[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

FR2775188B1 - Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption - Google Patents

Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption

Info

Publication number
FR2775188B1
FR2775188B1 FR9802143A FR9802143A FR2775188B1 FR 2775188 B1 FR2775188 B1 FR 2775188B1 FR 9802143 A FR9802143 A FR 9802143A FR 9802143 A FR9802143 A FR 9802143A FR 2775188 B1 FR2775188 B1 FR 2775188B1
Authority
FR
France
Prior art keywords
promoting agent
absorption promoting
oral extended
galenic form
immediate release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9802143A
Other languages
English (en)
Other versions
FR2775188A1 (fr
Inventor
Olivier Saslawski
Philippe Giet
Dominique Michel
Thierry Hulot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sante SAS
Original Assignee
LIPHA SAS
LIPHA Liyonnaise Industrielle Pharmaceutique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9802143A priority Critical patent/FR2775188B1/fr
Application filed by LIPHA SAS, LIPHA Liyonnaise Industrielle Pharmaceutique filed Critical LIPHA SAS
Priority to PCT/EP1999/000994 priority patent/WO1999042086A1/fr
Priority to DK04001294T priority patent/DK1410791T3/da
Priority to EP04001294A priority patent/EP1410791B1/fr
Priority to SK1255-2000A priority patent/SK285188B6/sk
Priority to CA002321267A priority patent/CA2321267C/fr
Priority to PL342162A priority patent/PL191415B1/pl
Priority to KR1020007009307A priority patent/KR100587181B1/ko
Priority to AT99913165T priority patent/ATE268164T1/de
Priority to SI9930637T priority patent/SI1056445T1/xx
Priority to EP99913165A priority patent/EP1056445B1/fr
Priority to BR9908121-0A priority patent/BR9908121A/pt
Priority to SK5107-2005A priority patent/SK286248B6/sk
Priority to JP2000532103A priority patent/JP4828020B2/ja
Priority to IDW20001870A priority patent/ID26022A/id
Priority to US09/622,663 priority patent/US6426087B1/en
Priority to DE69917750T priority patent/DE69917750T2/de
Priority to RU2000124535/15A priority patent/RU2228201C2/ru
Priority to PT04001294T priority patent/PT1410791E/pt
Priority to APAP/P/2000/001943A priority patent/AP2000001943A0/en
Priority to AT04001294T priority patent/ATE408399T1/de
Priority to CZ20002940A priority patent/CZ299366B6/cs
Priority to CNB998032182A priority patent/CN1182837C/zh
Priority to AU31408/99A priority patent/AU750785B2/en
Priority to PT99913165T priority patent/PT1056445E/pt
Priority to PL377398A priority patent/PL201851B1/pl
Priority to HU0100970A priority patent/HU226732B1/hu
Priority to ES99913165T priority patent/ES2222695T3/es
Priority to SI9931019T priority patent/SI1410791T1/sl
Priority to DK99913165T priority patent/DK1056445T3/da
Priority to ES04001294T priority patent/ES2314302T3/es
Priority to DE69939605T priority patent/DE69939605D1/de
Priority to ZA9901408A priority patent/ZA991408B/xx
Priority to ARP990100731A priority patent/AR018109A1/es
Publication of FR2775188A1 publication Critical patent/FR2775188A1/fr
Priority to NO20004190A priority patent/NO20004190L/no
Priority to OA1200000231A priority patent/OA11454A/en
Publication of FR2775188B1 publication Critical patent/FR2775188B1/fr
Application granted granted Critical
Priority to HK01105794A priority patent/HK1035142A1/xx
Priority to US10/100,084 priority patent/US6514524B1/en
Priority to ARP080102354A priority patent/AR066843A2/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Addiction (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR9802143A 1998-02-23 1998-02-23 Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption Expired - Fee Related FR2775188B1 (fr)

Priority Applications (39)

