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NO20003235L - Molekyldispersjonsmateriale med forbedret biotilgjengelighet - Google Patents

Molekyldispersjonsmateriale med forbedret biotilgjengelighet

Info

Publication number
NO20003235L
NO20003235L NO20003235A NO20003235A NO20003235L NO 20003235 L NO20003235 L NO 20003235L NO 20003235 A NO20003235 A NO 20003235A NO 20003235 A NO20003235 A NO 20003235A NO 20003235 L NO20003235 L NO 20003235L
Authority
NO
Norway
Prior art keywords
improved bioavailability
dispersion material
molecular dispersion
molecular
bioavailability
Prior art date
Application number
NO20003235A
Other languages
English (en)
Other versions
NO20003235D0 (no
NO327383B1 (no
Inventor
Surendra A Sangekar
Ping I Lee
Amin A Nomeir
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO20003235D0 publication Critical patent/NO20003235D0/no
Publication of NO20003235L publication Critical patent/NO20003235L/no
Publication of NO327383B1 publication Critical patent/NO327383B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20003235A 1997-12-22 2000-06-21 Farmasoytisk formulering omfattende molekyldispersjonsmateriale med forbedret biotilgjengelighet NO327383B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99716897A 1997-12-22 1997-12-22
PCT/US1998/026218 WO1999032118A1 (en) 1997-12-22 1998-12-17 Molecular dispersion composition with enhanced bioavailability

Publications (3)

Publication Number Publication Date
NO20003235D0 NO20003235D0 (no) 2000-06-21
NO20003235L true NO20003235L (no) 2000-07-27
NO327383B1 NO327383B1 (no) 2009-06-22

Family

ID=25543717

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003235A NO327383B1 (no) 1997-12-22 2000-06-21 Farmasoytisk formulering omfattende molekyldispersjonsmateriale med forbedret biotilgjengelighet

Country Status (28)

Country Link
EP (1) EP1039908B1 (no)
JP (2) JP2001526227A (no)
KR (1) KR100597331B1 (no)
CN (1) CN1116039C (no)
AR (1) AR017436A1 (no)
AT (1) ATE260105T1 (no)
AU (1) AU761994C (no)
BR (1) BR9813728A (no)
CA (1) CA2315685C (no)
CO (1) CO4970793A1 (no)
CZ (1) CZ295956B6 (no)
DE (1) DE69821984T2 (no)
DK (1) DK1039908T3 (no)
ES (1) ES2214757T3 (no)
HK (1) HK1027040A1 (no)
HU (1) HU229052B1 (no)
ID (1) ID28304A (no)
IL (1) IL136460A0 (no)
MY (1) MY126580A (no)
NO (1) NO327383B1 (no)
NZ (1) NZ504834A (no)
PE (1) PE20000012A1 (no)
PL (1) PL192423B1 (no)
PT (1) PT1039908E (no)
SK (1) SK285662B6 (no)
TW (1) TW527196B (no)
WO (1) WO1999032118A1 (no)
ZA (1) ZA9811592B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524832B1 (en) 1994-02-04 2003-02-25 Arch Development Corporation DNA damaging agents in combination with tyrosine kinase inhibitors
US6632455B2 (en) 1997-12-22 2003-10-14 Schering Corporation Molecular dispersion composition with enhanced bioavailability
US6316462B1 (en) * 1999-04-09 2001-11-13 Schering Corporation Methods of inducing cancer cell death and tumor regression
ATE444060T1 (de) 2001-06-22 2009-10-15 Pfizer Prod Inc Pharmazeutische zusammensetzungen enthaltend dispersionen aus arzneistoffen und neutralen polymeren
WO2003075893A1 (en) * 2002-03-04 2003-09-18 Teva Pharmaceutical Industries Ltd. Controlled release dosage forms
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
PT103661B (pt) 2007-02-23 2010-09-07 Hovione Farmaciencia S A Processo de preparação de minociclina base cristalina
WO2008136393A1 (ja) * 2007-04-27 2008-11-13 Ajinomoto Co., Inc. ラクタム化合物の結晶形およびその製造方法
US8835635B2 (en) * 2012-06-05 2014-09-16 Symed Labs Limited Amorphous form of vilazodone hydrochloride substantially free of crystalline forms
WO2016198983A1 (en) 2015-06-09 2016-12-15 Bend Research Inc. Formulations to achieve rapid dissolution of drug from spray-dried dispersions in capsules

