|
DE3413608A1
(de)
*
|
1984-04-11 |
1985-10-24 |
Hoechst Ag, 6230 Frankfurt |
Implantierbare zubereitungen von regulatorischen peptiden mit gesteuerter freisetzung und verfahren zu ihrer herstellung
|
|
IL79134A
(en)
*
|
1985-07-29 |
1991-06-10 |
American Cyanamid Co |
Continuous release peptide implants for parenteral administration
|
|
US5137874A
(en)
*
|
1985-07-29 |
1992-08-11 |
American Cyanamid Co. |
Partially coated C10 -C20 fatty acid salts of peptides having molecular weights up to about 5,000
|
|
US4761289A
(en)
*
|
1986-10-10 |
1988-08-02 |
International Minerals & Chemical Corp. |
Sustained release implant and method for preparing same
|
|
ATE151638T1
(de)
|
1987-02-20 |
1997-05-15 |
Genentech Inc |
Verfahren und zubereitungen für die verwendung von hiv-env-polypeptiden und antikörpern
|
|
DE3712095A1
(de)
*
|
1987-04-10 |
1988-10-20 |
Lentia Gmbh |
Bindemittelfreies granulat mit verzoegerter wirkstoffabgabe
|
|
DE3811231A1
(de)
*
|
1988-04-02 |
1989-10-12 |
Beiersdorf Ag |
Chirurgische implantate
|
|
DE59003337D1
(de)
*
|
1989-10-16 |
1993-12-09 |
Danubia Petrochem Polymere |
Pressling mit retardierter Wirkstofffreisetzung.
|
|
US5470582A
(en)
*
|
1992-02-07 |
1995-11-28 |
Syntex (U.S.A.) Inc. |
Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
|
|
JP2651320B2
(ja)
*
|
1992-07-16 |
1997-09-10 |
田辺製薬株式会社 |
徐放性マイクロスフェア製剤の製造方法
|
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
|
DE4423131A1
(de)
*
|
1994-07-01 |
1996-01-04 |
Bayer Ag |
Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4
|
|
US6093697A
(en)
*
|
1994-11-07 |
2000-07-25 |
The University Of Virginia Patent Foundation |
Synthetic insulin mimetic substances
|
|
US5599535A
(en)
*
|
1995-06-07 |
1997-02-04 |
Regents Of The University Of California |
Methods for the cyto-protection of the trabecular meshwork
|
|
US5674888A
(en)
*
|
1995-06-07 |
1997-10-07 |
University Of California |
Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
|
|
US7005505B1
(en)
|
1995-08-25 |
2006-02-28 |
Genentech, Inc. |
Variants of vascular endothelial cell growth factor
|
|
US6020473A
(en)
*
|
1995-08-25 |
2000-02-01 |
Genentech, Inc. |
Nucleic acids encoding variants of vascular endothelial cell growth factor
|
|
US7888466B2
(en)
|
1996-01-11 |
2011-02-15 |
Human Genome Sciences, Inc. |
Human G-protein chemokine receptor HSATU68
|
|
ZA978334B
(en)
*
|
1996-09-16 |
1999-03-16 |
Univ Dalhousie |
Use of IFG-I for the treatment of kidney disorders renal insufficiencies steriod toxicity and related indications
|
|
ATE302272T1
(de)
|
1996-10-25 |
2005-09-15 |
Human Genome Sciences Inc |
Neutrokin alpha
|
|
US7390891B1
(en)
|
1996-11-15 |
2008-06-24 |
Amgen Inc. |
Polynucleotides encoding a telomerase component TP2
|
|
WO1998054206A1
(en)
|
1997-05-30 |
1998-12-03 |
Human Genome Sciences, Inc. |
32 human secreted proteins
|
|
WO1999047677A2
(en)
|
1998-03-17 |
1999-09-23 |
Genentech, Inc. |
Polypeptides homologous to vegf and bmp1
|
|
US6342220B1
(en)
|
1997-08-25 |
2002-01-29 |
Genentech, Inc. |
Agonist antibodies
|
|
ATE442385T1
(de)
|
1997-09-17 |
2009-09-15 |
Human Genome Sciences Inc |
Interleukin-17 rezeptor-ähnliches protein
|
|
US5906979A
(en)
*
|
1998-01-27 |
1999-05-25 |
Insmed Pharmaceuticals, Inc. |
Compositions and methods for treating metabolic diseases characterized by hyperandrogenism and/or anovulation and/or infertility
|
|
EP2050762A3
(en)
|
1998-03-10 |
2009-07-08 |
Genentech, Inc. |
Human cornichon-like protein and nucleic acids encoding it
|
|
ATE490980T1
(de)
|
1998-03-19 |
2010-12-15 |
Human Genome Sciences |
Der gemeinsamen gamma-kette ähnlicher zytokinrezeptor
|
|
US5973119A
(en)
*
|
1998-06-05 |
1999-10-26 |
Amgen Inc. |
Cyclin E genes and proteins
|
|
US6344541B1
(en)
|
1998-09-25 |
2002-02-05 |
Amgen Inc. |
DKR polypeptides
|
|
AUPP785098A0
(en)
|
1998-12-21 |
1999-01-21 |
Victor Chang Cardiac Research Institute, The |
Treatment of heart disease
|
|
US6303749B1
(en)
|
1999-01-29 |
2001-10-16 |
Amgen Inc. |
Agouti and agouti-related peptide analogs
|
|
US8624010B1
(en)
|
1999-02-03 |
2014-01-07 |
Steven K. Yoshinaga |
Nucleic acids encoding B7RP1
|
|
US7435796B1
(en)
|
1999-02-03 |
2008-10-14 |
Amgen Inc. |
Antibodies which bind B7RP1
|
|
DK2332978T3
(da)
|
1999-02-03 |
2014-06-23 |
Amgen Inc |
Nye polypeptider, der er involveret ved et immunrespons
|
|
US7708993B2
(en)
|
1999-02-03 |
2010-05-04 |
Amgen Inc. |
Polypeptides involved in immune response
|
|
AU3501700A
(en)
|
1999-02-26 |
2000-09-14 |
Human Genome Sciences, Inc. |
Human endokine alpha and methods of use
|
|
WO2000058479A1
(en)
|
1999-03-26 |
2000-10-05 |
Amgen Inc. |
Beta secretase genes and polypeptides
|
|
US6635249B1
(en)
|
1999-04-23 |
2003-10-21 |
Cenes Pharmaceuticals, Inc. |
Methods for treating congestive heart failure
|
|
KR100674528B1
(ko)
|
1999-06-28 |
2007-01-29 |
제넨테크, 인크. |
2가 금속 이온을 사용한 Ａｐｏ-2 리간드 제조 방법
|
|
US7408047B1
(en)
|
1999-09-07 |
2008-08-05 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
US7459540B1
(en)
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
US7514239B2
(en)
|
2000-03-28 |
2009-04-07 |
Amgen Inc. |
Nucleic acid molecules encoding beta-like glycoprotein hormone polypeptides and heterodimers thereof
|
|
EP2267026A1
(en)
|
2000-04-12 |
2010-12-29 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
CA2413160A1
(en)
|
2000-06-15 |
2001-12-20 |
Human Genome Sciences, Inc. |
Human tumor necrosis factor delta and epsilon
|
|
CA2709771A1
(en)
|
2000-06-23 |
2002-01-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
EP2792747A1
(en)
|
2000-06-23 |
2014-10-22 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
ATE419351T1
(de)
|
2000-06-28 |
2009-01-15 |
Amgen Inc |
Thymus-stroma lymphopoietin rezeptor-moleküle und deren verwendung
|
|
US6989247B2
(en)
|
2000-11-28 |
2006-01-24 |
Celltech R & D, Inc. |
Compositions and methods for diagnosing or treating psoriasis
|
|
EP2351840A1
(en)
|
2000-11-28 |
2011-08-03 |
Amgen Inc. |
Polypeptides involved in immune response
|
|
US7087726B2
(en)
|
2001-02-22 |
2006-08-08 |
Genentech, Inc. |
Anti-interferon-α antibodies
|
|
AUPR546801A0
(en)
|
2001-06-05 |
2001-06-28 |
Commonwealth Scientific And Industrial Research Organisation |
Recombinant antibodies
|
|
DE60235989D1
(de)
|
2001-06-26 |
2010-05-27 |
Amgen Fremont Inc |
Antikörper gegen opgl
|
|
EP1572887A4
(en)
|
2001-08-24 |
2008-12-24 |
Neuren Pharmaceuticals Ltd |
NEURAL REGENERATION PEPTIDES AND METHODS OF USE THEREOF IN THE TREATMENT OF CEREBRAL LESIONS
|
|
ATE557092T1
(de)
|
2001-08-29 |
2012-05-15 |
Genentech Inc |
Bv8-nukleinsäuren und polypeptide mit mitogener aktivität
|
|
MXPA04002751A
(es)
|
2001-09-24 |
2005-09-08 |
Univ Oregon Health & Science |
Modificacion del comportamiento de alimentacion.
|
|
WO2003029420A2
(en)
|
2001-10-02 |
2003-04-10 |
Genentech, Inc. |
Apo-2 ligand variants and uses thereof
|
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
ATE423571T1
(de)
|
2001-10-12 |
2009-03-15 |
Schering Corp |
Verwendung von bispezifischen antikörpern gegen einen aktivierenden rezeptor fcepsilonri und gegen einen inhibierenden rezeptor ox2ra (cd200ra) zur regulierung der immunantworten
|
|
CA2466054C
(en)
|
2001-11-13 |
2012-01-03 |
Genentech, Inc. |
Apo-2 ligand/trail formulations
|
|
ES2500918T3
(es)
|
2001-12-21 |
2014-10-01 |
Human Genome Sciences, Inc. |
Proteínas de fusión de albúmina e interferón beta
|
|
US8058233B2
(en)
|
2002-01-10 |
2011-11-15 |
Oregon Health And Science University |
Modification of feeding behavior using PYY and GLP-1
|
|
WO2003057235A2
(en)
|
2002-01-10 |
2003-07-17 |
Imperial College Innovations Ltd |
Modification of feeding behavior
|
|
US7662924B2
(en)
|
2002-02-22 |
2010-02-16 |
The Board Of Trustees Of The University Of Illinois |
Beta chain-associated regulator of apoptosis
|
|
EP2314316A1
(en)
|
2002-04-05 |
2011-04-27 |
Amgen, Inc |
Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
|
|
EP1500665B1
(en)
|
2002-04-15 |
2011-06-15 |
Chugai Seiyaku Kabushiki Kaisha |
METHODS FOR CONSTRUCTING scDb LIBRARIES
|
|
EP1505148B1
(en)
|
2002-04-26 |
2009-04-15 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of screening for agonistic antibodies
|
|
WO2003099320A1
(en)
|
2002-05-24 |
2003-12-04 |
Zensun (Shanghai) Sci-Tech.Ltd |
Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
|
|
EP2305710A3
(en)
|
2002-06-03 |
2013-05-29 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
EP1556076A4
(en)
|
2002-06-24 |
2009-07-08 |
Genentech Inc |
APO-2 LIGAND / TRAIL VARIANTS AND ITS USES
|
|
ES2565189T3
(es)
|
2002-09-06 |
2016-04-01 |
Amgen, Inc |
Anticuerpo monoclonal anti-IL-1R1 humano terapéutico
|
|
US9809654B2
(en)
|
2002-09-27 |
2017-11-07 |
Vaccinex, Inc. |
Targeted CD1d molecules
|
|
US7335743B2
(en)
|
2002-10-16 |
2008-02-26 |
Amgen Inc. |
Human anti-IFN-γ neutralizing antibodies as selective IFN-γ pathway inhibitors
|
|
US7285269B2
(en)
|
2002-12-02 |
2007-10-23 |
Amgen Fremont, Inc. |
Antibodies directed to tumor necrosis factor
|
|
MXPA05007019A
(es)
|
2002-12-30 |
2005-08-18 |
Amgen Inc |
Terapia de combinacion con factores co-estimuladores.
