DK0599114T3 - Vitamin D3-analoge - Google Patents

Vitamin D3-analoge

Info

Publication number: DK0599114T3
Authority: DK; Denmark
Prior art keywords: vitamin; analog; hydrogen; diseases; acyl
Prior art date: 1992-11-20

Application number

DK93117951.9T

Other languages

English (en)

Inventor

Milan Radoje Uskokovic

Masami Okabe

Thomas I Doran

John Arthur Mclane

Michelangelo Scalone

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-11-20

Filing date

1993-11-05

Publication date

1997-04-14

1993-11-05 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1997-04-14 Application granted granted Critical

1997-04-14 Publication of DK0599114T3 publication Critical patent/DK0599114T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hematology (AREA)
Epidemiology (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Dermatology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK93117951.9T 1992-11-20 1993-11-05 Vitamin D3-analoge DK0599114T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US97913392A	1992-11-20	1992-11-20

Publications (1)

Publication Number	Publication Date
DK0599114T3 true DK0599114T3 (da)	1997-04-14

Family

ID=25526724

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK93117951.9T DK0599114T3 (da)	1992-11-20	1993-11-05	Vitamin D3-analoge

Country Status (25)

Country	Link
US (3)	US5342833A (da)
EP (1)	EP0599114B1 (da)
JP (2)	JP2502931B2 (da)
KR (1)	KR940011443A (da)
CN (1)	CN1051762C (da)
AT (1)	ATE147728T1 (da)
AU (1)	AU669222B2 (da)
BR (1)	BR9304780A (da)
CA (1)	CA2108848A1 (da)
CZ (1)	CZ284415B6 (da)
DE (1)	DE69307478T2 (da)
DK (1)	DK0599114T3 (da)
ES (1)	ES2097423T3 (da)
FI (1)	FI935092A (da)
GR (1)	GR3022691T3 (da)
HU (1)	HU213609B (da)
IL (1)	IL107614A (da)
NO (1)	NO304022B1 (da)
NZ (1)	NZ250194A (da)
PH (1)	PH30991A (da)
PL (1)	PL176017B1 (da)
RU (1)	RU2126385C1 (da)
TW (1)	TW267161B (da)
UY (1)	UY23678A1 (da)
ZA (1)	ZA938478B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA95906B (en) *	1994-02-07	1996-08-06	Res Developments Foundation	Non-viral vector
WO1997013518A1 (en) *	1995-10-10	1997-04-17	Marilyn Strube	Treatment of pruritus with vitamin d and analogs thereof
TW403735B (en) *	1995-11-22	2000-09-01	Hoffmann La Roche	25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
US5691328A (en) *	1996-02-02	1997-11-25	Clarion Pharmaceuticals Inc.	Phosphoethanolamine conjugates of vitamin D compounds
US5939408A (en)	1996-05-23	1999-08-17	Hoffman-La Roche Inc.	Vitamin D3 analogs
NO971934L (no) *	1996-05-23	1997-11-24	Hoffmann La Roche	Flourinerte vitamin D3 -analoger
EP0884308B1 (en) *	1997-05-02	2003-04-16	Duphar International Research B.V	A method of preparing 16-dehydro vitamin D compounds
US8404667B2 (en) *	2006-12-29	2013-03-26	Wisconsin Alumni Research Foundation	Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog
EP1812011A1 (en)	2004-11-12	2007-08-01	Bioxell S.p.a.	Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
KR101701382B1 (ko)	2014-01-29	2017-02-01	주식회사 휴메딕스	페길레이션된 7-디하이드로콜레스테롤 유도체
KR101702076B1 (ko)	2015-02-25	2017-02-02	주식회사 휴메딕스	지방산 컨쥬게이션된 7-데하이드로콜레스테롤 유도체