Application Number Priority Date Filing Date Title
FR9802143A FR2775188B1 (fr) 1998-02-23 1998-02-23 Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption
CNB998032182A CN1182837C (zh) 1998-02-23 1999-02-16 包含吸收促进剂的可口服给药的即释和缓释盖仑制剂以及吸收促进剂的用途
EP04001294A EP1410791B1 (fr) 1998-02-23 1999-02-16 Forme galénique administrable oralement comprenant de la metformine et un agent favorisant l'absorption
DK04001294T DK1410791T3 (da) 1998-02-23 1999-02-16 Oralt administrerbar galenisk form der omfatter metformin og et absorptionsfremmende middel
CA002321267A CA2321267C (fr) 1998-02-23 1999-02-16 Forme galenique s'administrant par voie orale, a liberation immediate et prolongee, et comprenant un agent favorisant l'absorption et utilisation de cet agent
PL342162A PL191415B1 (pl) 1998-02-23 1999-02-16 Forma galenowa do podawania doustnego o natychmiastowym i przedłużonym uwalnianiu leku, zawierająca środek wspomagający absorpcję oraz zastosowanie środka wspomagającego absorpcję
KR1020007009307A KR100587181B1 (ko) 1998-02-23 1999-02-16 흡수 촉진제를 포함하는 경구 투여가능한 속방성 및서방성 생약 형태 및 그 흡수 촉진제의 용도
AT99913165T ATE268164T1 (de) 1998-02-23 1999-02-16 Oral verabreichbare galenische form mit rascher freisetzung und mit verzögerter freisetzung, enthaltend ein absorbtionspromoter und verwendung dieses absorbtionspromoters
SI9930637T SI1056445T1 (en) 1998-02-23 1999-02-16 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent
EP99913165A EP1056445B1 (fr) 1998-02-23 1999-02-16 Forme galenique s'administrant par voie orale, a liberation immediate et prolongee, et comprenant un agent favorisant l'absorption et utilisation de cet agent
BR9908121-0A BR9908121A (pt) 1998-02-23 1999-02-16 Forma galênica de liberação imediata e de liberação prolongada administrável por via oral compreendendo um agente estimulador de absorção e utilização deste agente estimulador de absorção
SK5107-2005A SK286248B6 (sk) 1998-02-23 1999-02-16 Galenická formulácia na orálne podávanie, spôsob jej prípravy a použitie činidla podporujúceho absorpciu na jej prípravu
JP2000532103A JP4828020B2 (ja) 1998-02-23 1999-02-16 経口投与可能な吸収促進剤を含む即時遊離且つ延長遊離剤形およびこの吸収促進剤の使用
IDW20001870A ID26022A (id) 1998-02-23 1999-02-16 Bentuk galenic pelepasan yang telah diperpanjang dan pelepasan lanjutan yang terdiri dari bahan peningkat absorpsi yang dapat diberikan melalui mulut dan penggunaan bahan peningkat absorpsi tersebut
US09/622,663 US6426087B1 (en) 1998-02-23 1999-02-16 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent
AU31408/99A AU750785B2 (en) 1998-02-23 1999-02-16 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent
RU2000124535/15A RU2228201C2 (ru) 1998-02-23 1999-02-16 Вводимая оральным путем галенова форма с быстрым высвобождением и с пролонгированным высвобождением, включающая усиливающий абсорбцию агент, и применение этого усиливающего абсорбцию агента
PT04001294T PT1410791E (pt) 1998-02-23 1999-02-16 Forma galénica apta a ser administrada oralmente compreendendo metformina e um agente promotor da absorção
APAP/P/2000/001943A AP2000001943A0 (en) 1998-02-23 1999-02-16 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent.
AT04001294T ATE408399T1 (de) 1998-02-23 1999-02-16 Oral verabreichbare galenische form enthaltend metformin und einen absorptionspromoter
PCT/EP1999/000994 WO1999042086A1 (fr) 1998-02-23 1999-02-16 Forme galenique s'administrant par voie orale, a liberation immediate et prolongee, et comprenant un agent favorisant l'absorption et utilisation de cet agent
