[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

PL1828378T3 - Deacylacja lps w bakteriach gram ujemnych - Google Patents

Deacylacja lps w bakteriach gram ujemnych

Info

Publication number
PL1828378T3
PL1828378T3 PL05815467T PL05815467T PL1828378T3 PL 1828378 T3 PL1828378 T3 PL 1828378T3 PL 05815467 T PL05815467 T PL 05815467T PL 05815467 T PL05815467 T PL 05815467T PL 1828378 T3 PL1828378 T3 PL 1828378T3
Authority
PL
Poland
Prior art keywords
deacylation
lps
negative bacteria
gram negative
gram
Prior art date
Application number
PL05815467T
Other languages
English (en)
Inventor
Johannes Petrus Maria Tommassen
Der Ley Peter André Van
Jeroen Johannes Gerardus Geurtsen
Original Assignee
De Staat Der Nederlanden Vert Door De Mini Van Vws Mini Van Volksgezondheid Welzijn En Sport
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by De Staat Der Nederlanden Vert Door De Mini Van Vws Mini Van Volksgezondheid Welzijn En Sport filed Critical De Staat Der Nederlanden Vert Door De Mini Van Vws Mini Van Volksgezondheid Welzijn En Sport
Publication of PL1828378T3 publication Critical patent/PL1828378T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL05815467T 2004-12-17 2005-12-16 Deacylacja lps w bakteriach gram ujemnych PL1828378T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04078445 2004-12-17
PCT/NL2005/050081 WO2006065139A2 (en) 2004-12-17 2005-12-16 Deacylation of lps in gram negative bacteria
EP05815467.5A EP1828378B1 (en) 2004-12-17 2005-12-16 Deacylation of lps in gram negative bacteria

Publications (1)

Publication Number Publication Date
PL1828378T3 true PL1828378T3 (pl) 2014-10-31

Family

ID=34928754

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05815467T PL1828378T3 (pl) 2004-12-17 2005-12-16 Deacylacja lps w bakteriach gram ujemnych

Country Status (15)

Country Link
US (1) US8048433B2 (pl)
EP (1) EP1828378B1 (pl)
JP (1) JP5378685B2 (pl)
CN (1) CN101203605B (pl)
AU (1) AU2005317304B2 (pl)
BR (1) BRPI0519923A8 (pl)
CA (1) CA2590906C (pl)
DK (1) DK1828378T3 (pl)
ES (1) ES2493440T3 (pl)
MX (1) MX2007007288A (pl)
NO (1) NO340331B1 (pl)
NZ (1) NZ555889A (pl)
PL (1) PL1828378T3 (pl)
PT (1) PT1828378E (pl)
WO (1) WO2006065139A2 (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2393682T3 (es) * 2007-03-26 2012-12-27 De Staat Der Nederlanden, Vert. Door De Minister Van Vws Vacunas mejoradas contra Bordotella pertussis basadas en mutantes de glicosiltransferasa LPS
AU2013301312A1 (en) 2012-08-06 2015-03-19 Glaxosmithkline Biologicals S.A. Method for eliciting in infants an immune response against RSV and B. pertussis
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
EA031879B1 (ru) 2013-06-04 2019-03-29 Пётр Геннадиевич Апарин Модифицированный липополисахарид эндотоксичных бактерий (варианты), комбинация модифицированных липополисахаридов (варианты) и включающие их вакцина (варианты) и фармацевтическая композиция (варианты)
US11052142B2 (en) 2013-06-04 2021-07-06 Petr G. Aparin Modified endotoxic bacteria lipopolysaccharide (variants), combination of modified lipopolysaccharides (variants) and, containing same, a vaccine (variants) and a pharmaceutical composition (variants)
CN105555304A (zh) 2013-08-05 2016-05-04 葛兰素史密丝克莱恩生物有限公司 联合免疫原性组合物
WO2015179270A2 (en) 2014-05-19 2015-11-26 Board Of Regents, The University Of Texas System Combinatorial platform for the display of surface adjuvants and antigens
CN104388368B (zh) * 2014-10-30 2017-02-15 四川农业大学 一株低内毒素大肠杆菌原核表达工程菌突变株及构建方法
US11389520B2 (en) * 2016-01-28 2022-07-19 Intravacc B.V. Modified tetra-acylated neisserial LPS
CN105567620B (zh) * 2016-01-29 2019-03-19 江南大学 一株产减毒类脂A的Cronobacter sakazakii突变株及其应用
CN105695540A (zh) * 2016-03-18 2016-06-22 辽宁成大生物股份有限公司 一种革兰氏阴性菌胞壁抗原的制备方法
AU2018233139B2 (en) * 2017-03-13 2022-06-16 Intravacc B.V. Bordetella vaccines comprising LPS with reduced reactogenicity
CA3063419A1 (en) * 2017-05-15 2018-11-22 University Of Maryland, Baltimore Live salmonella typhi vectors engineered to express heterologous outer membrane protein antigens and methods of use thereof
CA3084274A1 (en) * 2017-12-04 2019-06-13 De Staat Der Nederlanden, Vert. Door De Minister Van Vws, Ministerie Van Volksgezondheid, Welzijn En Sport An improved process for producing outer membrane vesicles
WO2022049222A1 (en) 2020-09-04 2022-03-10 Intravacc B.V. Ompa mutations enhance omv production in bordetella pertussis
EP4169513A1 (en) 2021-10-19 2023-04-26 GlaxoSmithKline Biologicals S.A. Adjuvant composition comprising sting agonists

