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ATE312101T1 - Imidazo-pyridin verbindungen, die die sekretion von magensäure hemmen - Google Patents

Imidazo-pyridin verbindungen, die die sekretion von magensäure hemmen

Info

Publication number
ATE312101T1
ATE312101T1 AT99947038T AT99947038T ATE312101T1 AT E312101 T1 ATE312101 T1 AT E312101T1 AT 99947038 T AT99947038 T AT 99947038T AT 99947038 T AT99947038 T AT 99947038T AT E312101 T1 ATE312101 T1 AT E312101T1
Authority
AT
Austria
Prior art keywords
stomachic
imidazo
inhibit
acid secretion
pyridine compounds
Prior art date
Application number
AT99947038T
Other languages
English (en)
Inventor
Kosrat Amin
Michael Dahlstroem
Peter Nordberg
Ingemar Starke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of ATE312101T1 publication Critical patent/ATE312101T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99947038T 1998-04-29 1999-04-23 Imidazo-pyridin verbindungen, die die sekretion von magensäure hemmen ATE312101T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds
PCT/SE1999/000663 WO1999055706A1 (en) 1998-04-29 1999-04-23 Imidazo pyridine derivatives which inhibit gastric acid secretion

Publications (1)

Publication Number Publication Date
ATE312101T1 true ATE312101T1 (de) 2005-12-15

Family

ID=20411154

Family Applications (4)

Application Number Title Priority Date Filing Date
AT99947038T ATE312101T1 (de) 1998-04-29 1999-04-23 Imidazo-pyridin verbindungen, die die sekretion von magensäure hemmen
AT99947037T ATE307130T1 (de) 1998-04-29 1999-04-23 Imidazo-pyridin verbindungen, die die sekretion von magensäure hemmen.
AT04023091T ATE372340T1 (de) 1998-04-29 1999-04-23 Zwischenprodukte für die herstellung von imidazo- pyridin-derivate
AT04023090T ATE372339T1 (de) 1998-04-29 1999-04-23 Zwischenprodukte für die herstellung von imidazo- pyridin-derivate

Family Applications After (3)

Application Number Title Priority Date Filing Date
AT99947037T ATE307130T1 (de) 1998-04-29 1999-04-23 Imidazo-pyridin verbindungen, die die sekretion von magensäure hemmen.
AT04023091T ATE372340T1 (de) 1998-04-29 1999-04-23 Zwischenprodukte für die herstellung von imidazo- pyridin-derivate
AT04023090T ATE372339T1 (de) 1998-04-29 1999-04-23 Zwischenprodukte für die herstellung von imidazo- pyridin-derivate

Country Status (34)

Country Link
US (2) US6313136B1 (de)
EP (4) EP1073656B1 (de)
JP (2) JP3883383B2 (de)
KR (3) KR100650472B1 (de)
CN (2) CN1174980C (de)
AR (2) AR015769A1 (de)
AT (4) ATE312101T1 (de)
AU (2) AU769108B2 (de)
BR (2) BR9909995B1 (de)
CA (2) CA2329922C (de)
CZ (2) CZ293977B6 (de)
DE (4) DE69928792T2 (de)
DK (2) DK1073657T3 (de)
EE (2) EE04676B1 (de)
ES (2) ES2252975T3 (de)
HK (5) HK1033457A1 (de)
HU (2) HUP0102313A3 (de)
ID (2) ID27530A (de)
IL (4) IL139297A0 (de)
IS (2) IS5684A (de)
MY (2) MY121389A (de)
NO (2) NO317262B1 (de)
NZ (2) NZ507638A (de)
PL (2) PL343797A1 (de)
RU (2) RU2235725C2 (de)
SA (2) SA99200064B1 (de)
SE (1) SE9801526D0 (de)
SI (1) SI1073656T1 (de)
SK (2) SK14912000A3 (de)
TR (4) TR200003149T2 (de)
TW (2) TWI250159B (de)
UA (2) UA67769C2 (de)
WO (2) WO1999055706A1 (de)
ZA (2) ZA200005796B (de)

