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FR2457281A1 - Nouveaux derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee - Google Patents

Nouveaux derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee

Info

Publication number
FR2457281A1
FR2457281A1 FR7913207A FR7913207A FR2457281A1 FR 2457281 A1 FR2457281 A1 FR 2457281A1 FR 7913207 A FR7913207 A FR 7913207A FR 7913207 A FR7913207 A FR 7913207A FR 2457281 A1 FR2457281 A1 FR 2457281A1
Authority
FR
France
Prior art keywords
novel
acid derivatives
membrane activity
enhanced membrane
aminopropanesulfonic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7913207A
Other languages
English (en)
Other versions
FR2457281B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MERAM LAB
Original Assignee
MERAM LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MERAM LAB filed Critical MERAM LAB
Priority to FR7913207A priority Critical patent/FR2457281A1/fr
Priority to US06/150,946 priority patent/US4355043A/en
Priority to GR62000A priority patent/GR68547B/el
Priority to DE19803019350 priority patent/DE3019350A1/de
Priority to DE1996175017 priority patent/DE19675017I2/de
Priority to ZA00803051A priority patent/ZA803051B/xx
Priority to MA19051A priority patent/MA18855A1/fr
Priority to AT0274580A priority patent/AT372371B/de
Priority to CH3998/80A priority patent/CH647757A5/fr
Priority to IT67807/80A priority patent/IT1130455B/it
Priority to GB8016956A priority patent/GB2051789B/en
Priority to OA57119A priority patent/OA06606A/fr
Priority to BE0/200755A priority patent/BE883468A/fr
Priority to ES491787A priority patent/ES8101042A1/es
Priority to CA000352613A priority patent/CA1152100A/fr
Priority to AU58697/80A priority patent/AU535785B2/en
Priority to NL8002997A priority patent/NL191789C/xx
Priority to JP6796380A priority patent/JPS5625146A/ja
Publication of FR2457281A1 publication Critical patent/FR2457281A1/fr
Application granted granted Critical
Publication of FR2457281B1 publication Critical patent/FR2457281B1/fr
Priority to JP2276598A priority patent/JPH03148219A/ja
Priority to MX9203363A priority patent/MX9203363A/es
Priority to NL970003C priority patent/NL970003I2/nl
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • C07C309/15—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton the nitrogen atom of at least one of the amino groups being part of any of the groups, X being a hetero atom, Y being any atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'INVENTION CONCERNE LES NOUVEAUX SELS DE SODIUM, POTASSIUM, LITHIUM, CALCIUM, MAGNESIUM, ZINC DE LA N-ACETYLHOMOTAURINE PRESENTANT UNE ACTIVITE MEMBRANAIRE RENFORCEE, LEUR PROCEDE DE PREPARATION ET LEUR APPLICATION COMME MEDICAMENTS, NOTAMMENT NEUROTROPE, VASCULOTROPE ET ANTI-ASTHENIQUE.
FR7913207A 1979-05-23 1979-05-23 Nouveaux derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee Granted FR2457281A1 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR7913207A FR2457281A1 (fr) 1979-05-23 1979-05-23 Nouveaux derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee
US06/150,946 US4355043A (en) 1979-05-23 1980-05-19 Novel derivatives of 3-aminopropanesulfonic acid having a reinforced activity on membrane
GR62000A GR68547B (fr) 1979-05-23 1980-05-20
DE1996175017 DE19675017I2 (de) 1979-05-23 1980-05-21 Neue Derivate der 3-Aminopropansulfonsaeure diese enthaltende Arzneimittel sowie Verfahren zu ihrer Herstellung
DE19803019350 DE3019350A1 (de) 1979-05-23 1980-05-21 Neue derivate der 3-aminopropansulfonsaeure mit verstaerkten membranstabilisierenden eigenschaften
MA19051A MA18855A1 (fr) 1979-05-23 1980-05-22 Nouveaux derives de l'acide 3-aminopropane sulfonique ayant une activite membranaire renforcee
AT0274580A AT372371B (de) 1979-05-23 1980-05-22 Verfahren zur herstellung von neuen salzen der 3-acetylaminopropansulfonsaeure
CH3998/80A CH647757A5 (fr) 1979-05-23 1980-05-22 Derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee.
IT67807/80A IT1130455B (it) 1979-05-23 1980-05-22 Derivati dell acido & amminopropan solfonico ad attivita membranaria rinforzata e procedimento per la loro preparazione
GB8016956A GB2051789B (en) 1979-05-23 1980-05-22 Pharmacologically active 3-aminopropane solphonic acid derivatives
ZA00803051A ZA803051B (en) 1979-05-23 1980-05-22 Novel derivatives of 3-aminopropanesulfonic acid having a reinforced activity on membrane
CA000352613A CA1152100A (fr) 1979-05-23 1980-05-23 Derives d'acide 3-aminopropanesulfonique possedant une activite renforcee sur membrane
ES491787A ES8101042A1 (es) 1979-05-23 1980-05-23 Proceso de fabricacion de derivados del acido 3-aminopropa- nosulfonico
OA57119A OA06606A (fr) 1979-05-23 1980-05-23 Nouveaux dérivés de l'acide 3-aminopropanesulfonique ayant une activité membranaire renforcée.
AU58697/80A AU535785B2 (en) 1979-05-23 1980-05-23 3-aminopropane sulphonic acids
NL8002997A NL191789C (nl) 1979-05-23 1980-05-23 Acetylaminoalkaansulfonzuurderivaten met farmacologische eigenschappen.
JP6796380A JPS5625146A (en) 1979-05-23 1980-05-23 33aminopropanesulfonic acid derivative
BE0/200755A BE883468A (fr) 1979-05-23 1980-05-23 Nouveaux derives de l'acide 3-amino-propane-sulfonique ayant une activite membranaire renforcee.
JP2276598A JPH03148219A (ja) 1979-05-23 1990-10-17 膜安定化剤
MX9203363A MX9203363A (es) 1979-05-23 1992-06-25 Nuevos derivados de acido 3-aminopropansulfonico y composiciones farmaceuticas que los contienen.
NL970003C NL970003I2 (nl) 1979-05-23 1997-01-22 Acetylaminoalkaansulfonzuurderivaten met farmacologische eigenschappen.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7913207A FR2457281A1 (fr) 1979-05-23 1979-05-23 Nouveaux derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee

