KR101124969B1 - Cosmetic composition for skin miosture - Google Patents

Abstract

The present invention relates to a cosmetic composition for moisturizing the skin. More specifically, the present invention relates to a cosmetic composition having excellent skin moisturizing effect by containing birch sap, sugar cane extract and thyme extract.

Moisturizing, Thyme, Sugar cane, Birch sap, Cosmetics

Description

Cosmetic composition for skin moisturizing {Cosmetic composition for skin miosture}

The present invention relates to a cosmetic composition for moisturizing the skin. More specifically, the present invention relates to a cosmetic composition having excellent skin moisturizing effect by containing birch sap, sugar cane extract and thyme extract.

The skin is the organ located at the outermost part of the human body, protecting the human body from external physical and chemical stimuli and performing important functions such as moisture control, immune response, body temperature control, and waste secretion. Looking at the constituent tissue of the skin, the epidermis, the dermis, and the subcutaneous fat layer, the stratum corneum located in the outermost layer of the epidermis plays an important role of skin moisturizing. In other words, the stratum corneum inhibits the loss of water and electrolytes through the skin and plays a key role in maintaining normal physiological activity of the skin by acting as a defense against external stimuli such as microorganisms and ultraviolet rays.

Moisturizing of the skin is closely related to the moisture content of the stratum corneum. The moisture content of the epidermal layer is about 70% in the basal and polar layers, 30-50% in the granular layer, and 15-30% in the stratum corneum (Journal of Investigative Dermatology, 116, 434442, 2001). People who complain of dry skin are known to contain less than 10% water in the stratum corneum. Therefore, the moisture content of the stratum corneum plays a very important role in moisturizing the skin, and it is known to retain moisture in the stratum corneum through three mechanisms: skin barrier, sebum, and natural moisturizing factor (NMF). The stratum corneum is likened to a "bricks and mortal model" where keratinocytes play the role of bricks in the stratum corneum and intercellular lipids act as a plaster (Elias PM et al, Int. J. Dermatol. 20: 1 -19 (1981)). The keratinocytes of the stratum corneum are composed of keratin proteins and are involved in structural firmness to the skin, and the intercellular lipids of the stratum corneum are composed of ceramide, cholesterol, and free fatty acids, which inhibit the evaporation of moisture in the body. Doing. In addition, sebum secreted from sebaceous glands form a film on the surface of the stratum corneum to prevent evaporation of moisture. Natural Moisturizing Factor (NMF) is present in the stratum corneum, resulting in urocanic acid, pyrrolidone carboxylic aicd, amino acid, lactate and urea. And the like. This NMF is a water-soluble substance that binds to and retains moisture, helping to maintain proper moisture.

However, due to environmental changes, stress, excessive face wash, and aging, the stratum corneum does not have normal moisture and forms dry skin, resulting in dull skin tone and rough skin. Therefore, polyols, amino acids, sugars and the like have been used in cosmetics for moisturizing the skin. However, in a dry environment, rather than taking away the moisture of the skin increases the dryness of the skin, there is a problem that feels sticky in high humidity.

In humans, where the wind is strong and the relative humidity is low, such as in winter, the moisture of the skin evaporates quickly to the outside, resulting in dry skin, rough skin, and itching. On the contrary, in places with high temperature and high relative humidity, such as summer, sweat does not evaporate and stays on the skin and feels sticky and moist.

Conventionally, when a formulation containing a skin lipid component as a skin moisturizer is used for skin barrier recovery and reinforcement, when a moisturizer is developed by applying a natural moisturizing factor or polyols such as glycerin, butylene glycol, and keratinocyte differentiation, There are many ways to promote the development of skin moisturizers. However, it is difficult to expect a moisturizing effect continuously in the summer and winter, or in places where the relative humidity difference between indoors and outdoors is severe.

Accordingly, the present inventors have studied a cosmetic composition that can maintain constant skin moisture at all times even with environmental changes such as relative humidity, temperature, and wind. As a result, when the sugarcane extract and birch sap are mixed, the moisture retention ability is very high. It has been found to be excellent and to have an effect of suppressing a decrease in moisture. In addition, when the thyme extract (Korean Patent No. 10-0878026), which is excellent in improving skin moisture retention ability, is found to further increase skin moisturizing power, the present invention has been completed.

The present invention may include the following means to solve the above object.