|
|
GB0300571D0
(en)
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
AU2004207536B2
(en)
|
2003-01-24 |
2010-05-20 |
Elan Pharmaceuticals Inc. |
Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents
|
|
CN102225194B
(zh)
|
2003-03-12 |
2014-07-16 |
健泰科生物技术公司 |
Bv8和/或EG-VEGF促进造血的用途
|
|
JP2007525434A
(ja)
|
2003-03-19 |
2007-09-06 |
アブジェニックス インコーポレイテッド |
Ｔ細胞、免疫グロブリンドメインおよびムチンドメイン１（ｔｉｍ−１）抗原に対する抗体およびその使用。
|
|
US7375076B2
(en)
|
2003-05-20 |
2008-05-20 |
The Regents Of The University Of Michigan |
Methods of reducing vascular permeability in tissue by inhibition of tissue plasminogen activator (tPA) and tPA inhibitors useful therein
|
|
AU2004260936B2
(en)
|
2003-06-27 |
2010-06-10 |
Amgen Fremont Inc. |
Antibodies directed to the deletion mutants of epidermal growth factor receptor and uses thereof
|
|
SI1648998T1
(sl)
|
2003-07-18 |
2015-01-30 |
Amgen Inc. |
Specifiäťna vezavna sredstva na hepatocitni rastni faktor
|
|
HUE027218T2
(en)
|
2003-09-12 |
2016-10-28 |
Ipsen Biopharmaceuticals Inc |
Methods for Treatment of IGF-1 (Insulin-like Growth Factor 1) Deficiency
|
|
AU2003271174A1
(en)
|
2003-10-10 |
2005-04-27 |
Chugai Seiyaku Kabushiki Kaisha |
Double specific antibodies substituting for functional protein
|
|
EP1693448A4
(en)
|
2003-10-14 |
2008-03-05 |
Chugai Pharmaceutical Co Ltd |
DOUBLE SPECIFICITY ANTIBODY FOR FUNCTIONAL PROTEIN SUBSTITUTION
|
|
WO2005044188A2
(en)
|
2003-10-27 |
2005-05-19 |
Amgen Inc. |
Compositions and methods to modulate an immune response to an immunogenic therapeutic agent
|
|
WO2006069220A2
(en)
|
2004-12-22 |
2006-06-29 |
Ambrx, Inc. |
Modified human growth hormone
|
|
US8778880B2
(en)
|
2004-02-02 |
2014-07-15 |
Ambrx, Inc. |
Human growth hormone modified at position 35
|
|
BRPI0507451A
(pt)
|
2004-02-06 |
2007-07-10 |
Elan Pharm Inc |
método e terapia combinada para inibir o crescimento de tumor e/ou progressão metastática e/ou desenvolvimento de metástases, e, uso de uma imunoglobulina anti-alfa4 integrina
|
|
EP1726647B1
(en)
|
2004-03-19 |
2015-01-07 |
GenomIdea, Inc. |
Gene promoting vascular endothelial cell growth
|
|
EP1729804A2
(en)
|
2004-03-19 |
2006-12-13 |
Amgen Inc. |
Reducing the risk of human and anti-human antibodies through v gene manipulation
|
|
MY162179A
(en)
|
2004-04-01 |
2017-05-31 |
Elan Pharm Inc |
Steroid sparing agents and methods of using same
|
|
EP1598428A1
(en)
|
2004-05-18 |
2005-11-23 |
Georg Dewald |
Methods and kits to detect Hereditary angioedema type III
|
|
ES2777924T3
(es)
|
2004-05-23 |
2020-08-06 |
Hmi Medical Innovations Llc |
Moduladores de teramuteína
|
|
EP2298335B1
(en)
|
2004-05-25 |
2014-09-03 |
Stryker Corporation |
Use of OP-1 for treating cartilage defects
|
|
BRPI0512235A
(pt)
|
2004-06-18 |
2008-02-19 |
Ambrx Inc |
polipeptìdeos ligadores de antìgenos e seus usos
|
|
EP1758999B1
(en)
|
2004-06-22 |
2011-03-09 |
The Board Of Trustees Of The University Of Illinois |
METHODS OF INHIBITING TUMOR CELL PROLIFERATION WITH FOXM1 siRNA
|
|
PT1776136E
(pt)
|
2004-06-24 |
2012-12-05 |
Biogen Idec Inc |
Tratamento de estados que envolvem desmielinização
|
|
ME00226B
(me)
|
2004-07-15 |
2011-02-10 |
Medarex Llc |
Humana anti-ngf neutrališuća antitijela kao selektivni inhibitori ngf signalne kaskade
|
|
CA2576193A1
(en)
|
2004-08-03 |
2006-02-16 |
Biogen Idec Ma Inc. |
Taj in neuronal function
|
|
JP4840939B2
(ja)
|
2004-08-04 |
2011-12-21 |
アムジェン インコーポレイテッド |
Ｄｋｋ−１に対する抗体
|
|
AU2005277384B2
(en)
|
2004-08-17 |
2011-11-17 |
The Johns Hopkins University |
PDE5 inhibitor compositions and methods for treating cardiac indications
|
|
CN101072580B
(zh)
|
2004-10-06 |
2012-08-22 |
农业生物技术有限公司 |
抗体制备方法
|
|
WO2006041048A1
(ja)
|
2004-10-15 |
2006-04-20 |
Mie University |
肝再生・修復制御剤
|
|
AU2005307831A1
(en)
|
2004-11-17 |
2006-05-26 |
Amgen, Inc. |
Fully human monoclonal antibodies to IL-13
|
|
EP1827446A4
(en)
|
2004-12-06 |
2011-01-12 |
Siga Technologies Inc |
SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND URETINS, PHARMACEUTICAL COMPOSITIONS THEREOF AND METHOD FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS WITH ARENA VIRUSES
|
|
AU2005319404B2
(en)
|
2004-12-20 |
2011-10-20 |
Amgen Fremont Inc. |
Binding proteins specific for human Matriptase
|
|
CN101128483B
(zh)
|
2004-12-21 |
2015-06-03 |
阿斯利康公司 |
血管生成素-2的抗体及其应用
|
|
NZ555308A
(en)
|
2004-12-22 |
2010-10-29 |
Ambrx Inc |
Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
|
|
WO2006081139A2
(en)
|
2005-01-26 |
2006-08-03 |
Abgenix, Inc. |
Antibodies against interleukin-1 beta
|
|
EP2824183B1
(en)
|
2005-04-08 |
2020-07-29 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for producing bispecific antibodies
|
|
US20080009546A1
(en)
|
2005-05-06 |
2008-01-10 |
Chevron U.S.A. Inc. |
Diamondoid derivatives possessing therapeutic activity in the treatment of neurologic disorders
|
|
JP2008540571A
(ja)
|
2005-05-12 |
2008-11-20 |
ウィスコンシン・アルムニ・リサーチ・ファウンデーション |
Ｐｉｎ１の遮断は活性化した免疫細胞によるサイトカイン産生を防ぐ
|
|
US8431110B2
(en)
|
2005-05-23 |
2013-04-30 |
Hmi Medical Innovations, Llc. |
Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
|
|
WO2006132363A1
(ja)
|
2005-06-10 |
2006-12-14 |
Chugai Seiyaku Kabushiki Kaisha |
メグルミンを含有するタンパク質製剤の安定化剤、およびその利用
|
|
JP5224580B2
(ja)
|
2005-06-10 |
2013-07-03 |
中外製薬株式会社 |
ｓｃ（Ｆｖ）２部位特異的変異体
|
|
WO2006138181A2
(en)
|
2005-06-14 |
2006-12-28 |
Amgen Inc. |
Self-buffering protein formulations
|
|
BRPI0612273C1
(pt)
|
2005-06-21 |
2021-05-25 |
Xoma Us Llc |
anticorpo de ligação a il-1 beta ou fragmento de ligação a il-1 beta do mesmo, ácido nucleico, vetor, e, composição
|
|
EP1904104B1
(en)
|
2005-07-08 |
2013-09-11 |
Biogen Idec MA Inc. |
Sp35 antibodies and uses thereof
|
|
EP2388276A3
(en)
|
2005-07-18 |
2013-11-27 |
Amgen, Inc |
Human anti-B7RP1 neutralizing antibodies
|
|
BRPI0615962A2
(pt)
|
2005-07-27 |
2011-05-31 |
Univ Florida |
uso de um composto selecionado do grupo que consiste em um inibidor proteassomal, um inibidor de autofagia, um inibidor lisossomal, um inibidor do trasporte de proteìna do er ao golgi, um inibidor de chaperonina hsp90, um ativador da resposta a choque térmico, um inibidor de glicosidade, e um inibidor de histona deacetilase, uso de 11-cis-retinal ou 9-cis-retinal e um composto selecionado do grupo que consiste em um inibidor proteassomal, um inibidor de autofagia, um inibidor lissosomal, um inibidor do transporte de proteìna do er ao golgi, um inibidor de chaperonina hsp90, um ativador de resposta a choque térmico, um inibidor de glicosidase, e um inibidor de histona deacetilase, método para aumentar a quantidade de um conformação bioquimicamente funcional de uma proteìna em uma célula, composição farmacêutica para o tratamento de um pcd ocular, composição farmacêutica para o tratamento de retinite pigmentosa, kit para o tratamento de um pcd ocular, kit para o tratamento de retinite pigmentosa, método para a identificação de um composto útil para o tratamento de um indivìduo que tem um pcd ocular, método para a identificação de um composto útil para o tratamento de um indivìduo que tem retinite pigmentosa, uso de um inibidor proteassomal ou um inibidor de autofagia e método para a produção de uma proteìna recombinante em uma conformação bioquimicamente funcional
|
|
EA015860B1
(ru)
|
2005-10-13 |
2011-12-30 |
Хьюман Дженом Сайенсиз, Инк. |
Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа
|
|
RU2446826C2
(ru)
|
2005-10-14 |
2012-04-10 |
Фукуока Юниверсити |
Агенты для подавления повреждения трансплантированных островков после трансплантации островков
|
|
BRPI0617664B8
(pt)
|
2005-10-21 |
2021-05-25 |
Chugai Pharmaceutical Co Ltd |
uso de um anticorpo que reconhece a il-6 para a produção de uma composição farmacêutica para tratar o enfarte do miocárdio ou suprimir a remodelagem ventricular esquerda depois do enfarte do miocárdio
|
|
KR20080080109A
(ko)
|
2005-11-04 |
2008-09-02 |
바이오겐 아이덱 엠에이 인코포레이티드 |
도파민성 뉴런의 신경돌기 성장 및 생존의 촉진 방법
|
|
EP1957115B8
(en)
|
2005-11-10 |
2014-03-05 |
Celldex Therapeutics, Inc. |
Method of treating ovarian and renal cancer using antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen
|
|
AR056806A1
(es)
|
2005-11-14 |
2007-10-24 |
Amgen Inc |
Moleculas quimericas de anticuerpo rankl- pth/ pthrp
|
|
JP5398987B2
(ja)
|
2005-11-14 |
2014-01-29 |
セルミド リミテッド |
調節性ｔ細胞の機能異常に基づく疾患の治療方法及び予防方法
|
|
AR057582A1
(es)
|
2005-11-15 |
2007-12-05 |
Nat Hospital Organization |
Agentes para suprimir la induccion de linfocitos t citotoxicos
|
|
WO2007059312A2
(en)
|
2005-11-16 |
2007-05-24 |
Ambrx, Inc. |
Methods and compositions comprising non-natural amino acids
|
|
WO2007061029A1
(ja)
|
2005-11-25 |
2007-05-31 |
Keio University |
前立腺癌治療剤
|
|
US20070213264A1
(en)
|
2005-12-02 |
2007-09-13 |
Mingdong Zhou |
Neuregulin variants and methods of screening and using thereof
|
|
EP1965827B1
(en)
|
2005-12-02 |
2015-02-25 |
Biogen Idec MA Inc. |
Treatment of conditions involving demyelination
|
|
WO2008024128A2
(en)
|
2005-12-05 |
2008-02-28 |
Simon Delagrave |
Loop-variant pdz domains as biotherapeutics, diagnostics and research reagents
|
|
CA2633956C
(en)
|
2005-12-13 |
2016-12-06 |
Olivia Raeber |
Binding proteins specific for insulin-like growth factors and uses thereof
|
|
CA2633211A1
(en)
|
2005-12-15 |
2007-06-21 |
Astrazeneca Ab |
Combination of angiopoietin-2 antagonist and of vegf-a, kdr and/or flt1 antagonist for treating cancer
|
|
CA2841386A1
(en)
|
2005-12-30 |
2007-07-12 |
Zensun (Shanghai) Science & Technology Limited |
Extended release of neuregulin for improved cardiac function
|
|
WO2007083644A1
(ja)
|
2006-01-17 |
2007-07-26 |
Dnavec Corporation |
新規タンパク質発現系
|
|
CA2640423C
(en)
|
2006-01-27 |
2016-03-15 |
Biogen Idec Ma Inc. |
Nogo receptor antagonists
|
|
WO2007086490A1
(ja)
|
2006-01-27 |
2007-08-02 |
Keio University |
脈絡膜血管新生を伴う疾患の治療剤
|
|
US9260516B2
(en)
|
2006-04-07 |
2016-02-16 |
Osaka University |
Method for promoting muscle regeneration by administering an antibody to the IL-6 receptor
|
|
TW200813091A
(en)
|
2006-04-10 |
2008-03-16 |
Amgen Fremont Inc |
Targeted binding agents directed to uPAR and uses thereof
|
|
EP2548579B1
(en)
|
2006-05-17 |
2015-09-02 |
The Ludwig Institute for Cancer Research |
Targeting VEGF-B regulation of fatty acid transporters to modulate human diseases
|
|
US20090298761A1
(en)
|
2006-05-17 |
2009-12-03 |
Donald Engelman |
Methods of treating cartilage defects using a soluble morphogenic protein complex
|
|
EP2049570B1
(en)
|
2006-06-01 |
2016-08-10 |
President and Fellows of Harvard College |
Purification of a bivalently active antibody using a non-chromatographic method
|
|
PE20080333A1
(es)
|
2006-06-08 |
2008-06-15 |
Chugai Pharmaceutical Co Ltd |
Agentes para prevenir o tratar enfermedades inflamatorias
|
|
PE20081004A1
(es)
|
2006-07-13 |
2008-09-18 |
Chugai Pharmaceutical Co Ltd |
Agentes inductores de muerte celular
|
|
EP2574625B1
(en)
|
2006-07-21 |
2015-02-25 |
HuBit genomix, Inc. |
Remedy for renal disease
|
|
AU2007279205B2
(en)
|
2006-07-28 |
2013-09-26 |
Children's Memorial Hospital |
Methods of inhibiting tumor cell aggressiveness using the microenvironment of human embryonic stem cells
|
|
CL2007002225A1
(es)
|
2006-08-03 |
2008-04-18 |
Astrazeneca Ab |
Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un
|
|
EP2054437A2
(en)
|
2006-08-07 |
2009-05-06 |
Teva Biopharmaceuticals USA, Inc. |
Albumin-insulin fusion proteins
|
|
JP5840345B2
(ja)
|
2006-09-08 |
2016-01-06 |
アンブルックス, インコーポレイテッドAmbrx, Inc. |
修飾ヒト血漿ポリペプチドまたは修飾ヒトＦｃ足場タンパク質ならびにこれらの利用
|
|
US7833527B2
(en)
|
2006-10-02 |
2010-11-16 |
Amgen Inc. |
Methods of treating psoriasis using IL-17 Receptor A antibodies
|
|
MX2009004757A
(es)
|
2006-11-14 |
2009-05-21 |
Genentech Inc |
Moduladores de regeneracion neuronal.
