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ATE157864T1 - Verfahren für die herstellung einer festen dispersion - Google Patents

Verfahren für die herstellung einer festen dispersion

Info

Publication number
ATE157864T1
ATE157864T1 AT92925333T AT92925333T ATE157864T1 AT E157864 T1 ATE157864 T1 AT E157864T1 AT 92925333 T AT92925333 T AT 92925333T AT 92925333 T AT92925333 T AT 92925333T AT E157864 T1 ATE157864 T1 AT E157864T1
Authority
AT
Austria
Prior art keywords
drug
producing
solid dispersion
polymer
carrier
Prior art date
Application number
AT92925333T
Other languages
English (en)
Inventor
Isaac Ghebre-Sellassie
Robert Reisch Jr
Riten Parikh
Mahdi B Fawzi
Russell U Nesbitt
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE157864T1 publication Critical patent/ATE157864T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Glanulating (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Ceramic Products (AREA)
AT92925333T 1991-12-18 1992-11-18 Verfahren für die herstellung einer festen dispersion ATE157864T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80965691A 1991-12-18 1991-12-18

Publications (1)

Publication Number Publication Date
ATE157864T1 true ATE157864T1 (de) 1997-09-15

Family

ID=25201894

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92925333T ATE157864T1 (de) 1991-12-18 1992-11-18 Verfahren für die herstellung einer festen dispersion

Country Status (17)

Country Link
US (3) US6677362B1 (de)
EP (1) EP0617612B1 (de)
JP (1) JP3722293B2 (de)
AT (1) ATE157864T1 (de)
AU (1) AU671811B2 (de)
CA (1) CA2124821C (de)
DE (1) DE69222182T2 (de)
DK (1) DK0617612T3 (de)
ES (1) ES2109377T3 (de)
GR (1) GR3025501T3 (de)
IL (1) IL104179A (de)
MX (1) MX9207390A (de)
NZ (1) NZ245483A (de)
PT (1) PT101132B (de)
SG (1) SG43179A1 (de)
WO (1) WO1993011749A1 (de)
ZA (1) ZA929789B (de)

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Also Published As

Publication number Publication date
JP3722293B2 (ja) 2005-11-30
MX9207390A (es) 1993-06-01
SG43179A1 (en) 1997-10-17
DE69222182D1 (de) 1997-10-16
EP0617612B1 (de) 1997-09-10
ZA929789B (en) 1993-06-23
AU3142693A (en) 1993-07-19
WO1993011749A1 (en) 1993-06-24
DK0617612T3 (da) 1998-04-14
AU671811B2 (en) 1996-09-12
PT101132B (pt) 2000-02-29
CA2124821A1 (en) 1993-06-24
DE69222182T2 (de) 1998-02-26
IL104179A (en) 1997-11-20
GR3025501T3 (en) 1998-02-27
EP0617612A1 (de) 1994-10-05
US20040110694A1 (en) 2004-06-10
JPH07504162A (ja) 1995-05-11
PT101132A (pt) 1994-03-31
ES2109377T3 (es) 1998-01-16
NZ245483A (en) 1995-12-21
CA2124821C (en) 2003-10-07
US20010044409A1 (en) 2001-11-22
IL104179A0 (en) 1993-05-13
US6677362B1 (en) 2004-01-13

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