Skin moisturizing cosmetic composition according to the present invention contains birch sap and sugar cane extract as an active ingredient.

The cosmetic composition is characterized in that it further contains a thyme extract.

The birch sap is 0.001% to 10.0% by weight relative to the total weight of the cosmetic composition, the sugar cane extract is 0.001% to 30.0% by weight relative to the total weight of the cosmetic composition, the thyme extract is the total weight of the cosmetic composition It is characterized by containing from 0.001% to 30.0% by weight relative to.

The composition for moisturizing the skin, characterized in that it has a formulation selected from the group consisting of softening water, nourishing lotion, nourishing cream, massage cream, essence, eye cream, cleansing cream, cleansing foam, cleansing water, pack, spray and powder Cosmetic composition

It was observed that birch sap and sugarcane extract maintain a constant moisture even when the humidity changes outside, and it was confirmed that even the hypertonic condition inhibits the loss of water to protect the cells and protects the sugarcane extract and birch sap. When mixed, it was found that the moisture retention ability was very excellent in the dry environment and the effect of suppressing the reduction of moisture was also applied, and when the thyme extract (Korean Patent No. 10-0878026) having excellent skin moisture retention ability was applied together, The skin moisturizing effect was greatly improved.

In order to achieve the above object, the present invention relates to a cosmetic composition for improving skin moisturizing by containing birch sap, sugarcane extract, thyme extract as an active ingredient as an active ingredient.

Hereinafter, the present invention will be described in detail.

Birch, which is an active ingredient of the present invention, is a deciduous tree belonging to the birch family, and grows up to 25 meters in height and 1 m in diameter, and the distribution area is grown in Korea, Japan, China, and the like. Birch has long been used as a medicinal herb, and has been known to be effective for nephritis, edema, gastritis and neuralgia. Birch sap is harvested in early spring and has been used in the private sector for diuresis, appetite promotion, nerve stabilization, and gastrointestinal diseases.

Sugarcane, an active ingredient of the present invention, is a perennial herb of the plant and its origin is India, and the distribution region is grown in Cuba, Brazil, the Philippines, Mexico, Hawaii, etc. as a tropical region. It grows up to 2-6m in height and contains a lot of sugar and is used for making sugar. Recently, ethanol fermented from sugar cane is also used as bioenergy.

Thyme, the active ingredient of the present invention is a plant of the family Lamiaceae grows in high mountain tops such as Korea, Japan, China, Mongolia, India, and rocky seashore. Its height is 3 ～ 15cm, and main stem spreads out on the ground, young branches stand at an angle, and scent. In the private sector, thyme was used as a medicine, and it has been used for stomach pain, whooping cough, sedatives, and indigestion.

The birch sap used in the present invention was collected in the early spring of Gangwon-do area, which is a clean area, and the sap was filtered and stored in a refrigerator.

Sugar cane extract in the present invention was purchased from Ajinomoto (Japan).

In the present invention, the thyme extract is most preferably extracted by adding ethanol to a polar solvent selected from water, a lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof. In addition, the thyme extract according to the present invention can be prepared as follows. Wash thyme with water and dry in the shade. Dry thyme is placed in the extraction container, an appropriate amount of extraction solvent is added and extracted for a certain time at a suitable temperature. The extract can be filtered and concentrated using a vacuum rotary evaporator or the like. As the extraction solvent, a polar solvent selected from water (purified water), a lower alcohol having 1 to 4 carbon atoms or a mixed solvent thereof may be used, and preferably ethanol is used. The amount of the extraction solvent is 2 to 10 times the dry weight of the herbal medicine. The extraction temperature is 30 ~ 90 ℃, more preferably 60 ~ 80 ℃, most preferably maintained at about 60 ℃ is most effective in the prevention of rot, discoloration and odor. The extraction time is 5 to 20 hours, preferably 10 hours. After obtaining the thyme extract, the solids may be removed using a filter paper, the suspension may be centrifuged, and the supernatant may be filtered under reduced pressure. The filtered extract may be concentrated under reduced pressure at 20 ~ 100 ℃, preferably 50 ~ 70 ℃ with a vacuum rotary concentrator.

On the other hand, the birch sap is characterized in that it contains 0.001 ~ 10.0% by weight based on the total weight of the cosmetic composition. When the content of the birch sap is less than 0.001% by weight, the effect is insignificant, and when it exceeds 10.0% by weight it is difficult to expect the effect.