|
|
US7935796B2
(en)
|
2006-12-08 |
2011-05-03 |
Lexicon Pharmaceuticals, Inc. |
Monoclonal antibodies against ANGPTL3
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
CN103405768A
(zh)
|
2006-12-20 |
2013-11-27 |
爱克索马技术有限公司 |
用于治疗IL-1β相关疾病的方法
|
|
KR101496479B1
(ko)
|
2007-01-09 |
2015-02-26 |
바이오겐 아이덱 엠에이 인코포레이티드 |
Ｓｐ３５ 항체 및 그의 용도
|
|
ES2564392T3
(es)
|
2007-01-23 |
2016-03-22 |
Shinshu University |
Inhibidores de IL-6 para el tratamiento de rechazo crónico
|
|
EA017403B1
(ru)
|
2007-02-02 |
2012-12-28 |
Байоджен Айдек Эмэй Инк. |
Использование семафорина 6а в качестве промотора миелинизации и дифференцировки олигодендроцитов
|
|
US8501678B2
(en)
|
2007-03-06 |
2013-08-06 |
Atara Biotherapeutics, Inc. |
Variant activin receptor polypeptides and uses thereof
|
|
US7947646B2
(en)
|
2007-03-06 |
2011-05-24 |
Amgen Inc. |
Variant activin receptor polypeptides
|
|
CL2008000719A1
(es)
|
2007-03-12 |
2008-09-05 |
Univ Tokushima Chugai Seiyaku |
Agente terapeutico para cancer resistente a agentes quimioterapeuticos que comprende un anticuerpo que reconoce hla de clase i como ingrediente activo; composicion farmaceutica que comprende dicho anticuerpo; y metodo para tratar cancer resistente a
|
|
CN107501407B
(zh)
|
2007-03-30 |
2022-03-18 |
Ambrx公司 |
经修饰fgf-21多肽和其用途
|
|
WO2008140026A1
(ja)
|
2007-05-11 |
2008-11-20 |
Bizen Chemical Co., Ltd. |
新規のロイコトリエン受容体アンタゴニスト
|
|
EP1995227A1
(en)
|
2007-05-24 |
2008-11-26 |
Chevron USA, Inc. |
Spiro and other derivatives of diamondoids posessing therapeutic activity in the treatment of viral disorders
|
|
EP1994927A1
(en)
|
2007-05-24 |
2008-11-26 |
Chevron USA, Inc. |
Diamondoid derivatives possessing therapeutic activity in the treatment of viral disorders
|
|
JP2010534195A
(ja)
|
2007-06-27 |
2010-11-04 |
オークランド ユニサーヴィスィズ リミテッド |
アルテミン及び関連するリガンドについてのポリペプチド及びポリヌクレオチド、並びにその使用方法
|
|
EP3246045A1
(en)
|
2007-07-26 |
2017-11-22 |
Osaka University |
Therapeutic agents for ocular inflammatory disease comprising interleukin 6 receptor inhibitor as active ingredient
|
|
CA2696761C
(en)
|
2007-08-21 |
2017-02-14 |
Amgen Inc. |
Human c-fms antigen binding proteins
|
|
EP2615114B1
(en)
|
2007-08-23 |
2022-04-06 |
Amgen Inc. |
Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9)
|
|
JOP20080381B1
(ar)
|
2007-08-23 |
2023-03-28 |
Amgen Inc |
بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9)
|
|
US7982016B2
(en)
|
2007-09-10 |
2011-07-19 |
Amgen Inc. |
Antigen binding proteins capable of binding thymic stromal lymphopoietin
|
|
US20090156488A1
(en)
|
2007-09-12 |
2009-06-18 |
Zensun (Shanghai) Science & Technology Limited |
Use of neuregulin for organ preservation
|
|
TW200918553A
(en)
|
2007-09-18 |
2009-05-01 |
Amgen Inc |
Human GM-CSF antigen binding proteins
|
|
EP2040075A1
(en)
|
2007-09-24 |
2009-03-25 |
Julius-Maximilians-Universität Würzburg |
Compounds and markers for surface-enhanced raman scattering
|
|
JP5685442B2
(ja)
|
2007-09-26 |
2015-03-18 |
ウー３・フアルマ・ゲー・エム・ベー・ハーＵ３ Ｐｈａｒｍａ |
ヘパリン結合上皮成長因子様成長因子抗原結合タンパク質
|
|
BR122019021238B8
(pt)
|
2007-10-02 |
2021-07-27 |
Chugai Pharmaceutical Co Ltd |
uso de um inibidor do receptor da interleucina-6 (il-6) no tratamento da doença do enxerto versus hospedeiro (gvhd)
|
|
PT2207568T
(pt)
|
2007-11-16 |
2017-09-01 |
Univ Rockefeller |
Anticorpos específicos para a forma de protofibrilha da proteína beta-amilóide
|
|
NZ584825A
(en)
|
2007-11-20 |
2013-03-28 |
Ambrx Inc |
Modified insulin polypeptides and their uses
|
|
RU2596397C2
(ru)
|
2007-12-05 |
2016-09-10 |
Чугаи Сейяку Кабусики Кайся |
Терапевтическое средство от зуда
|
|
US20110129459A1
(en)
|
2007-12-05 |
2011-06-02 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-nr10 antibody and use thereof
|
|
US20110262425A1
(en)
|
2007-12-12 |
2011-10-27 |
National Cancer Center |
Therapeutic agent for mll leukemia and moz leukemia of which molecular target is m-csf receptor, and use thereof
|
|
MX2010006823A
(es)
|
2007-12-20 |
2010-09-30 |
Xoma Technology Ltd |
Metodos para el tratamiento de la gota.
|
|
CA2712606A1
(en)
|
2008-02-08 |
2009-08-13 |
Ambrx, Inc. |
Modified leptin polypeptides and their uses
|
|
JO2913B1
(en)
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
|
JOP20190083A1
(ar)
|
2008-06-04 |
2017-06-16 |
Amgen Inc |
بولي ببتيدات اندماجية طافرة لـfgf21 واستخداماتها
|
|
TW201503898A
(zh)
|
2008-06-05 |
2015-02-01 |
Chugai Pharmaceutical Co Ltd |
神經浸潤抑制劑
|
|
EP2687513B1
(en)
|
2008-06-09 |
2020-12-02 |
Ludwig-Maximilians-Universität München |
Drugs for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases
|
|
EP2671891A3
(en)
|
2008-06-27 |
2014-03-05 |
Amgen Inc. |
Ang-2 inhibition to treat multiple sclerosis
|
|
WO2010005570A2
(en)
|
2008-07-09 |
2010-01-14 |
Biogen Idec Ma Inc. |
Compositions comprising antibodies to lingo or fragments thereof
|
|
NZ600382A
(en)
|
2008-07-23 |
2013-11-29 |
Ambrx Inc |
Modified bovine G-CSF polypeptides and their uses
|
|
US20100129375A1
(en)
|
2008-09-10 |
2010-05-27 |
Genentech, Inc. |
Methods for inhibiting ocular angiogenesis
|
|
RU2581962C2
(ru)
|
2008-09-19 |
2016-04-20 |
Медиммун Ллк |
Нацеленные средства связывания, направленные на dll4, и их применение
|
|
NZ592250A
(en)
|
2008-09-26 |
2012-11-30 |
Lilly Co Eli |
Modified animal erythropoietin polypeptides and their uses
|
|
DK2337846T3
(da)
|
2008-09-26 |
2018-03-12 |
Ambrx Inc |
Ikke-naturlige aminosyre-replikations-afhængige mikroorganismer og vacciner
|
|
SG195542A1
(en)
|
2008-10-10 |
2013-12-30 |
Amgen Inc |
Fgf21 mutants and uses thereof
|
|
CN102317314A
(zh)
|
2008-10-10 |
2012-01-11 |
阿纳福公司 |
结合trail-r1和trail-r2的多肽
|
|
CN104689316A
(zh)
|
2008-10-22 |
2015-06-10 |
弗·哈夫曼-拉罗切有限公司 |
轴突变性的调节
|
|
KR20170105124A
(ko)
|
2008-11-26 |
2017-09-18 |
암젠 인크 |
액티빈 ｉｉｂ 수용체 폴리펩타이드의 변이체 및 이의 용도
|
|
WO2010070136A2
(en)
|
2008-12-19 |
2010-06-24 |
Centre de Recherche Public de la Santé |
Novel caviidae allergens and uses thereof
|
|
US20110312872A1
(en)
|
2008-12-22 |
2011-12-22 |
Universität Regensburg |
Norrin in the treatment of diseases associated with an increased tgf-beta activity
|
|
JO3382B1
(ar)
|
2008-12-23 |
2019-03-13 |
Amgen Inc |
أجسام مضادة ترتبط مع مستقبل cgrp بشري
|
|
US20120114667A1
(en)
|
2008-12-23 |
2012-05-10 |
Medimmune Limited |
TARGETED BINDING AGENTS DIRECTED TO a5BETA1 AND USES THEREOF
|
|
JP2012514476A
(ja)
|
2009-01-08 |
2012-06-28 |
アルバート アインシュタイン カレッジ オブ メディシン オブ イェシバ ユニバーシティ，ア ディビジョン オブ イェシバ ユニバーシティ |
細胞壁結合セラミド様糖脂質による細菌ワクチンおよびその使用
|
|
WO2010085086A2
(ko)
|
2009-01-20 |
2010-07-29 |
한올바이오파마 주식회사 |
변형된 인간 트롬보포이에틴 폴리펩타이드 절편 및 그의 제조방법
|
|
WO2010093993A2
(en)
|
2009-02-12 |
2010-08-19 |
Human Genome Sciences, Inc. |
Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance
|
|
BRPI1007983A2
(pt)
|
2009-02-13 |
2019-09-24 |
Novartis Ag |
molécula de ácido nucleico de um ''cluster'' biossintético que codifica sintases peptídicas não ribossômicas e usos da mesma
|
|
KR20110136819A
(ko)
|
2009-02-27 |
2011-12-21 |
시가 테크놀로지스, 인크. |
뎅기 바이러스 감염의 치료 및 예방을 위한 티에노피리딘 유도체
|
|
JP2010210772A
(ja)
|
2009-03-13 |
2010-09-24 |
Dainippon Screen Mfg Co Ltd |
液晶表示装置の製造方法
|
|
US9724337B2
(en)
|
2009-04-21 |
2017-08-08 |
University Of Kentucky Research Foundation |
AG-205 for the treatment of breast cancer
|
|
LT3248610T
(lt)
|
2009-05-05 |
2024-01-25 |
Amgen Inc. |
Fgf21 mutantai ir jų panaudojimas
|
|
CA2760674A1
(en)
|
2009-05-05 |
2010-11-11 |
Amgen Inc. |
Fgf21 mutants and uses thereof
|
|
EP2260857A1
(en)
|
2009-06-11 |
2010-12-15 |
Alfact Innovation |
Novel applications of HIP/PAP or derivatives thereof
|
|
IN2012DN00352A
(da)
|
2009-06-16 |
2015-08-21 |
Bikam Pharmaceuticals Inc |
|
|
JP2012530493A
(ja)
|
2009-06-17 |
2012-12-06 |
アムジエン・インコーポレーテツド |
キメラポリペプチドおよびその使用
|
|
WO2011013786A1
(ja)
|
2009-07-31 |
2011-02-03 |
Maeda Shin |
癌の転移抑制剤
|
|
TW201118166A
(en)
|
2009-09-24 |
2011-06-01 |
Chugai Pharmaceutical Co Ltd |
HLA class I-recognizing antibodies
|
|
EP2305285A1
(en)
|
2009-09-29 |
2011-04-06 |
Julius-Maximilians-Universität Würzburg |
Means and methods for treating ischemic conditions
|
|
EP2305810A1
(en)
|
2009-10-02 |
2011-04-06 |
Technische Universität München |
miRNAs in the treatment of fibrosis
|
|
TW201117824A
(en)
|
2009-10-12 |
2011-06-01 |
Amgen Inc |
Use of IL-17 receptor a antigen binding proteins
|
|
WO2011046457A1
(en)
|
2009-10-16 |
2011-04-21 |
Auckland Uniservices Limited |
Anti-neoplastic uses of artemin antagonists
|
|
WO2011049350A2
(ko)
|
2009-10-19 |
2011-04-28 |
한올바이오파마주식회사 |
변형된 인간 종양 괴사 인자 수용체-1 폴리펩티드 또는 그의 절편 및 그의 제조방법
|
|
EP3011970A3
(en)
|
2009-10-22 |
2016-06-08 |
F. Hoffmann-La Roche AG |
Modulation of axon degeneration
|
|
KR102378465B1
(ko)
|
2009-11-02 |
2022-03-28 |
유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 |
치료학적 뉴클레아제 조성물 및 방법
|
|
WO2011060372A2
(en)
|
2009-11-13 |
2011-05-19 |
Puget Sound Blood Center |
Factor viii b cell epitope variants having reduced immunogenicity
|
|
WO2011066389A1
(en)
|
2009-11-24 |
2011-06-03 |
Medimmmune, Limited |
Targeted binding agents against b7-h1
|
|
AU2010326024A1
(en)
|
2009-12-02 |
2012-07-05 |
Amgen Inc. |
Binding proteins that bind to human FGFR1c, human beta-Klotho and both human FGFR1c and human beta-Klotho
|
|
US8491927B2
(en)
|
2009-12-02 |
2013-07-23 |
Nimble Epitech, Llc |
Pharmaceutical composition containing a hypomethylating agent and a histone deacetylase inhibitor
|
|
UA109888C2
(uk)
|
2009-12-07 |
2015-10-26 |
|
ІЗОЛЬОВАНЕ АНТИТІЛО АБО ЙОГО ФРАГМЕНТ, ЩО ЗВ'ЯЗУЄТЬСЯ З β-КЛОТО, РЕЦЕПТОРАМИ FGF І ЇХНІМИ КОМПЛЕКСАМИ
|
|
NZ600363A
(en)
|
2009-12-21 |
2014-07-25 |
Ambrx Inc |
Modified porcine somatotropin polypeptides and their uses
|
|
US20120283171A1
(en)
|
2009-12-21 |
2012-11-08 |
Ambrx, Inc. |
Modified bovine somatotropin polypeptides and their uses
|
|
WO2011089161A1
(en)
|
2010-01-19 |
2011-07-28 |
Medizinische Universität Wien |
Pharmaceutical compositions comprising lignans and their derivatives for the medical management of angiogenesis and hypovascularity
|
|
CA2788021A1
(en)
|
2010-01-27 |
2011-08-04 |
Children's Medical Center Corporation |
Pro-angiogenic fragments of prominin-1 and uses thereof
|
|
US8778416B2
(en)
|
2010-02-10 |
2014-07-15 |
Nayacure Therapeutics Ltd. |
Pharmaceutical compositions and methods for the treatment and prevention of cancer
|
|
WO2011103375A1
(en)
|
2010-02-19 |
2011-08-25 |
Siga Technologies, Inc. |
Inhibitors and methods of inhibiting bacterial and viral pathogens
|
|
CN103038255A
(zh)
|
2010-03-26 |
2013-04-10 |
国立大学法人德岛大学 |
新抗cd98抗体及其用途
|
|
WO2011119906A1
(en)
|
2010-03-26 |
2011-09-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
HUMAN POLYOMAVIRUS 6 (HPyV6) AND HUMAN POLYOMAVIRUS 7 (HPyV7)
|
|
US9517264B2
(en)
|
2010-04-15 |
2016-12-13 |
Amgen Inc. |
Human FGF receptor and β-Klotho binding proteins
|
|
US20130116304A1
(en)
|
2010-04-19 |
2013-05-09 |
Ernst R. Werner |
Tmem195 encodes for tetrahydrobiopterin-dependent alkylglycerol monooxygenase activity
|
|
WO2011139595A2
(en)
|
2010-04-27 |
2011-11-10 |
Medtronic, Inc. |
Elongated biodegradable depot for sustained drug release to treat chronic pelvic pain
|
|
WO2011139594A2
(en)
|
2010-04-27 |
2011-11-10 |
Medtronic, Inc. |
Artificial bursa for intra-articular drug delivery
|
|
EP2566964B1
(en)
|
2010-05-07 |
2016-10-19 |
Centre National De La Recherche Scientifique |
Ucp1 (thermogenin) - inducing agents for use in the treatment of a disorder of the energy homeostasis
|
|
EP3190187A1
(en)
|
2010-05-21 |
2017-07-12 |
Peptimed, Inc. |
Reagents and methods for treating cancer
|
|
WO2011149046A1
(ja)
|
2010-05-28 |
2011-12-01 |
独立行政法人国立がん研究センター |
膵癌治療剤
|
|
JP6051049B2
(ja)
|
2010-05-28 |
2016-12-21 |
中外製薬株式会社 |
抗腫瘍ｔ細胞応答増強剤
|
|
EP2582720B1
(en)
|
2010-06-18 |
2014-05-21 |
XiberScience GmbH |
Peptides as active agents to stabilize biological barriers
|
|
AU2011291943B2
(en)
|
2010-08-17 |
2015-01-22 |
Ambrx, Inc. |
Modified relaxin polypeptides and their uses
|
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
|
AR083006A1
(es)
|
2010-09-23 |
2013-01-23 |
Lilly Co Eli |
Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
|
|
CN105884895B
(zh)
|
2010-09-28 |
2019-12-13 |
株式会社Nb健康研究所 |
抗人ccr7抗体、杂交瘤、核酸、载体、细胞、医药组合物和抗体固定化担载体
|
|
EP2632481A1
(en)
|
2010-10-25 |
2013-09-04 |
Regents Of The University Of Minnesota |
Therapeutic composition for treatment of glioblastoma
|
|
AU2011319843C1
(en)
|
2010-10-27 |
2017-02-02 |
Amgen Inc. |
DKK1 antibodies and methods of use
|
|
US8680045B2
(en)
|
2010-11-01 |
2014-03-25 |
Peptimed, Inc. |
Compositions of a peptide targeting system for treating cancer
|
|
TWI452135B
(zh)
|
2010-11-17 |
2014-09-11 |
中外製藥股份有限公司 |
A multiple specific antigen-binding molecule that replaces the function of Factor VIII in blood coagulation
|
|
US9023791B2
(en)
|
2010-11-19 |
2015-05-05 |
Novartis Ag |
Fibroblast growth factor 21 mutations
|
|
MX357166B
(es)
|
2010-11-24 |
2018-06-28 |
Lexicon Pharmaceuticals Inc |
Anticuerpos que se unen a notum pectinacetilesterasa.
