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PL2152690T3 - Pirydylo piperydynowi antagoniści receptora oreksyny - Google Patents

Pirydylo piperydynowi antagoniści receptora oreksyny

Info

Publication number
PL2152690T3
PL2152690T3 PL08754659T PL08754659T PL2152690T3 PL 2152690 T3 PL2152690 T3 PL 2152690T3 PL 08754659 T PL08754659 T PL 08754659T PL 08754659 T PL08754659 T PL 08754659T PL 2152690 T3 PL2152690 T3 PL 2152690T3
Authority
PL
Poland
Prior art keywords
receptor antagonists
orexin receptor
pyridyl piperidine
pyridyl
compounds
Prior art date
Application number
PL08754659T
Other languages
English (en)
Inventor
Michael J Breslin
Paul J Coleman
Christopher D Cox
John D Schreier
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of PL2152690T3 publication Critical patent/PL2152690T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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PL08754659T 2007-05-23 2008-05-22 Pirydylo piperydynowi antagoniści receptora oreksyny PL2152690T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93145807P 2007-05-23 2007-05-23
PCT/US2008/006563 WO2008147518A1 (en) 2007-05-23 2008-05-22 Pyridyl piperidine orexin receptor antagonists
EP08754659A EP2152690B1 (en) 2007-05-23 2008-05-22 Pyridyl piperidine orexin receptor antagonists

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JP2013502447A (ja) 2009-08-24 2013-01-24 グラクソ グループ リミテッド 睡眠障害の治療のためのオレキシン受容体アンタゴニストとしての５−メチル−ピペリジン誘導体

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