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IT1096361B - Dibenzileteri sostituiti terapeuticamente attivi - Google Patents

Dibenzileteri sostituiti terapeuticamente attivi

Info

Publication number
IT1096361B
IT1096361B IT23546/78A IT2354678A IT1096361B IT 1096361 B IT1096361 B IT 1096361B IT 23546/78 A IT23546/78 A IT 23546/78A IT 2354678 A IT2354678 A IT 2354678A IT 1096361 B IT1096361 B IT 1096361B
Authority
IT
Italy
Prior art keywords
bonds
replaced
therapeutically active
therapeutically
active
Prior art date
Application number
IT23546/78A
Other languages
English (en)
Other versions
IT7823546A0 (it
Inventor
Dante Nardi
Elena Massarani
Alberto Tajana
Mario Veronese
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of IT7823546A0 publication Critical patent/IT7823546A0/it
Priority to IT23546/78A priority Critical patent/IT1096361B/it
Priority to PT69537A priority patent/PT69537A/pt
Priority to ZA792015A priority patent/ZA792015B/xx
Priority to DE2917244A priority patent/DE2917244C2/de
Priority to EG250/79A priority patent/EG14345A/xx
Priority to HU79RE645A priority patent/HU182565B/hu
Priority to GR59034A priority patent/GR68396B/el
Priority to AR276430A priority patent/AR219596A1/es
Priority to AT0345079A priority patent/AT372950B/de
Priority to NZ190412A priority patent/NZ190412A/xx
Priority to IL57245A priority patent/IL57245A/xx
Priority to PH22475A priority patent/PH14782A/en
Priority to CA327,426A priority patent/CA1115718A/en
Priority to DK196579A priority patent/DK153838C/da
Priority to YU01122/79A priority patent/YU112279A/xx
Priority to GB7916670A priority patent/GB2025395B/en
Priority to NO791599A priority patent/NO152840C/no
Priority to DD79212866A priority patent/DD143608A5/de
Priority to ES480552A priority patent/ES480552A1/es
Priority to FI791543A priority patent/FI71309C/fi
Priority to CH456979A priority patent/CH639075A5/fr
Priority to JP54060971A priority patent/JPS605592B2/ja
Priority to NLAANVRAGE7903872,A priority patent/NL189255C/xx
Priority to SU792771698A priority patent/SU816399A3/ru
Priority to SE7904319A priority patent/SE444812B/sv
Priority to AU47149/79A priority patent/AU523053B2/en
Priority to FR7912638A priority patent/FR2426047A1/fr
Priority to MX797989U priority patent/MX5927E/es
Priority to IE958/79A priority patent/IE48372B1/en
Application granted granted Critical
Publication of IT1096361B publication Critical patent/IT1096361B/it
Priority to NL930014C priority patent/NL930014I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IT23546/78A 1978-05-18 1978-05-18 Dibenzileteri sostituiti terapeuticamente attivi IT1096361B (it)

Priority Applications (30)

