ATE260105T1 - Zubereitung enthaltend eine molekulardispersion mit erhöhter bioverfügbarkeit - Google Patents
Zubereitung enthaltend eine molekulardispersion mit erhöhter bioverfügbarkeitInfo
- Publication number
- ATE260105T1 ATE260105T1 AT98963031T AT98963031T ATE260105T1 AT E260105 T1 ATE260105 T1 AT E260105T1 AT 98963031 T AT98963031 T AT 98963031T AT 98963031 T AT98963031 T AT 98963031T AT E260105 T1 ATE260105 T1 AT E260105T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation containing
- increased bioavailability
- molecular dispersion
- dispersion
- molecular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99716897A | 1997-12-22 | 1997-12-22 | |
PCT/US1998/026218 WO1999032118A1 (en) | 1997-12-22 | 1998-12-17 | Molecular dispersion composition with enhanced bioavailability |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE260105T1 true ATE260105T1 (de) | 2004-03-15 |
Family
ID=25543717
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98963031T ATE260105T1 (de) | 1997-12-22 | 1998-12-17 | Zubereitung enthaltend eine molekulardispersion mit erhöhter bioverfügbarkeit |
Country Status (28)
Country | Link |
---|---|
EP (1) | EP1039908B1 (de) |
JP (2) | JP2001526227A (de) |
KR (1) | KR100597331B1 (de) |
CN (1) | CN1116039C (de) |
AR (1) | AR017436A1 (de) |
AT (1) | ATE260105T1 (de) |
AU (1) | AU761994C (de) |
BR (1) | BR9813728A (de) |
CA (1) | CA2315685C (de) |
CO (1) | CO4970793A1 (de) |
CZ (1) | CZ295956B6 (de) |
DE (1) | DE69821984T2 (de) |
DK (1) | DK1039908T3 (de) |
ES (1) | ES2214757T3 (de) |
HK (1) | HK1027040A1 (de) |
HU (1) | HU229052B1 (de) |
ID (1) | ID28304A (de) |
IL (1) | IL136460A0 (de) |
MY (1) | MY126580A (de) |
NO (1) | NO327383B1 (de) |
NZ (1) | NZ504834A (de) |
PE (1) | PE20000012A1 (de) |
PL (1) | PL192423B1 (de) |
PT (1) | PT1039908E (de) |
SK (1) | SK285662B6 (de) |
TW (1) | TW527196B (de) |
WO (1) | WO1999032118A1 (de) |
ZA (1) | ZA9811592B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6524832B1 (en) | 1994-02-04 | 2003-02-25 | Arch Development Corporation | DNA damaging agents in combination with tyrosine kinase inhibitors |
US6632455B2 (en) | 1997-12-22 | 2003-10-14 | Schering Corporation | Molecular dispersion composition with enhanced bioavailability |
US6316462B1 (en) * | 1999-04-09 | 2001-11-13 | Schering Corporation | Methods of inducing cancer cell death and tumor regression |
ATE444060T1 (de) | 2001-06-22 | 2009-10-15 | Pfizer Prod Inc | Pharmazeutische zusammensetzungen enthaltend dispersionen aus arzneistoffen und neutralen polymeren |
WO2003075893A1 (en) * | 2002-03-04 | 2003-09-18 | Teva Pharmaceutical Industries Ltd. | Controlled release dosage forms |
SA07280459B1 (ar) | 2006-08-25 | 2011-07-20 | بيورديو فارما إل. بي. | أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني |
PT103661B (pt) | 2007-02-23 | 2010-09-07 | Hovione Farmaciencia S A | Processo de preparação de minociclina base cristalina |
WO2008136393A1 (ja) * | 2007-04-27 | 2008-11-13 | Ajinomoto Co., Inc. | ラクタム化合物の結晶形およびその製造方法 |
US8835635B2 (en) * | 2012-06-05 | 2014-09-16 | Symed Labs Limited | Amorphous form of vilazodone hydrochloride substantially free of crystalline forms |
