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CN101322664A - 用于伤口辅助输送的晶状体注入腔尖端 - Google Patents

用于伤口辅助输送的晶状体注入腔尖端 Download PDF

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CN101322664A
CN101322664A CNA2008100917246A CN200810091724A CN101322664A CN 101322664 A CN101322664 A CN 101322664A CN A2008100917246 A CNA2008100917246 A CN A2008100917246A CN 200810091724 A CN200810091724 A CN 200810091724A CN 101322664 A CN101322664 A CN 101322664A
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CN101322664B (zh
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D·A·唐纳
K·F·芝亚
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Alcon Pharmaceuticals Ltd
Novartis AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1662—Instruments for inserting intraocular lenses into the eye
    • A61F2/1678—Instruments for inserting intraocular lenses into the eye with a separate cartridge or other lens setting part for storage of a lens, e.g. preloadable for shipping

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Abstract

一种用于IOL输送系统的盒被特定地设计用于帮助伤口辅助IOL输送。喷嘴的远尖端具有用于打开切口和支撑IOL的延伸篷盖。从远尖端的侧面侧向延伸的周边突出部、凸缘或止挡部提供有效深度限制，并且防止喷嘴完全插入切口中。另外，突出部为切口提供支撑以减小通过撕裂破坏伤口的趋势。

