IL150310A0 - Substituted homopiperidinyl benzimidazole analogues as fundic relaxants - Google Patents

Substituted homopiperidinyl benzimidazole analogues as fundic relaxants

Info

Publication number: IL150310A0
Authority: IL; Israel
Prior art keywords: fundic; relaxants; benzimidazole analogues; substituted homopiperidinyl; substituted
Prior art date: 1999-12-21

Application number

IL15031000A

Other languages

English (en)

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-21

Filing date

2000-12-14

Publication date

2002-12-01

2000-12-14 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2002-12-01 Publication of IL150310A0 publication Critical patent/IL150310A0/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cosmetics (AREA)

IL15031000A 1999-12-21 2000-12-14 Substituted homopiperidinyl benzimidazole analogues as fundic relaxants IL150310A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP99204441		1999-12-21
PCT/EP2000/012858 WO2001046189A1 (en)	1999-12-21	2000-12-14	Substituted homopiperidinyl benzimidazole analogues as fundic relaxants

Publications (1)

Publication Number	Publication Date
IL150310A0 true IL150310A0 (en)	2002-12-01

Family

ID=8241040

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL15031000A IL150310A0 (en)	1999-12-21	2000-12-14	Substituted homopiperidinyl benzimidazole analogues as fundic relaxants
IL150310A IL150310A (en)	1999-12-21	2002-06-19	Analogs of homofipridinyl benzamidezol are converted as bottom Murphy

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL150310A IL150310A (en)	1999-12-21	2002-06-19	Analogs of homofipridinyl benzamidezol are converted as bottom Murphy

Country Status (33)

Country	Link
US (1)	US7304052B2 (et)
EP (1)	EP1250337B1 (et)
JP (1)	JP4852210B2 (et)
KR (1)	KR100715351B1 (et)
CN (1)	CN100343251C (et)
AT (1)	ATE416174T1 (et)
AU (1)	AU781144B2 (et)
BG (1)	BG65784B1 (et)
BR (1)	BRPI0016638B8 (et)
CA (1)	CA2393158C (et)
CY (1)	CY1108844T1 (et)
CZ (1)	CZ299803B6 (et)
DE (1)	DE60041001D1 (et)
DK (1)	DK1250337T3 (et)
EA (1)	EA005851B1 (et)
EE (1)	EE05182B1 (et)
ES (1)	ES2317856T3 (et)
HK (1)	HK1053109B (et)
HR (1)	HRP20020518B1 (et)
HU (1)	HU229929B1 (et)
IL (2)	IL150310A0 (et)
MX (1)	MXPA02006346A (et)
MY (1)	MY127758A (et)
NO (1)	NO322362B1 (et)
NZ (1)	NZ518816A (et)
PL (1)	PL199678B1 (et)
PT (1)	PT1250337E (et)
SI (1)	SI1250337T1 (et)
SK (1)	SK287113B6 (et)
TW (1)	TWI225488B (et)
UA (1)	UA73963C2 (et)
WO (1)	WO2001046189A1 (et)
ZA (1)	ZA200204983B (et)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI225488B (en)	1999-12-21	2004-12-21	Janssen Pharmaceutica Nv	Derivatives of homopiperidinyl substituted benzimidazole analogues
JO2352B1 (en) *	2000-06-22	2006-12-12	جانسين فارماسيوتيكا ان. في	Compounds for the treatment of non-adaptation of the bottom of the uterus
JP2005532991A (ja)	2002-01-10	2005-11-04	ニューロジェン・コーポレーション	メラニン凝集ホルモン受容体リガンド：置換２−（４−ベンジル−ピペラジン−１−イルメチル）−及び２−（４−ベンジル−ジアゼパン−１−イルメチル）−１ｈ−ベンゾイミダゾールアナログ
JPWO2005080348A1 (ja) *	2004-02-19	2007-08-02	萬有製薬株式会社	新規スルホンアミド誘導体
WO2008090200A2 (en) *	2007-01-25	2008-07-31	Janssen Pharmaceutica Nv	2- piperazin-1-yl-3h-imidazo[4,5-b]pyridine derivatives
HUE029174T2 (hu)	2010-06-24	2017-02-28	Gilead Sciences Inc	Pirazolo[1,5-A]pirimidinek és -triazinok mint antivirális szerek
WO2012070069A2 (en) *	2010-11-24	2012-05-31	Sequent Scientific Limited	A process for preparation of albendazole
JP2014159375A (ja) *	2011-06-15	2014-09-04	Takeda Chem Ind Ltd	アゼパン化合物
AU2012358805B2 (en)	2011-12-22	2017-07-20	Gilead Sciences, Inc.	Pyrazolo[1,5-a]pyrimidines as antiviral agents
CN104583211A (zh)	2012-04-17	2015-04-29	吉里德科学公司	用于抗病毒治疗的化合物和方法
WO2015091584A1 (en) *	2013-12-18	2015-06-25	F. Hoffmann-La Roche Ag	Thiazolopyridine compounds, compositions and their use as tyk2 kinase inhibitors

