[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

IL81611A - N-cycloalkano(1,2-b)indole derivatives of aryl-sulfonamides,their preparation and medicaments containing them - Google Patents

N-cycloalkano(1,2-b)indole derivatives of aryl-sulfonamides,their preparation and medicaments containing them

Info

Publication number
IL81611A
IL81611A IL81611A IL8161187A IL81611A IL 81611 A IL81611 A IL 81611A IL 81611 A IL81611 A IL 81611A IL 8161187 A IL8161187 A IL 8161187A IL 81611 A IL81611 A IL 81611A
Authority
IL
Israel
Prior art keywords
cycloalkano
sulfonamides
aryl
preparation
indole derivatives
Prior art date
Application number
IL81611A
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL81611A publication Critical patent/IL81611A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/86Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL81611A 1986-02-21 1987-02-18 N-cycloalkano(1,2-b)indole derivatives of aryl-sulfonamides,their preparation and medicaments containing them IL81611A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3605566 1986-02-21
DE19863631824 DE3631824A1 (de) 1986-02-21 1986-09-19 Cycloalkano(1.2-b)indol-sulfonamide

Publications (1)

Publication Number Publication Date
IL81611A true IL81611A (en) 1991-03-10

Family

ID=25841196

Family Applications (1)

Application Number Title Priority Date Filing Date
IL81611A IL81611A (en) 1986-02-21 1987-02-18 N-cycloalkano(1,2-b)indole derivatives of aryl-sulfonamides,their preparation and medicaments containing them

Country Status (19)