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US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) 2000-09-07 2000-09-07 Astrazeneca Ab New process
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
JP2004518709A (ja) * 2001-02-13 2004-06-24 アストラゼネカ・アクチエボラーグ 新規放出修飾製剤
EE05234B1 (et) * 2001-03-08 2009-12-15 Astrazeneca Ab 6-karboksamidoimidaso[1,2-a] pridiinihendite kasutamine ravimi p?hjustatud maohaavandi v„ltimiseks
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
CA2499639C (en) 2002-09-19 2011-11-08 Schering Corporation Imidazopyridines as cyclin dependent kinase inhibitors
US7326718B2 (en) 2002-11-19 2008-02-05 Altana Pharma Ag 8-Substituted imidazopyridines
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
JP4695588B2 (ja) * 2003-02-26 2011-06-08 スージェン, インク. プロテインキナーゼ阻害剤としてのアミノヘテロアリール化合物
US7470791B2 (en) 2003-03-10 2008-12-30 Nycomed Gmbh Process for the preparation of roflumilast
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CN1874772A (zh) * 2003-11-03 2006-12-06 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2-a]吡啶衍生物
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
EP1711498A2 (de) * 2004-01-26 2006-10-18 Altana Pharma AG 1,2,4-triazolo[1,5-a]pyridine als inhibitoren der sekretion von magensäure
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
WO2006064339A1 (en) * 2004-12-17 2006-06-22 Pfizer Japan Inc. Chromane derivatives useful as acid pump antagonists
CA2601250C (en) 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
KR101300831B1 (ko) * 2005-03-21 2013-08-30 에스*바이오 피티이 리미티드 이미다조[1,2-a]피리딘 유도체, 이의 제조 방법 및 그의약학적 용도
US20080255358A1 (en) * 2005-03-24 2008-10-16 Mark James Bamford Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
CN101326175B (zh) 2005-12-05 2012-07-18 辉瑞产品公司 C-met/hgfr抑制剂的多晶型物
BRPI0619424B1 (pt) 2005-12-05 2022-02-08 Pfizer Products Inc Uso de inibidores c-met/hgfrs para a fabricação de medicamentos
RU2008137145A (ru) * 2006-03-17 2010-03-27 Раквалиа Фарма Инк. (Jp) Производные хромана
WO2008013785A2 (en) 2006-07-24 2008-01-31 Singh-Broemer And Company, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
EP1974729A1 (de) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituierte Imidazopyridinderivate als Melanocortin-4-Rezeptorantagonisten
US8513226B2 (en) * 2008-03-31 2013-08-20 Council Of Scientific And Industrial Research Simultaneous method for the preparation of a mixture of 3-acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3-acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
RU2586276C2 (ru) 2009-07-09 2016-06-10 Раквалиа Фарма Инк. Антагонист кислотного насоса для лечения заболеваний, связанных с патологическим нарушением моторики желудочно-кишечного тракта
CN105358151B (zh) * 2013-06-25 2019-04-12 豪夫迈·罗氏有限公司 用于治疗脊髓性肌萎缩的化合物
US9944637B2 (en) 2013-12-16 2018-04-17 Asana Biosciences, Llc P2X3 and/or P2X2/3 compounds and methods
JP6578298B2 (ja) * 2014-03-24 2019-09-18 アークル インコーポレイテッド 3−(3−(4−(1−アミノシクロブチル)フェニル)−5−フェニル−3h−イミダゾ[4,5−b]ピリジン−2−イル)ピリジン−2−アミンを調製する方法
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
CN111683976B (zh) 2018-02-05 2022-11-18 生物辐射实验室股份有限公司 具有阴离子交换-疏水混合模式配体的色谱树脂
BR112020019277B1 (pt) 2018-04-10 2024-01-16 Bayer Aktiengesellschaft Processo para produção de ácidos 2,6-dialquilfenil acéticos, e seus intermediários
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
WO2021089580A1 (en) 2019-11-04 2021-05-14 Cinclus Pharma Ag Oral formulation of x842
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EP4426694A1 (de) 2021-11-05 2024-09-11 Cinclus Pharma Holding AB (publ) Polymorphe des hydrochloridsalzes von linaprazanglurat
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법
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ZA81219B (en) * 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
DE3269604D1 (en) 1981-06-26 1986-04-10 Schering Corp Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
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GB8722488D0 (en) * 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound