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2060197C3 (de)	1970-12-08	1979-02-22	Bayer Ag, 5090 Leverkusen	Verfahren zur Herstellung von 2-Aminobenzothiazol und dessen N-Alkylsubstitutionsprodukten
US4093726A (en)	1976-12-02	1978-06-06	Abbott Laboratories	N-(2-benzimidazolyl)-piperazines
ES482789A0 (es) *	1978-08-25	1980-12-01	Thomae Gmbh Dr K	Procedimiento para la preparacion de nuevos bencimidazoles sustituidos en posicion 5 o 6 con un anillo de piridazinona
JPS5879983A (ja) *	1981-11-06	1983-05-13	Kanebo Ltd	新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物
FR2528526A1 (fr) *	1982-06-09	1983-12-16	Sfr Sa Robinetterie	Butee se fixant dans un alesage d'un dispositif
DE3224512A1 (de) *	1982-07-01	1984-01-05	Dr. Karl Thomae Gmbh, 7950 Biberach	Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
PH23995A (en) *	1984-01-09	1990-02-09	Janssen Pharmaceutica Nv	4((bicycle heterocyclyl)-methyl and hetero)piperidines
DE3634066A1 (de) *	1986-10-07	1988-04-21	Boehringer Mannheim Gmbh	Neue 5-alkylbenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel
JPH0260197A (ja) *	1988-08-26	1990-02-28	Nec Corp	パッケージ構造
FR2674856B1 (fr) *	1991-04-05	1993-07-30	Esteve Labor Dr	Nouveaux antihistaminiques non sedatifs, derives de benzimidazole, leur procede de preparation et leur utilisation en tant que medicaments.
IL101851A (en) *	1991-06-13	1996-05-14	Janssen Pharmaceutica Nv	History 01 -) 4 - Pipridinyl - and Pipridinylidene (- Imidazo] A-1,2 [Pirolo, Thiano or Purano (] 3,2 [Azpin, their preparation and pharmaceutical preparations containing them and composition
DE4237656A1 (de) *	1992-06-13	1993-12-16	Merck Patent Gmbh	Benzimidazolderivate
RU95105442A (ru) *	1992-07-08	1997-02-20	Монсанто Компани (US)	Способ лечения язвы желудка у свиней, изделие для лечения язвы желудка у свиней
ES2048109B1 (es) *	1992-07-20	1994-12-16	Espanola Prod Quimicos	Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
ES2172585T3 (es) *	1994-05-31	2002-10-01	Mitsui Chemicals Inc	Derivado de benzoimidazol.
FR2766822B1 (fr) *	1997-07-30	2001-02-23	Adir	Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6150379A (en) *	1997-11-26	2000-11-21	Axys Pharmaceuticals, Inc.	Compounds and compositions as anticoagulants
TWI225488B (en)	1999-12-21	2004-12-21	Janssen Pharmaceutica Nv	Derivatives of homopiperidinyl substituted benzimidazole analogues

