[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

HK1035142A1 - Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent. - Google Patents

Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent.

Info

Publication number
HK1035142A1
HK1035142A1 HK01105794A HK01105794A HK1035142A1 HK 1035142 A1 HK1035142 A1 HK 1035142A1 HK 01105794 A HK01105794 A HK 01105794A HK 01105794 A HK01105794 A HK 01105794A HK 1035142 A1 HK1035142 A1 HK 1035142A1
Authority
HK
Hong Kong
Prior art keywords
absorption
release
promoting agent
prolonged
orally administrable
Prior art date
Application number
HK01105794A
Other languages
English (en)
Inventor
Olivier Saslawski
Philippe Giet
Dominique Michel
Thierry Hulot
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HK1035142A1 publication Critical patent/HK1035142A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Addiction (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK01105794A 1998-02-23 2001-08-17 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent. HK1035142A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9802143A FR2775188B1 (fr) 1998-02-23 1998-02-23 Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption
PCT/EP1999/000994 WO1999042086A1 (fr) 1998-02-23 1999-02-16 Forme galenique s'administrant par voie orale, a liberation immediate et prolongee, et comprenant un agent favorisant l'absorption et utilisation de cet agent

Publications (1)

Publication Number Publication Date
HK1035142A1 true HK1035142A1 (en) 2001-11-16

Family

ID=9523244

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01105794A HK1035142A1 (en) 1998-02-23 2001-08-17 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent.

Country Status (28)

