[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

HK1010879A1 - Ipratropium bromide enantiomer with a prolonged duration of action - Google Patents

Ipratropium bromide enantiomer with a prolonged duration of action

Info

Publication number
HK1010879A1
HK1010879A1 HK98112141A HK98112141A HK1010879A1 HK 1010879 A1 HK1010879 A1 HK 1010879A1 HK 98112141 A HK98112141 A HK 98112141A HK 98112141 A HK98112141 A HK 98112141A HK 1010879 A1 HK1010879 A1 HK 1010879A1
Authority
HK
Hong Kong
Prior art keywords
action
ipratropium bromide
prolonged duration
enantiomer
bromide enantiomer
Prior art date
Application number
HK98112141A
Other languages
English (en)
Inventor
Rolf Banholzer
Richard Reichl
Bernd Disse
Georg Speck
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of HK1010879A1 publication Critical patent/HK1010879A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms
    • C07D451/10Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
HK98112141A 1995-08-01 1998-11-20 Ipratropium bromide enantiomer with a prolonged duration of action HK1010879A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19528145A DE19528145A1 (de) 1995-08-01 1995-08-01 Neue Arzneimittel und ihre Verwendung
PCT/EP1996/003364 WO1997005136A1 (de) 1995-08-01 1996-07-31 Ein enantiomer von ipratropiumbromid mit verlängerter wirkungsdauer

Publications (1)

Publication Number Publication Date
HK1010879A1 true HK1010879A1 (en) 1999-07-02

Family

ID=7768353

Family Applications (2)

Application Number Title Priority Date Filing Date
HK98111418A HK1013597A1 (en) 1995-08-01 1998-10-21 Preparations containing ipratropium bromide enantiomer with a prolonged duration of action
HK98112141A HK1010879A1 (en) 1995-08-01 1998-11-20 Ipratropium bromide enantiomer with a prolonged duration of action

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK98111418A HK1013597A1 (en) 1995-08-01 1998-10-21 Preparations containing ipratropium bromide enantiomer with a prolonged duration of action

Country Status (37)

Country Link
US (1) US6299861B1 (xx)
EP (1) EP0843676B1 (xx)
JP (1) JPH11510150A (xx)
KR (1) KR100445016B1 (xx)
CN (1) CN1120841C (xx)
AR (1) AR004179A1 (xx)
AT (1) ATE208390T1 (xx)
AU (1) AU6739796A (xx)
BG (1) BG63780B1 (xx)
BR (1) BR9609951A (xx)
CA (1) CA2226934C (xx)
CO (1) CO4750836A1 (xx)
CZ (1) CZ291998B6 (xx)
DE (2) DE19528145A1 (xx)
DK (1) DK0843676T3 (xx)
EE (1) EE04614B1 (xx)
ES (1) ES2167592T3 (xx)
HK (2) HK1013597A1 (xx)
HR (1) HRP960365B1 (xx)
HU (1) HU228056B1 (xx)
IL (1) IL118986A (xx)
MX (1) MX9800864A (xx)
MY (1) MY115201A (xx)
NO (1) NO317561B1 (xx)
NZ (1) NZ315645A (xx)
PL (1) PL183789B1 (xx)
PT (1) PT843676E (xx)
RO (1) RO120260B1 (xx)
RU (1) RU2171258C2 (xx)
SI (1) SI0843676T1 (xx)
SK (1) SK283260B6 (xx)
TR (1) TR199800121T1 (xx)
TW (1) TW449597B (xx)
UA (1) UA55391C2 (xx)
WO (1) WO1997005136A1 (xx)
YU (1) YU49479B (xx)
ZA (1) ZA966494B (xx)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19921693A1 (de) * 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
US20100197719A1 (en) * 1999-05-12 2010-08-05 Boehringer Ingelheim Pharma Kg Medicament compositions containing anticholinergically-effective compounds and betamimetics
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US6858593B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
US6777400B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6787532B2 (en) 2000-08-05 2004-09-07 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivatives
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
US6750210B2 (en) 2000-08-05 2004-06-15 Smithkline Beecham Corporation Formulation containing novel anti-inflammatory androstane derivative
US20020151541A1 (en) * 2000-10-31 2002-10-17 Michel Pairet Pharmaceutical compositions containing tiotropium salts and antihistamines and their use
US7776315B2 (en) * 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
US20100310477A1 (en) * 2000-11-28 2010-12-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg. Pharmaceutical compositions based on anticholingerics and additional active ingredients
UA77656C2 (en) 2001-04-07 2007-01-15 Glaxo Group Ltd S-fluoromethyl ester of 6-alpha, 9-alpha-difluoro-17-alpha-[(2-furanylcarbonyl)oxy]-11-beta-hydroxy-16- alpha-methyl-3-oxoandrosta-1,4-dien-17-beta-carbothioacid as anti-inflammatory agent
US6455028B1 (en) * 2001-04-23 2002-09-24 Pharmascience Ipratropium formulation for pulmonary inhalation
US20050070487A1 (en) * 2001-04-24 2005-03-31 Nyce Jonathan W. Composition, formulations and kit for treatment of respiratory and lung disease with non-glucocorticoid steroids and/or ubiquinone and a bronchodilating agent
US20030018019A1 (en) * 2001-06-23 2003-01-23 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US20050043343A1 (en) * 2003-07-28 2005-02-24 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a PDE IV inhibitor
US20050026948A1 (en) * 2003-07-29 2005-02-03 Boehringer Ingelheim International Gmbh Medicaments for inhalation comprising an anticholinergic and a betamimetic
US20050038004A1 (en) * 2003-07-31 2005-02-17 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anticholinergic bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20050101545A1 (en) * 2003-07-31 2005-05-12 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an anticholinergic bronchodilator for treatment of asthma or chronic obstructive pulmonary disease
US20090317476A1 (en) * 2003-07-31 2009-12-24 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20050026882A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
ES2257152B1 (es) * 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
PE20060826A1 (es) * 2004-12-06 2006-10-08 Smithkline Beecham Corp Derivado oleofinico de 8-azoniabiciclo[3.2.1]octano y combinacion farmaceutica que lo comprende
US20060239935A1 (en) * 2005-04-23 2006-10-26 Boehringer Ingelheim International Gmbh Compositions for inhalation
EP1879571A1 (de) * 2005-04-23 2008-01-23 Boehringer Ingelheim International GmbH Arzneimittelkombination für die inhalation enthaltend neben einem anticholinergikum ein betamimetikum und ein steroid
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
TW201311649A (zh) * 2011-09-05 2013-03-16 Everlight Chem Ind Corp 用於太陽能電池電解液之化合物及其製法、含有該化合物之電解液及太陽能電池
CN111751454B (zh) * 2019-03-29 2023-12-08 天津药业研究院股份有限公司 一种异丙托溴铵中间体i的含量和有关物质的检测方法
CN110361494B (zh) * 2019-06-26 2023-08-15 四川普锐特药业有限公司 异丙托溴铵气雾剂中杂质g的检测方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3505337A (en) * 1967-12-22 1970-04-07 Boehringer Sohn Ingelheim N - hydrocarbyl-substituted noratropinium,haloalkylates and o-acyl derivatives thereof
DE2903957A1 (de) * 1979-02-02 1980-08-07 Boehringer Sohn Ingelheim Mittel zur behandlung der nasalen hypersekretion
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
DE4140861C2 (de) * 1991-12-11 2003-12-11 Boehringer Ingelheim Kg Verfahren zur Gewinnung von quartären Tropasäurealkaloiden
DE69324161T2 (de) * 1992-12-09 1999-10-28 Boehringer Ingelheim Pharmaceuticals Inc., Ridgefield Stabilisierte medizinische aerosollösungen