Country Link
US (3) US4827032A (fi)
EP (1) EP0242518B1 (fi)
JP (1) JPH075552B2 (fi)
KR (2) KR940007302B1 (fi)
AU (1) AU595855B2 (fi)
CA (1) CA1309414C (fi)
CS (1) CS275837B6 (fi)
DE (2) DE3631824A1 (fi)
DK (1) DK167009B1 (fi)
ES (1) ES2028801T3 (fi)
FI (1) FI86544C (fi)
GR (1) GR3001763T3 (fi)
HU (1) HU198686B (fi)
IE (1) IE59470B1 (fi)
IL (1) IL81611A (fi)
NO (1) NO171633C (fi)
NZ (1) NZ219319A (fi)
PH (1) PH24491A (fi)
PT (1) PT84316B (fi)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3826371A1 (de) * 1988-08-03 1990-02-08 Bayer Ag Tetrahydro-1-benz-(c,d)-indolpropionsaeure-sulfonamide
DE3829455A1 (de) * 1988-08-31 1990-03-15 Boehringer Mannheim Gmbh Sulfonamidoalkyl-cyclohexan-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel
US5006542A (en) * 1988-10-31 1991-04-09 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use
US4959383A (en) * 1988-10-31 1990-09-25 E. R. Squibb & Sons, Inc. Phenylsulfone alkenoic acids, derivatives thereof, compositions containing same and method of use
US5070099A (en) * 1988-10-31 1991-12-03 E. R. Squibb & Sons, Inc. Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same method of use
GB8924392D0 (en) * 1989-10-30 1989-12-20 Bayer Ag Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides
GB9008108D0 (en) * 1990-04-10 1990-06-06 Bayer Ag Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles
DE4027278A1 (de) * 1990-08-29 1992-03-05 Bayer Ag Heterocyclisch substituierte indolsulfonamide
US5827871A (en) * 1991-06-26 1998-10-27 Smithkline Beecham Plc Medicaments 1,2,3,4-tetrahydrocarbazoles and 5-HT1 agonist use thereof
DE4131346A1 (de) * 1991-09-20 1993-03-25 Bayer Ag Indolsulfonamid substituierte dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
ES2122982T3 (es) * 1992-12-18 1999-01-01 Smithkline Beecham Plc Derivados de tetrahidrocarbazol para la fabricacion de un medicamento para el tratamiento de una enfermedad en la que esta indicado un agonista similar a 5-ht1.
DE19507751A1 (de) * 1995-03-06 1996-09-12 Bayer Ag Verfahren zur Herstellung von substituierten 1,2,3,4-Tetrahydrocarbazolen
US5708187A (en) * 1996-06-27 1998-01-13 Eli Lilly And Company 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta 7,6-B!indoles: New 5-HT1F agonists
DE19757983A1 (de) 1997-12-24 1999-07-01 Bayer Yakuhin Ltd Thermodynamisch stabile Form von (r)-3[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazol-0-propansäure (Ramatroban)
CA2618550C (en) * 2005-08-12 2013-12-17 Merck Frosst Canada Ltd. Indole derivatives as crth2 receptor antagonists
US7662831B2 (en) * 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
US7601856B2 (en) * 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
KR101411820B1 (ko) 2006-08-07 2014-06-24 액테리온 파마슈티칼 리미티드 (3-아미노-1,2,3,4-테트라하이드로-9h-카르바졸-9-일)-아세트산 유도체
GB0624087D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril combination salt
GB0624090D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amine salts
GB0624084D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amino acid salts
CA2673214A1 (en) * 2006-12-20 2008-06-26 Cardoz Ab New combination for use in the treatment of inflammatory disorders
WO2008087371A1 (en) * 2007-01-16 2008-07-24 Cardoz Ab New combination for use in the treatment of inflammatory disorders
WO2009007674A2 (en) * 2007-07-11 2009-01-15 Cardoz Ab Combination for use in the treatment of atherosclerosis comprising a mast cell inhibitor and ramatroban or seratrodast
WO2010008864A2 (en) * 2008-06-24 2010-01-21 Amira Pharmaceuticals, Inc. Cycloalkane[b]indole angtagonists of prostaglandin d2 receptors
ES2378755T3 (es) * 2008-07-15 2012-04-17 F. Hoffmann-La Roche Ag �?cidos aminotetrahidroindazoloacéticos
ES2408963T3 (es) 2008-11-17 2013-06-24 F. Hoffmann-La Roche Ag Acidos naftilacéticos
EP2358677B1 (en) 2008-11-17 2014-01-08 F. Hoffmann-La Roche AG Naphthylacetic acids used as crth2 antagonists or partial agonists
CN102216249A (zh) 2008-11-17 2011-10-12 霍夫曼-拉罗奇有限公司 萘乙酸
MY183111A (en) 2010-03-22 2021-02-15 Idorsia Pharmaceuticals Ltd 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazole derivatives and their use as prostaglandin d2 receptor modulators
SG193902A1 (en) 2011-04-14 2013-11-29 Actelion Pharmaceuticals Ltd 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin d2 receptor modulators
US8470884B2 (en) 2011-11-09 2013-06-25 Hoffmann-La Roche Inc. Alkenyl naphthylacetic acids
SI3119779T1 (sl) 2014-03-17 2018-10-30 Idorsia Pharmaceuticals Ltd Derivati azaindolocetne kisline in njihova uporaba kot modulatorji prostaglandinskega receptorja D2
MX2016011900A (es) 2014-03-18 2016-12-05 Actelion Pharmaceuticals Ltd Derivados de acido azaindol-acetico y su uso como moduladores del receptor de prostaglandina d2.
WO2016128565A1 (en) 2015-02-13 2016-08-18 Institut National De La Sante Et De La Recherche Medicale (Inserm) Ptgdr-1 and/or ptgdr-2 antagonists for preventing and/or treating systemic lupus erythematosus
PL3350179T3 (pl) 2015-09-15 2021-08-02 Idorsia Pharmaceuticals Ltd Krystaliczne postacie

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1415322A (fr) * 1963-12-09 1965-10-22 Eastman Kodak Co Nouveaux composés de 3-sulfamidocyclobutanone et de 3-sulfamidocyclobutanol
US3642816A (en) * 1967-08-10 1972-02-15 Sterling Drug Inc 3-acetamido-1 2 3 4-tetrahydrocarbazole
JPS4713658Y1 (fi) * 1969-12-18 1972-05-18
CH586678A5 (fi) * 1970-05-25 1977-04-15 Hoffmann La Roche
DE2226702A1 (de) * 1972-05-25 1973-12-13 Schering Ag Neue mittel zur behandlung des diabetes mellitus
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
US4235901A (en) * 1978-05-08 1980-11-25 American Home Products Corporation 1-Hydroxyalkanamine pyrano(3,4-b)indole compositions and use thereof