Country Link
US (2) US6426087B1 (fr)
EP (2) EP1410791B1 (fr)
JP (1) JP4828020B2 (fr)
KR (1) KR100587181B1 (fr)
CN (1) CN1182837C (fr)
AP (1) AP2000001943A0 (fr)
AR (2) AR018109A1 (fr)
AT (2) ATE268164T1 (fr)
AU (1) AU750785B2 (fr)
BR (1) BR9908121A (fr)
CA (1) CA2321267C (fr)
CZ (1) CZ299366B6 (fr)
DE (2) DE69917750T2 (fr)
DK (2) DK1410791T3 (fr)
ES (2) ES2222695T3 (fr)
FR (1) FR2775188B1 (fr)
HK (1) HK1035142A1 (fr)
HU (1) HU226732B1 (fr)
ID (1) ID26022A (fr)
NO (1) NO20004190L (fr)
OA (1) OA11454A (fr)
PL (2) PL191415B1 (fr)
PT (2) PT1056445E (fr)
RU (1) RU2228201C2 (fr)
SI (2) SI1410791T1 (fr)
SK (2) SK285188B6 (fr)
WO (1) WO1999042086A1 (fr)
ZA (1) ZA991408B (fr)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9925127D0 (en) * 1999-10-22 1999-12-22 Pharmacia & Upjohn Spa Oral formulations for anti-tumor compounds
FR2805462B1 (fr) * 2000-02-24 2003-08-15 Therabel Res Nouvelle forme galenique orale a liberation prolongee de la molsidomine
DE10026699A1 (de) 2000-05-30 2001-12-06 Basf Ag Formulierung auf Heparin-, Glycosaminoglycan- oder Heparinoidbasis und Verwendung der Formulierung sowie der Formulierungsgrundlage
US7183410B2 (en) * 2001-08-02 2007-02-27 Bidachem S.P.A. Stable polymorph of flibanserin
US20030060475A1 (en) * 2001-08-10 2003-03-27 Boehringer Ingelheim Pharma Kg Method of using flibanserin for neuroprotection
US10675280B2 (en) 2001-10-20 2020-06-09 Sprout Pharmaceuticals, Inc. Treating sexual desire disorders with flibanserin
UA78974C2 (en) * 2001-10-20 2007-05-10 Boehringer Ingelheim Pharma Use of flibanserin for treating disorders of sexual desire
SE0200475D0 (sv) * 2002-02-15 2002-02-15 Ltp Lipid Technologies Provide Oral farmaceutisk beredning
US7667053B2 (en) 2002-04-12 2010-02-23 Merck & Co., Inc. Bicyclic amides
US20040048877A1 (en) * 2002-05-22 2004-03-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions containing flibanserin
US10004729B2 (en) 2002-07-05 2018-06-26 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
US7771707B2 (en) 2004-06-12 2010-08-10 Collegium Pharmaceutical, Inc. Abuse-deterrent drug formulations
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
WO2004032860A2 (fr) 2002-10-07 2004-04-22 Chiron Corporation Formulations de vaccin anti-vih
US20040151769A1 (en) * 2002-12-31 2004-08-05 Boehringer Ingelheim International Gmbh Film coated tablet containing an extract of red vine leaves
ITRM20030074A1 (it) * 2003-02-21 2004-08-22 Pharmacia Italia Spa Formulazioni semisolide a rilascio immediato intese
US20040241252A1 (en) * 2003-05-29 2004-12-02 Abney Christopher Charles Pharmaceutical compositions for oral administration comprising lithium carbonate, processes of making the same, and methods of administering the same
WO2005060942A1 (fr) * 2003-12-19 2005-07-07 Aurobindo Pharma Ltd Composition pharmaceutique de metformine a liberation prolongee
MXPA06012059A (es) * 2004-04-22 2007-01-25 Boehringer Ingelheim Int Nuevas composiciones farmaceuticas para el tratamiento de los trastornos sexuales ii.
US20050239798A1 (en) * 2004-04-22 2005-10-27 Boehringer Ingelheim Pharmaceuticals, Inc. Method for the treatment of premenstrual and other female sexual disorders
US20080181946A1 (en) * 2004-05-14 2008-07-31 Braj Bhushan Lohray Controlled Release Delivery System For Metformin
US20060024370A1 (en) * 2004-07-29 2006-02-02 Cephalon France Modafinil oral lyophilizate
US20060025420A1 (en) * 2004-07-30 2006-02-02 Boehringer Ingelheimn International GmbH Pharmaceutical compositions for the treatment of female sexual disorders
WO2006024471A1 (fr) * 2004-09-03 2006-03-09 Boehringer Ingelheim International Gmbh Methode de traitement du trouble de l'hyperactivite avec deficit de l'attention
ATE500811T1 (de) * 2004-10-01 2011-03-15 Firmenich & Cie Parfümierende oder aromastoffabsondernde mikrokapseln mit einem explosionsunterdrücker
US20060199805A1 (en) * 2005-03-04 2006-09-07 Boehringer Ingelheim International Gmbh Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders
EP1858516A1 (fr) * 2005-03-04 2007-11-28 Boehringer Ingelheim International GmbH Compositions pharmaceutiques utiles dans le traitement et/ou la prevention de la depression
WO2006096439A2 (fr) * 2005-03-04 2006-09-14 Boehringer Ingelheim International Gmbh Compositions pharmaceutiques destinees au traitement et/ou a la prevention de la schizophrenie et de maladies associees
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
CA2608249A1 (fr) * 2005-05-06 2006-11-16 Boehringer Ingelheim International Gmbh Methode de traitement de la toxicomanie
US20060264511A1 (en) * 2005-05-19 2006-11-23 Boehringer Ingelheim International Gmbh Method for the treatment of drug-induced sexual dysfunction
WO2006125041A1 (fr) * 2005-05-19 2006-11-23 Boehringer Ingelheim International Gmbh Procede pour le traitement de dysfonctionnements sexuels dus a des etats pathologiques
ES2322777T3 (es) * 2005-06-21 2009-06-26 Merck Patent Gmbh Preparacion farmaceutica solida que contienen (r)-(-)-2-(5-(4-fluorfenil)-3-piridilmetilaminometil)-cromano.
