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MA55364A - Bioconjugués d'antigènes polysaccharidiques o d'e. coli, procédés de production de ces derniers, et méthodes d'utilisation de ces derniers - Google Patents

Bioconjugués d'antigènes polysaccharidiques o d'e. coli, procédés de production de ces derniers, et méthodes d'utilisation de ces derniers

Info

Publication number
MA55364A
MA55364A MA055364A MA55364A MA55364A MA 55364 A MA55364 A MA 55364A MA 055364 A MA055364 A MA 055364A MA 55364 A MA55364 A MA 55364A MA 55364 A MA55364 A MA 55364A
Authority
MA
Morocco
Prior art keywords
methods
bioconjugates
coli
producing
polysaccharidic
Prior art date
Application number
MA055364A
Other languages
English (en)
Inventor
Darren Robert Abbanat
Martin Edward Braun
Pieter Jan Burghout
Sandmeier Maria Paula Carranza
Kellen Cristhina Fae
Fonck Veronica Gambillara
Jeroen Geurtsen
Yon Patricia Ibarra
Stefan Jochen Kemmler
Michael Thomas Kowarik
Manuela Mally
Jan Theunis Poolman
Eveline Marleen Weerdenburg
Original Assignee
Glaxosmithkline Biologicals Sa
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals Sa, Janssen Pharmaceuticals Inc filed Critical Glaxosmithkline Biologicals Sa
Publication of MA55364A publication Critical patent/MA55364A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0258Escherichia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/01Hexosyltransferases (2.4.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
MA055364A 2019-03-18 2020-03-18 Bioconjugués d'antigènes polysaccharidiques o d'e. coli, procédés de production de ces derniers, et méthodes d'utilisation de ces derniers MA55364A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962819746P 2019-03-18 2019-03-18

Publications (1)

Publication Number Publication Date
MA55364A true MA55364A (fr) 2022-01-26

Family

ID=70285927

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055364A MA55364A (fr) 2019-03-18 2020-03-18 Bioconjugués d'antigènes polysaccharidiques o d'e. coli, procédés de production de ces derniers, et méthodes d'utilisation de ces derniers

Country Status (23)

Country Link
US (3) US11446370B2 (fr)
EP (1) EP3941516A1 (fr)
JP (1) JP7370391B2 (fr)
KR (1) KR102532707B1 (fr)
CN (1) CN113924112A (fr)
AR (1) AR118388A1 (fr)
AU (1) AU2020240072A1 (fr)
BR (1) BR112021018236A2 (fr)
CA (1) CA3134216A1 (fr)
CL (1) CL2021002426A1 (fr)
CO (1) CO2021013823A2 (fr)
CR (1) CR20210522A (fr)
EA (1) EA202192390A1 (fr)
IL (1) IL286394A (fr)
JO (1) JOP20210256A1 (fr)
MA (1) MA55364A (fr)
MX (1) MX2021011445A (fr)
PE (1) PE20212265A1 (fr)
SA (1) SA521430310B1 (fr)
SG (1) SG11202110301TA (fr)
TW (1) TWI751513B (fr)
UY (1) UY38616A (fr)
WO (1) WO2020191082A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
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HUE038915T2 (hu) 2013-01-17 2018-12-28 Arsanis Biosciences Gmbh MDR E. colira fajlagos antitest
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TWI715617B (zh) 2015-08-24 2021-01-11 比利時商葛蘭素史密斯克藍生物品公司 對抗腸道外病原性大腸桿菌之免疫保護之方法及組合物
AR109621A1 (es) 2016-10-24 2018-12-26 Janssen Pharmaceuticals Inc Formulaciones de vacunas contra glucoconjugados de expec
MA55364A (fr) 2019-03-18 2022-01-26 Glaxosmithkline Biologicals Sa Bioconjugués d'antigènes polysaccharidiques o d'e. coli, procédés de production de ces derniers, et méthodes d'utilisation de ces derniers
TWI771663B (zh) 2019-03-18 2022-07-21 美商詹森藥物公司 E. coli O-抗原多醣生物結合物之製備方法、其組合物及其使用方法
BR112023004819A2 (pt) * 2020-09-17 2023-04-18 Janssen Pharmaceuticals Inc Composições de vacinas multivalentes e seus usos
JP7495578B2 (ja) 2020-11-30 2024-06-04 ヤンセン ファーマシューティカルズ,インコーポレーテッド キャピラリーベースのイムノアッセイシステムを使用する複合糖質の分析方法
AU2022251305A1 (en) 2021-04-01 2023-09-07 Janssen Pharmaceuticals, Inc. Production of e. coli o18 bioconjugates
WO2022214620A1 (fr) 2021-04-08 2022-10-13 Janssen Pharmaceuticals, Inc. Procédé de production de bioconjugués
CN116003531B (zh) * 2022-12-28 2023-09-05 山东省农业科学院畜牧兽医研究所 噬菌体受体结合蛋白po86在大肠杆菌o抗原血清型分型鉴定中的应用

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MA55364A (fr) 2019-03-18 2022-01-26 Glaxosmithkline Biologicals Sa Bioconjugués d'antigènes polysaccharidiques o d'e. coli, procédés de production de ces derniers, et méthodes d'utilisation de ces derniers
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Also Published As

Publication number Publication date
KR20210141586A (ko) 2021-11-23
KR102532707B1 (ko) 2023-05-12
SA521430310B1 (ar) 2023-12-13
AR118388A1 (es) 2021-09-29
TW202102255A (zh) 2021-01-16
MX2021011445A (es) 2021-10-13
EP3941516A1 (fr) 2022-01-26
JOP20210256A1 (ar) 2023-01-30
US20200316184A1 (en) 2020-10-08
CO2021013823A2 (es) 2022-03-29
CL2021002426A1 (es) 2022-04-29
CR20210522A (es) 2021-12-17
US11931405B2 (en) 2024-03-19
WO2020191082A9 (fr) 2020-11-05
JP7370391B2 (ja) 2023-10-27
IL286394A (en) 2021-10-31
BR112021018236A2 (pt) 2021-11-23
AU2020240072A1 (en) 2021-10-28
US20240316172A1 (en) 2024-09-26
EA202192390A1 (ru) 2021-12-03
PE20212265A1 (es) 2021-11-30
US20230118878A1 (en) 2023-04-20
TWI751513B (zh) 2022-01-01
UY38616A (es) 2020-09-30
JP2022533883A (ja) 2022-07-27
SG11202110301TA (en) 2021-10-28
WO2020191082A1 (fr) 2020-09-24
CA3134216A1 (fr) 2020-09-24
CN113924112A (zh) 2022-01-11
US11446370B2 (en) 2022-09-20

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