|
|
EP4303236A3
(en)
|
2010-11-30 |
2024-03-20 |
Chugai Seiyaku Kabushiki Kaisha |
Cytotoxicity-inducing therapeutic agent
|
|
AU2011336727B2
(en)
|
2010-11-30 |
2016-11-03 |
The Johns Hopkins University |
Hybrid cyclic libraries and screens thereof
|
|
WO2012087017A2
(ko)
|
2010-12-23 |
2012-06-28 |
한올바이오파마주식회사 |
변형된 인간 종양 괴사 인자 수용체-1 폴리펩티드 또는 그의 절편 및 그의 제조방법
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
EP2668207A4
(en)
|
2011-01-24 |
2015-06-10 |
Univ Singapore |
LIPOARABINOMANNANE ANTIGEN-BINDING PROTEINS HAVING A MANNOSIS FROM PATHOGENIC MYCOBACTERIAS
|
|
BR112013018898B1
(pt)
|
2011-01-27 |
2021-10-05 |
Neuren Pharmaceuticals Limited |
Uso de ácido glicil-l-2-metilprolil-l-glutâmico e análogos do mesmo para o tratamento de transtornos do espectro do autismo
|
|
CN103649118A
(zh)
|
2011-03-01 |
2014-03-19 |
安进公司 |
双特异性结合剂
|
|
CA2834990A1
(en)
|
2011-03-10 |
2012-09-13 |
Genentech, Inc. |
Treatment of disorders with altered vascular barrier function
|
|
AU2012240231B2
(en)
|
2011-04-04 |
2017-05-25 |
University Of Iowa Research Foundation |
Methods of improving vaccine immunogenicity
|
|
CN103619881B
(zh)
|
2011-04-07 |
2017-07-28 |
安姆根有限公司 |
新的egfr结合蛋白
|
|
JP5977814B2
(ja)
|
2011-04-08 |
2016-08-24 |
アムジエン・インコーポレーテツド |
増殖分化因子１５（ｇｄｆ−１５）を使用して代謝障害を治療または改善する方法
|
|
BR112013027547B1
(pt)
|
2011-04-29 |
2021-01-19 |
University Of Washington |
polipeptídeo, dímero, composição, molécula de ácido nucleico, vetor de expressão recombinante, célula hospedeira microbiana, método para preparar o polipeptídeo e composição contendo nucleasse
|
|
MX2013012716A
(es)
|
2011-05-03 |
2014-03-21 |
Genentech Inc |
Agentes de disociacion vascular y sus usos.
|
|
MX2013013044A
(es)
|
2011-05-10 |
2014-02-20 |
Amgen Inc |
METODO PARA IDENTIFICAR COMPUESTOS QUE ESPECIFICAMENTE MODULAN LA INTERACCION DE FGFR1 Y ß-KLOTHO.
|
|
JOP20200043A1
(ar)
|
2011-05-10 |
2017-06-16 |
Amgen Inc |
طرق معالجة أو منع الاضطرابات المختصة بالكوليسترول
|
|
US9574002B2
(en)
|
2011-06-06 |
2017-02-21 |
Amgen Inc. |
Human antigen binding proteins that bind to a complex comprising β-Klotho and an FGF receptor
|
|
EA026121B1
(ru)
|
2011-06-14 |
2017-03-31 |
Бикам Фармасьютикалз, Инк. |
Опсин-связывающие лиганды, композиции и способы их использования
|
|
MX2013014847A
(es)
|
2011-06-17 |
2015-01-12 |
Amgen Inc |
Metodo para tratar o aminorar trastornos metabolicos udando clec-2.
|
|
WO2013016220A1
(en)
|
2011-07-22 |
2013-01-31 |
Amgen Inc. |
Il-17 receptor a is required for il-17c biology
|
|
WO2013017656A1
(en)
|
2011-08-02 |
2013-02-07 |
Medizinische Universität Wien |
Antagonists of ribonucleases for treating obesity
|
|
WO2013025939A2
(en)
|
2011-08-16 |
2013-02-21 |
Indiana University Research And Technology Corporation |
Compounds and methods for treating cancer by inhibiting the urokinase receptor
|
|
CA2843369A1
(en)
|
2011-08-16 |
2013-02-21 |
Evotec (Munchen) Gmbh |
Markers for susceptibility to an inhibitor of an src-family kinase
|
|
EP2744828A4
(en)
|
2011-08-16 |
2014-12-31 |
Univ Emory |
JAML-SPECIFIC BINDING AGENTS, ANTIBODIES AND USES THEREOF
|
|
AU2012301769B2
(en)
|
2011-08-31 |
2016-05-19 |
Amgen Inc. |
FGF21 for use in treating type 1 diabetes
|
|
WO2013039916A1
(en)
|
2011-09-12 |
2013-03-21 |
The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services |
Compositions for and methods of treatment and enhanced detection of non-pituitary tumors
|
|
ES2806146T3
(es)
|
2011-09-22 |
2021-02-16 |
Amgen Inc |
Proteínas de unión al antígeno CD27L
|
|
TWI593708B
(zh)
|
2011-09-26 |
2017-08-01 |
諾華公司 |
治療代謝病症之融合蛋白質
|
|
UY34347A
(es)
|
2011-09-26 |
2013-04-30 |
Novartis Ag |
Proteínas de función dual para tratar trastornos metabólicos
|
|
CN110680920A
(zh)
|
2011-09-30 |
2020-01-14 |
中外制药株式会社 |
诱导针对靶抗原的免疫应答的抗原结合分子
|
|
WO2013053076A1
(en)
|
2011-10-10 |
2013-04-18 |
Zensun （Shanghai）Science & Technology Limited |
Compositions and methods for treating heart failure
|
|
WO2013056255A1
(en)
|
2011-10-14 |
2013-04-18 |
The Board Of Trustees Of The University Of Illinois |
Methods and compositions for inhibiting tumor cell proliferation
|
|
US8906860B2
(en)
|
2011-10-14 |
2014-12-09 |
The Board Of Trustees Of The University Of Illinois |
Methods and compositions inhibiting tumor cell proliferation
|
|
CA2856703A1
(en)
|
2011-10-19 |
2013-04-25 |
Bikam Pharmaceuticals, Inc. |
Opsin-binding ligands, compositions and methods of use
|
|
KR20140091064A
(ko)
|
2011-11-16 |
2014-07-18 |
암젠 인크 |
표피 성장 인자 결실 돌연변이체 vⅲ 관련 장애를 치료하는 방법
|
|
GR1007832B
(el)
|
2011-11-21 |
2013-02-14 |
Ιδρυμα Ιατροβιολογικων Ερευνων Ακαδημιας Αθηνων, |
Αδρανοποιητες της ακτιβινης και χρηση τους για την θεραπεια ασθενειων που σχετιζονται με παρεκκλινουσα ενεργοποιηση της "αμυντικης αποκρισης του ξενιστη"
|
|
CA2862807A1
(en)
|
2011-11-30 |
2013-06-06 |
Bikam Pharmaceuticals, Inc. |
Opsin-binding ligands, compositions and methods of use
|
|
EP2785178B1
(en)
|
2011-12-01 |
2019-05-01 |
Bikam Pharmaceuticals, Inc. |
Opsin-binding ligands, compositions and methods of use
|
|
EP2601941A1
(en)
|
2011-12-06 |
2013-06-12 |
Ludwig-Maximilians-Universität München |
Beta-O/S/N fatty acid based compounds as antibacterial and antiprotozoal agents
|
|
WO2013086443A1
(en)
|
2011-12-08 |
2013-06-13 |
Amgen Inc. |
Agonistic human lcat antigen binding proteins and their use in therapy
|
|
WO2013083810A1
(en)
|
2011-12-09 |
2013-06-13 |
F. Hoffmann-La Roche Ag |
Identification of non-responders to her2 inhibitors
|
|
EP3050900A1
(en)
|
2011-12-19 |
2016-08-03 |
Xoma (Us) Llc |
Methods for treating acne
|
|
PE20142114A1
(es)
|
2011-12-19 |
2015-01-04 |
Amgen Inc |
Polipeptidos de receptores de activina variantes, solos o en combinacion con quimioterapia, y sus usos
|
|
US10774132B2
(en)
|
2012-01-09 |
2020-09-15 |
The Scripps Research Instittue |
Ultralong complementarity determining regions and uses thereof
|
|
US20150011431A1
(en)
|
2012-01-09 |
2015-01-08 |
The Scripps Research Institute |
Humanized antibodies
|
|
US9512212B2
(en)
|
2012-01-11 |
2016-12-06 |
Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acting For And On Behalf Of Arizona State University |
Bispecific antibody fragments for neurological disease proteins and methods of use
|
|
JP2015506373A
(ja)
|
2012-01-26 |
2015-03-02 |
アムジエン・インコーポレーテツド |
成長分化因子１５（ｇｄｆ−１５）ポリペプチド
|
|
EP2626066A1
(en)
|
2012-02-10 |
2013-08-14 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Combination therapy comprising selective VEGFR-2 inhibitors and MEK inhibitors
|
|
EP2814486B8
(en)
|
2012-02-17 |
2018-05-23 |
Kineta Viral Hemorrhagic Fever, LLC |
Antiviral drugs for treatment of arenavirus infection
|
|
CN104271772A
(zh)
|
2012-03-29 |
2015-01-07 |
科罗拉多州立大学董事会,公司实体 |
点击核酸
|
|
WO2013161814A1
(ja)
|
2012-04-23 |
2013-10-31 |
ジーンフロンティア株式会社 |
抗ヒトｃｄ６９抗体、及びその医薬用途
|
|
EA039663B1
(ru)
|
2012-05-03 |
2022-02-24 |
Амген Инк. |
Применение антитела против pcsk9 для снижения сывороточного холестерина лпнп и лечения связанных с холестерином расстройств
|
|
UY34813A
(es)
|
2012-05-18 |
2013-11-29 |
Amgen Inc |
Proteínas de unión a antígeno dirigidas contra el receptor st2
|
|
EP2666775A1
(en)
|
2012-05-21 |
2013-11-27 |
Domain Therapeutics |
Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group II metabotropic glutamate receptors
|
|
US9844582B2
(en)
|
2012-05-22 |
2017-12-19 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with extended-PK IL-2 and therapeutic agents
|
|
CN104271566B
(zh)
|
2012-05-22 |
2017-05-31 |
霍夫曼-拉罗奇有限公司 |
取代的联吡啶胺及其用途
|
|
SG11201408284VA
(en)
|
2012-05-22 |
2015-02-27 |
Xenon Pharmaceuticals Inc |
N-substituted benzamides and their use in the treatment of pain
|
|
US9944685B2
(en)
|
2012-07-02 |
2018-04-17 |
Medizinische Universität Wien |
Complement split product C4d for the treatment of inflammatory conditions
|
|
WO2014008458A2
(en)
|
2012-07-06 |
2014-01-09 |
Genentech, Inc. |
N-substituted benzamides and methods of use thereof
|
|
EP2687225A1
(en)
|
2012-07-19 |
2014-01-22 |
Alfact Innovation |
HIP/PAP protein and derivatives thereof for use in treating cancer
|
|
EP2695950A1
(en)
|
2012-08-10 |
2014-02-12 |
Blackfield AG |
Markers for responsiveness to an inhibitor of the fibroblast growth factor receptor
|
|
JP2015526471A
(ja)
|
2012-08-21 |
2015-09-10 |
ジェネシス リサーチ インスティチュート |
アントラサイクリン誘発性心毒性を治療または予防するための組成物および方法
|
|
CN104684899B
(zh)
|
2012-09-27 |
2017-07-04 |
霍夫曼-拉罗奇有限公司 |
取代的磺酰胺化合物
|
|
MX366163B
(es)
|
2012-10-17 |
2019-07-01 |
Vascular Biogenics Ltd |
Composiciones de adenovirus.
