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DE69232837D1 - Oxycodonhaltiges Arzneimittel mit verzögerter Wirkstoffabgabe - Google Patents

Oxycodonhaltiges Arzneimittel mit verzögerter Wirkstoffabgabe

Info

Publication number
DE69232837D1
DE69232837D1 DE69232837T DE69232837T DE69232837D1 DE 69232837 D1 DE69232837 D1 DE 69232837D1 DE 69232837 T DE69232837 T DE 69232837T DE 69232837 T DE69232837 T DE 69232837T DE 69232837 D1 DE69232837 D1 DE 69232837D1
Authority
DE
Germany
Prior art keywords
oxycodone
mean
hrs
admin
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69232837T
Other languages
English (en)
Other versions
DE69232837T3 (de
DE69232837T2 (de
Inventor
Benjamin Oshlack
John Joseph Minogue
Mark Chasin
Robert Francis Kaiko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mundipharma GmbH
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25178688&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69232837(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Application granted granted Critical
Publication of DE69232837D1 publication Critical patent/DE69232837D1/de
Publication of DE69232837T2 publication Critical patent/DE69232837T2/de
Anticipated expiration legal-status Critical
Publication of DE69232837T3 publication Critical patent/DE69232837T3/de
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Measuring Fluid Pressure (AREA)
  • Polyethers (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69232837.8T 1991-11-27 1992-11-25 Oxycodonhaltiges Arzneimittel mit verzögerter Wirkstoffabgabe Expired - Lifetime DE69232837T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/800,549 US5266331A (en) 1991-11-27 1991-11-27 Controlled release oxycodone compositions
US800549 1991-11-27
EP96102992.3A EP0722730B2 (de) 1991-11-27 1992-11-25 Oxycodonhaltiges Arzneimittel mit verzögerter Wirkstoffabgabe

Publications (3)

Publication Number Publication Date
DE69232837D1 true DE69232837D1 (de) 2002-12-05
DE69232837T2 DE69232837T2 (de) 2003-06-18
DE69232837T3 DE69232837T3 (de) 2014-01-02

Family

ID=25178688

Family Applications (10)

Application Number Title Priority Date Filing Date
DE69233699T Expired - Lifetime DE69233699T2 (de) 1991-11-27 1992-11-25 Oxycodonzusammensetzungen mit kontrollierter Freisetzung
DE69233328T Expired - Lifetime DE69233328T3 (de) 1991-11-27 1992-11-25 Oxycodonhaltige Arzneizusammensetzungen mit verzögerter Wirkstoffabgabe
DE69233326T Expired - Lifetime DE69233326T2 (de) 1991-11-27 1992-11-25 Oxycodonhaltige Zubereitungen mit gesteuerter Wirkstoffabgabe
DE9219234U Expired - Lifetime DE9219234U1 (de) 1991-11-27 1992-11-25 Oxycodon-Zusammensetzung mit kontrollierter Freisetzung
DE69233691T Expired - Lifetime DE69233691T2 (de) 1991-11-27 1992-11-25 Oxycodonzusammensetzungen mit kontrollierter Freisetzung
DE69232837.8T Expired - Lifetime DE69232837T3 (de) 1991-11-27 1992-11-25 Oxycodonhaltiges Arzneimittel mit verzögerter Wirkstoffabgabe
DE69233327T Expired - Lifetime DE69233327T2 (de) 1991-11-27 1992-11-25 Oxycodonhaltige Arzneizusammensetzungen mit verzögerter Wirkstoffabgabe
DE69233640T Expired - Lifetime DE69233640T2 (de) 1991-11-27 1992-11-25 Oxycodonsalzzusammensetzungen mit kontrollierter Freisetzung
DE69214802T Expired - Lifetime DE69214802T2 (de) 1991-11-27 1992-11-25 Oxycodon-zusammensetzungen mit kontrollierter freisetzung
DE69233778T Expired - Lifetime DE69233778D1 (de) 1991-11-27 1992-11-25 Oxycodonzusammensetzungen mit kontrollierter Freisetzung

