FI935092A - D3-vitaminanaloger - Google Patents

D3-vitaminanaloger Download PDF

Info

Publication number: FI935092A
Authority: FI; Finland
Prior art keywords: hydrogen; vitaminanaloger; diseases; acyl; chem
Prior art date: 1992-11-20

Application number

FI935092A

Other languages

English (en)

Other versions

FI935092A0 (fi

Inventor

Thomas I Doran

John Arthur Mclane

Masami Okabe

Michelangelo Scalone

Milan Radoje Uskokovic

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-11-20

Filing date

1993-11-17

Publication date

1994-05-21

1993-11-17 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1993-11-17 Publication of FI935092A0 publication Critical patent/FI935092A0/fi

1994-05-21 Publication of FI935092A publication Critical patent/FI935092A/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Obesity (AREA)
Nutrition Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

FI935092A 1992-11-20 1993-11-17 D3-vitaminanaloger FI935092A (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US97913392A	1992-11-20	1992-11-20

Publications (2)

Publication Number	Publication Date
FI935092A0 FI935092A0 (fi)	1993-11-17
FI935092A true FI935092A (fi)	1994-05-21

Family

ID=25526724

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI935092A FI935092A (fi)	1992-11-20	1993-11-17	D3-vitaminanaloger

Country Status (25)

Country	Link
US (3)	US5342833A (fi)
EP (1)	EP0599114B1 (fi)
JP (2)	JP2502931B2 (fi)
KR (1)	KR940011443A (fi)
CN (1)	CN1051762C (fi)
AT (1)	ATE147728T1 (fi)
AU (1)	AU669222B2 (fi)
BR (1)	BR9304780A (fi)
CA (1)	CA2108848A1 (fi)
CZ (1)	CZ284415B6 (fi)
DE (1)	DE69307478T2 (fi)
DK (1)	DK0599114T3 (fi)
ES (1)	ES2097423T3 (fi)
FI (1)	FI935092A (fi)
GR (1)	GR3022691T3 (fi)
HU (1)	HU213609B (fi)
IL (1)	IL107614A (fi)
NO (1)	NO304022B1 (fi)
NZ (1)	NZ250194A (fi)
PH (1)	PH30991A (fi)
PL (1)	PL176017B1 (fi)
RU (1)	RU2126385C1 (fi)
TW (1)	TW267161B (fi)
UY (1)	UY23678A1 (fi)
ZA (1)	ZA938478B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA95906B (en) *	1994-02-07	1996-08-06	Res Developments Foundation	Non-viral vector
JPH11514999A (ja) *	1995-10-10	1999-12-21	ストルーブ，マリリン	ビタミンｄおよびその誘導体による掻痒症治療
TW403735B (en) *	1995-11-22	2000-09-01	Hoffmann La Roche	25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
US5691328A (en) *	1996-02-02	1997-11-25	Clarion Pharmaceuticals Inc.	Phosphoethanolamine conjugates of vitamin D compounds
NO971934L (no) *	1996-05-23	1997-11-24	Hoffmann La Roche	Flourinerte vitamin D3 -analoger
US5939408A (en)	1996-05-23	1999-08-17	Hoffman-La Roche Inc.	Vitamin D3 analogs
DK0884308T3 (da) *	1997-05-02	2003-07-21	Duphar Int Res	Fremgangsmåde til at fremstille 16-dehydro vitamin D forbindelser
US8404667B2 (en) *	2006-12-29	2013-03-26	Wisconsin Alumni Research Foundation	Compounds, compositions, kits and methods of use to orally and topically treat acne and other skin conditions by 19-Nor vitamin D analog
US20080293647A1 (en)	2004-11-12	2008-11-27	Luciano Adorini	Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer
JP2017505778A (ja)	2014-01-29	2017-02-23	ヒューメディックスカンパニー，リミテッド	ペグ化７−デヒドロコレステロール誘導体
KR101702076B1 (ko)	2015-02-25	2017-02-02	주식회사 휴메딕스	지방산 컨쥬게이션된 7-데하이드로콜레스테롤 유도체