|
|
US9309318B2
(en)
|
2012-10-17 |
2016-04-12 |
Amgen, Inc. |
Compositions relating to anti-IL-21 receptor antibodies
|
|
CA2890862C
(en)
|
2012-11-09 |
2021-10-12 |
Genefrontier Corporation |
Anti-adam28 antibody for treating cancer
|
|
UY35148A
(es)
|
2012-11-21 |
2014-05-30 |
Amgen Inc |
Immunoglobulinas heterodiméricas
|
|
JP6998646B2
(ja)
|
2012-11-30 |
2022-02-04 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
Ｐｄ－ｌ１阻害剤併用療法を必要とする患者の同定
|
|
TW201425336A
(zh)
|
2012-12-07 |
2014-07-01 |
Amgen Inc |
Ｂｃｍａ抗原結合蛋白質
|
|
RU2015131314A
(ru)
|
2013-01-18 |
2017-02-27 |
Ф. Хоффманн-Ля Рош Аг |
3-замещенные пиразолы и их применение в качестве ингибиторов dlk
|
|
ES2728936T3
(es)
|
2013-01-25 |
2019-10-29 |
Amgen Inc |
Anticuerpos dirigidos contra CDH19 para melanoma
|
|
JO3519B1
(ar)
|
2013-01-25 |
2020-07-05 |
Amgen Inc |
تركيبات أجسام مضادة لأجل cdh19 و cd3
|
|
SG11201505960VA
(en)
|
2013-02-01 |
2015-08-28 |
Santa Maria Biotherapeutics Inc |
Administration of an anti-activin-a compound to a subject
|
|
US9371352B2
(en)
|
2013-02-08 |
2016-06-21 |
Vaccinex, Inc. |
Modified glycolipids and methods of making and using the same
|
|
US9458246B2
(en)
|
2013-03-13 |
2016-10-04 |
Amgen Inc. |
Proteins specific for BAFF and B7RP1
|
|
JOP20140087B1
(ar)
|
2013-03-13 |
2021-08-17 |
Amgen Inc |
بروتينات مخصصة ل baff و b7rp1 وإستخداماتها
|
|
US9580486B2
(en)
|
2013-03-14 |
2017-02-28 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of T-regulatory cells
|
|
CN105263490B
(zh)
|
2013-03-14 |
2018-05-22 |
基因泰克公司 |
取代的三唑并吡啶及其使用方法
|
|
AU2014244444A1
(en)
|
2013-03-14 |
2015-09-24 |
Amgen Inc. |
CHRDL-1 antigen binding proteins and methods of treatment
|
|
US9505849B2
(en)
|
2013-03-15 |
2016-11-29 |
Amgen Research (Munich) Gmbh |
Antibody constructs for influenza M2 and CD3
|
|
JP6434485B2
(ja)
|
2013-03-15 |
2018-12-05 |
アムジエン・インコーポレーテツド |
Ｐｌａ２ｇ１２ａポリペプチド及びｐｌａ２ｇ１２ａ変異ポリペプチドを使用して代謝障害を治療する方法
|
|
WO2014144553A1
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Inc. |
Secreted frizzle-related protein 5 (sfrp5) binding proteins and methods of treatment
|
|
CN105143267B
(zh)
|
2013-03-15 |
2020-06-26 |
美国安进公司 |
人pac1抗体
|
|
EP3653642A1
(en)
|
2013-03-15 |
2020-05-20 |
Amgen Research (Munich) GmbH |
Single chain binding molecules comprising n-terminal abp
|
|
JP6469644B2
(ja)
|
2013-03-15 |
2019-02-13 |
アムジエン・インコーポレーテツド |
抗ｃｃｒ７抗原結合タンパク質に関係する方法および組成物
|
|
WO2014144817A2
(en)
|
2013-03-15 |
2014-09-18 |
Amgen Inc. |
Inhibitory polypeptides specific to wnt inhibitors
|
|
MX2015015130A
(es)
|
2013-05-01 |
2016-02-18 |
Hoffmann La Roche |
Compuestos de biheteroarilo y usos de los mismos.
|
|
MX2015014861A
(es)
|
2013-05-01 |
2016-03-09 |
Hoffmann La Roche |
Pirimidinas sustituidas con heterocicloalquilo c-enlazado y sus usos.
|
|
EP3461909A1
(en)
|
2013-05-21 |
2019-04-03 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Isoforms of gata6 and nkx2-1 as markers for diagnosis and therapy of cancer and as targets for anti-cancer therapy
|
|
KR20230132635A
(ko)
|
2013-05-22 |
2023-09-15 |
젠순 (상하이) 사이언스 앤드 테크놀로지 캄파니 리미티드 |
심부전을 치료하기 위한 뉴레귤린의 연장 방출
|
|
WO2014193800A2
(en)
|
2013-05-28 |
2014-12-04 |
The Johns Hopkins University |
Aptamers for the treatment of sickle cell disease
|
|
ES2895824T3
(es)
|
2013-05-30 |
2022-02-22 |
Kiniksa Pharmaceuticals Ltd |
Proteínas de enlace al antígeno del receptor de oncastatina M
|
|
EP2810648A1
(en)
|
2013-06-04 |
2014-12-10 |
Daniel Rauh |
Targeting domain-domain interaction for the identification of kinase modulators
|
|
EP3009518B1
(en)
|
2013-06-11 |
2020-08-12 |
National Center of Neurology and Psychiatry |
Method for predicting post-therapy prognosis of relapsing-remitting multiple sclerosis (rrms) patient, and method for determining applicability of novel therapy
|
|
EP2835135A3
(en)
|
2013-06-19 |
2015-06-24 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin |
Means and methods for treating pseudomonas infection
|
|
WO2014207213A1
(en)
|
2013-06-28 |
2014-12-31 |
Medizinische Universität Innsbruck |
Novel inhibitors of protein kinase c epsilon signaling
|
|
JP6267792B2
(ja)
|
2013-06-28 |
2018-01-24 |
アムジエン・インコーポレーテツド |
ホモ接合性家族性高コレステロール血症の治療方法
|
|
WO2015006744A1
(en)
|
2013-07-11 |
2015-01-15 |
The California Institute For Biomedical Research |
Immunoglobulin fusion proteins and compositions thereof
|
|
WO2015017146A2
(en)
|
2013-07-18 |
2015-02-05 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
|
KR20240000642A
(ko)
|
2013-07-31 |
2024-01-02 |
암젠 인크 |
성장 분화 인자 15(ｇｄｆ-15) 작제물
|
|
WO2015022326A1
(en)
|
2013-08-12 |
2015-02-19 |
Xiber Science Gmbh |
Peptides as active agents for treating primary graft dysfunction
|
|
TW201605896A
(zh)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
Gitr抗原結合蛋白
|
|
AU2014318017B2
(en)
|
2013-09-05 |
2020-02-06 |
Amgen Inc. |
Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles
|
|
CA2923835C
(en)
|
2013-09-11 |
2022-11-29 |
The Administrators Of The Tulane Educational Fund |
Novel anthranilic amides and the use thereof
|
|
TWI688401B
(zh)
|
2013-09-13 |
2020-03-21 |
美商安進公司 |
用於治療骨髓性白血病的表觀遺傳因子與靶向ｃｄ３３及ｃｄ３之雙特異性化合物的組合
|
|
KR102302634B1
(ko)
|
2013-09-13 |
2021-09-14 |
더 스크립스 리서치 인스티튜트 |
변형된 치료제 및 이의 조성물
|
|
ES2577289T3
(es)
|
2013-09-16 |
2016-07-14 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Calreticulina mutante para el diagnóstico de malignidades mieloides
|
|
US20160229922A1
(en)
|
2013-09-20 |
2016-08-11 |
Chugai Seiyaku Kabushiki Kaisha |
Treatment for hemorrhagic diseases by anti-protein-c antibody
|
|
ES2724300T3
(es)
|
2013-09-25 |
2019-09-10 |
Univ Cornell |
Compuestos para inducir inmunidad antitumoral y métodos de lo mismo
|
|
DK3052102T3
(da)
|
2013-10-04 |
2020-03-09 |
Aptose Biosciences Inc |
Sammensætninger til behandling af cancere
|
|
TR201902249T4
(tr)
|
2013-10-11 |
2019-03-21 |
Hoffmann La Roche |
Trpa1 modülatörleri olarak faydalı ornatık heterosiklik sülfonamit bileşikleri.
|
|
ES2741308T3
(es)
|
2013-10-15 |
2020-02-10 |
Scripps Research Inst |
Interruptores de células T con receptores de antígenos quiméricos y usos de los mismos
|
|
JP6734774B2
(ja)
|
2013-10-15 |
2020-08-05 |
ザ スクリプス リサーチ インスティテュート |
ペプチドキメラ抗原受容体ｔ細胞スイッチおよびその使用
|
|
AU2014335251B2
(en)
|
2013-10-15 |
2020-04-30 |
Genefrontier Corporation |
Human antibody against aggrecanase-type ADAMTS species for therapeutics of aggrecanase-related diseases
|
|
EP3057605A1
(en)
|
2013-10-18 |
2016-08-24 |
Novartis AG |
Methods of treating diabetes and related disorders
|
|
US10988745B2
(en)
|
2013-10-31 |
2021-04-27 |
Resolve Therapeutics, Llc |
Therapeutic nuclease-albumin fusions and methods
|
|
US10039809B2
(en)
|
2013-12-18 |
2018-08-07 |
The California Institute For Biomedical Research |
Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof
|
|
MX2016008110A
(es)
|
2013-12-20 |
2016-08-19 |
Hoffmann La Roche |
Derivados de pirazol como inhibidores de la cinasa de cremallera de leucina dual (dlk) y usos de los mismos.
|
|
CN103965357B
(zh)
|
2013-12-31 |
2016-08-17 |
嘉和生物药业有限公司 |
一种抗人rankl抗体
|
|
WO2015110930A1
(en)
|
2014-01-24 |
2015-07-30 |
Pfizer Inc. |
Modified interleukin 21 receptor proteins
|
|
WO2015120187A1
(en)
|
2014-02-05 |
2015-08-13 |
The University Of Chicago |
Chimeric antigen receptors recognizing cancer-spevific tn glycopeptide variants
|
|
EP3104873B1
(en)
|
2014-02-13 |
2019-09-04 |
Technische Universität München |
Fgf-8 for use in treating diseases or disorders of energy homeostasis
|
|
EP3107935B1
(en)
|
2014-02-20 |
2020-06-24 |
Allergan, Inc. |
Complement component c5 antibodies
|
|
WO2015130826A1
(en)
|
2014-02-27 |
2015-09-03 |
Allergan, Inc. |
COMPLEMENT FACTOR Bb ANTIBODIES
|
|
JP2017508798A
(ja)
|
2014-03-07 |
2017-03-30 |
ザ ジョンズ ホプキンス ユニバーシティ |
ヒストンリジン特異的デメチラーゼ（ｌｓｄ１）およびヒストンデアセチラーゼ（ｈｄａｃ）の阻害剤
|
|
US10507227B2
(en)
|
2014-04-15 |
2019-12-17 |
The Hospital For Sick Children |
Cationic antimicrobial peptides
|
|
WO2015173398A1
(en)
|
2014-05-15 |
2015-11-19 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Antagonists of slc38a9 and their use in therapy
|
|
WO2015179415A1
(en)
|
2014-05-19 |
2015-11-26 |
Novartis Ag |
Methods of treating anorexia
|
|
EP2947460A1
(en)
|
2014-05-22 |
2015-11-25 |
Medizinische Universität Wien |
Personalized therapy of inflammation-associated cancer using methods of assessing the susceptibility of a subject to the treatment with EGFR inhibitors/antagonists
|
|
US11357748B2
(en)
|
2014-05-30 |
2022-06-14 |
The Johns Hopkins University |
Methods for treating mendelian disorders of the epigenetic machinery
|
|
MX355107B
(es)
|
2014-06-03 |
2018-04-04 |
Xbiotech Inc |
Composiciones y metodos para tratar y prevenir infecciones por staphylococcus aureus.