Application Number Priority Date Filing Date Title
IT23546/78A IT1096361B (it) 1978-05-18 1978-05-18 Dibenzileteri sostituiti terapeuticamente attivi
PT69537A PT69537A (fr) 1978-05-18 1979-04-24 Procede pour la preparation d'etheres dibenziliques substitues therapeutiquement actifs
ZA792015A ZA792015B (en) 1978-05-18 1979-04-26 Therapeutically active substituted dibenzyl ehters
DE2917244A DE2917244C2 (de) 1978-05-18 1979-04-27 1-[[2-(2,4-Dichlorphenyl)-2-benzyloxy]-äthyl]-imidazole, Verfahren zu deren Herstellung sowie solche enthaltende Arzneimittel
EG250/79A EG14345A (en) 1978-05-18 1979-04-29 Therapeutically active substituted dibenzyl ethers
HU79RE645A HU182565B (en) 1978-05-18 1979-05-07 Process for producing 4'-substituted-2,4-dichloro-alpha-/imidazole-n-il-methyl/-benzyl ethers
GR59034A GR68396B (it) 1978-05-18 1979-05-07
AR276430A AR219596A1 (es) 1978-05-18 1979-05-07 Procedimiento para la preparacion de derivados de 2,4-dicloro-alpha-(n-imidazolilmetil)-dibencil-eteres
AT0345079A AT372950B (de) 1978-05-18 1979-05-09 Verfahren zur herstellung von 4'-substituierten 2,4-dichlor-alpha-(imidazol-n-ylmethyl)dibenzyl[thern und von deren salzen
NZ190412A NZ190412A (en) 1978-05-18 1979-05-10 2,4-dichloro-a-(n-imidazolyl-methyl)-dibenzyl ethers and pharmaceutical compositions
IL57245A IL57245A (en) 1978-05-18 1979-05-10 Alpha-imidazolyl methyl dibenzyl ethers,their preparation and pharmaceutical compositions comprising therapeutically active substituted dibenzyl ethers
PH22475A PH14782A (en) 1978-05-18 1979-05-10 Therapeutically active substituted dibenzyl ethers,method for preparation thereof and pharmaceutical compositions containing said ethers
CA327,426A CA1115718A (en) 1978-05-18 1979-05-11 Therapeutically active substituted dibenzyl ethers
YU01122/79A YU112279A (en) 1978-05-18 1979-05-14 Process for obtaining substituted dibenzylethers
DK196579A DK153838C (da) 1978-05-18 1979-05-14 Analogifremgangsmaade til fremstilling af 2,4-dichlor-alfa-(n-imidazolylmethyl)-dibenzylethere
GB7916670A GB2025395B (en) 1978-05-18 1979-05-14 Therapeutically active substituted dibenzyl ethers
NO791599A NO152840C (no) 1978-05-18 1979-05-14 Fremgangsmaate for fremstilling av dibenzyletere.
DD79212866A DD143608A5 (de) 1978-05-18 1979-05-14 Verfahren zur herstellung von 4'-substituierten 2,4-dichlor-alpha-(imidazol-n-ylmethyl)-dibenzylaethern
ES480552A ES480552A1 (es) 1978-05-18 1979-05-14 Un procedimiento para la preparacion de eteres dibencilicos substituidos.
FI791543A FI71309C (fi) 1978-05-18 1979-05-15 Foerfarande foer framstaellning av terapeutiskt anvaendbara 2,-diklor-4'-fenyl- och -4'-fenyltio-alfa-(n-imidazolylmety l)ibensyletrar
NLAANVRAGE7903872,A NL189255C (nl) 1978-05-18 1979-05-16 2,4-dichloor-alfa-(n-imidazolylmethyl)-dibenzyletherderivaat, alsmede een deze verbinding omvattend farmaceutisch preparaat.
JP54060971A JPS605592B2 (ja) 1978-05-18 1979-05-16 置換ジベンジルエ−テル類、その製造法及びこれを含む抗菌剤
CH456979A CH639075A5 (fr) 1978-05-18 1979-05-16 Ethers dibenzyliques substitues actifs sur le plan therapeutique.
SU792771698A SU816399A3 (ru) 1978-05-18 1979-05-17 Способ получени замещенных дибензиловыхэфиРОВ или иХ КиСлОТНО-АддиТиВНыХ СОлЕй
SE7904319A SE444812B (sv) 1978-05-18 1979-05-17 Imidazol-derivat och syraadditionssalter derav, forfarande for deras framstellning samt farmaceutisk komposition innehallande imidizol-derivaten
AU47149/79A AU523053B2 (en) 1978-05-18 1979-05-17 Therapeutically active substituted dibenzyl ethers
FR7912638A FR2426047A1 (fr) 1978-05-18 1979-05-17 Nouveaux ethers benzyliques substitues de 1-(2,4-dichlorophenyl)-2-(imidazolyl)ethanol, utiles notamment comme antifongiques et leur procede de preparation
MX797989U MX5927E (es) 1978-05-18 1979-05-18 Procedimiento mejorado para la preparacion de eteres dibencilicos substituidos
IE958/79A IE48372B1 (en) 1978-05-18 1979-08-08 Therapeutically active imidazolylmethyl-substituted dibenzyl ethers
NL930014C NL930014I2 (nl) 1978-05-18 1993-02-19 2,4-Dichloor-alpha(N-imidazolylmethyl)-dibenzyletherderivaat, alsmede een deze verbinding omvattend farmaceutisch preparaat.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT23546/78A IT1096361B (it) 1978-05-18 1978-05-18 Dibenzileteri sostituiti terapeuticamente attivi

Publications (2)

Publication Number Publication Date
IT7823546A0 IT7823546A0 (it) 1978-05-18
IT1096361B true IT1096361B (it) 1985-08-26

Family

ID=11208025

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23546/78A IT1096361B (it) 1978-05-18 1978-05-18 Dibenzileteri sostituiti terapeuticamente attivi

Country Status (29)