Publications (2)

Publication Number Publication Date
FR2457281A1 true FR2457281A1 (fr) 1980-12-19
FR2457281B1 FR2457281B1 (fr) 1983-10-07

Family

ID=9225819

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7913207A Granted FR2457281A1 (fr) 1979-05-23 1979-05-23 Nouveaux derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee

Country Status (18)

Country Link
US (1) US4355043A (fr)
JP (2) JPS5625146A (fr)
AT (1) AT372371B (fr)
AU (1) AU535785B2 (fr)
BE (1) BE883468A (fr)
CA (1) CA1152100A (fr)
CH (1) CH647757A5 (fr)
DE (2) DE19675017I2 (fr)
ES (1) ES8101042A1 (fr)
FR (1) FR2457281A1 (fr)
GB (1) GB2051789B (fr)
GR (1) GR68547B (fr)
IT (1) IT1130455B (fr)
MA (1) MA18855A1 (fr)
MX (1) MX9203363A (fr)
NL (2) NL191789C (fr)
OA (1) OA06606A (fr)
ZA (1) ZA803051B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999037606A1 (fr) * 1998-01-27 1999-07-29 Lipha Nouveaux derives d'acides aminoalkane sulfoniques, phosphoniques et phosphiniques, leur preparation et leur utilisation comme medicaments
WO1999042086A1 (fr) * 1998-02-23 1999-08-26 Merck Patent Gmbh Forme galenique s'administrant par voie orale, a liberation immediate et prolongee, et comprenant un agent favorisant l'absorption et utilisation de cet agent