2000
- 2000-12-11 TW TW089126315A patent/TWI225488B/zh not_active IP Right Cessation
- 2000-12-14 CN CNB008174458A patent/CN100343251C/zh not_active Expired - Fee Related
- 2000-12-14 MX MXPA02006346A patent/MXPA02006346A/es active IP Right Grant
- 2000-12-14 DK DK00985180T patent/DK1250337T3/da active
- 2000-12-14 ES ES00985180T patent/ES2317856T3/es not_active Expired - Lifetime
- 2000-12-14 KR KR1020027006004A patent/KR100715351B1/ko not_active IP Right Cessation
- 2000-12-14 SK SK854-2002A patent/SK287113B6/sk not_active IP Right Cessation
- 2000-12-14 CZ CZ20022055A patent/CZ299803B6/cs not_active IP Right Cessation
- 2000-12-14 JP JP2001547099A patent/JP4852210B2/ja not_active Expired - Fee Related
- 2000-12-14 CA CA2393158A patent/CA2393158C/en not_active Expired - Fee Related
- 2000-12-14 PL PL355442A patent/PL199678B1/pl unknown
- 2000-12-14 US US10/169,011 patent/US7304052B2/en not_active Expired - Fee Related
- 2000-12-14 BR BRPI0016638A patent/BRPI0016638B8/pt not_active IP Right Cessation
- 2000-12-14 PT PT00985180T patent/PT1250337E/pt unknown
- 2000-12-14 AT AT00985180T patent/ATE416174T1/de active
- 2000-12-14 DE DE60041001T patent/DE60041001D1/de not_active Expired - Lifetime
- 2000-12-14 IL IL15031000A patent/IL150310A0/xx unknown
- 2000-12-14 AU AU21673/01A patent/AU781144B2/en not_active Ceased
- 2000-12-14 UA UA2002065092A patent/UA73963C2/uk unknown
- 2000-12-14 WO PCT/EP2000/012858 patent/WO2001046189A1/en active IP Right Grant
- 2000-12-14 NZ NZ518816A patent/NZ518816A/xx not_active IP Right Cessation
- 2000-12-14 EA EA200200700A patent/EA005851B1/ru not_active IP Right Cessation
- 2000-12-14 HU HU0203847A patent/HU229929B1/hu unknown
- 2000-12-14 EE EEP200200326A patent/EE05182B1/et not_active IP Right Cessation
- 2000-12-14 EP EP00985180A patent/EP1250337B1/en not_active Expired - Lifetime
- 2000-12-14 SI SI200031019T patent/SI1250337T1/sl unknown
- 2000-12-20 MY MYPI20006015A patent/MY127758A/en unknown
2002
- 2002-05-29 BG BG106749A patent/BG65784B1/bg unknown
- 2002-06-13 HR HR20020518A patent/HRP20020518B1/xx not_active IP Right Cessation
- 2002-06-19 IL IL150310A patent/IL150310A/en not_active IP Right Cessation
- 2002-06-20 NO NO20022977A patent/NO322362B1/no not_active IP Right Cessation
- 2002-06-20 ZA ZA200204983A patent/ZA200204983B/en unknown
2003
- 2003-07-23 HK HK03105325.2A patent/HK1053109B/zh not_active IP Right Cessation
2009
- 2009-03-03 CY CY20091100243T patent/CY1108844T1/el unknown

Also Published As

Publication number	Publication date
DK1250337T3 (da)	2009-03-30
ES2317856T3 (es)	2009-05-01
NO20022977L (no)	2002-08-08
SK8542002A3 (en)	2003-07-01
CA2393158C (en)	2010-10-19
MXPA02006346A (es)	2002-12-13
EP1250337A1 (en)	2002-10-23
CA2393158A1 (en)	2001-06-28
SK287113B6 (sk)	2009-12-07
DE60041001D1 (de)	2009-01-15
BRPI0016638B8 (pt)	2017-04-25
EA005851B1 (ru)	2005-06-30
HK1053109B (zh)	2008-08-01
JP4852210B2 (ja)	2012-01-11
HRP20020518A2 (en)	2004-08-31
AU781144B2 (en)	2005-05-05
BG65784B1 (bg)	2009-11-30
HUP0203847A2 (hu)	2003-03-28
JP2003518118A (ja)	2003-06-03
PL355442A1 (en)	2004-04-19
HK1053109A1 (en)	2003-10-10
ZA200204983B (en)	2003-09-22
NZ518816A (en)	2003-01-31
CY1108844T1 (el)	2014-07-02
CZ299803B6 (cs)	2008-12-03
CN1411460A (zh)	2003-04-16
HU229929B1 (en)	2015-01-28
SI1250337T1 (sl)	2009-04-30
MY127758A (en)	2006-12-29
US7304052B2 (en)	2007-12-04
PT1250337E (pt)	2009-03-05
BR0016638B1 (pt)	2013-02-05
KR100715351B1 (ko)	2007-05-08
NO322362B1 (no)	2006-09-25
US20030139393A1 (en)	2003-07-24
KR20020062643A (ko)	2002-07-26
HUP0203847A3 (en)	2004-07-28
HRP20020518B1 (en)	2009-02-28
IL150310A (en)	2008-07-08
BR0016638A (pt)	2002-10-01
NO20022977D0 (no)	2002-06-20
WO2001046189A1 (en)	2001-06-28
EA200200700A1 (ru)	2003-06-26
EE05182B1 (et)	2009-06-15
EP1250337B1 (en)	2008-12-03
AU2167301A (en)	2001-07-03
ATE416174T1 (de)	2008-12-15
TWI225488B (en)	2004-12-21
BG106749A (en)	2003-01-31
CN100343251C (zh)	2007-10-17
PL199678B1 (pl)	2008-10-31
EE200200326A (et)	2003-10-15
UA73963C2 (uk)	2005-10-17
CZ20022055A3 (cs)	2003-06-18

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IL150310A0 (en)	2002-12-01	Substituted homopiperidinyl benzimidazole analogues as fundic relaxants
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