Country Link
JP (1) JPS605592B2 (it)
AR (1) AR219596A1 (it)
AT (1) AT372950B (it)
AU (1) AU523053B2 (it)
CA (1) CA1115718A (it)
CH (1) CH639075A5 (it)
DD (1) DD143608A5 (it)
DE (1) DE2917244C2 (it)
DK (1) DK153838C (it)
EG (1) EG14345A (it)
ES (1) ES480552A1 (it)
FI (1) FI71309C (it)
FR (1) FR2426047A1 (it)
GB (1) GB2025395B (it)
GR (1) GR68396B (it)
HU (1) HU182565B (it)
IE (1) IE48372B1 (it)
IL (1) IL57245A (it)
IT (1) IT1096361B (it)
MX (1) MX5927E (it)
NL (2) NL189255C (it)
NO (1) NO152840C (it)
NZ (1) NZ190412A (it)
PH (1) PH14782A (it)
PT (1) PT69537A (it)
SE (1) SE444812B (it)
SU (1) SU816399A3 (it)
YU (1) YU112279A (it)
ZA (1) ZA792015B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1155853A (en) * 1980-06-06 1983-10-25 Joseph A. Martin Imidazole derivatives and preparation thereof
FR2541114B1 (fr) * 1983-02-23 1986-04-11 Sanofi Sa Compositions pharmaceutiques antifongiques utilisables par voie orale contenant de l'omoconazole
DK79184A (da) * 1983-02-23 1984-08-24 Sanofi Sa Fungicide farmaceutiske midler indeholdende et imidazolderivat
CA1250586A (en) * 1984-02-02 1989-02-28 Manuel Raga 1h-imidazole derivatives and process for their production
DE3413365A1 (de) * 1984-04-09 1985-12-19 Merz + Co GmbH & Co, 6000 Frankfurt Substituierte phenylethylderivate, verfahren zu ihrer herstellung und pharmazeutische mittel
IT1200422B (it) * 1985-03-19 1989-01-18 Ripari Gero Ist Farm Biolog Composto con attivita' antimicrobia,sua preparazione e composizioni farmaceutiche che lo contengono
ES2249992B1 (es) 2004-09-13 2007-03-01 Ferrer Internacional, S.A. Un procedimiento para fabricar compuestos enantiomericos del imidazol.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU557755A3 (ru) * 1968-08-19 1977-05-05 Янссен Фармасьютика Н.В. (Фирма) Способ получени производных имидазола
GB1475271A (en) * 1975-04-30 1977-06-01 Pfizer Ltd 1-aryl-2-1-imidazolyl-alkyl ethers and thioethers and their use as antifungal agents

Also Published As

Publication number Publication date
MX5927E (es) 1984-08-29
JPS605592B2 (ja) 1985-02-12
AR219596A1 (es) 1980-08-29
PH14782A (en) 1981-12-09
IE790958L (en) 1979-11-18
YU112279A (en) 1983-01-21
FR2426047A1 (fr) 1979-12-14
AU4714979A (en) 1979-11-22
NL7903872A (nl) 1979-11-20
SU816399A3 (ru) 1981-03-23
FI71309C (fi) 1986-12-19
IL57245A (en) 1983-02-23
NL930014I2 (nl) 1993-09-16
SE444812B (sv) 1986-05-12
DE2917244A1 (de) 1979-11-22
NZ190412A (en) 1981-03-16
FR2426047B1 (it) 1982-11-05
NL189255C (nl) 1993-02-16
FI791543A (fi) 1979-11-19
DK196579A (da) 1979-11-19
FI71309B (fi) 1986-09-09
ATA345079A (de) 1983-04-15
DK153838B (da) 1988-09-12
SE7904319L (sv) 1979-11-19
DK153838C (da) 1989-01-30
AU523053B2 (en) 1982-07-08
NO152840C (no) 1985-11-27
HU182565B (en) 1984-02-28
IE48372B1 (en) 1984-12-26
CH639075A5 (fr) 1983-10-31
NO791599L (no) 1979-11-20
IL57245A0 (en) 1979-09-30
GB2025395A (en) 1980-01-23
ES480552A1 (es) 1980-04-01
NO152840B (no) 1985-08-19
EG14345A (en) 1983-09-30
ZA792015B (en) 1980-04-30
PT69537A (fr) 1979-05-01
NL930014I1 (nl) 1993-05-03
DE2917244C2 (de) 1985-09-05
GB2025395B (en) 1982-07-28
DD143608A5 (de) 1980-09-03
GR68396B (it) 1981-12-29
CA1115718A (en) 1982-01-05
JPS54151974A (en) 1979-11-29
IT7823546A0 (it) 1978-05-18
AT372950B (de) 1983-11-25

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Legal Events

Date Code Title Description
ITCP Complementary protection certificate

Free format text: CCP 302

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 302, 19920513; RECORDATI INDUSTRIA CHIMICA E FARMA CEUTICA S.P.A.

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970129