SK1255-2000A SK285188B6 (sk) 1998-02-23 1999-02-16 Galenická formulácia na orálne podávanie, spôsob jej prípravy a použitie činidla podporujúceho absorpciu na jej prípravu
DE69917750T DE69917750T2 (de) 1998-02-23 1999-02-16 Oral verabreichbare galenische form mit rascher freisetzung und mit verzögerter freisetzung, enthaltend ein absorbtionspromoter und verwendung dieses absorbtionspromoters
PT99913165T PT1056445E (pt) 1998-02-23 1999-02-16 Orcao forma galenica de libertacao imediata e de libertacao prolongada administravel oralmente compreendendo um agente promotor da absorcao e utilizacao deste agentepromotor da abs
PL377398A PL201851B1 (pl) 1998-02-23 1999-02-16 Forma galenowa do podawania doustnego o natychmiastowym i przedłużonym uwalnianiu leku, zawierająca środek wspomagający absorpcję oraz zastosowanie środka wspomagającego absorpcję
HU0100970A HU226732B1 (en) 1998-02-23 1999-02-16 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent
ES99913165T ES2222695T3 (es) 1998-02-23 1999-02-16 Forma galenica de liberacion inmediata y prolongada administrable por via oral que comprende un agente promotor de la absorcion y uso de dicho agente promotor de la absorcion.
SI9931019T SI1410791T1 (sl) 1998-02-23 1999-02-16 Peroralna galenska oblika, ki obsega metformin insredstvo za pospeĺ evanje absorpcije
DK99913165T DK1056445T3 (da) 1998-02-23 1999-02-16 Oralt administrerbar immediate-release- og prolinged-release- galenisk form omfattende et absorpsionsfremmende middel og anvendelse af dette absorpsionsfremmende middel
ES04001294T ES2314302T3 (es) 1998-02-23 1999-02-16 Forma galenica, oralmente administrable, que comprende metformina y unagente favorecedor de la absorcion.
DE69939605T DE69939605D1 (de) 1998-02-23 1999-02-16 Oral verabreichbare galenische Form enthaltend Metformin und einen Absorptionspromoter
CZ20002940A CZ299366B6 (cs) 1998-02-23 1999-02-16 Galenická forma k orálnímu podávání s okamžitým aprodlouženým uvolnováním, obsahující cinidlo podporující absorpci a použití tohoto absorpci podporujícího cinidla
ZA9901408A ZA991408B (en) 1998-02-23 1999-02-22 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent.
ARP990100731A AR018109A1 (es) 1998-02-23 1999-02-23 FORMULACIoN GALÉNICA ADMINISTRABLE POR VíA ORAL QUE PERMITE UNA ABSORCIoN MEJORADA DE PRINCIPIOS ACTIVOS, USO DE UN AGENTE MAJORADOR DE ABSORCIoN PARA PREPARAR UNA FORMA DE DOSIFICACIoN ADMINISTRABLE POR VíA ORAL Y PROCEDIMIENTO PARA PREPARAR DICHA FORMULACIoN GALÉNICA
NO20004190A NO20004190L (no) 1998-02-23 2000-08-22 Oralt administrerbar galenisk form med umiddelbar frigivelse og langvarig frigivelse som omfatter et absorpsjonsfremmende middel, og anvendelse av dette absorpsjonsfremmende middel
OA1200000231A OA11454A (en) 1998-02-23 2000-08-22 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent.
HK01105794A HK1035142A1 (en) 1998-02-23 2001-08-17 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent.
US10/100,084 US6514524B1 (en) 1998-02-23 2002-03-19 Orally administerable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent
ARP080102354A AR066843A2 (es) 1998-02-23 2008-06-04 Formulacion galenica administrable por via oral que permite una absorcion mejorada de principios activos, uso de un agente mejorador de la absorcion para preparar una forma de dosificacion administrable por via oral y procedimiento para preparar dicha formulacion galenica