EP1745788A1 (fr) * 2005-07-22 2007-01-24 KTB Tumorforschungsgesellschaft mbH Acylglycerophospholipides pour le traitement du cancer et de la cachexie
CA2617546C (fr) 2005-08-03 2014-07-15 Boehringer Ingelheim International Gmbh Utilisation de la flibanserine dans le traitement de l'obesite
US20070123540A1 (en) * 2005-10-29 2007-05-31 Angelo Ceci Sexual desire enhancing medicaments comprising benzimidazolone derivatives
JP2009513604A (ja) * 2005-10-29 2009-04-02 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 月経前障害及び他の女性の性的障害治療用のベンゾイミダゾロン誘導体
US20070105869A1 (en) * 2005-11-08 2007-05-10 Stephane Pollentier Use of flibanserin for the treatment of pre-menopausal sexual desire disorders
WO2007106957A1 (fr) * 2006-03-21 2007-09-27 Laboratoires Smb S.A. Formes galéniques flottantes multiples à libération contrôlée
HUE026156T2 (en) * 2006-05-09 2016-06-28 Sprout Pharmaceuticals Inc The use of Flibanserin for the treatment of sexual desire after menopause
WO2008000760A1 (fr) 2006-06-30 2008-01-03 Boehringer Ingelheim International Gmbh Flibansérine dans le traitement de l'incontinence urinaire et des maladies associées
EP2043648A1 (fr) * 2006-07-14 2009-04-08 Boehringer Ingelheim International GmbH Utilisation de flibansérine pour le traitement de troubles sexuels chez les femmes
MX2009001551A (es) * 2006-08-14 2009-02-20 Boehringer Ingelheim Int Formulaciones de flibanserina y metodo para fabricarlas.
CL2007002214A1 (es) * 2006-08-14 2008-03-07 Boehringer Ingelheim Int Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp
EA200900270A1 (ru) * 2006-08-25 2009-08-28 Бёрингер Ингельхайм Интернациональ Гмбх Системы регулируемого высвобождения и способ их приготовления
US20080081142A1 (en) * 2006-10-03 2008-04-03 Zeik Douglas B Articles and methods for applying color on surfaces
EP1952803A1 (fr) 2007-01-23 2008-08-06 KTB-Tumorforschungs GmbH Composition pharmaceutique solide contenant des phospholipides hydrogénés
WO2009033061A1 (fr) * 2007-09-07 2009-03-12 Xenoport, Inc. Promédicaments d'acamprosate à libération par cyclisation sous forme de néopentyl-sulfonylesters carboxylates masqués, compositions les comprenant et méthodes d'utilisation correspondantes
WO2009033079A1 (fr) * 2007-09-07 2009-03-12 Xenoport, Inc. Promédicaments de libération de cyclisation d'ester de néopentyle sulfonyle d'ester d'acide pantoïque masqués extérieurement, leurs compositions et procédés d'utilisation
CL2008002693A1 (es) 2007-09-12 2009-10-16 Boehringer Ingelheim Int Uso de flibanserina para el tratamiento de sintomas vasomotores seleccionados de sofocos, sudores nocturnos, cambios de estado de animo e irritabilidad
EP2042165A1 (fr) * 2007-09-28 2009-04-01 Swiss Caps Rechte und Lizenzen AG Capsules molles remplies avec un excipient thermofusible
WO2009052191A1 (fr) * 2007-10-15 2009-04-23 Xenoport, Inc. Promédicaments de l'acamprosate à libération par cyclisation de néopentylsulfonylester à masquage interne, leurs compositions et procédés d'utilisation
CA2638240C (fr) * 2008-08-29 2010-02-02 Alexander Macgregor Methode de traitement des anomalies de la glycemie et des variations de la glycemie
CA2750421C (fr) 2008-11-27 2016-10-18 B.R.A.I.N. Biotechnology Research And Information Network Ag Proteines tensioactives en tant qu'excipients dans des formulations pharmaceutiques solides
US10668060B2 (en) 2009-12-10 2020-06-02 Collegium Pharmaceutical, Inc. Tamper-resistant pharmaceutical compositions of opioids and other drugs
JP5714600B2 (ja) 2009-12-18 2015-05-07 フリースランドカンピナ・ネーデルランド・ホールディング・ビー.ブイ.FrieslandCampina Nederland Holding B.V. 共加工された錠用賦形剤混合物、その調製及び使用
JP5546900B2 (ja) * 2010-02-25 2014-07-09 ライオン株式会社 パナキサトリオール安定化組成物
EP2621487B1 (fr) * 2010-09-28 2017-05-03 Depomed, Inc. Formes pharmaceutiques à rétention gastrique pour la libération prolongée d'acamprosate dans le tractus gastro-intestinal supérieur
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
WO2013082573A1 (fr) * 2011-12-02 2013-06-06 Synchroneuron Inc. Formulations d'acamprosate, procédés d'utilisation de celles-ci, et combinaisons comprenant celles-ci
EP3578266B1 (fr) * 2013-03-15 2024-06-19 Sun Pharmaceutical Industries Limited Formulation d'acétate d'abiratérone
US20150246060A1 (en) 2013-03-15 2015-09-03 Iceutica Inc. Abiraterone Acetate Formulation and Methods of Use
EP3878445A3 (fr) 2013-06-05 2021-10-27 Synchroneuron Inc. Formulations d'acamprosate, leurs procédés d'utilisation et combinaisons les comprenant
US20150157646A1 (en) 2013-09-27 2015-06-11 Iceutica Inc. Abiraterone Steroid Formulation
WO2017222575A1 (fr) 2016-06-23 2017-12-28 Collegium Pharmaceutical, Inc. Procédé de préparation de formulations orales dissuasives d'abus plus stables
CA3062834A1 (fr) * 2017-05-17 2018-11-22 Confluence Pharmaceuticals, Llc Formulations d'homotaurines et de leurs sels
WO2023025672A1 (fr) 2021-08-25 2023-03-02 Basf Se Composition auxiliaire de compression directe

