[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

PL1966217T3 - Nowe, acykliczne podstawione pochodne furopirymidyny i ich zastosowanie do leczenia schorzeń sercowonaczyniowych - Google Patents

Nowe, acykliczne podstawione pochodne furopirymidyny i ich zastosowanie do leczenia schorzeń sercowonaczyniowych

Info

Publication number
PL1966217T3
PL1966217T3 PL06829427T PL06829427T PL1966217T3 PL 1966217 T3 PL1966217 T3 PL 1966217T3 PL 06829427 T PL06829427 T PL 06829427T PL 06829427 T PL06829427 T PL 06829427T PL 1966217 T3 PL1966217 T3 PL 1966217T3
Authority
PL
Poland
Prior art keywords
novel
cardiovascular diseases
treating cardiovascular
acyclic substituted
furopyrimidine derivatives
Prior art date
Application number
PL06829427T
Other languages
English (en)
Inventor
Thomas Lampe
Eva-Maria Becker
Raimund Kast
Hartmut Beck
Mario Jeske
Joachim Schuhmacher
Friederike Stoll
Martina Klein
Metin Akbaba
Andreas Knorr
Johannes-Peter Stasch
Lars Bärfacker
Alexander Hillisch
Gunter Karig
Mark Meininghaus
Karl-Heinz Schlemmer
Rudolf Schohe-Loop
Original Assignee
Bayer Ip Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ip Gmbh filed Critical Bayer Ip Gmbh
Publication of PL1966217T3 publication Critical patent/PL1966217T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL06829427T 2005-12-21 2006-12-08 Nowe, acykliczne podstawione pochodne furopirymidyny i ich zastosowanie do leczenia schorzeń sercowonaczyniowych PL1966217T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102005061170A DE102005061170A1 (de) 2005-12-21 2005-12-21 Neue, acyclisch substituierte Furopyrimidin-Derivate und ihre Verwendung
PCT/EP2006/011826 WO2007079862A1 (de) 2005-12-21 2006-12-08 Neue, acyclisch substituierte furopyrimidin-derivate und ihre verwendung zur behandlung von kardiovaskulären erkrankungen
EP06829427.1A EP1966217B1 (de) 2005-12-21 2006-12-08 Neue, acyclisch substituierte furopyrimidin-derivate und ihre verwendung zur behandlung von kardiovaskulären erkrankungen

Publications (1)

Publication Number Publication Date
PL1966217T3 true PL1966217T3 (pl) 2013-09-30

Family

ID=37876878

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06829427T PL1966217T3 (pl) 2005-12-21 2006-12-08 Nowe, acykliczne podstawione pochodne furopirymidyny i ich zastosowanie do leczenia schorzeń sercowonaczyniowych

Country Status (32)