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9802143A FR2775188B1 (fr) 1998-02-23 1998-02-23 Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption

Publications (2)

Publication Number Publication Date
FR2775188A1 FR2775188A1 (fr) 1999-08-27
FR2775188B1 true FR2775188B1 (fr) 2001-03-09

Family

ID=9523244

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9802143A Expired - Fee Related FR2775188B1 (fr) 1998-02-23 1998-02-23 Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption

Country Status (28)

Country Link
US (2) US6426087B1 (fr)
EP (2) EP1410791B1 (fr)
JP (1) JP4828020B2 (fr)
KR (1) KR100587181B1 (fr)
CN (1) CN1182837C (fr)
AP (1) AP2000001943A0 (fr)
AR (2) AR018109A1 (fr)
AT (2) ATE268164T1 (fr)
AU (1) AU750785B2 (fr)
BR (1) BR9908121A (fr)
CA (1) CA2321267C (fr)
CZ (1) CZ299366B6 (fr)
DE (2) DE69939605D1 (fr)
DK (2) DK1056445T3 (fr)
ES (2) ES2314302T3 (fr)
FR (1) FR2775188B1 (fr)
HK (1) HK1035142A1 (fr)
HU (1) HU226732B1 (fr)
ID (1) ID26022A (fr)
NO (1) NO20004190L (fr)
OA (1) OA11454A (fr)
PL (2) PL201851B1 (fr)
PT (2) PT1056445E (fr)
RU (1) RU2228201C2 (fr)
SI (2) SI1056445T1 (fr)
SK (2) SK285188B6 (fr)
WO (1) WO1999042086A1 (fr)
ZA (1) ZA991408B (fr)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9925127D0 (en) * 1999-10-22 1999-12-22 Pharmacia & Upjohn Spa Oral formulations for anti-tumor compounds
FR2805462B1 (fr) * 2000-02-24 2003-08-15 Therabel Res Nouvelle forme galenique orale a liberation prolongee de la molsidomine
DE10026699A1 (de) 2000-05-30 2001-12-06 Basf Ag Formulierung auf Heparin-, Glycosaminoglycan- oder Heparinoidbasis und Verwendung der Formulierung sowie der Formulierungsgrundlage
US7183410B2 (en) * 2001-08-02 2007-02-27 Bidachem S.P.A. Stable polymorph of flibanserin
US20030060475A1 (en) * 2001-08-10 2003-03-27 Boehringer Ingelheim Pharma Kg Method of using flibanserin for neuroprotection
UA78974C2 (en) * 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
SE0200475D0 (sv) * 2002-02-15 2002-02-15 Ltp Lipid Technologies Provide Oral farmaceutisk beredning
CA2481313A1 (fr) 2002-04-12 2003-10-23 Merck & Co., Inc. Amides bicycliques
US20040048877A1 (en) * 2002-05-22 2004-03-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions containing flibanserin
US10004729B2 (en) 2002-07-05 2018-06-26 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
JP2006502228A (ja) * 2002-10-07 2006-01-19 カイロン コーポレイション Ｈｉｖワクチン処方物
US20040151769A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Film coated tablet containing an extract of red vine leaves
ITRM20030074A1 (it) * 2003-02-21 2004-08-22 Pharmacia Italia Spa Formulazioni semisolide a rilascio immediato intese
US20040241252A1 (en) * 2003-05-29 2004-12-02 Abney Christopher Charles Pharmaceutical compositions for oral administration comprising lithium carbonate, processes of making the same, and methods of administering the same
WO2005060942A1 (fr) * 2003-12-19 2005-07-07 Aurobindo Pharma Ltd Composition pharmaceutique de metformine a liberation prolongee
WO2005102342A1 (fr) * 2004-04-22 2005-11-03 Boehringer Ingelheim International Gmbh Nouvelles compositions pharmaceutiques destinees au traitement de troubles sexuels ii
US20050239798A1 (en) * 2004-04-22 2005-10-27 Boehringer Ingelheim Pharmaceuticals, Inc. Method for the treatment of premenstrual and other female sexual disorders
WO2005123134A2 (fr) * 2004-05-14 2005-12-29 Cadila Healthcare Limited Systeme d'administration a liberation controlee pour metformine
CA2916869A1 (fr) 2004-06-12 2005-12-29 Jane C. Hirsh Formulations de prevention des abus
US20060024370A1 (en) * 2004-07-29 2006-02-02 Cephalon France Modafinil oral lyophilizate
US20060025420A1 (en) * 2004-07-30 2006-02-02 Boehringer Ingelheimn International GmbH Pharmaceutical compositions for the treatment of female sexual disorders
JP2008511569A (ja) * 2004-09-03 2008-04-17 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 注意欠如活動過多障害の治療方法
DE602005026833D1 (de) * 2004-10-01 2011-04-21 Firmenich & Cie Parfümierende oder aromastoffabsondernde mikrokapseln mit einem explosionsunterdrücker
CA2599721A1 (fr) * 2005-03-04 2006-09-14 Boehringer Ingelheim International Gmbh Compositions pharmaceutiques utiles dans le traitement et/ou la prevention de la depression
WO2006096439A2 (fr) * 2005-03-04 2006-09-14 Boehringer Ingelheim International Gmbh Compositions pharmaceutiques destinees au traitement et/ou a la prevention de la schizophrenie et de maladies associees
US20060199805A1 (en) * 2005-03-04 2006-09-07 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders
UY29445A1 (es) * 2005-03-30 2006-10-02 Generex Pharm Inc Composiciones para la transmisión transmucosa oral de la metformina
CA2608249A1 (fr) * 2005-05-06 2006-11-16 Boehringer Ingelheim International Gmbh Methode de traitement de la toxicomanie