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3970676A (en) *	1974-10-29	1976-07-20	The Upjohn Company	Novel process and intermediate compounds used is preparation of -Δ5,7- steroid dienes
US4116985A (en) *	1976-07-26	1978-09-26	The Upjohn Company	Novel method for preparing cholesta-5,7-diene 3β,25-diol and derivatives thereof
US4360471A (en) *	1981-12-11	1982-11-23	Wisconsin Alumni Research Foundation	23-Dehydro-25-hydroxyvitamin D3
US4456553A (en) *	1982-05-07	1984-06-26	Teijin Limited	Vitamin D3 derivatives, process for preparation thereof, and antigens comprising said derivatives to be used for preparation of antibodies for immunochemical assay and antibodies prepared therefrom
US4448721A (en) *	1982-09-20	1984-05-15	Wisconsin Alumni Research Foundation	Hydroxyvitamin D2 compounds and process for preparing same
JPS63264452A (ja) *	1986-10-20	1988-11-01	Sumitomo Pharmaceut Co Ltd	フッ素化ビタミンｄ↓３誘導体
EP0321572B1 (en) *	1987-03-30	1993-06-09	Kuraray Co., Ltd.	Pregnane derivatives and process for their preparation
ZA8923B (en) *	1988-01-20	1989-09-27	Hoffmann La Roche	16-dehydro-vitamin d3-derivatives
US5087619A (en) *	1988-01-20	1992-02-11	Hoffman-La Roche Inc.	Vitamin D3 analogs
US5145846A (en) *	1988-01-20	1992-09-08	Hoffmann-La Roche Inc.	Vitamin D3 analogs
US4804502A (en) *	1988-01-20	1989-02-14	Hoffmann-La Roche Inc.	Vitamin D compounds
US5218109A (en) *	1988-07-05	1993-06-08	Kuraray Co., Ltd.	Steroid compounds
CA1333616C (en) *	1989-03-09	1994-12-20	Hector F. Deluca	19-nor-vitamin d compounds
US4973584A (en) *	1989-03-09	1990-11-27	Deluca Hector F	Novel 1α-hydroxyvitamin D2 epimer and derivatives
NZ232734A (en) *	1989-03-09	1991-11-26	Wisconsin Alumni Res Found	19-nor vitamin d derivatives and pharmaceutical compositions
DK0398217T3 (da) *	1989-05-18	1994-02-14	Hoffmann La Roche	Dehydrocholecalciferolderivater
AU6441890A (en) *	1989-09-11	1991-04-08	Wisconsin Alumni Research Foundation	Novel use of vitamin d compounds to inhibit replication of the aids virus
EP0441467B1 (de) *	1990-02-06	1994-06-01	Schering Aktiengesellschaft	Seitenketten-homologe Vitamin-D-Derivate, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate, sowie deren Verwendung als Arzneimittel
DE4101953A1 (de) *	1991-01-19	1992-07-23	Schering Ag	23-oxa-derivate in der vitamin-d-reihe, verfahren zu ihrer herstellung diese derivate enthaltende pharmazeutische praeparate sowie deren verwendung als arzneimittel
DE4105503A1 (de) *	1991-02-19	1992-08-20	Jenapharm Gmbh	Ausgangsverbindungen zur herstellung von calcitriol sowie dessen abkoemmlingen, verfahren zur herstellung dieser ausgangsverbindungen sowie zwischenprodukte fuer dieses verfahren
US5206230A (en) *	1991-06-05	1993-04-27	Daikin Industries, Ltd.	Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
DE69213844T2 (de) *	1991-07-05	1997-04-10	Duphar Int Res	Vitamin-D Derivat, Verfahren zu dessen Herstellung sowie Zwischenprodukte dafür

1993
- 1993-10-15 TW TW082108572A patent/TW267161B/zh active
- 1993-10-20 CA CA002108848A patent/CA2108848A1/en not_active Abandoned
- 1993-11-05 ES ES93117951T patent/ES2097423T3/es not_active Expired - Lifetime
- 1993-11-05 DK DK93117951.9T patent/DK0599114T3/da active
- 1993-11-05 DE DE69307478T patent/DE69307478T2/de not_active Expired - Fee Related
- 1993-11-05 AT AT93117951T patent/ATE147728T1/de not_active IP Right Cessation
- 1993-11-05 EP EP93117951A patent/EP0599114B1/en not_active Expired - Lifetime
- 1993-11-12 PH PH47260A patent/PH30991A/en unknown
- 1993-11-12 ZA ZA938478A patent/ZA938478B/xx unknown
- 1993-11-15 HU HU9303227A patent/HU213609B/hu not_active IP Right Cessation
- 1993-11-15 RU RU93052149A patent/RU2126385C1/ru active
- 1993-11-15 NZ NZ250194A patent/NZ250194A/en unknown
- 1993-11-15 AU AU50697/93A patent/AU669222B2/en not_active Ceased
- 1993-11-15 IL IL10761493A patent/IL107614A/en not_active IP Right Cessation
- 1993-11-17 JP JP5311371A patent/JP2502931B2/ja not_active Expired - Lifetime
- 1993-11-17 FI FI935092A patent/FI935092A/fi unknown
- 1993-11-18 KR KR1019930024594A patent/KR940011443A/ko not_active Application Discontinuation
- 1993-11-19 NO NO934197A patent/NO304022B1/no not_active IP Right Cessation
- 1993-11-19 CN CN93114532A patent/CN1051762C/zh not_active Expired - Fee Related
- 1993-11-19 BR BR9304780A patent/BR9304780A/pt not_active Application Discontinuation
- 1993-11-19 PL PL93301103A patent/PL176017B1/pl unknown
- 1993-11-19 CZ CZ932489A patent/CZ284415B6/cs not_active IP Right Cessation
- 1993-11-19 UY UY23678A patent/UY23678A1/es not_active IP Right Cessation
- 1993-11-22 US US08/155,663 patent/US5342833A/en not_active Expired - Lifetime
1994
- 1994-06-07 US US08/255,012 patent/US5393900A/en not_active Expired - Lifetime
- 1994-11-23 US US08/344,421 patent/US5747478A/en not_active Expired - Lifetime
1995
- 1995-09-28 JP JP7273686A patent/JPH08109191A/ja active Pending
1997
- 1997-02-27 GR GR970400372T patent/GR3022691T3/el unknown