Country Link
US (1) US8183246B2 (pl)
EP (1) EP1966217B1 (pl)
JP (1) JP5254032B2 (pl)
KR (1) KR101429777B1 (pl)
CN (1) CN101384603B (pl)
AR (1) AR058108A1 (pl)
AU (1) AU2006334856B2 (pl)
BR (1) BRPI0620317A2 (pl)
CA (1) CA2633701C (pl)
CR (1) CR10092A (pl)
DE (1) DE102005061170A1 (pl)
DK (1) DK1966217T3 (pl)
DO (1) DOP2006000280A (pl)
EC (1) ECSP088569A (pl)
ES (1) ES2418855T3 (pl)
GT (1) GT200800117A (pl)
HK (1) HK1130054A1 (pl)
IL (1) IL192062A0 (pl)
MA (1) MA30039B1 (pl)
NO (1) NO20082986L (pl)
NZ (1) NZ569214A (pl)
PE (1) PE20071168A1 (pl)
PL (1) PL1966217T3 (pl)
PT (1) PT1966217E (pl)
RU (1) RU2454419C2 (pl)
SV (1) SV2009002953A (pl)
TN (1) TNSN08279A1 (pl)
TW (1) TWI405764B (pl)
UA (1) UA94080C2 (pl)
UY (1) UY30046A1 (pl)
WO (1) WO2007079862A1 (pl)
ZA (1) ZA200805385B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007019691A1 (de) * 2007-04-26 2008-10-30 Bayer Healthcare Ag Verwendung von acyclisch substituierten Furopyrimidin-Derivaten zur Behandlung der pulmonalen arteriellen Hypertonie
DE102007027799A1 (de) * 2007-06-16 2008-12-18 Bayer Healthcare Ag Substituierte Furopyrimidine und ihre Verwendung
DE102007051762A1 (de) * 2007-10-30 2009-05-07 Bayer Healthcare Ag Substituierte Pyrrolotriazine und ihre Verwendung
DE102007054786A1 (de) * 2007-11-16 2009-05-20 Bayer Healthcare Ag Trisubstituierte Furopyrimidine und ihre Verwendung
US9505772B2 (en) 2012-05-10 2016-11-29 Takeda Pharmaceutical Company Limited Aromatic ring compound
WO2013168759A1 (ja) 2012-05-10 2013-11-14 武田薬品工業株式会社 芳香環化合物
KR102590848B1 (ko) 2016-12-28 2023-10-19 다트 뉴로사이언스, 엘엘씨 Pde2 억제제로서 치환된 피라졸로피리미디논 화합물
US11434247B1 (en) 2017-11-27 2022-09-06 Dart Neuroscience Llc Substituted furanopyrimidine compounds as PDE1 inhibitors
EP4306529A3 (en) 2019-05-13 2024-04-10 Relay Therapeutics, Inc. Fgfr inhibitors and methods of use thereof
KR102094337B1 (ko) 2019-10-01 2020-03-27 안문호 금속이물질 제거장치

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577420A (en) * 1968-01-05 1971-05-04 Pfizer Certain 4-aminofuro(2,3-d)pyrimidines
EP1018514B1 (en) 1998-07-22 2004-05-12 Daiichi Suntory Pharma Co., Ltd. NF-$g(k)B INHIBITORS CONTAINING INDAN DERIVATIVES AS THE ACTIVE INGREDIENT
EP1181296A1 (en) 1999-06-03 2002-02-27 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
HUP0104841A3 (en) 1999-09-17 2002-07-29 Daiichi Suntory Pharma Co Ltd Medicaments containing benzoquinone- or condensed pyrimidine derivatives as active ingredient for treating of myocarditis, dilated cardiomyopathy and cardiac insufficiency
CA2449188A1 (en) 2001-05-14 2002-11-21 Novartis Ag Oxazolo-and furopyrimidines and their use in medicaments against tumors
DE10141212A1 (de) * 2001-08-22 2003-03-06 Bayer Ag Neue 4-Aminofuropyrimidine und ihre Verwendung
EP1425284A2 (en) 2001-09-11 2004-06-09 Smithkline Beecham Corporation Furo- and thienopyrimidine derivatives as angiogenesis inhibitors
DE10148883A1 (de) 2001-10-04 2003-04-10 Merck Patent Gmbh Pyrimidinderivate
US20030225098A1 (en) 2002-03-21 2003-12-04 Hirst Gavin C. Kinase inhibitors
KR20050091462A (ko) 2004-03-12 2005-09-15 한국과학기술연구원 푸로피리미딘 화합물 및 이를 포함하는 ｄｄｒ2 티로신키나아제 활성 저해제
AU2005252440A1 (en) 2004-06-10 2005-12-22 Xention Discovery Limited Furanopyrimidine compounds effective as potassium channel inhibitors
JP2008505084A (ja) 2004-06-29 2008-02-21 アムゲン インコーポレイティッド フラノピリミジン