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU193197B (en) * 1984-02-03 1987-08-28 Egyt Gyogyszervegyeszeti Gyar Preparatives regulating the growth of plants containing as reagent derivatives of n-substituated amin-prophansulphonic acid and process for production of the reagent
JPH0725771B2 (ja) * 1992-06-18 1995-03-22 財団法人生産開発科学研究所 ２−アミノエタンスルホン酸亜鉛錯化合物
US20040208875A1 (en) * 1995-03-15 2004-10-21 Queen's University At Kingston Method for treating amyloidosis
AU703540B2 (en) * 1996-03-26 1999-03-25 Meddiss, Incorporated Methods for inducing analgesia or anesthesia and treating or preventing ischemic injury of tissues in general
US6057373A (en) * 1997-05-22 2000-05-02 Synchroneuron, Llc Methods of treating tardive dyskinesia and other movement disorders using NMDA receptor antagonists
AU765522B2 (en) * 1998-01-13 2003-09-18 Synchroneuron, Llc Methods of treating tardive dyskinesia and other movement disorders
US5952389A (en) * 1998-01-13 1999-09-14 Synchroneuron Methods of treating tardive dyskinesia and other movement disorders
US6294583B1 (en) * 1998-01-13 2001-09-25 Synchroneuron, Llc Methods of treating tardive dyskinesia and other movement disorders
US6391922B1 (en) 1998-01-13 2002-05-21 Synchroneuron, Llc Treatment of posttraumatic stress disorder, obsessive-compulsive disorder and related neuropsychiatric disorders
US20020022657A1 (en) * 1998-02-11 2002-02-21 Francine Gervais Methods for modulating neuronal cell death
JP4726304B2 (ja) * 1999-04-28 2011-07-20 ベルス ヘルス （インターナショナル） リミティッド アミロイドーシスを治療するための組成物および方法
US6562836B1 (en) * 1999-05-24 2003-05-13 Queen's University Of Kingston Methods and compounds for inhibiting amyloid deposits
US7414076B2 (en) * 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US20070010573A1 (en) * 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7244764B2 (en) * 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US20060183800A1 (en) * 2004-11-12 2006-08-17 Xianqi Kong Methods and fluorinated compositions for treating amyloid-related diseases
JP2008520647A (ja) * 2004-11-16 2008-06-19 ニューロケム （インターナショナル） リミテッド Ｃｎｓおよびアミロイド関連疾患治療のための化合物
AU2005326962A1 (en) * 2004-12-22 2006-08-17 Bellus Health (International) Limited Methods and compositions for treating amyloid-related diseases
TW200716088A (en) * 2005-04-15 2007-05-01 Neurochem Int Ltd Formulations and methods for treating amyloidosis
ATE481094T1 (de) * 2005-12-22 2010-10-15 Kiacta Sarl Behandlung von diabetischer nephropathie
BRPI0717794B8 (pt) 2006-10-12 2021-05-25 Bellus Health International Ltd composto e composição farmacêutica de ácido 3-amino-1-propanosulfônico
MX2009006768A (es) * 2006-12-22 2009-08-31 Bellus Health Int Ltd Metodos, compuestos, y composiciones para tratar trastornos metabolicos y diabetes.
KR100877134B1 (ko) * 2007-05-03 2009-01-09 주식회사 엔지켐 아캄프로세이트 칼슘의 제조방법
EP2217564A1 (fr) * 2007-09-07 2010-08-18 XenoPort, Inc. Promédicaments de libération de cyclisation d'ester de néopentyle sulfonyle d'ester d'acide pantoïque complexe d'acamprosate, leurs compositions et procédés d'utilisation
WO2009033079A1 (fr) * 2007-09-07 2009-03-12 Xenoport, Inc. Promédicaments de libération de cyclisation d'ester de néopentyle sulfonyle d'ester d'acide pantoïque masqués extérieurement, leurs compositions et procédés d'utilisation
TW200932734A (en) * 2007-10-15 2009-08-01 Xenoport Inc Internally masked neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use
CN101492400B (zh) * 2008-01-22 2014-03-12 北京华禧联合科技发展有限公司 一种高纯度阿坎酸钙的制备方法
DE102008048791A1 (de) 2008-09-24 2010-03-25 Merck Patent Gmbh Neue Kristallform von Calcium-3-Acetylaminopropan-1-sulfonat
IT1392327B1 (it) * 2008-09-26 2012-02-28 Laboratorio Chimico Int Spa Nuova forma polimorfa del calcio acamprosato
CN104478766A (zh) * 2014-12-25 2015-04-01 北京华禧联合科技发展有限公司 一种制备高纯度乙酰基高牛磺酸的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2321285A1 (fr) * 1975-08-18 1977-03-18 Stanley Drug Products Inc Agents antifibrinolytiques
FR2384751A1 (fr) * 1977-03-23 1978-10-20 Francaise Coop Pharma Nouveaux derives de la taurine a activite neuro-musculaire renforcee