|
|
AR100689A1
(es)
|
2014-06-09 |
2016-10-26 |
Ultragenyx Pharmaceutical Inc |
Control del fosfato sérico para una osificación óptima
|
|
EP3155008B1
(en)
|
2014-06-13 |
2020-08-26 |
Atara Biotherapeutics, Inc. |
Formulated receptor polypeptides and related methods
|
|
TWI831106B
(zh)
|
2014-06-20 |
2024-02-01 |
日商中外製藥股份有限公司 |
用於因第viii凝血因子及/或活化的第viii凝血因子的活性降低或欠缺而發病及/或進展的疾病之預防及/或治療之醫藥組成物
|
|
EP3166939B1
(en)
|
2014-07-07 |
2019-06-05 |
Genentech, Inc. |
Therapeutic compounds and methods of use thereof
|
|
US10166304B2
(en)
|
2014-07-11 |
2019-01-01 |
Regents Of The University Of Minnesota |
Antibody fragments for detecting cancer and methods of use
|
|
AU2015294834B2
(en)
|
2014-07-31 |
2021-04-29 |
Amgen Research (Munich) Gmbh |
Optimized cross-species specific bispecific single chain antibody constructs
|
|
AR101669A1
(es)
|
2014-07-31 |
2017-01-04 |
Amgen Res (Munich) Gmbh |
Constructos de anticuerpos para cdh19 y cd3
|
|
WO2016025647A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and a cancer vaccine
|
|
EP3180018B1
(en)
|
2014-08-12 |
2019-07-24 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2 and integrin-binding-fc-fusion protein
|
|
EP3183346B1
(en)
|
2014-08-22 |
2024-10-23 |
Auckland Uniservices Limited |
Channel modulators
|
|
CN106714811A
(zh)
|
2014-08-27 |
2017-05-24 |
佩普蒂梅德股份有限公司 |
抗肿瘤组合物和方法
|
|
WO2016040767A2
(en)
|
2014-09-12 |
2016-03-17 |
Amgen Inc. |
Chrdl-1 epitopes and antibodies
|
|
EP3000814A1
(en)
|
2014-09-26 |
2016-03-30 |
Domain Therapeutics |
Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group II metabotropic glutamate receptors
|
|
CN107148279B
(zh)
|
2014-10-21 |
2021-09-03 |
赛生药品股份国际有限公司 |
用免疫刺激剂治疗癌症
|
|
CN114805532A
(zh)
|
2014-10-24 |
2022-07-29 |
百时美施贵宝公司 |
修饰的fgf-21多肽及其用途
|
|
WO2016069889A1
(en)
|
2014-10-31 |
2016-05-06 |
Resolve Therapeutics, Llc |
Therapeutic nuclease-transferrin fusions and methods
|
|
WO2016079321A1
(en)
|
2014-11-20 |
2016-05-26 |
Cemm Forschungszentrum Für Molekulare Medizin Gmbh |
Antagonists of setdb2 for use in the therapy of infectious diseases
|
|
EP3085709B1
(en)
|
2014-12-28 |
2019-08-21 |
Genor Biopharma Co., Ltd |
Humanized anti-human rankl antibody, pharmaceutical composition and use thereof
|
|
WO2016123143A1
(en)
|
2015-01-26 |
2016-08-04 |
The University Of Chicago |
CAR T-CELLS RECOGNIZING CANCER-SPECIFIC IL 13Rα2
|
|
EP3250609A4
(en)
|
2015-01-26 |
2018-07-11 |
The University of Chicago |
Il13ra alpha 2 binding agents and use thereof in cancer treatment
|
|
WO2016135140A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
4-aminoquinazoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
US10906948B2
(en)
|
2015-02-23 |
2021-02-02 |
Seagull Therapeutics Sas |
Non-natural Semaphorins 3 and their medical use
|
|
WO2016135139A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
2,3-dihydrocyclopenta[b]quinoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
WO2016135138A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Oxoquinoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
WO2016135137A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Substituted 4-(phenylamino)quinoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
US10774148B2
(en)
|
2015-02-27 |
2020-09-15 |
Chugai Seiyaku Kabushiki Kaisha |
Composition for treating IL-6-related diseases
|
|
EP3268373B1
(en)
|
2015-03-09 |
2022-04-27 |
F. Hoffmann-La Roche AG |
Tricyclic dlk inhibitors and uses thereof
|
|
WO2016154621A1
(en)
|
2015-03-26 |
2016-09-29 |
The California Institute For Biomedical Research |
SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
|
|
TN2017000432A1
(en)
|
2015-04-10 |
2019-04-12 |
Amgen Inc |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
|
EP3283113A4
(en)
|
2015-04-15 |
2018-12-05 |
The California Institute for Biomedical Research |
Optimized pne-based chimeric receptor t cell switches and uses thereof
|
|
WO2016166360A1
(en)
|
2015-04-17 |
2016-10-20 |
Bayer Pharma Aktiengesellschaft |
Bispecific antibody constructs for cdh3 and cd3
|
|
EP3285753A1
(en)
|
2015-04-22 |
2018-02-28 |
CeMM - Forschungszentrum für Molekulare Medizin GmbH |
Combination of an antiandrogen with a vitamin k antagonist or with a gamma -glutamyl carboxylase inhibitor for the therapy of androgen receptor positive cancer
|
|
EP3294072A4
(en)
|
2015-05-15 |
2019-03-13 |
The Johns Hopkins University |
NOVEL PRENATAL FOOD SUPPLEMENT WITH FLUORIDE
|
|
KR20180008761A
(ko)
|
2015-05-22 |
2018-01-24 |
제넨테크, 인크. |
치환된 벤즈아미드 및 이의 이용 방법
|
|
US20160361380A1
(en)
|
2015-06-12 |
2016-12-15 |
Nymox Corporation |
Combination compositions for treating disorders requiring removal or destruction of unwanted cellular proliferations
|
|
WO2016205488A1
(en)
|
2015-06-17 |
2016-12-22 |
The California Institute For Biomedical Research |
Modified therapeutic agents and compositions thereof
|
|
US10676490B2
(en)
|
2015-07-07 |
2020-06-09 |
Florida Southwestern State College |
Use of amine carboxyboranes as therapeutic delivery of carbon monoxide and as general drug delivery system in the presence of reactive oxygen species
|
|
WO2017023791A1
(en)
|
2015-07-31 |
2017-02-09 |
The Johns Hopkins University |
Glutamine antagonists for the treatment of cognitive deficits
|
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究（慕尼黑）公司 |
Ｍｓｌｎ及ｃｄ３抗體構築體
|
|
US10842763B2
(en)
|
2015-07-31 |
2020-11-24 |
The Johns Hopkins University |
Methods for cancer and immunotherapy using prodrugs of glutamine analogs
|
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究（慕尼黑）公司 |
Egfrviii及cd3抗體構築體
|
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究（慕尼黑）公司 |
Dll3及cd3抗體構築體
|
|
WO2017023793A2
(en)
|
2015-07-31 |
2017-02-09 |
The Johns Hopkins University |
Methods for cancer and immunotherapy using glutamine analogues, including don
|
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究（慕尼黑）公司 |
Ｃｄ７０及ｃｄ３抗體構築體
|
|
PL3328827T3
(pl)
|
2015-07-31 |
2023-11-27 |
The Johns Hopkins University |
Proleki analogów glutaminy
|
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究（慕尼黑）公司 |
Ｆｌｔ３及ｃｄ３抗體構築體
|
|
JO3620B1
(ar)
|
2015-08-05 |
2020-08-27 |
Amgen Res Munich Gmbh |
مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم
|
|
CN108137477A
(zh)
|
2015-08-27 |
2018-06-08 |
基因泰克公司 |
治疗化合物及其使用方法
|
|
JP6951825B2
(ja)
|
2015-09-04 |
2021-10-20 |
ザ スクリプス リサーチ インスティテュート |
インスリン免疫グロブリン融合タンパク質
|
|
WO2017059371A1
(en)
|
2015-10-01 |
2017-04-06 |
Amgen Inc. |
Treatment of bile acid disorders
|
|
EP4410376A3
(en)
|
2015-11-03 |
2024-10-30 |
Regents of the University of Minnesota |
Cd200 inhibitors and methods of use thereof
|
|
JP2019503985A
(ja)
|
2015-11-03 |
2019-02-14 |
グリコミメティクス， インコーポレイテッド |
モノクローナル抗体、造血幹細胞の産生のための方法および組成物、ならびにそれらを使用する方法
|
|
KR20180097542A
(ko)
|
2015-11-13 |
2018-08-31 |
마발론 테라퓨틱스 리미티드 |
그룹 ii 대사성 글루타메이트 수용체의 알로스테릭 조절제로서의 치환된 트리사이클릭 1,4-벤조디아제피논 유도체
|
|
US11660340B2
(en)
|
2015-11-18 |
2023-05-30 |
Chugai Seiyaku Kabushiki Kaisha |
Combination therapy using T cell redirection antigen binding molecule against cell having immunosuppressing function
|
|
EP3378488A4
(en)
|
2015-11-18 |
2019-10-30 |
Chugai Seiyaku Kabushiki Kaisha |
METHOD FOR ENHANCING THE HUMORAL IMMUNE RESPONSE
|
|
EP3380466A1
(en)
|
2015-11-25 |
2018-10-03 |
Genentech, Inc. |
Substituted benzamides useful as sodium channel blockers
|
|
US20170157215A1
(en)
|
2015-12-04 |
2017-06-08 |
Jomoco, Corp. |
Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates
|
|
CN108368143B
(zh)
|
2015-12-09 |
2022-02-01 |
维也纳医科大学 |
用于癌症疗法的单马来酰亚胺官能化的铂化合物
|
|
DK3387019T3
(da)
|
2015-12-09 |
2022-01-10 |
Scripps Research Inst |
Relaxin-immunoglobulinfusionsproteiner og anvendelsesfremgangsmåder
|
|
EA201891323A1
(ru)
|
2015-12-23 |
2019-02-28 |
Амген Инк. |
Способ лечения или облегчения метаболических нарушений с использованием белков, связывающих рецептор желудочного ингибиторного пептида (gipr), в комбинации с агонистами glp-1
|
|
WO2017110980A1
(ja)
|
2015-12-25 |
2017-06-29 |
中外製薬株式会社 |
増強された活性を有する抗体及びその改変方法
|
|
WO2017121855A1
(en)
|
2016-01-15 |
2017-07-20 |
Universität Hamburg |
Flavonoide-type compounds bearing an o-rhamnosyl residue
|
|
JOP20170017B1
(ar)
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
EP3411404B1
(en)
|
2016-02-03 |
2022-11-09 |
Amgen Research (Munich) GmbH |
Psma and cd3 bispecific t cell engaging antibody constructs
|
|
AU2017216230B2
(en)
|
2016-02-03 |
2023-07-06 |
Amgen Inc. |
BCMA and CD3 bispecific T cell engaging antibody constructs
|
|
US10098909B2
(en)
|
2016-02-05 |
2018-10-16 |
University Of South Florida |
Ionic cocrystal of lithium, lispro, for the treatment of fragile X syndrome
|
|
CN109073649A
(zh)
|
2016-02-10 |
2018-12-21 |
新泽西鲁特格斯州立大学 |
用于诊断和治疗结核分枝杆菌感染的新颖抗lam和抗pim6/lam单克隆抗体
|
|
EP3416947A1
(en)
|
2016-02-15 |
2018-12-26 |
CeMM - Forschungszentrum für Molekulare Medizin GmbH |
Taf1 inhibitors for the therapy of cancer
|
|
EP3216458A1
(en)
|
2016-03-07 |
2017-09-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Modified vascular endothelial growth factor a (vegf-a) and its medical use
|
|
BR112018068363A2
(pt)
|
2016-03-14 |
2019-01-15 |
Chugai Pharmaceutical Co Ltd |
fármaco terapêutico indutor de dano celular para uso em terapia de câncer
|
|
JP2019513714A
(ja)
|
2016-03-30 |
2019-05-30 |
ジェネンテック， インコーポレイテッド |
置換ベンズアミド及びその使用方法
|
|
GB2555264A
(en)
|
2016-04-15 |
2018-04-25 |
Univ Oxford Innovation Ltd |
Adenosine receptor modulators for the treatment of circadian rhythm disorders
|
|
EP3808764A1
(en)
|
2016-05-04 |
2021-04-21 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
|
US10183058B2
(en)
|
2016-06-17 |
2019-01-22 |
Nymox Corporation |
Method of preventing or reducing the progression of prostate cancer
|
|
MA45554A
(fr)
|
2016-07-01 |
2019-05-08 |
Resolve Therapeutics Llc |
Fusions de binucléase optimisées.
|
|
US10300145B2
(en)
|
2016-07-15 |
2019-05-28 |
Massachusetts Institute Of Technology |
Synthetic nanoparticles for delivery of immunomodulatory compounds
|
|
JP6975515B2
(ja)
|
2016-07-20 |
2021-12-01 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Ｔｒｐａ１モデュレーターとしてのスルホニルシクロアルキルカルボキサミド化合物
|
|
CN109476640B
(zh)
|
2016-07-20 |
2022-02-25 |
豪夫迈·罗氏有限公司 |
双环脯氨酸化合物
|
|
US10172910B2
(en)
|
2016-07-28 |
2019-01-08 |
Nymox Corporation |
Method of preventing or reducing the incidence of acute urinary retention
|
|
US20200030295A1
(en)
|
2016-08-02 |
2020-01-30 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Heterocyclic diamidines
|
|
WO2018031454A1
(en)
|
2016-08-08 |
2018-02-15 |
Amgen Inc. |
Method of improving connective tissue attachment using anti-sclerostin antibodies
|
|
CN109803964A
(zh)
|
2016-08-12 |
2019-05-24 |
豪夫迈·罗氏有限公司 |
磺酰基吡啶基trp抑制剂
|
|
WO2018044970A1
(en)
|
2016-08-31 |
2018-03-08 |
University Of Rochester |
Human monoclonal antibodies to human endogenous retrovirus k envelope (herv-k) and uses thereof
|
|
BR112019003989A2
(pt)
|
2016-09-06 |
2019-05-28 |
Chugai Pharmaceutical Co Ltd |
métodos de utilização de um anticorpo biespecífico que reconhece o fator de coagulação ix e/ou o fator de coagulação ix ativado e o fator de coagulação x e/ou o fator de coagulação x ativado
|
|
US10532081B2
(en)
|
2016-09-07 |
2020-01-14 |
Nymox Corporation |
Method of ameliorating or preventing the worsening or the progression of symptoms of BPH
|
|
MX2019000735A
(es)
|
2016-09-16 |
2019-12-02 |
Res Triangle Inst |
Antagonistas opioides kappa de tetrahidroisoquinolina.
