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ATE278419T1 - Wässerige immunologische adjuvantzusammensetzungen aus monophosphoryllipid a - Google Patents

Wässerige immunologische adjuvantzusammensetzungen aus monophosphoryllipid a

Info

Publication number
ATE278419T1
ATE278419T1 AT98915239T AT98915239T ATE278419T1 AT E278419 T1 ATE278419 T1 AT E278419T1 AT 98915239 T AT98915239 T AT 98915239T AT 98915239 T AT98915239 T AT 98915239T AT E278419 T1 ATE278419 T1 AT E278419T1
Authority
AT
Austria
Prior art keywords
surfactant
lipid
derivative
attenuated
monophosphoryl lipid
Prior art date
Application number
AT98915239T
Other languages
English (en)
Inventor
R Thomas Crane
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corixa Corp filed Critical Corixa Corp
Application granted granted Critical
Publication of ATE278419T1 publication Critical patent/ATE278419T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT98915239T 1997-04-01 1998-04-01 Wässerige immunologische adjuvantzusammensetzungen aus monophosphoryllipid a ATE278419T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83107397A 1997-04-01 1997-04-01
PCT/US1998/006528 WO1998043670A2 (en) 1997-04-01 1998-04-01 Aqueous immunologic adjuvant compositions of monophosphoryl lipid a

Publications (1)

Publication Number Publication Date
ATE278419T1 true ATE278419T1 (de) 2004-10-15

Family

ID=25258229

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98915239T ATE278419T1 (de) 1997-04-01 1998-04-01 Wässerige immunologische adjuvantzusammensetzungen aus monophosphoryllipid a

Country Status (19)

Country Link
EP (1) EP0971739B1 (de)
JP (1) JP5019494B2 (de)
KR (1) KR100603884B1 (de)
CN (2) CN1259052A (de)
AT (1) ATE278419T1 (de)
AU (1) AU743114B2 (de)
BR (1) BR9811262A (de)
CA (1) CA2284586C (de)
DE (1) DE69826842T2 (de)
ES (1) ES2227825T3 (de)
HK (1) HK1026613A1 (de)
HU (1) HUP0001403A3 (de)
IL (2) IL132126A0 (de)
NO (1) NO994760L (de)
NZ (1) NZ338101A (de)
PL (1) PL190237B1 (de)
PT (1) PT971739E (de)
TR (1) TR199902437T2 (de)
WO (1) WO1998043670A2 (de)

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Also Published As

Publication number Publication date
DE69826842T2 (de) 2005-11-24
CN1575815A (zh) 2005-02-09
KR20010005882A (ko) 2001-01-15
EP0971739B1 (de) 2004-10-06
CA2284586A1 (en) 1998-10-08
ES2227825T3 (es) 2005-04-01
CN1326564C (zh) 2007-07-18
PL336698A1 (en) 2000-07-03
HK1026613A1 (en) 2000-12-22
AU743114B2 (en) 2002-01-17
NO994760L (no) 1999-11-26
HUP0001403A2 (hu) 2000-09-28
CA2284586C (en) 2011-02-08
TR199902437T2 (xx) 2000-01-21
JP2001526640A (ja) 2001-12-18
WO1998043670A3 (en) 1998-12-30
DE69826842D1 (de) 2004-11-11
JP5019494B2 (ja) 2012-09-05
IL132126A0 (en) 2001-03-19
IL132126A (en) 2006-10-05
NZ338101A (en) 2002-03-28
WO1998043670A2 (en) 1998-10-08
CN1259052A (zh) 2000-07-05
HUP0001403A3 (en) 2003-05-28
PT971739E (pt) 2004-12-31
BR9811262A (pt) 2000-10-17
PL190237B1 (pl) 2005-11-30
EP0971739A2 (de) 2000-01-19
KR100603884B1 (ko) 2006-07-24
AU6947398A (en) 1998-10-22
NO994760D0 (no) 1999-09-30

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