Description

用于伤口辅助输送的晶状体注入腔尖端
技术领域
本发明涉及眼内晶状体(IOLs)，尤其涉及用于将IOLs注入到眼中的盒。
背景技术
人眼的最简单功能在于通过经由被称为角膜的透明外部分透射和折射光，并且进一步依靠晶状体将图像聚焦在眼睛后面的视网膜上提供视觉。聚焦图像的质量取决于许多因素，包括眼睛的大小、形状和长度，以及角膜和晶状体的形状和透明度。
当创伤、年龄或疾病导致晶状体变得不太透明时，视觉由于可以透射到视网膜的光减少而退化。眼睛的晶状体的该缺陷在医学上被称为白内障。该状况的治疗是手术摘除晶状体和植入人造晶状体或IOL。
尽管早期IOLs由硬塑料，例如聚甲基丙烯酸甲酯(PMMA)制造，由硅树脂，软丙烯酸树脂和水凝胶制造的软的、可折叠的IOLs由于能够折叠或卷拢这些软晶状体并且通过更小切口插入它们而变得日益流行。卷拢或折叠晶状体的几种方法被使用。一种流行方法是注入盒，其折叠晶状体并且提供较小直径的腔，晶状体通常可以通过软尖端活塞被推入眼中。最常用的注入盒设计在美国专利No.4,681,102(Bartell)中被说明，并且包括裂口、纵向铰接盒。类似设计在美国专利Nos.5,494,484和5,499,987(Feingold)和5,616,148和5,620,450(Eagles等人)中被说明。为了试图避免美国专利No.4,681,102的权利要求，研究了几种固体盒，例如参见美国专利No.5,275,604(Rheinish等人)，5,653,715(Reich等人)和美国专利No.5,947,976(Van Noy等人)。
这些现有技术设备旨在通过较大(大约3.0mm或更大)切口将IOL注入到无晶状体眼的后房中。研发出允许通过小得多的切口，2.4mm和更小，执行完整外科操作的外科技术和IOLs。结果，外科医生开始研发伤口辅助IOL插入的方法，其中通过小切口输送IOL而不需要将盒尖端完全插入伤口中。在该类型的IOL输送中，伤口自身提供IOL通过其进入前房的通道。所以，伤口辅助IOL输送消除了需要足够大的切口以容纳盒尖端的外径，从而允许使用更小的切口。在本发明之前，这样的伤口辅助输送使用高度依赖于外科医生的熟练程度和信心的技术完成。
发明内容
本发明通过提供一种用于IOL输送系统的盒改进现有技术，所述盒包括在盒的远尖端的延伸蓬盖和提供插入深度限制和防止盒尖端完全插入的周边突出部、凸缘或止挡部，同时在折叠晶状体通过伤口时导引和控制所述晶状体的所述延伸蓬盖打开和支撑伤口。另外，所述突出部为切口提供支撑以减小通过撕裂破坏伤口的趋势。
因此本发明的目标是提供一种用于晶状体输送系统的盒，该盒具有在远尖端的延伸蓬盖。
本发明的进一步目标是提供一种用于晶状体输送系统的盒，该盒包含提供插入深度限制的周边突出部、凸缘或止挡部。
本发明的更进一步目标是提供一种用于晶状体输送系统的盒，该盒包含为切口提供支撑以减小通过撕裂破坏伤口的趋势的周边突出部、凸缘或止挡部。
参考附图以及附图和权利要求的以下描述将显而易见本发明的其他目标、特征和优点。
附图说明
图1是本发明的晶状体输送系统盒的放大顶视透视图。
图2是本发明的晶状体输送系统盒的远尖端的第一实施例的放大前视部分透视图。
图3是本发明的晶状体输送系统盒的远尖端的第一实施例的放大侧视正视图。
图4是本发明的晶状体输送系统盒的远尖端的第二实施例的放大前视部分透视图。
图5是本发明的晶状体输送系统盒的远尖端的第三实施例的放大前视正视图。
图6是插入眼中的切口中的晶状体输送系统盒的放大侧视正视图。
具体实施方式
在图1中最佳地可见，本发明的晶状体盒10通常包括主体12和喷嘴14。盒10可以由任何合适的热塑性塑料例如聚丙烯模制，并且热塑性塑料可以包含例如在美国专利No.5,716,364中公开的润滑增强剂，上述专利的全部内容被引用于此作为参考。喷嘴14可以与主体12形成一体。喷嘴14包括远尖端16。主体12包含腔孔或腔15。在使用前，IOL13初始定位在主体12的腔15内。
在图2-3中最佳地可见，远尖端16包括开口18、蓬盖20和周边突出部22。蓬盖20从远尖端16延伸并且用于在IOL 13插入前打开伤口。另外，蓬盖20的上部分21在伤口辅助输送期间为折叠IOL 13提供支撑。在图2和3所示的优选实施例中，蓬盖20完全包围开口18。在该实施例中，蓬盖20从在大约12点钟位置32的在大约1.5毫米至2.4毫米之间(优选大约1.9毫米)的其最大长度逐渐缩小以与在大约6点钟位置34的开口18齐平。在图4所示的第二实施例中，蓬盖20’从大约10点钟位置24到大约2点钟位置26仅仅部分包围开口18’。类似于蓬盖20，蓬盖20’从在位置27的在大约1.5毫米至2.4毫米之间(并且优选大约1.9毫米)的最大长度逐渐缩小以与在大约10点钟位置24和大约2点钟位置26的开口18’齐平。在图5所示的第三实施例中，蓬盖20”从大约9点钟位置28到大约3点钟位置30大致包围开口18”。在该实施例中，蓬盖20”也从在位置25的在大约1.5毫米至2.4毫米之间(并且优选大约1.9毫米)的最大长度逐渐缩小以与在大约9点钟位置28和大约3点钟位置30的开口18”齐平。
周边突出部22可以是适合于防止远尖端16完全进入切口的任何部件，例如凸缘或止挡部。周边突出部22从远尖端16的外壁36侧向地延伸，并且可以是完全包围喷嘴14的连续突出部。然而，周边突出部22可以不是连续的并且最优选地包括例如从远尖端16的外壁36的两侧侧向地延伸的多个突出部22。周边突出部22用作插入深度限制，并且防止远尖端16完全插入伤口入口中。周边突出部22的远端面23可以是方形的或倾斜大约18至26度之间(优选大约22度)的角。这样的倾斜将允许与眼睛的表面的更密切接触和提供更小的组织刺激，原因是盒10在使用中通常保持与眼睛52成一个角度，如图6中所示。蓬盖20和周边突出部22都可以与喷嘴14的远尖端16形成一体。
在图6中所示的操作期间，外科医生在眼睛52中制造切口50。将蓬盖20插入切口50中这样一个深度，即，使得突出部22接触眼睛52的表面并且防止进一步插入。当IOL 13移动通过开口18，通过切口50，并且插入眼睛52中时，蓬盖20的上部分21保持切口50打开并且支撑IOL 13。
尽管以上描述了本发明的某些实施例，这些描述是为了图解和解释而给出。可以在不脱离本发明的范围或精神的情况下采用以上公开的系统和方法的变化、改变、修改和变更。