|
|
WO2018073193A1
(en)
|
2016-10-17 |
2018-04-26 |
F. Hoffmann-La Roche Ag |
Bicyclic pyridone lactams and methods of use thereof
|
|
US11174306B2
(en)
|
2016-10-19 |
2021-11-16 |
The Scripps Research Institute |
Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
|
|
KR20190103154A
(ko)
|
2016-11-14 |
2019-09-04 |
체엠엠 - 포르슝스첸트룸 퓨어 몰레쿨라레 메디친 게엠베하 |
암의 치료법을 위한 brd4 억제제 및 항폴레이트의 조합
|
|
EP3544979B1
(en)
|
2016-11-28 |
2021-08-04 |
F. Hoffmann-La Roche AG |
Oxadiazolones as transient receptor potential channel inhibitors
|
|
US11091490B2
(en)
|
2016-11-30 |
2021-08-17 |
Medizinische Universität Innsbruck |
3-amino-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-ones as cyclin dependent kinase inhibitors
|
|
TW201831478A
(zh)
|
2016-12-02 |
2018-09-01 |
瑞士商赫孚孟拉羅股份公司 |
雙環醯胺化合物及其使用方法
|
|
US11072607B2
(en)
|
2016-12-16 |
2021-07-27 |
Genentech, Inc. |
Inhibitors of RIP1 kinase and methods of use thereof
|
|
MX2019008029A
(es)
|
2017-01-06 |
2019-12-11 |
Abl Bio Inc |
Anticuerpo anti-alfa-sinucleina y su uso.
|
|
EP3567054A4
(en)
|
2017-01-06 |
2021-03-10 |
ABL Bio Inc. |
ANTI-ALPHA SYN ANTIBODIES AND USES THEREOF
|
|
CA3049656A1
(en)
|
2017-01-10 |
2018-07-19 |
Nodus Therapeutics |
Combination tumor treatment with an integrin-binding-fc fusion protein and immune modulator
|
|
US10350266B2
(en)
|
2017-01-10 |
2019-07-16 |
Nodus Therapeutics, Inc. |
Method of treating cancer with a multiple integrin binding Fc fusion protein
|
|
US20190328792A1
(en)
|
2017-01-11 |
2019-10-31 |
Paracelsus Medizinische Privatuniversität Salzburg - Privatstiftung |
Mesenchymal stem cell-derived extracellular vesicles and their medical use
|
|
JOP20190177A1
(ar)
|
2017-01-17 |
2019-07-16 |
Amgen Inc |
طريقة لعلاج أو تحسين اضطرابات أيضية باستخدام مساعدات مستقبل glp-1 مقترنة بمناهضات لمستقبل ببتيد مثبط معوي (gipr)
|
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
|
BR112019016139A2
(pt)
|
2017-02-08 |
2020-04-07 |
Bristol-Myers Squibb Company |
polipeptídio de relaxina modificada compreendendo um melhorador farmacocinético e usos do mesmo
|
|
US10335453B2
(en)
|
2017-03-01 |
2019-07-02 |
Nymox Corporation |
Compositions and methods for improving sexual function
|
|
WO2018160791A1
(en)
|
2017-03-03 |
2018-09-07 |
Massachusetts Institute Of Technology |
Antimicrobial constructs and uses thereof
|
|
WO2018162607A1
(en)
|
2017-03-07 |
2018-09-13 |
F. Hoffmann-La Roche Ag |
Oxadiazole transient receptor potential channel inhibitors
|
|
US10793550B2
(en)
|
2017-03-24 |
2020-10-06 |
Genentech, Inc. |
4-piperidin-n-(pyrimidin-4-yl)chroman-7-sulfonamide derivatives as sodium channel inhibitors
|
|
EP3620531A4
(en)
|
2017-05-02 |
2021-03-17 |
National Center of Neurology and Psychiatry |
METHOD OF PREDICTION AND EVALUATION OF THERAPEUTIC EFFECT IN DISEASES RELATING TO IL-6 AND NEUTROPHILS
|
|
US11918650B2
(en)
|
2017-05-05 |
2024-03-05 |
Amgen Inc. |
Pharmaceutical composition comprising bispecific antibody constructs for improved storage and administration
|
|
CA3063288A1
(en)
|
2017-05-12 |
2018-11-15 |
Mavalon Therapeutics Limited |
Substituted heterocyclic compounds as allosteric modulators of group ii metabotropic glutamate receptors
|
|
AU2018265584B2
(en)
|
2017-05-12 |
2023-09-28 |
Ludwig-Maximilians-Universität München |
Phenyl-heterocycle-phenyl derivatives for use in the treatment or prevention of melanoma
|
|
JOP20190259A1
(ar)
|
2017-05-31 |
2019-10-31 |
Amgen Inc |
بروتينات ربط مولد ضد مضادة لـ jagged1
|
|
US20190062428A1
(en)
|
2017-06-19 |
2019-02-28 |
Surface Oncology, Inc. |
Combination of anti-cd47 antibodies and cell death-inducing agents, and uses thereof
|
|
EP3642239A1
(en)
|
2017-06-20 |
2020-04-29 |
Amgen Inc. |
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (gipr) in combination with glp-1 agonists
|
|
CN118812712A
(zh)
|
2017-07-11 |
2024-10-22 |
指南针制药有限责任公司 |
结合人cd137的激动剂抗体及其用途
|
|
KR102664604B1
(ko)
|
2017-07-14 |
2024-05-14 |
에프. 호프만-라 로슈 아게 |
이환형 케톤 화합물 및 이의 사용 방법
|
|
JP2020528054A
(ja)
|
2017-07-19 |
2020-09-17 |
オークランド ユニサービシズ リミテッド |
サイトカインモジュレーション
|
|
EP3665202A1
(en)
|
2017-08-09 |
2020-06-17 |
Massachusetts Institute Of Technology |
Albumin binding peptide conjugates and methods thereof
|
|
CA3073537A1
(en)
|
2017-08-22 |
2019-02-28 |
Sanabio, Llc |
Soluble interferon receptors and uses thereof
|
|
CN111148533A
(zh)
|
2017-09-19 |
2020-05-12 |
麻省理工学院 |
用于嵌合抗原受体t细胞疗法的组合物及其用途
|
|
JP2020537506A
(ja)
|
2017-10-04 |
2020-12-24 |
アムジエン・インコーポレーテツド |
トランスサイレチン免疫グロブリン融合物
|
|
KR20200070297A
(ko)
|
2017-10-11 |
2020-06-17 |
에프. 호프만-라 로슈 아게 |
Rip1 키나아제 억제제로서 사용하기 위한 이환형 화합물
|
|
WO2019078344A1
(ja)
|
2017-10-20 |
2019-04-25 |
学校法人兵庫医科大学 |
抗ｉｌ－６受容体抗体を含有する術後の癒着を抑制するための医薬組成物
|
|
MA50536A
(fr)
|
2017-10-30 |
2020-09-09 |
Enterin Inc |
Nouvelles formes solides de squalamine et procédés pour les produire
|
|
RU2020115915A
(ru)
|
2017-10-31 |
2021-12-01 |
Ф. Хоффманн-Ля Рош Аг |
Бициклические сульфоны и сульфоксиды и способы их применения
|
|
US11718679B2
(en)
|
2017-10-31 |
2023-08-08 |
Compass Therapeutics Llc |
CD137 antibodies and PD-1 antagonists and uses thereof
|
|
US11851497B2
(en)
|
2017-11-20 |
2023-12-26 |
Compass Therapeutics Llc |
CD137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
|
WO2019110139A1
(en)
|
2017-12-05 |
2019-06-13 |
Eth Zurich |
New compounds for use as a therapeutically active substance and in particular for use in the treatment of tumors
|
|
AU2018383679A1
(en)
|
2017-12-11 |
2020-05-07 |
Amgen Inc. |
Continuous manufacturing process for bispecific antibody products
|
|
KR102263812B1
(ko)
|
2017-12-14 |
2021-06-14 |
에이비엘바이오 주식회사 |
a-syn/IGF1R에 대한 이중 특이 항체 및 그 용도
|
|
EP3727447A1
(en)
|
2017-12-19 |
2020-10-28 |
Massachusetts Institute of Technology |
Antigen-adjuvant coupling reagents and methods of use
|
|
US11667713B2
(en)
|
2017-12-28 |
2023-06-06 |
Chugai Seiyaku Kabushiki Kaisha |
Cytotoxicity-inducing therapeutic agent
|
|
UY38041A
(es)
|
2017-12-29 |
2019-06-28 |
Amgen Inc |
Construcción de anticuerpo biespecífico dirigida a muc17 y cd3
|
|
WO2019151418A1
(ja)
|
2018-01-31 |
2019-08-08 |
元一 加藤 |
Ｉｌ－６阻害剤を含有する喘息の治療剤
|
|
RU2758378C1
(ru)
|
2018-02-09 |
2021-10-28 |
Галдерма Холдинг СА |
Немолизумаб в лечении атопического дерматита с экскориацией от умеренной до тяжелой
|
|
WO2019164778A1
(en)
|
2018-02-20 |
2019-08-29 |
Genentech, Inc. |
Process for preparing 1-arylsulfonyl-pyrrolidine-2-carboxamide transient receptor potential channel antagonist compounds and crystalline forms thereof
|
|
CN112041313A
(zh)
|
2018-02-26 |
2020-12-04 |
基因泰克公司 |
吡啶-磺酰胺化合物及其针对疼痛和相关疾患的用途
|
|
BR112020018480B1
(pt)
|
2018-03-14 |
2022-09-27 |
Surface Oncology, Inc |
Usos de anticorpos que se ligam a cd39 no tratamento de câncer
|
|
US10710994B2
(en)
|
2018-03-19 |
2020-07-14 |
Genentech, Inc. |
Oxadiazole transient receptor potential channel inhibitors
|
|
CN112512571A
(zh)
|
2018-03-22 |
2021-03-16 |
表面肿瘤学公司 |
抗il-27抗体及其用途
|
|
EP3774879A1
(en)
|
2018-03-30 |
2021-02-17 |
Amgen Inc. |
C-terminal antibody variants
|
|
CN111936494A
(zh)
|
2018-03-30 |
2020-11-13 |
豪夫迈·罗氏有限公司 |
作为钠通道抑制剂的取代的氢-吡啶并-吖嗪
|
|
US20210022978A1
(en)
|
2018-04-06 |
2021-01-28 |
Zilentin AG |
Bumetanide derivatives for the therapy of hyperhidrosis
|
|
WO2019193161A1
(en)
|
2018-04-06 |
2019-10-10 |
Universität Wien |
Bumetanide derivatives for the therapy of stroke and other neurological diseases/disorders involving nkccs
|
|
MX2020010659A
(es)
|
2018-04-09 |
2020-10-28 |
Amgen Inc |
Proteinas de fusion del factor de diferenciacion de crecimiento 15.
|
|
WO2019200357A1
(en)
|
2018-04-12 |
2019-10-17 |
Surface Oncology, Inc. |
Biomarker for cd47 targeting therapeutics and uses therefor
|
|
AU2019255370B2
(en)
|
2018-04-19 |
2023-11-02 |
Checkmate Pharmaceuticals, Inc. |
Synthetic RIG-I-like receptor agonists
|
|
EP3781571B1
(en)
|
2018-04-20 |
2024-01-17 |
F. Hoffmann-La Roche AG |
N-[4-oxo-2,3-dihydro-pyrido[3,2-b][1,4]oxazepin-3-yl]-5,6-dihydro-4h-pyrrolo[1,2-b]pyrazole-2-carboxamide derivatives and related compounds as rip1 kinase inhibitors for treating e.g. irritable bowel syndrome (ibs)
|
|
WO2019207051A1
(en)
|
2018-04-25 |
2019-10-31 |
Università Degli Studi Di Torino |
Medical use of combinations of non-natural semaphorins 3 and antimetabolites
|
|
WO2019226658A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Multispecific antigen-binding compositions and methods of use
|
|
CA3099308A1
(en)
|
2018-05-21 |
2019-11-28 |
Compass Therapeutics Llc |
Compositions and methods for enhancing the killing of target cells by nk cells
|
|
TW202003490A
(zh)
|
2018-05-22 |
2020-01-16 |
瑞士商赫孚孟拉羅股份公司 |
治療性化合物及其使用方法
|
|
WO2019225777A1
(ko)
|
2018-05-23 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-ror1 항체 및 그 용도
|
|
WO2019225787A1
(ko)
|
2018-05-24 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-b7-h3 항체 및 그 용도
|
|
WO2020011938A1
(en)
|
2018-07-11 |
2020-01-16 |
Medizinische Universität Wien |
Glucocorticoids for the topical treatment of autoimmune gastritis
|
|
US20220275043A1
(en)
|
2018-07-17 |
2022-09-01 |
Massachusetts Institute Of Technology |
Soluble multimeric immunoglobulin-scaffold based fusion proteins and uses thereof
|
|
WO2020033925A2
(en)
|
2018-08-09 |
2020-02-13 |
Compass Therapeutics Llc |
Antibodies that bind cd277 and uses thereof
|
|
EP3833443A1
(en)
|
2018-08-09 |
2021-06-16 |
Compass Therapeutics LLC |
Antigen binding agents that bind cd277 and uses thereof
|
|
WO2020033926A2
(en)
|
2018-08-09 |
2020-02-13 |
Compass Therapeutics Llc |
Antibodies that bind cd277 and uses thereof
|
|
JP2021535140A
(ja)
|
2018-08-28 |
2021-12-16 |
アンブルックス, インコーポレイテッドAmbrx, Inc. |
抗ｃｄ３抗体葉酸生物複合体およびその使用
|
|
TW202024023A
(zh)
|
2018-09-03 |
2020-07-01 |
瑞士商赫孚孟拉羅股份公司 |
治療性化合物及其使用方法
|
|
JP7441826B2
(ja)
|
2018-09-11 |
2024-03-01 |
アンブルックス，インコーポレイテッド |
インターロイキン－２ポリペプチド抱合物およびその使用
|
|
WO2020053808A1
(en)
|
2018-09-12 |
2020-03-19 |
Georg Dewald |
Method of diagnosing vasoregulatory disorders
|
|
JP7557882B2
(ja)
|
2018-09-28 |
2024-09-30 |
マサチューセッツ インスティテュート オブ テクノロジー |
コラーゲンに局在化される免疫調節分子およびその方法
|
|
CA3114802A1
(en)
|
2018-10-11 |
2020-04-16 |
Amgen Inc. |
Downstream processing of bispecific antibody constructs
|
|
EP3867265A1
(en)
|
2018-10-19 |
2021-08-25 |
Ambrx, Inc. |
Interleukin-10 polypeptide conjugates, dimers thereof, and their uses
|
|
EP3898614A1
(en)
|
2018-12-17 |
2021-10-27 |
Tolremo Therapeutics AG |
Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment, amelioration or prevention of cancer
|
|
BR112021013096A2
(pt)
|
2019-01-04 |
2022-04-19 |
Resolve Therapeutics, Llc |
Tratamento de doença de sjögren com proteínas de fusão de nuclease
|
|
EP3908586B1
(en)
|
2019-01-11 |
2022-12-21 |
F. Hoffmann-La Roche AG |
Bicyclic pyrrolotriazolr ketone compounds and methods of use thereof
|
|
US11680105B2
(en)
|
2019-01-17 |
2023-06-20 |
Regents Of The University Of Minnesota |
Antibody fragments for detecting cancer and methods of use
|
|
US11235032B2
(en)
|
2019-01-23 |
2022-02-01 |
Massachusetts Institute Of Technology |
Combination immunotherapy dosing regimen for immune checkpoint blockade
|
|
US11236157B2
(en)
|
2019-01-28 |
2022-02-01 |
Galderma Holding SA |
Treatment of skin lesions and pruritus in prurigo nodularis patients
|
|
AU2020223031B2
(en)
|
2019-02-12 |
2024-08-29 |
Ambrx, Inc. |
Compositions containing, methods and uses of antibody-TLR agonist conjugates
|
|
EP3941511A2
(en)
|
2019-03-20 |
2022-01-26 |
Massachusetts Institute of Technology |
Uses of amphiphiles in immune cell therapy and compositions therefor
|
|
BR112021017702A2
(pt)
|
2019-03-29 |
2021-11-16 |
Chugai Pharmaceutical Co Ltd |
Inibidor contendo anticorpo anti-receptor de il-6 para inibição de deterioração da função bhe
|
|
CA3135694A1
(en)
|
2019-04-17 |
2020-10-22 |
Hiroshima University |
Therapeutic agent for urological cancer which is characterized by being administered with il-6 inhibitor and ccr2 inhibitor in combination
|
|
JPWO2020241816A1
(da)
|
2019-05-31 |
2020-12-03 |
|
|
|
CA3142676A1
(en)
|
2019-06-05 |
2020-12-10 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody cleavage site binding molecule
|
|
KR102486064B1
(ko)
|
2019-06-10 |
2023-01-06 |
추가이 세이야쿠 가부시키가이샤 |
사이토카인 저해제와 조합하여 사용하기 위한 항t세포 항원 결합 분자
|
|
CA3137494A1
(en)
|
2019-06-13 |
2020-12-17 |
Amgen Inc. |
Automated biomass-based perfusion control in the manufacturing of biologics
|
|
EP3990491A1
(en)
|
2019-06-26 |
2022-05-04 |
Massachusetts Institute of Technology |
Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
|
|
AU2020310851A1
(en)
|
2019-07-08 |
2021-12-09 |
Amgen Inc. |
Multispecific transthyretin immunoglobulin fusions
|
|
SG11202112307YA
(en)
|
2019-07-10 |
2021-12-30 |
Chugai Pharmaceutical Co Ltd |
Claudin-6 binding molecules and uses thereof
|
|
AU2020323901A1
(en)
|
2019-07-26 |
2022-02-24 |
Amgen Inc. |
Anti-IL13 antigen binding proteins
|
|
MX2022001732A
(es)
|
2019-08-12 |
2022-05-06 |
Purinomia Biotech Inc |
Metodos y composiciones para promover y potenciar la respuesta inmunitaria mediada por linfocitos t dirigida a la adcc de las celulas con expresion de cd39.
