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CY1107446T1 - Ανθελμινθικες συνθεσεις - Google Patents

Ανθελμινθικες συνθεσεις

Info

Publication number
CY1107446T1
CY1107446T1 CY20081100463T CY081100463T CY1107446T1 CY 1107446 T1 CY1107446 T1 CY 1107446T1 CY 20081100463 T CY20081100463 T CY 20081100463T CY 081100463 T CY081100463 T CY 081100463T CY 1107446 T1 CY1107446 T1 CY 1107446T1
Authority
CY
Cyprus
Prior art keywords
triclabendazole
solution
mixing
composition
anthelmintic compositions
Prior art date
Application number
CY20081100463T
Other languages
English (en)
Inventor
Manson Harvey Colin
Original Assignee
Merial Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19927212&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1107446(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merial Limited filed Critical Merial Limited
Publication of CY1107446T1 publication Critical patent/CY1107446T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Η εφεύρεση αναφέρεται σε μία νέα σύνθεση έχουσα το πλεονέκτημα ότι περιλαμβάνει τρικλαβενδαζόλη σε διάλυμα. Επί πλέον μπορεί να περιλαμβάνεται και ένα ακόμη ανθελμινθικό. Η σύνθεση παρασκευάζεται δι' αναμίξεως της αβαμεκτίνης και βενζυλικής αλκοόλης και αναμίξεως αυτών με τρικλαβενδαζόλη και βουτυλ διοξιτόλη. Εν συνεχεία το μίγμα θερμαίνεται για να διαλυθεί η δραστική ουσία και αφήνεται να ψυχθεί, οπότε το διάλυμα αραιώνεται στον τελικό όγκο με PEG 4000. Η παρούσα εφεύρεση υπερνικά τις δυσκολίες διαλύσεως της τρικλαβενδαζόλης και παρουσιάζει την τρικλαβενδαζόλη σε διάλυμα.
CY20081100463T 1999-04-14 2008-04-30 Ανθελμινθικες συνθεσεις CY1107446T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ335166A NZ335166A (en) 1999-04-14 1999-04-14 Anthelmintic composition containing triclabendazole in at least one solvent
EP00917514A EP1171124B2 (en) 1999-04-14 2000-04-14 Anthelmintic compositions

Publications (1)

Publication Number Publication Date
CY1107446T1 true CY1107446T1 (el) 2012-12-19

Family

ID=19927212

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100463T CY1107446T1 (el) 1999-04-14 2008-04-30 Ανθελμινθικες συνθεσεις

Country Status (16)

Country Link
US (1) US7638545B1 (el)
EP (1) EP1171124B2 (el)
AT (1) ATE386516T1 (el)
AU (1) AU760791B2 (el)
CA (1) CA2364742C (el)
CY (1) CY1107446T1 (el)
DE (1) DE60038106T3 (el)
DK (1) DK1171124T4 (el)
ES (1) ES2302691T5 (el)
HU (1) HU225620B1 (el)
NZ (1) NZ335166A (el)
PT (1) PT1171124E (el)
SI (1) SI1171124T2 (el)
SK (1) SK286363B6 (el)
WO (1) WO2000061068A2 (el)
ZA (1) ZA200108323B (el)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU733095B3 (en) * 1999-09-22 2001-05-03 Ashmont Holdings Limited Sheep pour on
US8067382B2 (en) * 2002-01-08 2011-11-29 Merial Limited Anthelmintic composition
CN1435176A (zh) * 2002-01-29 2003-08-13 王玉万 以表面活性剂为基础的含三氯苯哒唑的新制剂
GB2386066A (en) 2002-02-28 2003-09-10 Norbrook Lab Ltd Long-acting parasiticidal composition with improved bioavailability comprising a salicylanilide, a further anti-parasitic compound & a polymeric species
AU2002952597A0 (en) * 2002-11-11 2002-11-28 Schering-Plough Pty. Limited Topical parasiticide formulations and methods of treatment
GB2403408B (en) * 2003-07-03 2007-09-19 Michael Hilary Burke Process for preparing a stable anthelmintic suspension formulation
GB0316377D0 (en) 2003-07-12 2003-08-13 Norbrook Lab Ltd Parasiticidal composition
ATE466578T1 (de) * 2004-02-03 2010-05-15 Wyeth Llc Wurmmittel
BRPI0520550B1 (pt) * 2005-09-15 2020-03-03 Merial, Inc Fórmulas anti-helmínticas
BRPI0506279B1 (pt) 2005-12-16 2018-01-09 Npa - Núcleo De Pesquisas Aplicadas Ltda Composição sinergística de antihelmínticos e endectocidas
NZ552040A (en) * 2006-12-13 2009-04-30 Bomac Research Ltd Veterinary formulation comprising an anthelmintic compound and glyceryl acetate
JP5513403B2 (ja) * 2007-11-26 2014-06-04 メリアル リミテッド 寄生虫を駆除するためのポア−オン処方物用の溶媒系
AU2013201461B2 (en) * 2007-11-26 2015-10-29 Boehringer Ingelheim Animal Health USA Inc. Solvent systems for pour-on formulations for combating parasites
AU2009245834B2 (en) 2008-10-08 2013-11-14 Zoetis Services Llc Benzimidazole anthelmintic compositions
AR081970A1 (es) 2010-06-24 2012-10-31 Intervet Int Bv Formulacion inyectable de una lactona macrociclica y levamisol, formulacion y uso veterinario
NZ627856A (en) 2010-12-07 2016-03-31 Merial Inc Topical combination formulations of macrocyclic lactones with synthetic pyrethroids
CN119031903A (zh) * 2022-05-19 2024-11-26 陶氏环球技术有限责任公司 基于peg的聚合物间复合物用于改善bcs ii类药物的增溶的用途