The sugar cane extract is characterized in that it contains 0.001 to 30.0% by weight, when the cosmetic composition of the present invention contains the extract in less than 0.001 weight, the effect of the cosmetic composition is insignificant and may exceed 30.0% by weight. In that case, it is difficult to expect the effect.

The content of the thyme extract is characterized in that it contains 0.001 to 30.0% by weight, when the cosmetic composition of the present invention comprises the extract in less than 0.001 weight, the effect of the cosmetic composition is insignificant and exceeds 30.0% by weight , It is difficult to expect the effect.

In addition to birch sap, sugar cane extract and thyme extract, which are the active ingredients included in the cosmetic composition of the present invention, including components commonly used in cosmetic compositions, such as antioxidants, stabilizers, solubilizers, vitamins, pigments and flavorings Conventional inclusion agents such as, and the like.

Hereinafter, the present invention will be described in more detail with reference to the following examples. These examples are only for illustrating the present invention in more detail, and the scope of the present invention is not limited to these embodiments according to the gist of the present invention to those skilled in the art to which the present invention pertains. Will be self explanatory.

Preparation Example 1 Preparation of Thyme Extract

50 g of thyme was finely crushed in a crusher and immersed in 200 ml of 50% ethanol and warmed in an 80 ° C. water bath for 2 hours or more. The obtained extract was cooled to room temperature and filtered through a filter paper to give a filtrate. Ethanol was evaporated from the filtrate using nitrogen, concentrated, and then dissolved in 10% ethanol to prepare an extract.

Experimental Example 1 Evaluation of Water Retention Capacity of Birch Sap and Sugar Cane Extract

Birch sap, sugar cane extract, birch and sugar cane extract mixture, glycerin and 1,3-butylene glycol were prepared in purified water in the form of an aqueous solution, and then dried at a constant temperature (25 ° C) (humidity of 20%) and humid. The water retention capacity under the conditions (80% humidity) was measured. 25 g of each aqueous solution was placed in a petri dish and placed in dry and wet conditions, respectively, and the weight change was measured. Weighed twice a day for 3 days (10 am and 3 pm). The results of this experiment are shown in Tables 1 and 2 below.

* Dry conditions time Birch sap
(10.0%) Sugar Cane Extract
(10.0%) Mixed solution of birch sap and sugar cane extract
(5.0% + 5.0%) glycerin
(10.0%) 1,3-butylene glycol
(10.0%) 1st morning 25.24 25.10 25.38 25.33 25.17 1st afternoon 25.22 25.06 25.13 24.97 23.95 2 days morning 25.10 24.90 25.07 24.47 23.10 2nd afternoon 24.93 24.81 24.97 22.71 22.64 3 day morning 24.80 24.07 24.94 21.97 21.02 3rd afternoon 23.79 23.77 24.08 20.31 19.93

* Humid conditions time Birch sap
(10.0%) Sugar Cane Extract
(10.0%) Mixed solution of birch sap and sugar cane extract
(5.0% + 5.0%) glycerin
(10.0%) 1,3-butylene glycol
(10.0%) 1st morning 25.31 25.16 25.41 25.58 25.19 1st afternoon 25.32 25.22 25.43 26.11 26.05 2 days morning 25.39 25.36 25.50 26.87 26.91 2nd afternoon 25.41 25.45 25.56 26.96 27.09 3 day morning 26.08 26.09 25.68 27.37 28.12 3rd afternoon 26.13 26.14 26.00 28.88 29.37

As can be seen from the results of the experimental example, it was observed that the samples of the birch sap and the sugar cane extract do not lose moisture in the dry environment and do not retain the moisture in high humidity, especially the birch sap and the sugar cane extract In the mixed solution of, it could be confirmed that the moisture was kept constant without significant change even in the external humidity change and the moisture retention was maintained for a long time in the dry condition.

Experimental Example 2 Cytoprotective Effect on Faulty Stress

In order to measure the effect of protecting the cells without losing water even in the hypertonic solution using the birch sap and the sugar cane extract as the active ingredient, the experiment was carried out as follows.