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3970676A (en) *	1974-10-29	1976-07-20	The Upjohn Company	Novel process and intermediate compounds used is preparation of -Δ5,7- steroid dienes
US4116985A (en) *	1976-07-26	1978-09-26	The Upjohn Company	Novel method for preparing cholesta-5,7-diene 3β,25-diol and derivatives thereof
US4360471A (en) *	1981-12-11	1982-11-23	Wisconsin Alumni Research Foundation	23-Dehydro-25-hydroxyvitamin D3
US4456553A (en) *	1982-05-07	1984-06-26	Teijin Limited	Vitamin D3 derivatives, process for preparation thereof, and antigens comprising said derivatives to be used for preparation of antibodies for immunochemical assay and antibodies prepared therefrom
US4448721A (en) *	1982-09-20	1984-05-15	Wisconsin Alumni Research Foundation	Hydroxyvitamin D2 compounds and process for preparing same
JPS63264452A (ja) *	1986-10-20	1988-11-01	Sumitomo Pharmaceut Co Ltd	フッ素化ビタミンｄ↓３誘導体
EP0321572B1 (en) *	1987-03-30	1993-06-09	Kuraray Co., Ltd.	Pregnane derivatives and process for their preparation
US4804502A (en) *	1988-01-20	1989-02-14	Hoffmann-La Roche Inc.	Vitamin D compounds
US5087619A (en) *	1988-01-20	1992-02-11	Hoffman-La Roche Inc.	Vitamin D3 analogs
ZA8923B (en) *	1988-01-20	1989-09-27	Hoffmann La Roche	16-dehydro-vitamin d3-derivatives
US5145846A (en) *	1988-01-20	1992-09-08	Hoffmann-La Roche Inc.	Vitamin D3 analogs
US5218109A (en) *	1988-07-05	1993-06-08	Kuraray Co., Ltd.	Steroid compounds
CA1333616C (en) *	1989-03-09	1994-12-20	Hector F. Deluca	19-nor-vitamin d compounds
US4973584A (en) *	1989-03-09	1990-11-27	Deluca Hector F	Novel 1α-hydroxyvitamin D2 epimer and derivatives
NZ232734A (en) *	1989-03-09	1991-11-26	Wisconsin Alumni Res Found	19-nor vitamin d derivatives and pharmaceutical compositions
DE69005897D1 (de) *	1989-05-18	1994-02-24	Hoffmann La Roche	Dehydrocholecalciferolderivate.
WO1991003246A1 (en) *	1989-09-11	1991-03-21	Wisconsin Alumni Research Foundation	Novel use of vitamin d compounds to inhibit replication of the aids virus
IL97158A (en) *	1990-02-06	1994-12-29	Schering Ag	Homologous histories of vitamin D in the side chain, processes for their preparation and pharmaceutical preparations containing them
DE4101953A1 (de) *	1991-01-19	1992-07-23	Schering Ag	23-oxa-derivate in der vitamin-d-reihe, verfahren zu ihrer herstellung diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
DE4105503A1 (de) *	1991-02-19	1992-08-20	Jenapharm Gmbh	Ausgangsverbindungen zur herstellung von calcitriol sowie dessen abkoemmlingen, verfahren zur herstellung dieser ausgangsverbindungen sowie zwischenprodukte fuer dieses verfahren
US5206230A (en) *	1991-06-05	1993-04-27	Daikin Industries, Ltd.	Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
DK0521550T3 (da) *	1991-07-05	1996-11-04	Duphar Int Res	Vitamin D forbindelse, fremgangsmåde til fremstilling af denne forbindelse og mellemprodukt derfor

1993
- 1993-10-15 TW TW082108572A patent/TW267161B/zh active
- 1993-10-20 CA CA002108848A patent/CA2108848A1/en not_active Abandoned
- 1993-11-05 EP EP93117951A patent/EP0599114B1/en not_active Expired - Lifetime
- 1993-11-05 ES ES93117951T patent/ES2097423T3/es not_active Expired - Lifetime
- 1993-11-05 AT AT93117951T patent/ATE147728T1/de not_active IP Right Cessation
- 1993-11-05 DK DK93117951.9T patent/DK0599114T3/da active
- 1993-11-05 DE DE69307478T patent/DE69307478T2/de not_active Expired - Fee Related
- 1993-11-12 ZA ZA938478A patent/ZA938478B/xx unknown
- 1993-11-12 PH PH47260A patent/PH30991A/en unknown
- 1993-11-15 IL IL10761493A patent/IL107614A/en not_active IP Right Cessation
- 1993-11-15 NZ NZ250194A patent/NZ250194A/en unknown
- 1993-11-15 AU AU50697/93A patent/AU669222B2/en not_active Ceased
- 1993-11-15 RU RU93052149A patent/RU2126385C1/ru active
- 1993-11-15 HU HU9303227A patent/HU213609B/hu not_active IP Right Cessation
- 1993-11-17 FI FI935092A patent/FI935092A/fi unknown
- 1993-11-17 JP JP5311371A patent/JP2502931B2/ja not_active Expired - Lifetime
- 1993-11-18 KR KR1019930024594A patent/KR940011443A/ko not_active Application Discontinuation
- 1993-11-19 UY UY23678A patent/UY23678A1/es not_active IP Right Cessation
- 1993-11-19 CN CN93114532A patent/CN1051762C/zh not_active Expired - Fee Related
- 1993-11-19 CZ CZ932489A patent/CZ284415B6/cs not_active IP Right Cessation
- 1993-11-19 BR BR9304780A patent/BR9304780A/pt not_active Application Discontinuation
- 1993-11-19 NO NO934197A patent/NO304022B1/no not_active IP Right Cessation
- 1993-11-19 PL PL93301103A patent/PL176017B1/pl unknown
- 1993-11-22 US US08/155,663 patent/US5342833A/en not_active Expired - Lifetime
1994
- 1994-06-07 US US08/255,012 patent/US5393900A/en not_active Expired - Lifetime
- 1994-11-23 US US08/344,421 patent/US5747478A/en not_active Expired - Lifetime
1995
- 1995-09-28 JP JP7273686A patent/JPH08109191A/ja active Pending
1997
- 1997-02-27 GR GR970400372T patent/GR3022691T3/el unknown

