[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

MD1449F1 - Derivati ai 2-amino-1,2,3,4-tetrahidronaftalinei cu actiune asupra sistemului cardiovascular, procedeu de obtinere a acestora si compozitii farmaceutice care ii contin - Google Patents

Derivati ai 2-amino-1,2,3,4-tetrahidronaftalinei cu actiune asupra sistemului cardiovascular, procedeu de obtinere a acestora si compozitii farmaceutice care ii contin

Info

Publication number
MD1449F1
MD1449F1 MD96-0271A MD960271A MD1449F1 MD 1449 F1 MD1449 F1 MD 1449F1 MD 960271 A MD960271 A MD 960271A MD 1449 F1 MD1449 F1 MD 1449F1
Authority
MD
Moldova
Prior art keywords
amino
pharmaceutical compositions
preparation
compositions containing
cardiovascular system
Prior art date
Application number
MD96-0271A
Other languages
English (en)
Other versions
MD1449G2 (ro
MD960271A (ro
Inventor
Francesco Santangelo
Giorgio Bertolini
Cesare Casagrande
Francesco Marchini
Stefania Montanari
Claudio Semeraro
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of MD960271A publication Critical patent/MD960271A/ro
Publication of MD1449F1 publication Critical patent/MD1449F1/ro
Publication of MD1449G2 publication Critical patent/MD1449G2/ro

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/26Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/40Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
    • C07C271/42Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/44Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MD96-0271A 1992-03-17 1993-03-13 Derivaţi ai 2-amino-1,2,3,4-tetrahidronaftalinei cu acţiune asupra sistemului cardiovascular, procedeu de obţinere a acestora şi compoziţii farmaceutice care îi conţin MD1449G2 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI920608A IT1254521B (it) 1992-03-17 1992-03-17 Derivati della 2-ammino-tetralina attivi sul sistema cardiovascolare
PCT/EP1993/000577 WO1993019036A1 (en) 1992-03-17 1993-03-13 2-amino-1,2,3,4-tetrahydronaphthalene derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
MD960271A MD960271A (ro) 1997-09-30
MD1449F1 true MD1449F1 (ro) 2000-04-30
MD1449G2 MD1449G2 (ro) 2000-12-31

Family

ID=11362451

Family Applications (1)

Application Number Title Priority Date Filing Date
MD96-0271A MD1449G2 (ro) 1992-03-17 1993-03-13 Derivaţi ai 2-amino-1,2,3,4-tetrahidronaftalinei cu acţiune asupra sistemului cardiovascular, procedeu de obţinere a acestora şi compoziţii farmaceutice care îi conţin

Country Status (20)

Country Link
US (2) US5407956A (ro)
EP (1) EP0585440B1 (ro)
JP (1) JP3231775B2 (ro)
KR (1) KR100283945B1 (ro)
AT (1) ATE137737T1 (ro)
CA (1) CA2102490C (ro)
DE (1) DE69302544T2 (ro)
DK (1) DK0585440T3 (ro)
ES (1) ES2087729T3 (ro)
FI (1) FI935066A (ro)
GR (1) GR3020419T3 (ro)
HU (2) HUT68936A (ro)
IT (1) IT1254521B (ro)
MD (1) MD1449G2 (ro)
NO (1) NO180230C (ro)
NZ (1) NZ249845A (ro)
OA (1) OA09843A (ro)
PL (2) PL172056B1 (ro)
RU (1) RU2120435C1 (ro)
WO (1) WO1993019036A1 (ro)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1271411B (it) * 1993-09-14 1997-05-28 Zambon Spa Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare
IT1274673B (it) * 1994-04-14 1997-07-24 Zambon Spa Derivati dell'acido fosfonico utili nel trattamento delle malattie car.iovascolari
IT1270260B (it) * 1994-06-21 1997-04-29 Zambon Spa Derivati dell'acido fosfonico ad attivita' inibitrice delle metallopeptidasi
IT1271009B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del benzopirano e del benzotiopirano attivi sul sistema cardiovascolare
IT1271007B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del 2-ammino-1,2,3,4-tetraidronaftalene attivi sul sistema cardiovascolare
IT1271008B (it) * 1994-09-13 1997-05-26 Zambon Spa Derivati del 2-ammino-1,2,3,4-tetraidro-naftalene attivi sul sistema cardiovascolare
IT1273455B (it) * 1995-01-27 1997-07-08 Zambon Spa Derivati tiolici ad attivita' inibitrice delle metallopeptidasi
IT1276710B1 (it) * 1995-06-14 1997-11-03 Zambon Spa Derivati dell'acido fosfinico ad attivita' inibitrice delle metallopeptidasi
GB9625455D0 (en) * 1996-12-07 1997-01-22 Glaxo Group Ltd Process for resolving mixtures of carbocyclic steroisomers
IT1289980B1 (it) * 1997-02-26 1998-10-19 Zambon Spa Derivati idrossimetilici del 2-ammino-1,2,3,4-tetraidronaftalene attivi in campo cardiovascolare
MX2011005979A (es) 2008-12-09 2011-06-27 Interquim Sa Procedimiento de obtencion de (6s)-(-)-5,6,7,8-tetrahidro-6-[propi l-(2-tienil)etil]amino-1-naftol(rotigotina).