Also Published As

Publication number	Publication date
NO934197L (no)	1994-05-24
HU213609B (en)	1997-08-28
UY23678A1 (es)	1994-05-20
PL301103A1 (en)	1994-05-30
RU2126385C1 (ru)	1999-02-20
JP2502931B2 (ja)	1996-05-29
US5342833A (en)	1994-08-30
PL176017B1 (pl)	1999-03-31
ES2097423T3 (es)	1997-04-01
NO304022B1 (no)	1998-10-12
DE69307478T2 (de)	1997-05-28
US5393900A (en)	1995-02-28
BR9304780A (pt)	1994-07-05
HU9303227D0 (en)	1994-03-28
KR940011443A (ko)	1994-06-21
TW267161B (fi)	1996-01-01
CA2108848A1 (en)	1994-05-21
ATE147728T1 (de)	1997-02-15
CZ284415B6 (cs)	1998-11-11
GR3022691T3 (en)	1997-05-31
JPH06199777A (ja)	1994-07-19
US5747478A (en)	1998-05-05
CN1090573A (zh)	1994-08-10
IL107614A (en)	1999-09-22
CN1051762C (zh)	2000-04-26
IL107614A0 (en)	1994-02-27
JPH08109191A (ja)	1996-04-30
AU5069793A (en)	1994-06-02
EP0599114A1 (en)	1994-06-01
DK0599114T3 (da)	1997-04-14
NO934197D0 (no)	1993-11-19
FI935092A0 (fi)	1993-11-17
ZA938478B (en)	1994-05-20
NZ250194A (en)	1996-01-26
AU669222B2 (en)	1996-05-30
PH30991A (en)	1997-12-23
HUT66022A (en)	1994-08-29
DE69307478D1 (de)	1997-02-27
CZ248993A3 (en)	1994-06-15
EP0599114B1 (en)	1997-01-15

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ATE168992T1 (de)	1998-08-15	7-substituierte-9-substituierte glycylamido-6- demethyl-6-deoxytetracycline
ATE215530T1 (de)	2002-04-15	7-substituierte-8-substituierte-9-substituierte amino-7-demethyl-6-deoxy-tetracycline als antibiotische mittel
TW269678B (fi)	1996-02-01
ATE74508T1 (de)	1992-04-15	Azithromycin und seine derivate als antiprotozoenmittel.
NO990542L (no)	1999-02-05	K-252a-derivater og anvendelse av K-252a-derivater
ATE67185T1 (de)	1991-09-15	Substituierte oxindol-3-carboxamine als entzuendungshemmendes und schmerzstillendes mittel.
ATE141914T1 (de)	1996-09-15	Fluorierte analoge vitamins d3
TW222638B (fi)	1994-04-21
ES2157992T3 (es)	2001-09-01	Alcoxi-alquil-carbamatos de imidazo(1,2-a)piridinas.
FI935092A0 (fi)	1993-11-17	D3-vitaminanaloger
NO903148L (no)	1991-01-15	Hemoreguleringspeptider.
IT1271567B (it)	1997-05-30	Procedimento per l'ulteriore trattamento di salcicce
DE68921051D1 (de)	1995-03-23	Pyridin-3-percarboxylsäure monopersulfat.
UA26077C2 (uk)	1999-04-30	Аплікаційhий матеріал лікувальhо-профілактичhого призhачеhhя
GR3020597T3 (en)	1996-10-31	Phospholipids for the treatment of multiple sclerosis