CA2608363A1 (fr) * 2005-05-19 2006-11-23 Boehringer Ingelheim International Gmbh Procede pour le traitement de dysfonctionnements sexuels d'origine medicamenteuse
JP2008540672A (ja) * 2005-05-19 2008-11-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 病状に起因する性的機能不全の治療方法
ATE428416T1 (de) * 2005-06-21 2009-05-15 Merck Patent Gmbh Feste pharmazeutische zubereitung enthaltend (r)- (-)-2-ä5-(4-fluorophenyl)-3- pyridylmethylaminomethylü-chroman
EP1745788A1 (fr) * 2005-07-22 2007-01-24 KTB Tumorforschungsgesellschaft mbH Acylglycerophospholipides pour le traitement du cancer et de la cachexie
EP1912650B8 (fr) 2005-08-03 2017-10-18 Sprout Pharmaceuticals, Inc. Utilisation de la flibansérine dans le traitement de l'obésité
WO2007048803A1 (fr) * 2005-10-29 2007-05-03 Boehringer Ingelheim International Gmbh Derives de benzimidazolone utiles pour le traitement des troubles premenstruels et d'autres troubles sexuels chez la femme
US20070123540A1 (en) * 2005-10-29 2007-05-31 Angelo Ceci Sexual desire enhancing medicaments comprising benzimidazolone derivatives
US20070105869A1 (en) * 2005-11-08 2007-05-10 Stephane Pollentier Use of flibanserin for the treatment of pre-menopausal sexual desire disorders
WO2007106957A1 (fr) * 2006-03-21 2007-09-27 Laboratoires Smb S.A. Formes galéniques flottantes multiples à libération contrôlée
HUE026156T2 (en) * 2006-05-09 2016-06-28 Sprout Pharmaceuticals Inc The use of Flibanserin for the treatment of sexual desire after menopause
ATE456369T1 (de) 2006-06-30 2010-02-15 Boehringer Ingelheim Int Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen
CA2657043A1 (fr) * 2006-07-14 2008-01-17 Boehringer Ingelheim International Gmbh Utilisation de flibanserine pour le traitement de troubles sexuels chez les femmes
CL2007002214A1 (es) * 2006-08-14 2008-03-07 Boehringer Ingelheim Int Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp
CA2660476C (fr) * 2006-08-14 2015-11-17 Boehringer Ingelheim International Gmbh Formulations de flibanserine et leur procede de fabrication
BRPI0716436B8 (pt) * 2006-08-25 2021-05-25 Boehringer Ingelheim Int sistema de liberação controlada e método para fabricação do mesmo
US20080081142A1 (en) * 2006-10-03 2008-04-03 Zeik Douglas B Articles and methods for applying color on surfaces
EP1952803A1 (fr) * 2007-01-23 2008-08-06 KTB-Tumorforschungs GmbH Composition pharmaceutique solide contenant des phospholipides hydrogénés
WO2009033061A1 (fr) * 2007-09-07 2009-03-12 Xenoport, Inc. Promédicaments d'acamprosate à libération par cyclisation sous forme de néopentyl-sulfonylesters carboxylates masqués, compositions les comprenant et méthodes d'utilisation correspondantes
US20090082464A1 (en) * 2007-09-07 2009-03-26 Bernd Jandeleit Externally masked neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use
UY31335A1 (es) * 2007-09-12 2009-04-30 Tratamiento de sintomas vasomotores
EP2042165A1 (fr) * 2007-09-28 2009-04-01 Swiss Caps Rechte und Lizenzen AG Capsules molles remplies avec un excipient thermofusible
TW200932734A (en) * 2007-10-15 2009-08-01 Xenoport Inc Internally masked neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use
CA2638240C (fr) * 2008-08-29 2010-02-02 Alexander Macgregor Methode de traitement des anomalies de la glycemie et des variations de la glycemie
CA2750421C (fr) 2008-11-27 2016-10-18 B.R.A.I.N. Biotechnology Research And Information Network Ag Proteines tensioactives en tant qu'excipients dans des formulations pharmaceutiques solides
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
DK2512455T3 (en) 2009-12-18 2014-03-24 Frieslandcampina Nederland Holding B V Co-treated tablet adjuvant composition, its preparation and use
JP5546900B2 (ja) * 2010-02-25 2014-07-09 ライオン株式会社 パナキサトリオール安定化組成物
US9000046B2 (en) * 2010-09-28 2015-04-07 Depomed, Inc. Gastric retentive dosage forms for extended release of acamprosate into the upper gastrointestinal tract
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
RU2671399C2 (ru) * 2011-12-02 2018-10-31 Синкроньюэрон Инк. Композиции акампросата, способы их применения и содержащие их комбинации
KR102121404B1 (ko) * 2013-03-15 2020-06-11 썬 파마 글로벌 에프제트이 아비라테론 아세테이트 제제
US20150246060A1 (en) 2013-03-15 2015-09-03 Iceutica Inc. Abiraterone Acetate Formulation and Methods of Use
EP3878445A3 (fr) 2013-06-05 2021-10-27 Synchroneuron Inc. Formulations d'acamprosate, leurs procédés d'utilisation et combinaisons les comprenant
US20150157646A1 (en) 2013-09-27 2015-06-11 Iceutica Inc. Abiraterone Steroid Formulation
WO2017222575A1 (fr) 2016-06-23 2017-12-28 Collegium Pharmaceutical, Inc. Procédé de préparation de formulations orales dissuasives d'abus plus stables
CA3062834A1 (fr) 2017-05-17 2018-11-22 Confluence Pharmaceuticals, Llc Formulations d'homotaurines et de leurs sels
WO2023025672A1 (fr) 2021-08-25 2023-03-02 Basf Se Composition auxiliaire de compression directe

