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DK2311818T3 - Kombination af en 5-phenylthiazolforbindelse som PI3-kinasehæmmer med et antiinflammatorisk, bronchodilatorisk eller antihistaminisk medikament - Google Patents

Kombination af en 5-phenylthiazolforbindelse som PI3-kinasehæmmer med et antiinflammatorisk, bronchodilatorisk eller antihistaminisk medikament

Info

Publication number
DK2311818T3
DK2311818T3 DK10174528.9T DK10174528T DK2311818T3 DK 2311818 T3 DK2311818 T3 DK 2311818T3 DK 10174528 T DK10174528 T DK 10174528T DK 2311818 T3 DK2311818 T3 DK 2311818T3
Authority
DK
Denmark
Prior art keywords
bronchodilatory
inflammatory
combination
kinase inhibitor
antihistaminic drug
Prior art date
Application number
DK10174528.9T
Other languages
English (en)
Inventor
Ian Bruce
Catherine Leblanc
Clive Mccarthy
Lewis Whitehead
Nicola Elaine Press
Graham Charles Bloomfield
Judy Hayler
Louise Kirman
Mrinalini Sachin Oza
Lena Shukla
Peter Finan
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27767104&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2311818(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0204765A external-priority patent/GB0204765D0/en
Priority claimed from GB0229626A external-priority patent/GB0229626D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK2311818T3 publication Critical patent/DK2311818T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
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    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
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    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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DK10174528.9T 2002-02-28 2003-02-27 Kombination af en 5-phenylthiazolforbindelse som PI3-kinasehæmmer med et antiinflammatorisk, bronchodilatorisk eller antihistaminisk medikament DK2311818T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0204765A GB0204765D0 (en) 2002-02-28 2002-02-28 Organic compounds
GB0229626A GB0229626D0 (en) 2002-12-19 2002-12-19 Organic compounds
EP03709730A EP1480962B1 (en) 2002-02-28 2003-02-27 5-phenylthiazole derivatives and use as pi3 kinase inhibitors

Publications (1)

Publication Number Publication Date
DK2311818T3 true DK2311818T3 (da) 2013-05-06

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Family Applications (2)

Application Number Title Priority Date Filing Date
DK03709730.0T DK1480962T3 (da) 2002-02-28 2003-02-27 5-Phenylthiazol-derivater og deres anvendelse som P1-3-kinaseinhibitorer
DK10174528.9T DK2311818T3 (da) 2002-02-28 2003-02-27 Kombination af en 5-phenylthiazolforbindelse som PI3-kinasehæmmer med et antiinflammatorisk, bronchodilatorisk eller antihistaminisk medikament

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK03709730.0T DK1480962T3 (da) 2002-02-28 2003-02-27 5-Phenylthiazol-derivater og deres anvendelse som P1-3-kinaseinhibitorer

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US (2) US7687637B2 (da)
EP (1) EP1480962B1 (da)
JP (2) JP4408701B2 (da)
KR (1) KR100688370B1 (da)
CN (1) CN100548996C (da)
AR (1) AR038703A1 (da)
AT (1) ATE521598T1 (da)
AU (1) AU2003214080A1 (da)
BR (1) BR0308030A (da)
CA (1) CA2477601C (da)
CO (1) CO5611131A2 (da)
CY (2) CY1112084T1 (da)
DK (2) DK1480962T3 (da)
EC (2) ECSP045253A (da)
ES (2) ES2405816T3 (da)
HK (1) HK1071363A1 (da)
IL (2) IL163691A0 (da)
MX (1) MXPA04008362A (da)
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NO (1) NO329175B1 (da)
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PE (1) PE20030968A1 (da)
PL (2) PL219449B1 (da)
PT (2) PT1480962E (da)
RU (2) RU2436780C2 (da)
SI (1) SI1480962T1 (da)
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WO (1) WO2003072557A1 (da)

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IL142094A0 (en) 1998-09-29 2002-03-10 Gamida Cell Ltd Methods of controlling proliferation and differentiation of stem and progenitor cells
IL152904A0 (en) 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
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