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI63335B (fi) * 1979-02-02 1983-02-28 Orion Yhtymae Oy Foerfarande foer framstaellning av tabletter med foerdroejd loslighet av effektaemne
FR2457281A1 (fr) * 1979-05-23 1980-12-19 Meram Lab Nouveaux derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee
GB8524421D0 (en) * 1985-10-03 1985-11-06 Boots Co Plc Therapeutic agents
JPS62265226A (ja) * 1986-05-12 1987-11-18 Fujisawa Pharmaceut Co Ltd 経口投与用製剤
ZA898331B (en) * 1988-11-22 1990-07-25 Hoffmann La Roche Pharmaceutical compositions
US5190748A (en) * 1988-11-22 1993-03-02 Hoffmann-La Roche Inc. Absorption enhancement of antibiotics
US5139786A (en) * 1989-07-07 1992-08-18 Ciba-Geigy Corporation Topical formulations
JPH03275633A (ja) * 1990-03-23 1991-12-06 Teikoku Seiyaku Co Ltd 生理活性ポリペプチドの吸収促進剤
US5138786A (en) 1991-07-17 1992-08-18 Fischer Michael G Insta-guard firearm protection
IT1255895B (it) * 1992-10-20 1995-11-17 Laura Chiodini Composizioni farmaceutiche contenenti una calcitonina
DE4432757A1 (de) * 1994-09-14 1996-03-21 Boehringer Mannheim Gmbh Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung
US5858398A (en) * 1994-11-03 1999-01-12 Isomed Inc. Microparticular pharmaceutical compositions
GB9516268D0 (en) * 1995-08-08 1995-10-11 Danbiosyst Uk Compositiion for enhanced uptake of polar drugs from the colon