Family Applications Before (5)

Application Number Title Priority Date Filing Date
DE69233699T Expired - Lifetime DE69233699T2 (de) 1991-11-27 1992-11-25 Oxycodonzusammensetzungen mit kontrollierter Freisetzung
DE69233328T Expired - Lifetime DE69233328T3 (de) 1991-11-27 1992-11-25 Oxycodonhaltige Arzneizusammensetzungen mit verzögerter Wirkstoffabgabe
DE69233326T Expired - Lifetime DE69233326T2 (de) 1991-11-27 1992-11-25 Oxycodonhaltige Zubereitungen mit gesteuerter Wirkstoffabgabe
DE9219234U Expired - Lifetime DE9219234U1 (de) 1991-11-27 1992-11-25 Oxycodon-Zusammensetzung mit kontrollierter Freisetzung
DE69233691T Expired - Lifetime DE69233691T2 (de) 1991-11-27 1992-11-25 Oxycodonzusammensetzungen mit kontrollierter Freisetzung

Family Applications After (4)

Application Number Title Priority Date Filing Date
DE69233327T Expired - Lifetime DE69233327T2 (de) 1991-11-27 1992-11-25 Oxycodonhaltige Arzneizusammensetzungen mit verzögerter Wirkstoffabgabe
DE69233640T Expired - Lifetime DE69233640T2 (de) 1991-11-27 1992-11-25 Oxycodonsalzzusammensetzungen mit kontrollierter Freisetzung
DE69214802T Expired - Lifetime DE69214802T2 (de) 1991-11-27 1992-11-25 Oxycodon-zusammensetzungen mit kontrollierter freisetzung
DE69233778T Expired - Lifetime DE69233778D1 (de) 1991-11-27 1992-11-25 Oxycodonzusammensetzungen mit kontrollierter Freisetzung

Country Status (31)

Country Link
US (13) US5266331A (de)
EP (15) EP1502592B1 (de)
JP (2) JP3375960B2 (de)
KR (1) KR100280973B1 (de)
CN (2) CN1245958C (de)
AT (9) ATE261726T1 (de)
AU (1) AU657027B2 (de)
BG (1) BG61753B1 (de)
BR (1) BR9205498A (de)
CA (1) CA2098738C (de)
CZ (4) CZ286913B6 (de)
DE (10) DE69233699T2 (de)
DK (10) DK1438959T3 (de)
ES (9) ES2215983T3 (de)
FI (5) FI113152B (de)
GR (1) GR3022273T3 (de)
HK (6) HK1058474A1 (de)
HU (10) HU228058B1 (de)
IL (1) IL103909A (de)
MX (1) MX9302968A (de)
NO (6) NO307028B3 (de)
PH (1) PH31679A (de)
PL (2) PL172236B1 (de)
PT (8) PT722730E (de)
RO (1) RO115112B1 (de)
RS (3) RS50056B (de)
RU (1) RU2122411C1 (de)
SK (1) SK280295B6 (de)
WO (1) WO1993010765A1 (de)
YU (1) YU49495B (de)
ZA (1) ZA929227B (de)

Families Citing this family (297)

* Cited by examiner, † Cited by third party
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EP1438959B1 (de) 2007-04-25
CN1364458A (zh) 2002-08-21
HU0400226D0 (en) 2004-04-28
IL103909A0 (en) 1993-04-04
EP0722730B1 (de) 2002-10-30
ES2215983T3 (es) 2004-10-16
US20040096500A1 (en) 2004-05-20
CZ298499B6 (cs) 2007-10-17
JP3375960B2 (ja) 2003-02-10
DK1327446T4 (da) 2007-12-17
ATE332691T1 (de) 2006-08-15
DE69214802D1 (de) 1996-11-28
EP2106796A2 (de) 2009-10-07
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US20060165792A1 (en) 2006-07-27
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HU0400225D0 (en) 2004-04-28
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FI933330A (fi) 1993-07-23
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