Also Published As

Publication number	Publication date
HU9303227D0 (en)	1994-03-28
PH30991A (en)	1997-12-23
KR940011443A (ko)	1994-06-21
NO934197D0 (no)	1993-11-19
JP2502931B2 (ja)	1996-05-29
US5342833A (en)	1994-08-30
CZ284415B6 (cs)	1998-11-11
TW267161B (da)	1996-01-01
JPH08109191A (ja)	1996-04-30
CZ248993A3 (en)	1994-06-15
CA2108848A1 (en)	1994-05-21
JPH06199777A (ja)	1994-07-19
NO304022B1 (no)	1998-10-12
HUT66022A (en)	1994-08-29
DE69307478D1 (de)	1997-02-27
UY23678A1 (es)	1994-05-20
ZA938478B (en)	1994-05-20
IL107614A (en)	1999-09-22
FI935092A (fi)	1994-05-21
EP0599114B1 (en)	1997-01-15
RU2126385C1 (ru)	1999-02-20
FI935092A0 (fi)	1993-11-17
CN1090573A (zh)	1994-08-10
ATE147728T1 (de)	1997-02-15
NO934197L (no)	1994-05-24
BR9304780A (pt)	1994-07-05
PL176017B1 (pl)	1999-03-31
US5747478A (en)	1998-05-05
EP0599114A1 (en)	1994-06-01
HU213609B (en)	1997-08-28
NZ250194A (en)	1996-01-26
GR3022691T3 (en)	1997-05-31
US5393900A (en)	1995-02-28
ES2097423T3 (es)	1997-04-01
DE69307478T2 (de)	1997-05-28
IL107614A0 (en)	1994-02-27
AU669222B2 (en)	1996-05-30
AU5069793A (en)	1994-06-02
PL301103A1 (en)	1994-05-30
CN1051762C (zh)	2000-04-26

Publication	Publication Date	Title
ATE74508T1 (de)	1992-04-15	Azithromycin und seine derivate als antiprotozoenmittel.
ATE215530T1 (de)	2002-04-15	7-substituierte-8-substituierte-9-substituierte amino-7-demethyl-6-deoxy-tetracycline als antibiotische mittel
ATE168992T1 (de)	1998-08-15	7-substituierte-9-substituierte glycylamido-6- demethyl-6-deoxytetracycline
TW269678B (da)	1996-02-01
NO951432D0 (no)	1995-04-12	Farmasöytiske preparater
DE3681358D1 (de)	1991-10-17	Substituierte oxindol-3-carboxamine als entzuendungshemmendes und schmerzstillendes mittel.
ATE141914T1 (de)	1996-09-15	Fluorierte analoge vitamins d3
ES2157992T3 (es)	2001-09-01	Alcoxi-alquil-carbamatos de imidazo(1,2-a)piridinas.
TW222638B (da)	1994-04-21
DK0599114T3 (da)	1997-04-14	Vitamin D3-analoge
IT1233753B (it)	1992-04-14	Composizioni farmaceutiche ad attivita' sulla microcircolazione cutanea.
ES2193218T3 (es)	2003-11-01	Combinacion de sustancias activas contra el acne y los comedones inflamados.
ATE183088T1 (de)	1999-08-15	Arzneimittel zur behandlung von hauterkrankungen
ATE153340T1 (de)	1997-06-15	Cyathane derivate und diese enthaltende nervenwachstumsfaktor produktion stimulatoren und antimikrobielle mittel
DE68921051D1 (de)	1995-03-23	Pyridin-3-percarboxylsäure monopersulfat.
ES2129053T3 (es)	1999-06-01	Nuevos derivados de fosfolipidos.