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0072061B1 (en) * 1981-08-05 1985-05-15 FISONS plc Amine derivatives, processes for their production and pharmaceutical compositions containing them
EP0375668A3 (en) * 1983-10-25 1990-10-17 FISONS plc Phenylethylamines, process for their preparation and compositions containing them
IT1224405B (it) * 1987-12-23 1990-10-04 Simes Composti attivi sul sistema cardiovascolare

Also Published As

Publication number Publication date
US5407956A (en) 1995-04-18
MD1449G2 (ro) 2000-12-31
PL171844B1 (pl) 1997-06-30
PL172056B1 (pl) 1997-07-31
JP3231775B2 (ja) 2001-11-26
ITMI920608A0 (it) 1992-03-17
FI935066A0 (fi) 1993-11-16
MD960271A (ro) 1997-09-30
OA09843A (en) 1994-08-15
NZ249845A (en) 1996-03-26
ATE137737T1 (de) 1996-05-15
ES2087729T3 (es) 1996-07-16
US5451608A (en) 1995-09-19
DK0585440T3 (da) 1996-06-10
GR3020419T3 (en) 1996-10-31
WO1993019036A1 (en) 1993-09-30
NO180230B (no) 1996-12-02
IT1254521B (it) 1995-09-25
CA2102490C (en) 2004-06-08
HUT68936A (en) 1995-08-28
EP0585440A1 (en) 1994-03-09
DE69302544D1 (de) 1996-06-13
NO180230C (no) 1997-03-12
AU3747893A (en) 1993-10-21
FI935066A (fi) 1993-11-16
KR100283945B1 (ko) 2001-03-02
HU211517A9 (en) 1995-11-28
AU650201B2 (en) 1994-06-09
CA2102490A1 (en) 1993-09-18
RU2120435C1 (ru) 1998-10-20
NO934160L (no) 1993-11-17
JPH06507920A (ja) 1994-09-08
NO934160D0 (no) 1993-11-17
EP0585440B1 (en) 1996-05-08
ITMI920608A1 (it) 1993-09-17
DE69302544T2 (de) 1996-09-19

Similar Documents

Publication Publication Date Title
AU683442B2 (en) Aminoacid derivates, medicaments containing these compounds and process for preparing the same
HUT51269A (en) Process for producing benzimidazole derivatives and pharmaceutical compositions comprising same
HU903094D0 (en) Process for the preparation of antiphlogistic amino-phenol derivatives
MD1449F1 (ro) Derivati ai 2-amino-1,2,3,4-tetrahidronaftalinei cu actiune asupra sistemului cardiovascular, procedeu de obtinere a acestora si compozitii farmaceutice care ii contin
ES8506615A1 (es) Un procedimiento para la preparacion de carboxamidas
IL132599A0 (en) Substituted 3,3-diamino-2-propenenitriles their preparation and use
FI971039A (fi) Sydän-verisuonijärjestelmään aktiivisesti vaikuttavat 2-amino-1,2,3,4-tetrahydronaftaleenijohdannaiset
ES2027550A6 (es) Procedimiento para preparar derivados de glicerol.
MD1738F2 (ro) Sare de diclavulanat, procedeu de obţinere şi compoziţie farmaceutică pe baza ei
AU3750085A (en) Preparation of 3-phenyl alanines derivatives
HK1005878A1 (en) 17B-aryl and 17B-heterocyclyl-5-beta 14-beta-andostane derivatives active on the cardiovascular system processes for their preparation and pharmaceutical compositions containing same
HUT44515A (en) Process for producing isoquinolinol compounds of heart activity increasing, phosphodiesterase iii inhibiting and/or renal vasodilating activity and pharmaceutical composition containing them
GR3025064T3 (en) New hydrazino and hydroxyamino-14beta-hydroxyandrostane derivatives active on the cardio-vascular system, processes for their preparation and pharmaceutical compositions containing same
MX9600165A (es) 3-alcoxicarbonil-tiadiazinonas, proceso para su preparacion y composiciones farmaceuticas que las contienen.
ATE69609T1 (de) Cardiotonische imidazolylphenylpyrrol-2-one.
JO1519B1 (en) New compounds (new benzimidazole derivatives are effective as ulcers)
CA2235967A1 (en) Diarylethylene metallocene derivatives, their processes of preparation and pharmaceutical compositions containing said derivatives
MY105843A (en) Glycerol derivatives, a preparation process of the same and therapeutical compositions containing them.

Legal Events

Date Code Title Description
PD99 Pending application