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI63335B (fi) * 1979-02-02 1983-02-28 Orion Yhtymae Oy Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne
FR2457281A1 (fr) * 1979-05-23 1980-12-19 Meram Lab Nouveaux derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee
GB8524421D0 (en) * 1985-10-03 1985-11-06 Boots Co Plc Therapeutic agents
JPS62265226A (ja) * 1986-05-12 1987-11-18 Fujisawa Pharmaceut Co Ltd 経口投与用製剤
ZA898331B (en) * 1988-11-22 1990-07-25 Hoffmann La Roche Pharmaceutical compositions
US5190748A (en) * 1988-11-22 1993-03-02 Hoffmann-La Roche Inc. Absorption enhancement of antibiotics
US5139786A (en) * 1989-07-07 1992-08-18 Ciba-Geigy Corporation Topical formulations
JPH03275633A (ja) * 1990-03-23 1991-12-06 Teikoku Seiyaku Co Ltd 生理活性ポリペプチドの吸収促進剤
US5138786A (en) 1991-07-17 1992-08-18 Fischer Michael G Insta-guard firearm protection
IT1255895B (it) * 1992-10-20 1995-11-17 Laura Chiodini Composizioni farmaceutiche contenenti una calcitonina
DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
US5858398A (en) * 1994-11-03 1999-01-12 Isomed Inc. Microparticular pharmaceutical compositions
GB9516268D0 (en) * 1995-08-08 1995-10-11 Danbiosyst Uk Compositiion for enhanced uptake of polar drugs from the colon