HaCat cells, keratinocytes, were incubated in Dulbecco's modified Eagle's medium (DMEM) medium containing birch sap and sugar cane extract for 24 hours at 37 ° C. and 5% CO ₂ , followed by a medium containing NaCl (400 mosmol per L) and incubated for 16 hours. Then, it was replaced with a medium containing birch sap and sugar cane extract and incubated for 48 hours. After incubation, 5 mg / ml yellow tetrazolium salt (MTT) solution was added, and after 4 hours, the yellow tetrazolium salt solution was removed and dissolved for 10 minutes with dimethyl sulfoxide (DMSO) spectrophotometer (Molecular Devices, USA) Absorbance of 570 nm was measured using a. The results are shown in Table 1 below. Negative controls were treated with nothing, and positive controls were treated with hypertonic medium. The results of this experiment are shown in Table 3 below.

sample Cell survival rate (%) Negative Control 100.0 Positive control group 2.1 Birch sap 1.0% 26.47 Sugarcane Extract 1.0% 24.19 Birch sap 0.5% + Sugarcane extract 0.5% 62.68

As a result of the above experiment, it can be seen that the sample of birch sap and sugarcane extract has a protective effect against the stress of the hypertonic solution, and surprisingly, the sample mixed with birch sap and sugarcane extract It was confirmed that there is an excellent effect.

[Production Example 2]

To Table 4 was prepared a cosmetic composition containing the active ingredient in the form of nutrition cream having a composition ratio.

ingredient Example
(weight%) Comparative Example 1 (% by weight) Comparative Example 2 (wt%) Comparative Example 3 (wt%) Comparative Example 3
(weight%) Birch sap 2.0 6.0 - - - Sugar Cane Extract 2.0 - 6.0 - - Thyme Extract 2.0 - - 6.0 - glycerin 1.0 1.0 1.0 1.0 1.0 Liquid paraffin 10.0 10.0 10.0 10.0 10.0 Polysorbate 60 2.0 2.0 2.0 2.0 2.0 Sorbitan sesquirololeate 1.0 1.0 1.0 1.0 1.0 Squalane 5.0 5.0 5.0 5.0 5.0 Beeswax 10.0 10.0 10.0 10.0 10.0 Triethanolamine 0.5 0.5 0.5 0.5 0.5 Propylene glycol 1.0 1.0 1.0 1.0 1.0 Carboxyl Vinyl Polymer 1.5 1.5 1.5 1.5 1.5 antiseptic a very small amount a very small amount a very small amount a very small amount a very small amount Purified water Balance Balance Balance Balance Balance system 100 100 100 100 100

Experimental Example 3 Skin Moisturizing Evaluation

Moisturizing effect in the stratum corneum was measured using the cosmetics prepared in Examples and Comparative Examples. A survey was conducted on 100 women aged 30-40 who feel dry skin, and the cosmetics prepared in Examples and Comparative Examples 1-4 were applied twice a day to the face and then used for one month. The rate of increase of skin moisturization after 4 weeks was measured using a moisture measuring instrument (corneometer CM825, courage Khazaka electronic GmbH, Germany) at constant temperature and humidity conditions (25 ℃, humidity 45%) before the start of application. The results are shown in Table 5 below, and the results are expressed as average values.

Cosmetics 4 weeks (%) Example 79.4 Comparative Example 1 31.8 Comparative Example 2 30.0 Comparative Example 3 49.3 Comparative Example 4 1.3

As shown in Table 5, as a result of measuring the moisturizing effect of the cosmetics prepared according to Examples and Comparative Examples 1 to 4, when containing birch sap, sugar cane extract, thyme extract, the moisturizing effect is very It was confirmed that excellent.

Hereinafter, as an example of the cosmetic formulation of the present invention, the softening lotion, lotion, essence, massage cream, shampoo and body cleanser containing the active ingredient of the present invention are exemplified, but the formulation of the cosmetic of the present invention is not necessarily limited thereto. .

Formulation Example 1 Flexible Cosmetics

Softening water containing birch sap, sugar cane extract, thyme extract was prepared according to a conventional method.

Raw material name Content (% by weight) Birch sap 2.0 Sugar Cane Extract 2.0 Thyme Extract 2.0 1,3-butylene glycol 5.2 Oleyl alcohol 1.5 ethanol 3.2 Polysorbate 20 3.2 Benzophenone-9 2.0 Carboxyl Vinyl Polymer 1.0 glycerin 3.5 incense a very small amount antiseptic a very small amount Purified water Balance system 100

[Formulation Example 2] Lotion

Lotions containing birch sap, sugar cane extract and thyme extract were prepared according to a conventional method.

