IL72417A - Amidine derivatives of 2-substituted 4-phenylimidazole,their preparation and pharmaceutical compositions containing them - Google Patents
Amidine derivatives of 2-substituted 4-phenylimidazole,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL72417A IL72417A IL72417A IL7241784A IL72417A IL 72417 A IL72417 A IL 72417A IL 72417 A IL72417 A IL 72417A IL 7241784 A IL7241784 A IL 7241784A IL 72417 A IL72417 A IL 72417A
- Authority
- IL
- Israel
- Prior art keywords
- group
- substituted
- alkyl
- phenylimidazole
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Treatment Of Sludge (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Processing Of Solid Wastes (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8322110A IT1206498B (it) | 1983-07-18 | 1983-07-18 | Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico. |
Publications (2)
Publication Number | Publication Date |
---|---|
IL72417A0 IL72417A0 (en) | 1984-11-30 |
IL72417A true IL72417A (en) | 1988-03-31 |
Family
ID=11191639
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL72417A IL72417A (en) | 1983-07-18 | 1984-07-16 | Amidine derivatives of 2-substituted 4-phenylimidazole,their preparation and pharmaceutical compositions containing them |
Country Status (28)
Country | Link |
---|---|
US (1) | US4649150A (it) |
EP (1) | EP0131973B1 (it) |
JP (1) | JPS6038367A (it) |
KR (1) | KR910000661B1 (it) |
AT (1) | ATE45149T1 (it) |
AU (1) | AU565292B2 (it) |
CA (1) | CA1257274A (it) |
CS (1) | CS244141B2 (it) |
DD (1) | DD232696A5 (it) |
DE (1) | DE3479212D1 (it) |
DK (1) | DK350084A (it) |
ES (2) | ES8601910A1 (it) |
FI (1) | FI842432A (it) |
GB (1) | GB2149395B (it) |
GR (1) | GR79981B (it) |
HK (1) | HK74287A (it) |
HU (1) | HU193292B (it) |
IL (1) | IL72417A (it) |
IT (1) | IT1206498B (it) |
NO (1) | NO162857C (it) |
NZ (1) | NZ208920A (it) |
PH (1) | PH21566A (it) |
PL (2) | PL143303B1 (it) |
PT (1) | PT78935B (it) |
SG (1) | SG48687G (it) |
SU (2) | SU1322979A3 (it) |
YU (2) | YU43367B (it) |
ZA (1) | ZA845490B (it) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4888348A (en) * | 1986-09-04 | 1989-12-19 | Ciba-Geigy Corporation | Substituted thioureas, isothioureas and carbodiimides |
US6121260A (en) | 1997-07-03 | 2000-09-19 | Neurogen Corporation | Method of treating conditions susceptible to modulation of NPY receptors with diarylimidazole derivatives |
US6887870B1 (en) | 1999-10-12 | 2005-05-03 | Bristol-Myers Squibb Company | Heterocyclic sodium/proton exchange inhibitors and method |
IL149872A0 (en) | 1999-12-16 | 2002-11-10 | Schering Corp | Substituted imidazole neuropeptide y y5 receptor antagonists |
FR2917087B1 (fr) | 2007-06-05 | 2012-09-21 | Galderma Res & Dev | Nouveaux 4-phenyl-imidazole-2-thiones comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique. |
EP4196793A1 (en) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1209431B (it) * | 1980-11-28 | 1989-07-16 | Angeli Inst Spa | Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione. |
-
1983
- 1983-07-18 IT IT8322110A patent/IT1206498B/it active
-
1984
- 1984-05-08 AT AT84200659T patent/ATE45149T1/de not_active IP Right Cessation
- 1984-05-08 EP EP84200659A patent/EP0131973B1/en not_active Expired
- 1984-05-08 DE DE8484200659T patent/DE3479212D1/de not_active Expired
- 1984-05-16 US US06/610,958 patent/US4649150A/en not_active Expired - Fee Related
- 1984-06-15 FI FI842432A patent/FI842432A/fi not_active Application Discontinuation
- 1984-07-02 YU YU1154/84A patent/YU43367B/xx unknown
- 1984-07-09 JP JP59142099A patent/JPS6038367A/ja active Pending
- 1984-07-11 PH PH30966A patent/PH21566A/en unknown
- 1984-07-16 PL PL1984248779A patent/PL143303B1/pl unknown
- 1984-07-16 DD DD84265319A patent/DD232696A5/de unknown
- 1984-07-16 KR KR1019840004177A patent/KR910000661B1/ko active IP Right Grant
- 1984-07-16 PL PL1984254625A patent/PL143732B1/pl unknown
- 1984-07-16 IL IL72417A patent/IL72417A/xx unknown
- 1984-07-17 CA CA000459030A patent/CA1257274A/en not_active Expired
- 1984-07-17 GB GB08418149A patent/GB2149395B/en not_active Expired
- 1984-07-17 ES ES534376A patent/ES8601910A1/es not_active Expired
- 1984-07-17 GR GR75327A patent/GR79981B/el unknown
- 1984-07-17 ZA ZA845490A patent/ZA845490B/xx unknown
- 1984-07-17 SU SU843770847A patent/SU1322979A3/ru active
- 1984-07-17 DK DK350084A patent/DK350084A/da not_active Application Discontinuation
- 1984-07-17 NO NO842921A patent/NO162857C/no unknown
- 1984-07-17 ES ES534375A patent/ES534375A0/es active Granted
- 1984-07-17 NZ NZ208920A patent/NZ208920A/en unknown
- 1984-07-17 HU HU842781A patent/HU193292B/hu not_active IP Right Cessation
- 1984-07-18 CS CS845542A patent/CS244141B2/cs unknown
- 1984-07-18 PT PT78935A patent/PT78935B/pt unknown
- 1984-07-18 AU AU30800/84A patent/AU565292B2/en not_active Ceased
-
1985
- 1985-01-29 SU SU853844125A patent/SU1313345A3/ru active
-
1986
- 1986-06-26 YU YU1126/86A patent/YU43701B/xx unknown
-
1987
- 1987-06-03 SG SG486/87A patent/SG48687G/en unknown
- 1987-10-15 HK HK742/87A patent/HK74287A/xx unknown
Also Published As
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DE3479212D1 (en) | New amidine derivatives of 2-substituted 4-phenilimidazole | |
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