Also Published As

Publication number Publication date
PT1410791E (pt) 2008-12-24
PL201851B1 (pl) 2009-05-29
AR066843A2 (es) 2009-09-16
BR9908121A (pt) 2000-10-24
ZA991408B (en) 1999-08-23
DE69917750D1 (de) 2004-07-08
HK1035142A1 (en) 2001-11-16
US6426087B1 (en) 2002-07-30
JP4828020B2 (ja) 2011-11-30
US6514524B1 (en) 2003-02-04
PL342162A1 (en) 2001-05-21
CA2321267A1 (fr) 1999-08-26
AU3140899A (en) 1999-09-06
SI1410791T1 (sl) 2009-02-28
SI1056445T1 (en) 2004-10-31
SK12552000A3 (sk) 2001-02-12
HU226732B1 (en) 2009-08-28
ATE268164T1 (de) 2004-06-15
NO20004190L (no) 2000-10-20
EP1410791B1 (fr) 2008-09-17
DE69939605D1 (de) 2008-10-30
ID26022A (id) 2000-11-16
CA2321267C (fr) 2007-04-17
NO20004190D0 (no) 2000-08-22
EP1056445B1 (fr) 2004-06-02
ES2222695T3 (es) 2005-02-01
AU750785B2 (en) 2002-07-25
HUP0100970A3 (en) 2001-12-28
DK1056445T3 (da) 2004-10-04
KR20010034537A (ko) 2001-04-25
SK286248B6 (sk) 2008-06-06
EP1410791A1 (fr) 2004-04-21
CN1291091A (zh) 2001-04-11
FR2775188A1 (fr) 1999-08-27
RU2228201C2 (ru) 2004-05-10
AR018109A1 (es) 2001-10-31
OA11454A (en) 2003-12-08
HUP0100970A2 (hu) 2001-08-28
ES2314302T3 (es) 2009-03-16
SK285188B6 (sk) 2006-08-03
CN1182837C (zh) 2005-01-05
EP1056445A1 (fr) 2000-12-06
WO1999042086A9 (fr) 2000-08-31
DE69917750T2 (de) 2005-05-25
CZ20002940A3 (cs) 2000-11-15
KR100587181B1 (ko) 2006-06-08
PL191415B1 (pl) 2006-05-31
AP2000001943A0 (en) 2000-12-31
PT1056445E (pt) 2004-10-29
CZ299366B6 (cs) 2008-07-02
JP2002503686A (ja) 2002-02-05
WO1999042086A1 (fr) 1999-08-26
ATE408399T1 (de) 2008-10-15
DK1410791T3 (da) 2009-01-12

Similar Documents

Publication Publication Date Title
FR2775188B1 (fr) Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption
ATE304359T1 (de) Anti-östrogen- und progestin-enthaltende orale kontrazeptiva
MA26576A1 (fr) Formulation pharmaceutique orale a liberation prolongee
FR2786402B1 (fr) Dispositif de maintien d'un catheter sur la peau
MA26507A1 (fr) Compositions pharmaceutiques d'aerosol
EP1239359A4 (fr) Dissipateur thermique pour une unite centrale d'un ordinateur portable
BR9701304A (pt) Formulação de liberação prolongada
FR2798646B1 (fr) Dispositif de conditionnement et d'application
FR2727484B1 (fr) Structure d'attache pour gaine en forme de soufflet
FI953915A (fi) Dupuytrenin taudin lievittämiseen
NO20002126D0 (no) Formulering med forlenget frigjøring
FR2715729B1 (fr) Dispositif d'indication de couple.
IT1304008B1 (it) Dispositivo per l'eliminazione di ratti e simili.
DE69815270D1 (de) Dispositif pour remplacer la plaque d'impression
ITMI962423A0 (it) Composizione farmaceutica orale ad attivita' antipiretica analgesica e infiammatoria
EP0917001A4 (fr) Compositions de resine negative et leur application
FR2781118B1 (fr) Equipement d'ensileuse
IT1319105B1 (it) Procedimento per fabbricare opuscoli e dispositivo per l'esecuzionedel procedimento
FR2792690B1 (fr) Dispositif d'absorption de variation de couple
FR2797232B1 (fr) Dispositif d'actionnement
NO992737D0 (no) Formslippmiddel
ITRM940302A0 (it) "fermapalle ad assorbimento".
DZ2597A1 (fr) Dérivés d'urée.
FR2781851B1 (fr) Dispositif d'entrainement par pignons mene et menant
NO994305L (no) Anvendelse av 7<alfa>-metyl-17<alfa>-etinyl-estranderivater for behandling av aterosklerose

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 18

ST Notification of lapse

Effective date: 20161028