|
|
CA3150441A1
(en)
|
2019-08-13 |
2021-02-18 |
Amgen Inc. |
Interleukin-2 muteins for the expansion of t-regulatory cells
|
|
MX2022003005A
(es)
|
2019-09-16 |
2022-04-07 |
Surface Oncology Inc |
Composiciones y metodos de anticuerpos anti-cd39.
|
|
CA3151078A1
(en)
|
2019-09-25 |
2021-04-01 |
Surface Oncology, Inc. |
Anti-il-27 antibodies and uses thereof
|
|
MX2022003617A
(es)
|
2019-10-02 |
2022-05-30 |
Tolremo Therapeutics Ag |
Derivados heterociclicos, composiciones farmaceuticas y su uso en el tratamiento o mejora del cancer.
|
|
WO2021064141A1
(en)
|
2019-10-02 |
2021-04-08 |
Tolremo Therapeutics Ag |
Inhibitors of dual specificity tyrosine phosphorylation regulated kinase 1b
|
|
TWI745114B
(zh)
|
2019-10-11 |
2021-11-01 |
日商中外製藥股份有限公司 |
用於後天性血友病a之預防及/或治療之醫藥組成物、及包含該醫藥組成物之製品
|
|
CA3157896A1
(en)
|
2019-10-16 |
2021-04-22 |
Cemm - Forschungszentrum Fur Molekulare Medizin Gmbh |
Oxazole and thioazole-type cullin ring ubiquitin ligase compounds and uses thereof
|
|
WO2021074418A1
(en)
|
2019-10-16 |
2021-04-22 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Carbazole-type cullin ring ubiquitin ligase compounds and uses thereof
|
|
WO2021081353A1
(en)
|
2019-10-23 |
2021-04-29 |
Checkmate Pharmaceuticals, Inc. |
Synthetic rig-i-like receptor agonists
|
|
WO2021080682A1
(en)
|
2019-10-24 |
2021-04-29 |
Massachusetts Institute Of Technology |
Monoclonal antibodies that bind human cd161 and uses thereof
|
|
JP2022554187A
(ja)
|
2019-10-24 |
2022-12-28 |
ミノトール セラピューティクス インコーポレイテッド |
キメラサイトカイン改変抗体およびその使用方法
|
|
JP2023501989A
(ja)
|
2019-11-13 |
2023-01-20 |
ジェネンテック， インコーポレイテッド |
治療用化合物および使用方法
|
|
EP4058485A1
(en)
|
2019-11-13 |
2022-09-21 |
Amgen Inc. |
Method for reduced aggregate formation in downstream processing of bispecific antigen-binding molecules
|
|
AU2020386151B2
(en)
|
2019-11-19 |
2023-09-21 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Novel compounds for the diagnosis, treatment and prevention of diseases associated with the aggregation of alpha-synuclein
|
|
BR112022011949A2
(pt)
|
2019-12-17 |
2022-11-22 |
Amgen Inc |
Dupla de interleucina-2/agonista do receptor tnf para uso em terapia
|
|
IL294330A
(en)
|
2020-01-06 |
2022-08-01 |
Vaccinex Inc |
Anti-ccr8 antibodies and their uses
|
|
WO2021173889A1
(en)
|
2020-02-26 |
2021-09-02 |
Ambrx, Inc. |
Uses of anti-cd3 antibody folate bioconjugates
|
|
CN115243726A
(zh)
|
2020-03-11 |
2022-10-25 |
北京泰德制药股份有限公司 |
白介素-2多肽偶联物及其使用方法
|
|
IL296601A
(en)
|
2020-03-19 |
2022-11-01 |
Amgen Inc |
Antibodies against mucin 17 and their uses
|
|
JP2023106635A
(ja)
|
2020-04-17 |
2023-08-02 |
中外製薬株式会社 |
二重特異性抗原結合分子ならびに、それに関連する組成物、組成物の製造のための使用、キット、および方法
|
|
WO2021221783A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
|
US20210338833A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Chimeric antigen receptor-targeting ligands and uses thereof
|
|
EP4161520A1
(en)
|
2020-06-05 |
2023-04-12 |
The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone |
Acvr1 (alk2) receptor inhibition to treat neurological diseases
|
|
GB202101299D0
(en)
|
2020-06-09 |
2021-03-17 |
Avacta Life Sciences Ltd |
Diagnostic polypetides and methods
|
|
IL299127A
(en)
|
2020-06-19 |
2023-02-01 |
Chugai Pharmaceutical Co Ltd |
Anti-T cell antigen binding molecule for use in combination with an angiogenesis inhibitor
|
|
US20230226057A1
(en)
|
2020-06-25 |
2023-07-20 |
Tolremo Therapeutics Ag |
Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment, amelioration or prevention of fibrotic disease
|
|
WO2022006153A1
(en)
|
2020-06-29 |
2022-01-06 |
Resolve Therapeutics, Llc |
Treatment of sjogren's syndrome with nuclease fusion proteins
|
|
EP3939578A1
(en)
|
2020-07-13 |
2022-01-19 |
Novaremed Ltd. |
Compounds for treatment or prevention of an infection resulting from a coronavirus and/or a coronavirus-induced disease
|
|
US11787775B2
(en)
|
2020-07-24 |
2023-10-17 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
WO2022023292A2
(en)
|
2020-07-31 |
2022-02-03 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Corona virus spike protein-targeting antibodies and use thereof
|
|
MX2023001120A
(es)
|
2020-07-31 |
2023-02-22 |
Chugai Pharmaceutical Co Ltd |
Composicion farmaceutica que comprende una celula que expresa un receptor quimerico.
|
|
WO2022040596A1
(en)
|
2020-08-20 |
2022-02-24 |
Ambrx, Inc. |
Antibody-tlr agonist conjugates, methods and uses thereof
|
|
EP3964497A1
(en)
|
2020-09-04 |
2022-03-09 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Substituted vicinal diamine compounds and their use in the treatment, amelioration or prevention of pain
|
|
CR20230183A
(es)
|
2020-10-02 |
2023-06-14 |
Genentech Inc |
Proceso para la preparación de compuestos de biheteroarilo y formas cristalinas de estos
|
|
WO2022087274A1
(en)
|
2020-10-21 |
2022-04-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibodies that neutralize type-i interferon (ifn) activity
|
|
EP4240768A2
(en)
|
2020-11-06 |
2023-09-13 |
Amgen Inc. |
Multitargeting bispecific antigen-binding molecules of increased selectivity
|
|
AU2022224636A1
(en)
|
2021-02-19 |
2023-09-07 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Single domain antibodies that neutralize sars-cov-2
|
|
EP4306127A1
(en)
|
2021-03-12 |
2024-01-17 |
Chugai Seiyaku Kabushiki Kaisha |
Pharmaceutical composition for treatment or prevention of myasthenia gravis
|
|
EP4313163A1
(en)
|
2021-04-03 |
2024-02-07 |
Ambrx, Inc. |
Anti-her2 antibody-drug conjugates and uses thereof
|
|
BR112023020538A2
(pt)
|
2021-04-07 |
2024-01-23 |
Tolremo Therapeutics Ag |
Derivados heterocíclicos, composições farmacêuticas e seus usos no tratamento ou na melhoria de câncer
|
|
JP2024517759A
(ja)
|
2021-04-28 |
2024-04-23 |
ミノトール セラピューティクス インコーポレイテッド |
ヒト化キメラウシ抗体および使用方法
|
|
IL307672A
(en)
|
2021-05-06 |
2023-12-01 |
Amgen Res Munich Gmbh |
CD20 and CD22 targeting antigen-binding molecules for use in proliferative diseases
|
|
WO2022236134A1
(en)
|
2021-05-07 |
2022-11-10 |
Surface Oncology, Inc. |
Anti-il-27 antibodies and uses thereof
|
|
WO2022241465A1
(en)
|
2021-05-14 |
2022-11-17 |
Claris Biotherapeutics, Inc. |
Compositions of growth factor for the treatment of eye disease
|
|
WO2023028056A1
(en)
|
2021-08-24 |
2023-03-02 |
Genentech, Inc. |
3-amino piperidyl sodium channel inhibitors
|
|
WO2023028077A1
(en)
|
2021-08-24 |
2023-03-02 |
Genentech, Inc. |
Sodium channel inhibitors and methods of designing same
|
|
WO2023031770A1
(en)
|
2021-08-30 |
2023-03-09 |
Galderma Holding SA |
Treatments for atopic dermatitis
|
|
EP4396228A1
(en)
|
2021-09-03 |
2024-07-10 |
University of Bern |
Compositions and methods for treating long qt syndrome
|
|
WO2023053282A1
(ja)
|
2021-09-29 |
2023-04-06 |
中外製薬株式会社 |
がんの治療に用いるための細胞傷害誘導治療剤
|
|
TW202334221A
(zh)
|
2021-11-03 |
2023-09-01 |
德商安富美德有限公司 |
雙特異性cd16a結合劑
|
|
MX2024005397A
(es)
|
2021-11-03 |
2024-05-23 |
Affimed Gmbh |
Agentes de union a cd16a biespecificos.
|
|
US12110276B2
(en)
|
2021-11-24 |
2024-10-08 |
Genentech, Inc. |
Pyrazolo compounds and methods of use thereof
|
|
US20230364031A1
(en)
|
2022-04-19 |
2023-11-16 |
Garth Cooper |
Treatment of brain copper disorders
|
|
WO2023203172A1
(en)
|
2022-04-20 |
2023-10-26 |
Proxygen Gmbh |
Heterocyclic cullin ring ubiquitin ligase compounds and uses thereof
|
|
WO2023218027A1
(en)
|
2022-05-12 |
2023-11-16 |
Amgen Research (Munich) Gmbh |
Multichain multitargeting bispecific antigen-binding molecules of increased selectivity
|
|
US20240026001A1
(en)
|
2022-05-25 |
2024-01-25 |
Surface Oncology, Inc. |
Use of anti-il-27 antibodies
|
|
US20240025987A1
(en)
|
2022-05-25 |
2024-01-25 |
Surface Oncology, Inc. |
Use of anti-il-27 antibodies
|
|
WO2024050526A1
(en)
|
2022-09-02 |
2024-03-07 |
Biomarin Pharmaceutical Inc. |
Compositions and methods for treating long qt syndrome
|
|
US20240141050A1
(en)
|
2022-09-02 |
2024-05-02 |
Galderma Holding S.A. |
Treatments for prurigo nodularis
|
|
TW202421650A
(zh)
|
2022-09-14 |
2024-06-01 |
美商安進公司 |
雙特異性分子穩定組成物
|
|
WO2024076995A1
(en)
|
2022-10-03 |
2024-04-11 |
Insigna Inc. |
Compositions for non-surgical prevention of boar taint and aggressive behavior
|
|
WO2024121796A1
(en)
|
2022-12-07 |
2024-06-13 |
Fondazione Matilde Tettamanti E Menotti De Marchi Onlus |
Methods for generating genetically modified cytokine induced killer (cik) cells
|