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2546577B2 (de) * 1975-10-17 1981-04-02 Sandoz-Patent-GmbH, 7850 Lörrach Feste Stoffe aus Polyvinylpyrrolidon und Ergotalkaloiden
EP0214092A1 (en) * 1985-08-08 1987-03-11 Ciba-Geigy Ag Enhanced absorption of psychoactive 2-aryl-pyrazolo quinolines as a solid molecular dispersion in polyvinylpyrrolidone
ATE157864T1 (de) * 1991-12-18 1997-09-15 Warner Lambert Co Verfahren für die herstellung einer festen dispersion
JPH0848632A (ja) * 1994-08-08 1996-02-20 Kanebo Ltd エトポシドを含有する固形組成物および固形製剤
DK1019392T3 (da) * 1995-12-22 2006-03-20 Schering Corp Tricykliske amider anvendelige til inhibering af G-proteinfunktion og til behandling af proliferative sygdomme
ATE273002T1 (de) * 1996-06-28 2004-08-15 Schering Corp Feste lösung eines fungizids mit erhöhter bioverfügbarkeit

Also Published As

Publication number Publication date
CA2315685C (en) 2008-02-05
MY126580A (en) 2006-10-31
CZ20002304A3 (cs) 2001-04-11
SK8962000A3 (en) 2001-07-10
AU1814399A (en) 1999-07-12
HU229052B1 (en) 2013-07-29
PT1039908E (pt) 2004-06-30
ID28304A (id) 2001-05-10
DK1039908T3 (da) 2004-05-03
HK1027040A1 (en) 2001-01-05
KR20010033397A (ko) 2001-04-25
ES2214757T3 (es) 2004-09-16
JP2001526227A (ja) 2001-12-18
PL192423B1 (pl) 2006-10-31
AR017436A1 (es) 2001-09-05
EP1039908B1 (en) 2004-02-25
NZ504834A (en) 2001-12-21
HUP0100850A3 (en) 2002-12-28
BR9813728A (pt) 2000-10-10
ATE260105T1 (de) 2004-03-15
JP2010059212A (ja) 2010-03-18
DE69821984T2 (de) 2004-12-30
CN1116039C (zh) 2003-07-30
KR100597331B1 (ko) 2006-07-10
CA2315685A1 (en) 1999-07-01
ZA9811592B (en) 1999-06-17
DE69821984D1 (de) 2004-04-01
NO20003235D0 (no) 2000-06-21
WO1999032118A1 (en) 1999-07-01
EP1039908A1 (en) 2000-10-04
HUP0100850A2 (hu) 2001-10-28
CN1282245A (zh) 2001-01-31
NO327383B1 (no) 2009-06-22
SK285662B6 (sk) 2007-05-03
CO4970793A1 (es) 2000-11-07
IL136460A0 (en) 2001-06-14
PL341344A1 (en) 2001-04-09
AU761994C (en) 2004-01-08
AU761994B2 (en) 2003-06-12
PE20000012A1 (es) 2000-01-18
TW527196B (en) 2003-04-11
CZ295956B6 (cs) 2005-12-14

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Legal Events

Date Code Title Description
CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: MERCK SHARP AND DOHME CORP

Free format text: NEW ADDRESS: 126 EAST LINCOLN AVENUE, US-NJ07065 RAHWAY, US

MM1K Lapsed by not paying the annual fees