Claims (15)

1.一种眼内晶状体注入盒，其包括：
a)主体，其具有内腔；
b)管状喷嘴，其具有外壁和开口，所述喷嘴从所述主体朝远端突出，所述开口流体连接到所述主体的所述内腔；
c)蓬盖，其从所述开口朝远侧突出；以及
d)至少一个周边突出部，其与所述开口邻近地从所述喷嘴的所述外壁侧向延伸。
2.根据权利要求1所述的眼内晶状体注入盒，其中所述蓬盖在大约10点钟位置至大约2点钟位置之间部分地围绕所述开口。
3.根据权利要求1所述的眼内晶状体注入盒，其中所述蓬盖在大约9点钟位置至大约3点钟位置之间部分地围绕所述开口。
4.根据权利要求1所述的眼内晶状体注入盒，其中所述蓬盖完全围绕所述开口。
5.根据权利要求1所述的眼内晶状体注入盒，其中所述周边突出部包括多个突出部。
6.根据权利要求1所述的眼内晶状体注入盒，其中所述周边突出部包括包围所述喷嘴的连续突出部。
7.根据权利要求1所述的眼内晶状体注入盒，其中所述周边突出部包括倾斜的远端面。
8.根据权利要求1所述的眼内晶状体注入盒，其中所述周边突出部包括凸缘。
9.根据权利要求1所述的眼内晶状体注入盒，其中所述周边突出部包括止挡部。
10.一种眼内晶状体注入盒，其包括：
a)主体，其具有内腔；
b)管状喷嘴，其具有外壁和开口，所述喷嘴从所述主体朝远侧突出，所述开口流体连接到所述主体的所述内腔；
c)蓬盖，其从所述开口朝远侧突出，所述蓬盖在大约9点钟位置至大约3点钟位置之间部分地围绕所述开口；以及
d)多个周边突出部，其与所述开口邻近地从所述喷嘴的所述外壁侧向延伸。
11.根据权利要求10所述的眼内晶状体注入盒，其中所述突出部包括倾斜远端面。
12.一种眼内晶状体注入盒，其包括：
a)主体，其具有内腔；
b)管状喷嘴，其具有外壁和开口，所述喷嘴从所述主体朝远侧突出，所述开口流体连接到所述主体的所述内腔；
c)蓬盖，其从所述开口朝远侧突出，所述蓬盖在大约10点钟位置至大约2点钟位置之间部分地围绕所述开口；以及
d)多个周边突出部，其与所述开口邻近地从所述喷嘴的所述外壁侧向延伸。
13.根据权利要求12所述的眼内晶状体注入盒，其中所述突出部包括倾斜的远端面。
14.一种将眼内晶状体输送到眼睛的方法，其包括以下步骤：
a)提供一种眼内晶状体注入盒，其具有主体；喷嘴；远尖端，所述远尖端具有开口和从所述开口朝远侧突出的蓬盖；和至少一个周边突出部；
b)在眼睛中制造切口；
c)将所述晶状体注入盒的所述蓬盖插入所述切口中；
d)使眼睛与所述周边突出部接触以防止所述远尖端进一步插入所述切口中；以及
e)通过所述切口将晶状体插入眼中。
15.根据权利要求14所述的方法，其进一步包括用所述蓬盖保持所述切口打开的步骤。
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