Raw material name Content (% by weight) Birch sap 2.0 Sugar Cane Extract 2.0 Thyme Extract 2.0 Cetostearyl alcohol 1.0 Glyceryl Monostearate 0.8 Sorbitan monostearate 0.3 Porofilparaben 0.1 Polysorbate 60 1.0 Mineral oil 5.0 Pyromethicone 3.0 Dimethicone 0.5 Allantoin 0.1 glycerin 5.0 Alcohol 2 Propylene glycol 3.0 incense a very small amount antiseptic a very small amount Purified water Balance system 100

Formulation Example 3 Essence

An essence containing birch sap, sugar cane extract, and thyme extract was prepared according to a conventional method.

Raw material name Content (% by weight) Birch sap 2.0 Sugar Cane Extract 2.0 Thyme Extract 2.0 1,3-butylene glycol 4.0 glycerin 3.0 Allantoin 0.5 Panthenol 0.1 EDTA-2Na 0.01 ethanol 5.0 Triethanolamine 1.5 Squalane 2.0 Beeswax 2.5 Polysorbate 60 3.5 Carboxyl Vinyl Polymer 1.0 Sorbitan sesquioleate 2.5 incense a very small amount antiseptic a very small amount Purified water Balance system 100

Formulation Example 5 Massage Cream

Massage cream containing birch sap, sugar cane extract, thyme extract was prepared according to a conventional method.

Raw material name Content (% by weight) Birch sap 2.0 Sugar Cane Extract 2.0 Thyme Extract 2.0 glycerin 4.0 Vaseline 3.5 Triethanolamine 0.5 Liquid paraffin 24.0 Squalane 3.0 Beeswax 2.1 Tocopheryl acetate 0.1 Polysorbate 60 2.4 Carboxyl Vinyl Polymer 1.0 Sorbitan sesquioleate 2.3 incense a very small amount antiseptic a very small amount Purified water Balance system 100

Formulation Example 6 Shampoo

Shampoo containing birch sap, sugar cane extract, thyme extract was prepared according to a conventional method.

Raw material name Content (% by weight) Birch sap 2.0 Sugar Cane Extract 2.0 Thyme Extract 2.0 Alkyl ether sulfate (30%) 20.0 Alkylamidobetaine (30%) 5.0 Propylene glycol 3.0 Lauramid 4.0 EDTA-2Na 0.1 Polyquaternium-10 0.05 NaCl 0.1 Citric acid 2.4 incense a very small amount antiseptic a very small amount Purified water Balance system 100

Formulation Example 7 Body Cleanser

A body cleanser containing birch sap, sugar cane extract and thyme extract was prepared according to a conventional method.

Raw material name Content (% by weight) Birch sap 2.0 Sugar Cane Extract 2.0 Thyme Extract 2.0 Alkyl ether saccharide (30%) 30.0 Alkyl ether sulfosuccinate (30%) 20.0 Alkylamidobetaine (30%) 5.0 Propylene glycol 5.0 Betaine 5.0 Lauramiddiei 4.0 Cellulose gum 0.05 Hydrolyzed protein 0.1 Citric acid a very small amount NaCl a very small amount incense a very small amount antiseptic a very small amount Purified water Balance system 100

As described above, the birch sap and the sugar cane extract were observed to maintain a constant moisture even when the humidity changes outside. I could confirm that. In addition, when the birch sap and the sugar cane extract containing thyme extract, the skin moisturizing effect was greatly improved.

Claims (4)

A skin moisturizing cosmetic composition for reducing skin irritation containing birch sap and sugarcane extract as an active ingredient. The method of claim 1, wherein the cosmetic composition, Cosmetic composition for skin moisturizing further comprising a thyme extract. According to claim 2, wherein the birch sap is 0.001% to 10.0% by weight relative to the total weight of the cosmetic composition, the sugarcane extract is 0.001% to 30.0% by weight relative to the total weight of the cosmetic composition, the thyme extract is A cosmetic composition for moisturizing skin, comprising 0.001% to 30.0% by weight based on the total weight of the cosmetic composition. The method of claim 2, wherein the cosmetic composition, Skin moisturizing cosmetic, characterized in that it has one formulation selected from the group consisting of softening lotion, nourishing lotion, nourishing cream, massage cream, essence, eye cream, cleansing cream, cleansing foam, cleansing water, pack, spray and powder Composition