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BRPI0415424A - processo para preparação de composto de aminocrotonila - Google Patents

processo para preparação de composto de aminocrotonila

Info

Publication number
BRPI0415424A
BRPI0415424A BRPI0415424-0A BRPI0415424A BRPI0415424A BR PI0415424 A BRPI0415424 A BR PI0415424A BR PI0415424 A BRPI0415424 A BR PI0415424A BR PI0415424 A BRPI0415424 A BR PI0415424A
Authority
BR
Brazil
Prior art keywords
preparation
aminocrotonyl
amino
compound
buten
Prior art date
Application number
BRPI0415424-0A
Other languages
English (en)
Inventor
Werner Rall
Rainer Soyka
Chistian Kulinna
Juergen Schnaubelt
Peter Sieger
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34428508&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0415424(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Priority to BR122013033343A priority Critical patent/BR122013033343B8/pt
Publication of BRPI0415424A publication Critical patent/BRPI0415424A/pt
Publication of BRPI0415424B1 publication Critical patent/BRPI0415424B1/pt
Publication of BRPI0415424B8 publication Critical patent/BRPI0415424B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

"PROCESSO PARA PREPARAçãO DE COMPOSTOS DE AMINOCROTONILA". A invenção refere-se a um processo aperfeiçoado para preparar 4-¢(3-cloro-4-fluorfenil)aminol-6-{¢4-(N,N-dimetilamino)-1 -oxo-2-buten-1 -il!amino}-7-((S)-tetraldrofuran-3-ilóxi)-quinazolina e compostos de aminocrotonila relacionados e à preparação de um sal adequado de 4-¢(3-cloro-4fluorfenil)amino!-6-{¢4-(N, N-dimetilamino)-1 -oxo-2-buten-1-il!amino}-7-((S)tetraidrofuran-3-il!ilóxi)-quinazolina para uso como uma substância farmaceuticamente ativa.
BRPI0415424A 2003-10-17 2004-10-12 processo para preparação de compostos de aminocrotonila BRPI0415424B8 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122013033343A BR122013033343B8 (pt) 2003-10-17 2004-10-12 dimaleato de 4-[(3-cloro-4-fluorfenil)amino]-6-{[4-(n,n-dimetilamino)-1-oxo-2-buten-1-il]amino}-7-((s)-tetraidrofuran-3-ilóxi)-quinazolina, seu uso e seu processo de preparação, e composições farmacêuticas

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10349113A DE10349113A1 (de) 2003-10-17 2003-10-17 Verfahren zur Herstellung von Aminocrotonylverbindungen
PCT/EP2004/011378 WO2005037824A2 (de) 2003-10-17 2004-10-12 Verfahren zur herstellung von aminocrotonylverbindungen

Publications (3)

Publication Number Publication Date
BRPI0415424A true BRPI0415424A (pt) 2006-12-05
BRPI0415424B1 BRPI0415424B1 (pt) 2019-01-22
BRPI0415424B8 BRPI0415424B8 (pt) 2021-05-25

Family

ID=34428508

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0415424A BRPI0415424B8 (pt) 2003-10-17 2004-10-12 processo para preparação de compostos de aminocrotonila
BR122013033343A BR122013033343B8 (pt) 2003-10-17 2004-10-12 dimaleato de 4-[(3-cloro-4-fluorfenil)amino]-6-{[4-(n,n-dimetilamino)-1-oxo-2-buten-1-il]amino}-7-((s)-tetraidrofuran-3-ilóxi)-quinazolina, seu uso e seu processo de preparação, e composições farmacêuticas

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR122013033343A BR122013033343B8 (pt) 2003-10-17 2004-10-12 dimaleato de 4-[(3-cloro-4-fluorfenil)amino]-6-{[4-(n,n-dimetilamino)-1-oxo-2-buten-1-il]amino}-7-((s)-tetraidrofuran-3-ilóxi)-quinazolina, seu uso e seu processo de preparação, e composições farmacêuticas

Country Status (35)

Country Link
US (2) US20050085495A1 (pt)
EP (2) EP1678165B1 (pt)
JP (2) JP4594317B2 (pt)
KR (2) KR101180752B1 (pt)
CN (2) CN101402631A (pt)
AR (1) AR046118A1 (pt)
AU (2) AU2004281938B2 (pt)
BR (2) BRPI0415424B8 (pt)
CA (2) CA2759063C (pt)
CY (2) CY1114866T1 (pt)
DE (1) DE10349113A1 (pt)
DK (2) DK1678165T3 (pt)
EA (1) EA016624B1 (pt)
EC (1) ECSP066509A (pt)
ES (2) ES2563211T5 (pt)
HK (1) HK1095817A1 (pt)
HR (2) HRP20160246T4 (pt)
HU (1) HUE028254T2 (pt)
IL (2) IL174951A (pt)
ME (1) ME00341B (pt)
MX (2) MXPA06004076A (pt)
MY (2) MY155425A (pt)
NO (2) NO333971B1 (pt)
NZ (2) NZ547154A (pt)
PE (2) PE20100267A1 (pt)
PL (2) PL1678165T3 (pt)
PT (2) PT1678165E (pt)
RS (3) RS60563B1 (pt)
SG (1) SG139743A1 (pt)
SI (2) SI2508521T2 (pt)
TW (2) TWI373470B (pt)
UA (2) UA91006C2 (pt)
UY (2) UY28559A1 (pt)
WO (1) WO2005037824A2 (pt)
ZA (1) ZA200602234B (pt)

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