Also Published As

Publication number Publication date
PH24491A (en) 1990-07-18
US4965258A (en) 1990-10-23
PT84316A (en) 1987-03-01
FI870693A0 (fi) 1987-02-19
CS275837B6 (en) 1992-03-18
PT84316B (pt) 1989-09-14
NO171633B (no) 1993-01-04
DK167009B1 (da) 1993-08-16
KR870007885A (ko) 1987-09-22
IE59470B1 (en) 1994-03-09
GR3001763T3 (en) 1992-11-23
DK87187A (da) 1987-08-22
DK87187D0 (da) 1987-02-20
FI86544C (fi) 1992-09-10
JPH0592954A (ja) 1993-04-16
CA1309414C (en) 1992-10-27
KR960001914B1 (en) 1996-02-06
CS8701093A2 (en) 1990-11-14
AU595855B2 (en) 1990-04-12
NO870437D0 (no) 1987-02-04
KR890001982A (ko) 1989-04-07
KR940007302B1 (ko) 1994-08-12
FI870693A (fi) 1987-08-22
NO870437L (no) 1987-08-24
DE3769191D1 (de) 1991-05-16
HU198686B (en) 1989-11-28
ES2028801T3 (es) 1992-07-16
US4904797A (en) 1990-02-27
HUT44493A (en) 1988-03-28
EP0242518B1 (de) 1991-04-10
JPH075552B2 (ja) 1995-01-25
NO171633C (no) 1993-04-14
AU6880887A (en) 1987-08-27
US4827032A (en) 1989-05-02
FI86544B (fi) 1992-05-29
EP0242518A1 (de) 1987-10-28
NZ219319A (en) 1990-12-21
IE870439L (en) 1987-08-21
DE3631824A1 (de) 1988-03-31

Similar Documents

Publication Publication Date Title
IL81611A (en) N-cycloalkano(1,2-b)indole derivatives of aryl-sulfonamides,their preparation and medicaments containing them
IL81201A (en) Indole derivatives,their preparation and pharmaceutical compositions containing them
IL86877A0 (en) Indole derivatives,their preparation and pharmaceutical compositions containing them
IL83198A (en) Benzenesulphonamidoindanyl derivatives,their preparation and medicaments containing them
NZ220345A (en) Imidazoquinolinylether derivatives and pharmaceutical compositions containing them
IL80411A0 (en) Preparation of dibenzopyranol derivatives and pharmaceutical compositions containing them
IL82246A0 (en) Quinoline derivatives,their preparation and pharmaceutical compositions containing them
IL79309A0 (en) (heterocyclic substituted-phenoxy)alkyl-isoxazoles and-furans,their preparation and pharmaceutical compositions containing them
GR3002636T3 (en) Pyrimidine derivatives, their preparation and medicaments containing these derivatives
IL86798A (en) 2,2-dimethylchroman-3-ol derivatives, their preparation and pharmaceutical compositions containing them
IL83432A (en) N-phenylcarboxamide derivatives,their preparation and pharmaceutical compositions containing them
NZ217580A (en) Tetrahydro-2-heterocyclyl alkyl-pyrido(4,3-b)indole derivatives and pharmaceutical compositions
IL82205A (en) Substituted alkane-sulfonamidophenyl derivatives and pharmaceutical compositions containing them
IL87089A (en) Derivatives of n-aminobutyl-n- phenylarylamides, their preparation and pharmaceutical compositions containing them
IL84098A0 (en) Tetrahydroquinoline derivatives,their preparation and pharmaceutical compositions containing them
IL84128A0 (en) 3-propenylcephem derivatives,their preparation and pharmaceutical compositions containing them
ZA871766B (en) Acetamide derivatives,their preparation and pharmaceutical compositions containing them
IL88002A0 (en) 2,2-dimethylchromene derivatives,their preparation and pharmaceutical compositions containing them
IL84636A0 (en) Lactam derivatives,their preparation and pharmaceutical compositions containing them
IL80658A0 (en) 6,7,8,9-tetrahydro-10-methyl-pyrido(1,2-a)indol-9-amines and derivatives thereof,their preparation and pharmaceutical compositions containing them
IL83412A0 (en) Pyrimidine derivatives,their preparation and medicaments containing them
IL83753A0 (en) Sulphonamidoethyl derivatives,their preparation and pharmaceutical compositions containing them
EP0256400A3 (en) Pyrimidine derivatives, their preparation and medicaments containing these derivatives
ZA879452B (en) 5-hydroxyethyl derivatives of oxazolidinone-2,their preparation and their therapeutic uses
IL92792A0 (en) Annelated indole derivatives,their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
KB Patent renewed
HC Change of name of proprietor(s)
KB Patent renewed
KB Patent renewed
EXP Patent expired