WO2016198983A1 (en) | 2015-06-09 | 2016-12-15 | Bend Research Inc. | Formulations to achieve rapid dissolution of drug from spray-dried dispersions in capsules |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2546577B2 (de) * | 1975-10-17 | 1981-04-02 | Sandoz-Patent-GmbH, 7850 Lörrach | Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden |
EP0214092A1 (de) * | 1985-08-08 | 1987-03-11 | Ciba-Geigy Ag | Absorption von psychoaktiven 2-Aryl-pyrazoloquinolinen in Form einer festen Molekulardispersion in Polyvinylpyrrolidon |
ATE157864T1 (de) * | 1991-12-18 | 1997-09-15 | Warner Lambert Co | Verfahren für die herstellung einer festen dispersion |
JPH0848632A (ja) * | 1994-08-08 | 1996-02-20 | Kanebo Ltd | エトポシドを含有する固形組成物および固形製剤 |
DK1019392T3 (da) * | 1995-12-22 | 2006-03-20 | Schering Corp | Tricykliske amider anvendelige til inhibering af G-proteinfunktion og til behandling af proliferative sygdomme |
ATE273002T1 (de) * | 1996-06-28 | 2004-08-15 | Schering Corp | Feste lösung eines fungizids mit erhöhter bioverfügbarkeit |
-
1998
- 1998-12-17 AT AT98963031T patent/ATE260105T1/de active
- 1998-12-17 TW TW087121048A patent/TW527196B/zh not_active IP Right Cessation
- 1998-12-17 DE DE69821984T patent/DE69821984T2/de not_active Expired - Lifetime
- 1998-12-17 JP JP2000525109A patent/JP2001526227A/ja not_active Withdrawn
- 1998-12-17 NZ NZ504834A patent/NZ504834A/en not_active IP Right Cessation
- 1998-12-17 CO CO98075234A patent/CO4970793A1/es unknown
- 1998-12-17 CZ CZ20002304A patent/CZ295956B6/cs not_active IP Right Cessation
- 1998-12-17 MY MYPI98005697A patent/MY126580A/en unknown
- 1998-12-17 ZA ZA9811592A patent/ZA9811592B/xx unknown
- 1998-12-17 HU HU0100850A patent/HU229052B1/hu not_active IP Right Cessation
- 1998-12-17 ID IDW20001216A patent/ID28304A/id unknown
- 1998-12-17 ES ES98963031T patent/ES2214757T3/es not_active Expired - Lifetime
- 1998-12-17 PL PL341344A patent/PL192423B1/pl not_active IP Right Cessation
- 1998-12-17 IL IL13646098A patent/IL136460A0/xx not_active IP Right Cessation
- 1998-12-17 DK DK98963031T patent/DK1039908T3/da active
- 1998-12-17 PE PE1998001243A patent/PE20000012A1/es not_active Application Discontinuation
- 1998-12-17 CA CA002315685A patent/CA2315685C/en not_active Expired - Lifetime
- 1998-12-17 SK SK896-2000A patent/SK285662B6/sk not_active IP Right Cessation
- 1998-12-17 EP EP98963031A patent/EP1039908B1/de not_active Expired - Lifetime
- 1998-12-17 KR KR1020007006866A patent/KR100597331B1/ko not_active IP Right Cessation
- 1998-12-17 AU AU18143/99A patent/AU761994C/en not_active Expired
- 1998-12-17 PT PT98963031T patent/PT1039908E/pt unknown
- 1998-12-17 AR ARP980106455A patent/AR017436A1/es active IP Right Grant
- 1998-12-17 CN CN98812483A patent/CN1116039C/zh not_active Expired - Fee Related
- 1998-12-17 BR BR9813728-0A patent/BR9813728A/pt not_active Application Discontinuation
- 1998-12-17 WO PCT/US1998/026218 patent/WO1999032118A1/en active IP Right Grant
-
2000
- 2000-06-21 NO NO20003235A patent/NO327383B1/no not_active IP Right Cessation
- 2000-10-09 HK HK00106351A patent/HK1027040A1/xx not_active IP Right Cessation
-
2009
- 2009-12-16 JP JP2009285733A patent/JP2010059212A/ja not_active Withdrawn
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
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