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3039916A (en) * 1961-03-27 1962-06-19 West Laboratories Inc Anionic iodine complexes
US3544597A (en) * 1969-06-12 1970-12-01 Rohm & Haas Process for manufacturing sulfonated amides
JPS5418714B2 (fr) * 1974-10-08 1979-07-10
US4233229A (en) * 1978-01-03 1980-11-11 Gaf Corporation Preparation of salt-free N-acyl taurines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2321285A1 (fr) * 1975-08-18 1977-03-18 Stanley Drug Products Inc Agents antifibrinolytiques
FR2384751A1 (fr) * 1977-03-23 1978-10-20 Francaise Coop Pharma Nouveaux derives de la taurine a activite neuro-musculaire renforcee

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999037606A1 (fr) * 1998-01-27 1999-07-29 Lipha Nouveaux derives d'acides aminoalkane sulfoniques, phosphoniques et phosphiniques, leur preparation et leur utilisation comme medicaments
US6265437B1 (en) * 1998-01-27 2001-07-24 Lipha Aminoalkanesulphonic acid derivatives, their preparation and their use as medicaments
WO1999042086A1 (fr) * 1998-02-23 1999-08-26 Merck Patent Gmbh Forme galenique s'administrant par voie orale, a liberation immediate et prolongee, et comprenant un agent favorisant l'absorption et utilisation de cet agent
FR2775188A1 (fr) * 1998-02-23 1999-08-27 Lipha Forme galenique a liberation immediate ou liberation prolongee administrable par voie orale comprenant un agent promoteur d'absorption et utilisation de cet agent promoteur d'absorption
US6426087B1 (en) 1998-02-23 2002-07-30 Merck Patent Gesellschaft Mit Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent
US6514524B1 (en) 1998-02-23 2003-02-04 Merck Patentgesellschaft Mit Orally administerable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent

Also Published As

Publication number Publication date
DE19675017I2 (de) 2001-04-26
NL8002997A (nl) 1980-11-25
DE3019350A1 (de) 1980-12-04
MX9203363A (es) 1992-07-01
OA06606A (fr) 1981-08-31
CH647757A5 (fr) 1985-02-15
AT372371B (de) 1983-09-26
MA18855A1 (fr) 1980-12-31
ES491787A0 (es) 1980-12-16
JPH0317825B2 (fr) 1991-03-11
JPH0524135B2 (fr) 1993-04-06
NL191789C (nl) 1996-08-02
CA1152100A (fr) 1983-08-16
IT8067807A0 (it) 1980-05-22
DE3019350C2 (fr) 1989-11-30
FR2457281B1 (fr) 1983-10-07
GB2051789B (en) 1983-04-27
IT1130455B (it) 1986-06-11
ZA803051B (en) 1981-06-24
AU5869780A (en) 1980-11-27
ES8101042A1 (es) 1980-12-16
JPS5625146A (en) 1981-03-10
NL970003I1 (nl) 1997-04-01
AU535785B2 (en) 1984-04-05
JPH03148219A (ja) 1991-06-25
ATA274580A (de) 1983-02-15
GB2051789A (en) 1981-01-21
US4355043A (en) 1982-10-19
NL970003I2 (nl) 1997-08-01
NL191789B (nl) 1996-04-01
BE883468A (fr) 1980-11-24
GR68547B (fr) 1982-01-18

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CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0353, 920529

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0353, 790523

CL Concession to grant licences
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TP Transmission of property