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH650681A5 (en) * 1981-08-14 1985-08-15 Dso Pharmachim Whooping cough vaccine
KR0168039B1 (ko) * 1987-09-04 1999-01-15 로버트 디. 웨스트 재조합 dna에서 유도한 보르데텔라 외독소 소단위체의 유사체 및 그를 포함하는 백신
EP0484621A3 (en) * 1990-07-11 1992-08-26 American Cyanamid Company Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens
JPH08500734A (ja) * 1992-08-18 1996-01-30 デュファル インターナショナル リサーチ ベスローテン フェンノートシャップ 気管支敗血症菌（Ｂｏｒｄｅｔｅｌｌａ ｂｒｏｎｃｈｉｓｅｐｔｉｃａ）ワクチン
DE69625191T2 (de) * 1995-05-04 2003-07-10 Aventis Pasteur Ltd., Toronto Azelluläre pertussis impfstoffe und verfahren zur herstellung
US6887483B2 (en) * 1995-12-01 2005-05-03 University Of Iowa Research Foundation Non-toxic mutants of pathogenic gram-negative bacteria
TR199902437T2 (xx) * 1997-04-01 2000-01-21 Corixa Corporation Monofosforil lipid A'ya ait sulu im�nolojik adjuvant terkipleri.
CA2264970A1 (en) * 1998-03-10 1999-09-10 American Cyanamid Company Antigenic conjugates of conserved lipolysaccharides of gram negative bacteria
DE69838460T3 (de) * 1998-11-03 2014-04-30 De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur LPS mit reduzierter Toxizität von genetisch modifizierten Gram-Negativen Bakterien
US6531131B1 (en) * 1999-08-10 2003-03-11 The United States Of America As Represented By The Department Of Health And Human Services Conjugate vaccine for Neisseria meningitidis
US20030113742A1 (en) * 2001-04-20 2003-06-19 University Of Iowa Research Foundation Methods and compositions for the modulation of biofilm formation

Also Published As

Publication number Publication date
ES2493440T3 (es) 2014-09-11
NO340331B1 (no) 2017-04-03
DK1828378T3 (da) 2014-09-01
CA2590906A1 (en) 2006-06-22
JP5378685B2 (ja) 2013-12-25
WO2006065139A2 (en) 2006-06-22
AU2005317304B2 (en) 2011-06-23
MX2007007288A (es) 2008-02-25
CN101203605A (zh) 2008-06-18
JP2008523805A (ja) 2008-07-10
US20080274145A1 (en) 2008-11-06
BRPI0519923A8 (pt) 2018-01-23
CA2590906C (en) 2017-01-03
AU2005317304A1 (en) 2006-06-22
NO20073088L (no) 2007-09-17
PT1828378E (pt) 2014-10-10
EP1828378A2 (en) 2007-09-05
NZ555889A (en) 2009-07-31
EP1828378B1 (en) 2014-06-11
CN101203605B (zh) 2016-01-27
WO2006065139A3 (en) 2006-10-19
US8048433B2 (en) 2011-11-01
BRPI0519923A2 (pt) 2009-08-11

Similar Documents

Publication Publication Date Title
GB0422052D0 (en) Enzymes
ZA200803859B (en) Novel 2-amino-heterocycles useful in the treatment of abeta-related pathologies
GB0307026D0 (en) Bacterial supplement
PT1828378E (pt) Deacilação de lps em bactérias de gram negativo
IL172988A0 (en) Bioreactor
GB0604973D0 (en) Purification method and kit
GB0410118D0 (en) Novel bioreactor
EP1848798A4 (en) NEW MICROBIAL ENZYMES AND THEIR USE
HK1105357A1 (zh) 腸營養物
GB0511602D0 (en) Microorganisms
EP1937307A4 (en) SPECIFIC ELIMINATION OF ACTIVATED IMMUNE CELLS
IL180459A0 (en) Treatment of bacterial infections
GB0410958D0 (en) Methods for reducing biofilm formation in infectious bacteria
EP1969128A4 (en) INDUCTION OF A PHYSIOLOGICAL DISPERSION RESPONSE TO BACTERIAL CELLS IN A BIOFILM
GB0426182D0 (en) Photoporation of cells
GB2408702B (en) Bioreactor
HUP0401841A2 (en) Combined micropropagating process and bioreactor
GB0403452D0 (en) Desaturase enzymes
GB0522696D0 (en) Balustrading kit and method
GB0419204D0 (en) Bacteria
GB0319436D0 (en) Improvements in enzymes
AU2004900839A0 (en) Bacterial treatment
AU2004907245A0 (en) Bacterial treatment
GB0315183D0 (en) Bioreactor
GB0312042D0 (en) Bioreactor