Also Published As

Publication number Publication date
CA2226934C (en) 2007-05-01
NO980424L (no) 1998-01-30
SK11298A3 (en) 1998-07-08
ES2167592T3 (es) 2002-05-16
CZ225396A3 (cs) 1998-03-18
MX9800864A (es) 1998-04-30
MY115201A (en) 2003-04-30
HK1013597A1 (en) 1999-09-03
ZA966494B (en) 1997-02-03
HUP9602104A3 (en) 2000-03-28
RU2171258C2 (ru) 2001-07-27
WO1997005136A1 (de) 1997-02-13
NO317561B1 (no) 2004-11-15
NZ315645A (en) 1999-11-29
KR19990035997A (ko) 1999-05-25
CZ291998B6 (cs) 2003-07-16
TR199800121T1 (xx) 1998-04-21
HRP960365A2 (en) 1998-02-28
EE04614B1 (et) 2006-04-17
HRP960365B1 (en) 2002-04-30
CN1191535A (zh) 1998-08-26
YU49479B (sh) 2006-05-25
CN1120841C (zh) 2003-09-10
HUP9602104A2 (en) 1997-04-28
IL118986A0 (en) 1996-10-31
SI0843676T1 (en) 2002-06-30
AU6739796A (en) 1997-02-26
US6299861B1 (en) 2001-10-09
EP0843676A1 (de) 1998-05-27
PL183789B1 (pl) 2002-07-31
PL324804A1 (en) 1998-06-22
DK0843676T3 (da) 2001-12-27
KR100445016B1 (ko) 2004-11-08
SK283260B6 (sk) 2003-04-01
NO980424D0 (no) 1998-01-30
BG63780B1 (bg) 2002-12-29
UA55391C2 (uk) 2003-04-15
BG102202A (en) 1998-09-30
EE9800028A (et) 1998-08-17
CA2226934A1 (en) 1997-02-13
BR9609951A (pt) 1999-02-02
DE19528145A1 (de) 1997-02-06
AR004179A1 (es) 1998-11-04
EP0843676B1 (de) 2001-11-07
DE59608156D1 (de) 2001-12-13
PT843676E (pt) 2002-04-29
IL118986A (en) 1998-12-06
RO120260B1 (ro) 2005-11-30
TW449597B (en) 2001-08-11
HU228056B1 (en) 2012-09-28
JPH11510150A (ja) 1999-09-07
YU44596A (sh) 1998-12-23
ATE208390T1 (de) 2001-11-15
CO4750836A1 (es) 1999-03-31
HU9602104D0 (en) 1996-09-30

Similar Documents

Publication Publication Date Title
HK1010879A1 (en) Ipratropium bromide enantiomer with a prolonged duration of action
AU128429S (en) A toothbrush
GB2292309B (en) A brush rest
ZA962982B (en) A new combination
GB9610653D0 (en) A toothbrush
PL323721A1 (en) Needle of lauching home a needle
AU130002S (en) A toothbrush
GB2302846B (en) Bicycle hub
GB2301014B (en) A reservoir
AU127076S (en) A pot
AU130643S (en) A toothbrush
AU130105S (en) A toothbrush
GB2299750B (en) A toothbrush
GB2325712B (en) A hub of a bicycle
GB9601795D0 (en) A coaster
GB9519001D0 (en) Hub cap clocks
AU125856S (en) A pot
AU125074S (en) A pot
AU125611S (en) A pot
AU130001S (en) A toothbrush
AU127365S (en) A cap
CA76026S (en) Deep pot
AU126314S (en) A decorative fence cap
AU129138S (en) A bracket
GB9511299D0 (en) A bracket

Legal Events

Date Code Title Description
PF Patent in force