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2614841A1 (de) 1976-04-06 1977-10-20 Bayer Ag Neue pour-on-formulierungen von anthelmintika
CH634306A5 (de) 1977-04-12 1983-01-31 Ciba Geigy Ag Benzimidazolderivate, verfahren zu ihrer herstellung und anthelmintische mittel enthaltend diese verbindungen als wirkstoffe.
US4144352A (en) * 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
OA06863A (fr) 1980-08-04 1983-02-28 Merck & Co Inc Solubilisation de l'invermectine dans l'eau.
JPS57139012A (en) 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
GB2117638B (en) * 1982-03-16 1986-10-29 Wellcome Australia Pour-on formulation
AU563927B2 (en) * 1983-08-12 1987-07-30 Pitman-Moore Australia Limited Compositions
IE58016B1 (en) * 1983-08-12 1993-06-16 Ici Australia Ltd Pour-on formulation for the control of parasites
NZ209100A (en) 1983-08-22 1987-01-23 Ici Australia Ltd Topical compositions for control of endoparasites
AU3135884A (en) * 1983-08-22 1985-02-28 Ici Australia Limited Endoparasiticides with ketone carriers
NZ210505A (en) 1983-12-22 1988-06-30 Merck & Co Inc Parasiticidal compositions containing avermectin or milbemycin derivatives
US5169846A (en) 1989-10-12 1992-12-08 Crooks Michael J Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators
GB9115273D0 (en) 1991-07-15 1991-08-28 Pfizer Ltd Benzimidazole anthelmintics
GB9205368D0 (en) 1992-03-12 1992-04-22 Pfizer Ltd Benzimidozole anthelmintic agents
GB9302107D0 (en) * 1993-02-03 1993-03-24 Univ Court Of The University O Benzimidazole compositions
BR9406627A (pt) 1993-05-26 1996-02-06 Commw Scient Ind Res Org Composições antiparasiticas
NZ260018A (en) 1994-03-03 1995-10-26 Bomac Lab Ltd Benzimidazole compositions and anthelmintic compositions
KR100277287B1 (ko) * 1995-09-25 2001-01-15 맨슨 하비 콜린 거대환 락톤 구충제 조성물
US5861142A (en) † 1996-03-25 1999-01-19 Schick; Mary Pichler Method for promoting hair, nail, and skin keratinization
US6165987A (en) * 1996-07-30 2000-12-26 Harvey; Colin Manson Anthelmintic formulations
FR2755824B1 (fr) † 1996-11-19 1999-01-08 Virbac Sa Formulation galenique des benzimidazoles a usage topique, son procede de preparation et ses utilisations
ZA981925B (en) 1997-03-21 1998-10-23 Biogenesis S A A long acting injectable parasiticidal composition and the process for its preparation
NZ329247A (en) 1997-11-20 2000-08-25 Bomac Lab Ltd Anthelmintic compositions containing solubilised benzimidazoles such as oxfendazole and a carrier including a pyrrolidone
US6340672B1 (en) 2000-02-16 2002-01-22 Phoenix Scientific, Inc. Parasiticidal formulation and a method of making this formulation

Also Published As

Publication number Publication date
CA2364742C (en) 2010-03-23
EP1171124B2 (en) 2010-10-27
NZ335166A (en) 2001-11-30
WO2000061068A2 (en) 2000-10-19
AU760791C (en) 2000-11-14
DE60038106T3 (de) 2011-06-01
DK1171124T3 (da) 2008-06-16
ES2302691T3 (es) 2008-08-01
WO2000061068A3 (en) 2001-01-11
CA2364742A1 (en) 2000-10-19
HUP0200735A3 (en) 2004-03-29
DE60038106T2 (de) 2009-01-29
AU760791B2 (en) 2003-05-22
EP1171124A4 (en) 2004-05-12
US7638545B1 (en) 2009-12-29
SI1171124T2 (sl) 2011-02-28
EP1171124B1 (en) 2008-02-20
DK1171124T4 (da) 2011-02-07
ES2302691T5 (es) 2011-03-16
EP1171124A2 (en) 2002-01-16
SI1171124T1 (sl) 2008-08-31
AU3847400A (en) 2000-11-14
ZA200108323B (en) 2002-06-26
SK14202001A3 (sk) 2002-05-09
DE60038106D1 (de) 2008-04-03
PT1171124E (pt) 2008-04-18
HUP0200735A2 (hu) 2002-07-29
ATE386516T1 (de) 2008-03-15
SK286363B6 (sk) 2008-08-05
HU225620B1 (en) 2007-05-02

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