2023-01-31 |
2024-08-08 |
F. Hoffmann-La Roche Ag |
Methods and compositions for treating non-small cell lung cancer and triple-negative breast cancer
|
WO2024163009A1
(en)
|
2023-01-31 |
2024-08-08 |
Genentech, Inc. |
Methods and compositions for treating urothelial bladder cancer
|
WO2024168061A2
(en)
|
2023-02-07 |
2024-08-15 |
Ayan Therapeutics Inc. |
Antibody molecules binding to sars-cov-2
|
WO2024166047A1
(en)
|
2023-02-09 |
2024-08-15 |
Janssen Biotech, Inc. |
Anti-v beta 17/anti-cd123 bispecific antibodies
|
US20240309072A1
(en)
|
2023-02-28 |
2024-09-19 |
Regeneron Pharmaceuticals, Inc. |
Multivalent anti-spike protein binding molecules and uses thereof
|
WO2024182540A2
(en)
|
2023-02-28 |
2024-09-06 |
Regeneron Pharmaceuticals, Inc. |
T cell activators and methods of use thereof
|
WO2024184287A1
(en)
|
2023-03-06 |
2024-09-12 |
F. Hoffmann-La Roche Ag |
Combination therapy of an anti-egfrviii/anti-cd3 antibody and an tumor-targeted 4-1bb agonist
|
WO2024189544A1
(en)
|
2023-03-13 |
2024-09-19 |
Janssen Biotech, Inc. |
Combination therapies with bi-specific anti-egfr/c-met antibodies and anti-pd-1 antibodies
|
WO2024188965A1
(en)
|
2023-03-13 |
2024-09-19 |
F. Hoffmann-La Roche Ag |
Combination therapy employing a pd1-lag3 bispecific antibody and an hla-g t cell bispecific antibody
|
WO2024208777A1
(en)
|
2023-04-03 |
2024-10-10 |
F. Hoffmann-La Roche Ag |
All-in-one agonistic antibodies
|
WO2024208776A1
(en)
|
2023-04-03 |
2024-10-10 |
F. Hoffmann-La Roche Ag |
Agonistic split antibodies
|
WO2024208898A1
(en)
|
2023-04-05 |
2024-10-10 |
Genmab A/S |
Pharmaceutical compositions comprising antibodies binding to cd30 and cd3
|
US20240368297A1
(en)
|
2023-04-13 |
2024-11-07 |
Genmab A/S |
Methods of treating lymphoma with bispecific antibodies against cd3 and cd20
|
US12116410B1
(en)
|
2023-12-26 |
2024-10-15 |
Medicovestor, Inc. |
Methods of manufacturing dimeric antibodies
|
US12121587B1
(en)
|
2023-12-26 |
2024-10-22 |
Medicovestor, Inc. |
Dimeric antibodies
|
GB202402048D0
(en)
|
2024-02-14 |
2024-03-27 |
Bivictrix Ltd |
Therapeutic antibodies
|