Also Published As

Publication number Publication date
EP1073656B1 (de) 2005-10-19
BR9909996B1 (pt) 2010-08-24
ATE372339T1 (de) 2007-09-15
AU769190B2 (en) 2004-01-22
EP1491542A2 (de) 2004-12-29
SK14922000A3 (sk) 2001-06-11
DE69927803T2 (de) 2006-07-06
HUP0102425A2 (hu) 2001-11-28
CZ293977B6 (cs) 2004-09-15
KR100595805B1 (ko) 2006-07-03
IS5683A (is) 2000-10-25
CZ20003981A3 (cs) 2001-03-14
EP1491543B1 (de) 2007-09-05
DK1073656T3 (da) 2006-01-16
EP1073656A1 (de) 2001-02-07
HK1071139A1 (en) 2005-07-08
EP1491543A1 (de) 2004-12-29
SI1073656T1 (sl) 2006-02-28
AR015768A1 (es) 2001-05-16
UA67769C2 (uk) 2004-07-15
JP3692034B2 (ja) 2005-09-07
IL139297A (en) 2007-06-03
SA99200065B1 (ar) 2006-11-07
ES2249913T3 (es) 2006-04-01
MY121379A (en) 2006-01-28
PL195000B1 (pl) 2007-07-31
DE69937077D1 (de) 2007-10-18
SK14912000A3 (sk) 2001-06-11
JP2002513025A (ja) 2002-05-08
KR100595806B1 (ko) 2006-07-03
DE69927803D1 (de) 2006-03-02
ID26819A (id) 2001-02-15
CZ20003982A3 (cs) 2001-02-14
WO1999055706A9 (en) 2000-03-16
US6313137B1 (en) 2001-11-06
NO317262B1 (no) 2004-09-27
HUP0102425A3 (en) 2002-12-28
AU4300799A (en) 1999-11-16
HK1033317A1 (en) 2001-08-24
WO1999055705A1 (en) 1999-11-04
DE69928792T2 (de) 2006-07-20
TW490466B (en) 2002-06-11
EE200000626A (et) 2002-04-15
IS5684A (is) 2000-10-25
DE69937076T2 (de) 2008-05-29
SE9801526D0 (sv) 1998-04-29
SK285768B6 (sk) 2007-07-06
AU769108B2 (en) 2004-01-15
HUP0102313A2 (hu) 2001-12-28
EP1491542A3 (de) 2005-01-05
DE69928792D1 (de) 2006-01-12
NO20005450L (no) 2000-12-22
NO318203B1 (no) 2005-02-14
CA2329922C (en) 2006-04-11
CN1307577A (zh) 2001-08-08
EE04676B1 (et) 2006-08-15
AR015769A1 (es) 2001-05-16
TWI250159B (en) 2006-03-01
BR9909995B1 (pt) 2010-07-13
NO20005450D0 (no) 2000-10-27
KR20050121760A (ko) 2005-12-27
RU2238271C2 (ru) 2004-10-20
RU2235725C2 (ru) 2004-09-10
ZA200005796B (en) 2002-01-18
EP1073657B1 (de) 2005-12-07
EE200000664A (et) 2002-04-15
IL139200A (en) 2010-04-29
KR20010043133A (ko) 2001-05-25
EP1491542B1 (de) 2007-09-05
MY121389A (en) 2006-01-28
SA99200064B1 (ar) 2006-10-11
CA2329922A1 (en) 1999-11-04
PL343801A1 (en) 2001-09-10
JP3883383B2 (ja) 2007-02-21
NZ507639A (en) 2004-01-30
WO1999055706A1 (en) 1999-11-04
TR200102728T2 (tr) 2002-06-21
TR200003149T2 (tr) 2001-03-21
NO20005451L (no) 2000-12-27
HK1033457A1 (en) 2001-08-31
DE69937076D1 (de) 2007-10-18
DK1073657T3 (da) 2006-03-13
US6313136B1 (en) 2001-11-06
ID27530A (id) 2001-04-12
EE04916B1 (et) 2007-10-15
SA99200065A (ar) 2005-12-03
CN1306533A (zh) 2001-08-01
DE69937077T2 (de) 2008-05-29
KR100650472B1 (ko) 2006-11-28
UA66846C2 (uk) 2004-06-15
ES2252975T3 (es) 2006-05-16
CN1174980C (zh) 2004-11-10
TR200102612T2 (tr) 2002-06-21
IL139297A0 (en) 2001-11-25
IL139200A0 (en) 2001-11-25
JP2002513024A (ja) 2002-05-08
AU4300699A (en) 1999-11-16
EP1073657A1 (de) 2001-02-07
HUP0102313A3 (en) 2002-10-28
KR20010043134A (ko) 2001-05-25
BR9909996A (pt) 2000-12-26
ATE372340T1 (de) 2007-09-15
NZ507638A (en) 2003-10-31
ATE307130T1 (de) 2005-11-15
CN1165535C (zh) 2004-09-08
ZA200005797B (en) 2002-01-18
NO20005451D0 (no) 2000-10-27
BR9909995A (pt) 2000-12-26
HK1036984A1 (en) 2002-01-25
HK1036981A1 (en) 2002-01-25
CA2329921A1 (en) 1999-11-04
CZ292567B6 (cs) 2003-10-15
PL343797A1 (en) 2001-09-10
TR200003176T2 (tr) 2001-03-21

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