Also Published As

Publication number Publication date
CA2633701A1 (en) 2007-07-19
JP5254032B2 (ja) 2013-08-07
NZ569214A (en) 2011-07-29
US20090318475A1 (en) 2009-12-24
TWI405764B (zh) 2013-08-21
PE20071168A1 (es) 2008-02-07
DK1966217T3 (da) 2013-08-05
CN101384603A (zh) 2009-03-11
RU2454419C2 (ru) 2012-06-27
AU2006334856B2 (en) 2013-04-04
PT1966217E (pt) 2013-07-12
ES2418855T3 (es) 2013-08-16
ZA200805385B (en) 2009-10-28
AU2006334856A1 (en) 2007-07-19
IL192062A0 (en) 2008-12-29
CN101384603B (zh) 2012-08-01
NO20082986L (no) 2008-07-02
JP2009520713A (ja) 2009-05-28
SV2009002953A (es) 2009-04-28
KR101429777B1 (ko) 2014-08-19
AR058108A1 (es) 2008-01-23
RU2008129363A (ru) 2010-01-27
US8183246B2 (en) 2012-05-22
EP1966217B1 (de) 2013-05-08
UY30046A1 (es) 2007-07-31
ECSP088569A (es) 2008-08-29
CA2633701C (en) 2014-05-27
WO2007079862A1 (de) 2007-07-19
MA30039B1 (fr) 2008-12-01
TNSN08279A1 (en) 2009-10-30
BRPI0620317A2 (pt) 2011-11-08
KR20080081323A (ko) 2008-09-09
EP1966217A1 (de) 2008-09-10
CR10092A (es) 2008-10-08
HK1130054A1 (en) 2009-12-18
UA94080C2 (ru) 2011-04-11
DOP2006000280A (es) 2007-07-31
TW200745132A (en) 2007-12-16
DE102005061170A1 (de) 2007-07-05
GT200800117A (es) 2009-12-16

Similar Documents

Publication Publication Date Title
ZA200805385B (en) Novel, acyclic substituted furopyrimidine derivatives and use thereof for treating cardiovascular diseases
IL179424A0 (en) Substituted oxazole -benzoisothiazole dioxide derivatives, process for their preparation and their use
ZA200606974B (en) Substituted 1,2,3,4-tetrahydrolsoquinoline derivatives
IL182837A0 (en) Methods, assays and compositions for treating retinol-related diseases
SI1928882T1 (sl) (s)-n-metilnaltrekson, postopek za njega sintezo in njega farmacevtska uporaba
IL184901A0 (en) 2,4-diamino-pyridopyrimidine derivatives and their use as mtor inhibitors
EP1951680A4 (en) NOVEL 2-AMINOPYRIMIDINONE DERIVATIVES AND THEIR USE
IL191655A0 (en) Novel compounds, their preparation and use
HK1105966A1 (en) New 4-benzylidene-piperidin derivatives
IL177204A0 (en) Novel 4-benzimidazol -2-ylpyridazin -3- one derivatives
HK1101638A1 (en) New pyridothienopyrimidine derivatives
IL184314A0 (en) Substituted 4-phenyltetrahydroisoquinolines, methods for producing them, their use as drug, and drug containing them
ZA200706672B (en) 2,4-Diamino-pyridopyrimidine derivatives and their use as mTOR inhibitors
IL179068A0 (en) Substituted enaminones, their derivatives and uses thereof
IL183141A0 (en) New pyridothienopyrimidine derivatives
SI2020410T1 (sl) Derivati pirido(2,3-d)pirimidina, njihova priprava, njihova terapevtska uporaba
IL182739A0 (en) Acylatednonadepsipeptides used as lysobactin derivatives
IL177662A0 (en) Novel pyrrolidine-3,4-dicarboxamide derivatives
IL182538A0 (en) 1,5-diheterocycle-1h-triazole derivative
HK1100946A1 (en) 1-a-HALO-2,2-DIFLUORO-2-DEOXY-D-RIBOFURANOSE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF
IL186851A0 (en) Styrylsulfonamides, their manufacture and use as pharmaceutical agents
TWI367222B (en) Aminoquinoxaline compounds and polyaminoquinoxaline compounds, and use thereof
PL1786759T3 (pl) Nowe pochodne 3,5-seko-4-norcholestanowe i ich zastosowanie
IL190045A0 (en) Use of c3-c10 17 alfa-esters of 9,11-dehydrocortexolone as anti-gonadotrophic agents
IL187419A0 (en) Heteroarylethenyl derivatives, their manufacture and use as pharmaceutical agents