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BRPI0408681A - compostos, composições farmacêuticas, uso de um derivado da 1,2,3,4-tetraidroisoquinolina, método para tratar ou prevenir doenças, processo para a manufatura de composições farmacêuticas, e, uso de um ou mais compostos - Google Patents

compostos, composições farmacêuticas, uso de um derivado da 1,2,3,4-tetraidroisoquinolina, método para tratar ou prevenir doenças, processo para a manufatura de composições farmacêuticas, e, uso de um ou mais compostos

Info

Publication number
BRPI0408681A
BRPI0408681A BRPI0408681-3A BRPI0408681A BRPI0408681A BR PI0408681 A BRPI0408681 A BR PI0408681A BR PI0408681 A BRPI0408681 A BR PI0408681A BR PI0408681 A BRPI0408681 A BR PI0408681A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
compounds
treating
manufacture
preventing disease
Prior art date
Application number
BRPI0408681-3A
Other languages
English (en)
Inventor
Hamed Aissaoui
Martine Clozel
Thomas Weller
Ralf Koberstein
Thierry Sifferlen
Walter Fischli
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of BRPI0408681A publication Critical patent/BRPI0408681A/pt

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    • C—CHEMISTRY; METALLURGY
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    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
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    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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Abstract

"COMPOSTOS, COMPOSIçõES FARMACêUTICAS, USO DE UM DERIVADO DA 1,2,3,4-TETRAIDROISOQUINOLINA, MéTODO PARA TRATAR OU PREVENIR DOENçAS, PROCESSO PARA A MANUFATURA DE COMPOSIçõES FARMACêUTICAS, E, USO DE UM OU MAIS COMPOSTOS". A invenção refere-se a novos derivados de acetamida de Fórmula (I) e seu uso como ingredientes ativos, na preparação de composições farmacêuticas. A invenção também diz respeito a aspectos relacionados, incluindo processos para a preparação de tais compostos, composições farmacêuticas contendo um ou mais desses compostos e, especialmente, seu uso como antagonistas do receptor da orexina.
BRPI0408681-3A 2003-03-26 2004-03-23 compostos, composições farmacêuticas, uso de um derivado da 1,2,3,4-tetraidroisoquinolina, método para tratar ou prevenir doenças, processo para a manufatura de composições farmacêuticas, e, uso de um ou mais compostos BRPI0408681A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP0303143 2003-03-26
PCT/EP2004/003057 WO2004085403A1 (en) 2003-03-26 2004-03-23 Tetrahydroisoquinolyl acetamide derivatives for use as orexin receptor antagonists

Publications (1)

Publication Number Publication Date
BRPI0408681A true BRPI0408681A (pt) 2006-03-28

Family

ID=33040878

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0408681-3A BRPI0408681A (pt) 2003-03-26 2004-03-23 compostos, composições farmacêuticas, uso de um derivado da 1,2,3,4-tetraidroisoquinolina, método para tratar ou prevenir doenças, processo para a manufatura de composições farmacêuticas, e, uso de um ou mais compostos

Country Status (14)

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