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RS64925B1 - Himerni antigenski receptori koji ciljaju bcma i postupci njihove upotrebe - Google Patents

Himerni antigenski receptori koji ciljaju bcma i postupci njihove upotrebe

Info

Publication number
RS64925B1
RS64925B1 RS20231139A RSP20231139A RS64925B1 RS 64925 B1 RS64925 B1 RS 64925B1 RS 20231139 A RS20231139 A RS 20231139A RS P20231139 A RSP20231139 A RS P20231139A RS 64925 B1 RS64925 B1 RS 64925B1
Authority
RS
Serbia
Prior art keywords
methods
chimeric antigen
antigen receptors
targeting bcma
receptors targeting
Prior art date
Application number
RS20231139A
Other languages
English (en)
Inventor
Xiaohu Fan
Qiuchuan Zhuang
Pingyan Wang
Lin Wang
Lei Yang
Jiaying Hao
Dan Zhao
Xian He
Original Assignee
Legend Biotech Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Legend Biotech Ireland Ltd filed Critical Legend Biotech Ireland Ltd
Publication of RS64925B1 publication Critical patent/RS64925B1/sr

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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
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    • A61K2239/27Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by targeting or presenting multiple antigens
    • A61K2239/29Multispecific CARs
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    • A61K2239/46Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
    • A61K2239/48Blood cells, e.g. leukemia or lymphoma
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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RS20231139A 2015-08-11 2017-08-10 Himerni antigenski receptori koji ciljaju bcma i postupci njihove upotrebe RS64925B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201510490002 2015-08-11
PCT/CN2016/094408 WO2017025038A1 (en) 2015-08-11 2016-08-10 Chimeric antigen receptors based on single-domain antibodies and methods of use thereof
EP21166662.3A EP3896091B1 (en) 2015-08-11 2017-08-10 Chimeric antigen receptors targeting bcma and methods of use thereof

Publications (1)

Publication Number Publication Date
RS64925B1 true RS64925B1 (sr) 2023-12-29

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Application Number Title Priority Date Filing Date
RS20240831A RS65866B1 (sr) 2015-08-11 2016-08-10 Himerni antigen receptori bazirani na jednodomenskim antitelima i postupci njihove upotrebe
RS20231139A RS64925B1 (sr) 2015-08-11 2017-08-10 Himerni antigenski receptori koji ciljaju bcma i postupci njihove upotrebe

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Application Number Title Priority Date Filing Date
RS20240831A RS65866B1 (sr) 2015-08-11 2016-08-10 Himerni antigen receptori bazirani na jednodomenskim antitelima i postupci njihove upotrebe

Country Status (32)

Country Link
US (5) US10934363B2 (sr)
EP (7) EP3334765A4 (sr)
JP (7) JP6859347B2 (sr)
KR (5) KR20180035918A (sr)
CN (9) CN105384825B (sr)
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