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ES534376A0 - Un procedimiento para preparar nuevos derivados amidinicos de 4-fenilimidazol sustituido en la posicion 2 - Google Patents

Un procedimiento para preparar nuevos derivados amidinicos de 4-fenilimidazol sustituido en la posicion 2

Info

Publication number
ES534376A0
ES534376A0 ES534376A ES534376A ES534376A0 ES 534376 A0 ES534376 A0 ES 534376A0 ES 534376 A ES534376 A ES 534376A ES 534376 A ES534376 A ES 534376A ES 534376 A0 ES534376 A0 ES 534376A0
Authority
ES
Spain
Prior art keywords
group
substituted
alkyl
phenylimidazole
cyano
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES534376A
Other languages
English (en)
Other versions
ES8601910A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instituto de Angeli SpA
Original Assignee
Instituto de Angeli SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instituto de Angeli SpA filed Critical Instituto de Angeli SpA
Publication of ES534376A0 publication Critical patent/ES534376A0/es
Publication of ES8601910A1 publication Critical patent/ES8601910A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68Halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88Nitrogen atoms, e.g. allantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatment Of Sludge (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Processing Of Solid Wastes (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ES534376A 1983-07-18 1984-07-17 Un procedimiento para preparar nuevos derivados amidinicos de 4-fenilimidazol sustituido en la posicion 2 Expired ES8601910A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8322110A IT1206498B (it) 1983-07-18 1983-07-18 Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico.

Publications (2)

Publication Number Publication Date
ES534376A0 true ES534376A0 (es) 1985-11-01
ES8601910A1 ES8601910A1 (es) 1985-11-01

Family

ID=11191639

Family Applications (2)

Application Number Title Priority Date Filing Date
ES534376A Expired ES8601910A1 (es) 1983-07-18 1984-07-17 Un procedimiento para preparar nuevos derivados amidinicos de 4-fenilimidazol sustituido en la posicion 2
ES534375A Granted ES534375A0 (es) 1983-07-18 1984-07-17 Un procedimiento para preparar nuevos derivados amidinicos de 4-fenilimidazol sustituido en la posicion 2

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES534375A Granted ES534375A0 (es) 1983-07-18 1984-07-17 Un procedimiento para preparar nuevos derivados amidinicos de 4-fenilimidazol sustituido en la posicion 2

Country Status (28)

Country Link
US (1) US4649150A (es)
EP (1) EP0131973B1 (es)
JP (1) JPS6038367A (es)
KR (1) KR910000661B1 (es)
AT (1) ATE45149T1 (es)
AU (1) AU565292B2 (es)
CA (1) CA1257274A (es)
CS (1) CS244141B2 (es)
DD (1) DD232696A5 (es)
DE (1) DE3479212D1 (es)
DK (1) DK350084A (es)
ES (2) ES8601910A1 (es)
FI (1) FI842432A (es)
GB (1) GB2149395B (es)
GR (1) GR79981B (es)
HK (1) HK74287A (es)
HU (1) HU193292B (es)
IL (1) IL72417A (es)
IT (1) IT1206498B (es)
NO (1) NO162857C (es)
NZ (1) NZ208920A (es)
PH (1) PH21566A (es)
PL (2) PL143303B1 (es)
PT (1) PT78935B (es)
SG (1) SG48687G (es)
SU (2) SU1322979A3 (es)
YU (2) YU43367B (es)
ZA (1) ZA845490B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4888348A (en) * 1986-09-04 1989-12-19 Ciba-Geigy Corporation Substituted thioureas, isothioureas and carbodiimides
US6121260A (en) 1997-07-03 2000-09-19 Neurogen Corporation Method of treating conditions susceptible to modulation of NPY receptors with diarylimidazole derivatives
US6887870B1 (en) 1999-10-12 2005-05-03 Bristol-Myers Squibb Company Heterocyclic sodium/proton exchange inhibitors and method
IL149872A0 (en) 1999-12-16 2002-11-10 Schering Corp Substituted imidazole neuropeptide y y5 receptor antagonists
FR2917087B1 (fr) 2007-06-05 2012-09-21 Galderma Res & Dev Nouveaux 4-phenyl-imidazole-2-thiones comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique.
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209431B (it) * 1980-11-28 1989-07-16 Angeli Inst Spa Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione.

Also Published As

Publication number Publication date
PL248779A1 (en) 1985-12-03
ES8505962A1 (es) 1985-06-16
DK350084D0 (da) 1984-07-17
CA1257274A (en) 1989-07-11
YU115484A (en) 1986-12-31
GB2149395B (en) 1986-11-26
DK350084A (da) 1985-01-19
IT1206498B (it) 1989-04-27
HK74287A (en) 1987-10-23
NO162857B (no) 1989-11-20
NZ208920A (en) 1987-03-31
FI842432A0 (fi) 1984-06-15
PL143303B1 (en) 1988-02-29
NO162857C (no) 1990-02-28
SG48687G (en) 1987-07-24
DD232696A5 (de) 1986-02-05
YU43367B (en) 1989-06-30
YU112686A (en) 1987-12-31
JPS6038367A (ja) 1985-02-27
NO842921L (no) 1985-01-21
US4649150A (en) 1987-03-10
SU1322979A3 (ru) 1987-07-07
FI842432A (fi) 1985-01-19
EP0131973A1 (en) 1985-01-23
EP0131973B1 (en) 1989-08-02
IL72417A0 (en) 1984-11-30
CS244141B2 (en) 1986-07-17
ATE45149T1 (de) 1989-08-15
YU43701B (en) 1989-10-31
CS554284A2 (en) 1985-08-15
SU1313345A3 (ru) 1987-05-23
IL72417A (en) 1988-03-31
AU565292B2 (en) 1987-09-10
HU193292B (en) 1987-09-28
PL143732B1 (en) 1988-03-31
KR850001173A (ko) 1985-03-16
HUT34959A (en) 1985-05-28
GB2149395A (en) 1985-06-12
PL254625A1 (en) 1986-05-06
ZA845490B (en) 1986-03-26
DE3479212D1 (en) 1989-09-07
IT8322110A0 (it) 1983-07-18
PT78935A (de) 1984-08-01
ES8601910A1 (es) 1985-11-01
PH21566A (en) 1987-12-11
KR910000661B1 (ko) 1991-01-31
GR79981B (es) 1984-10-31
PT78935B (de) 1986-10-23
AU3080084A (en) 1985-01-24
GB8418149D0 (en) 1984-08-22
ES534375A0 (es) 1985-06-16

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