Also Published As

Publication number Publication date
CA2321267A1 (fr) 1999-08-26
DK1056445T3 (da) 2004-10-04
ES2222695T3 (es) 2005-02-01
SK12552000A3 (sk) 2001-02-12
JP4828020B2 (ja) 2011-11-30
AR066843A2 (es) 2009-09-16
CZ20002940A3 (cs) 2000-11-15
KR100587181B1 (ko) 2006-06-08
DE69939605D1 (de) 2008-10-30
ID26022A (id) 2000-11-16
KR20010034537A (ko) 2001-04-25
SK286248B6 (sk) 2008-06-06
CN1182837C (zh) 2005-01-05
BR9908121A (pt) 2000-10-24
US6426087B1 (en) 2002-07-30
ES2314302T3 (es) 2009-03-16
FR2775188B1 (fr) 2001-03-09
DE69917750D1 (de) 2004-07-08
SI1056445T1 (en) 2004-10-31
EP1410791A1 (fr) 2004-04-21
EP1410791B1 (fr) 2008-09-17
US6514524B1 (en) 2003-02-04
NO20004190D0 (no) 2000-08-22
HUP0100970A3 (en) 2001-12-28
PL191415B1 (pl) 2006-05-31
NO20004190L (no) 2000-10-20
WO1999042086A1 (fr) 1999-08-26
EP1056445B1 (fr) 2004-06-02
AU3140899A (en) 1999-09-06
PL201851B1 (pl) 2009-05-29
SK285188B6 (sk) 2006-08-03
PT1056445E (pt) 2004-10-29
DK1410791T3 (da) 2009-01-12
DE69917750T2 (de) 2005-05-25
ZA991408B (en) 1999-08-23
EP1056445A1 (fr) 2000-12-06
AU750785B2 (en) 2002-07-25
JP2002503686A (ja) 2002-02-05
AR018109A1 (es) 2001-10-31
ATE268164T1 (de) 2004-06-15
AP2000001943A0 (en) 2000-12-31
PT1410791E (pt) 2008-12-24
HU226732B1 (en) 2009-08-28
RU2228201C2 (ru) 2004-05-10
HUP0100970A2 (hu) 2001-08-28
ATE408399T1 (de) 2008-10-15
WO1999042086A9 (fr) 2000-08-31
PL342162A1 (en) 2001-05-21
CN1291091A (zh) 2001-04-11
CA2321267C (fr) 2007-04-17
CZ299366B6 (cs) 2008-07-02
SI1410791T1 (sl) 2009-02-28
FR2775188A1 (fr) 1999-08-27
OA11454A (en) 2003-12-08

Similar Documents

Publication Publication Date Title
ZA991408B (en) Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent.
EG23821A (en) Oral pharmaceutical dosage forms comprising a protom pump inhibitor and an antacid agent or alginate
BR9912979B1 (pt) composição farmacêutica administrável oralmente, tablete de mascar, cápsula e uso de chitosan.
IL137445A0 (en) Pharmaceutically active compounds and methods of use thereof
PL351526A1 (en) Pharmaceutical formulation comprising amoxycillin
AP9901623A0 (en) Pharmaceutical formulations comprising amoxocyllin and clavulanate
ZA993200B (en) Use of nanodispersions in pharmaceutical end formulations.
EP1240136A4 (fr) Utilisation de composes de vitamine d biologiquement actifs pour prevenir et traiter la maladie intestinale inflammatoire
MXPA02004770A (es) Composiciones terapeuticas y metodos para su uso.
AU2002245629A1 (en) Stabilized therapeutic and imaging agents
HK1019205A1 (en) Galenic preparation for prevention and treatment of hepatocarcinoma.
MXPA02003174A (es) Combinacion novedosa de loteprednol y antihistaminicos.
HK1045804A1 (en) Improved pharmaceutical formulations comprising ritonavir
HK1040920A1 (en) Sustained release pharmaceutical composition and method of releasing pharmaceutically active agent.
NZ513650A (en) Pharmaceutical composition for the treatment of urinary incontinence, motion sickness and vertigo
HK1018211A1 (en) Pharmaceutical combination preparation of an inhibitor of the sodium/dydrogen exchanger and a medicament for the treatment of cardiovascular diseases.
HUP0001526A3 (en) Use of nucleozides for producing pharmaceutical compositions for cytokine related treatments of disease and the pharmaceutical compositions
NO20001717D0 (no) Serotonin-inneholdende formulering for oral administrering og anvendelse av samme
HUP0000910A3 (en) Aqueous pharmaceutical composition comprising an active ingredient which is highly insoluble in water
EP1308509A4 (fr) Peptide acitf sur le plan physiologique et utilisation de celui-ci
HU0800735D0 (hu) Orálisan adagolható, azonnali és nyújtott hatóanyag-felszabadítású, felszívódást elõsegítõ szert tartalmazó galenusi készítmény és ezen felszívódást elõsegítõ szer alkalmazása
ZA977957B (en) Pharmacologically active compounds and use.
ZA982851B (en) Pharmaceutical formulation comprising Tyrosine and DMPL.
HUP0301119A3 (en) Biologically active agent and drug
EP1154783A4 (fr) Medicaments comprenant de la relaxine et leur utilisation

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160216