NZ503551A - PDE4 inhibitors for the treatment of inflammatory skin diseases - Google Patents

PDE4 inhibitors for the treatment of inflammatory skin diseases

Info

Publication number: NZ503551A
Authority: NZ; New Zealand
Prior art keywords: xanthine; use according; compound; cyclopropylmethyl; butyl
Prior art date: 1997-10-17

Application number

NZ503551A

Other languages

English (en)

Inventor

Don E Griswold

Siegfried Benjamin Christensen

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-17

Filing date

1998-10-16

Publication date

2002-05-31

1998-10-16 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2002-05-31 Publication of NZ503551A publication Critical patent/NZ503551A/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NZ503551A 1997-10-17 1998-10-16 PDE4 inhibitors for the treatment of inflammatory skin diseases NZ503551A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US6374697P	1997-10-17	1997-10-17
PCT/US1998/021886 WO1999020280A1 (en)	1997-10-17	1998-10-16	Novel use of compounds for anti-pruritic activity

Publications (1)

Publication Number	Publication Date
NZ503551A true NZ503551A (en)	2002-05-31

Family

ID=22051225

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NZ503551A NZ503551A (en)	1997-10-17	1998-10-16	PDE4 inhibitors for the treatment of inflammatory skin diseases

Country Status (18)

Country	Link
EP (1)	EP1030666A4 (cs)
JP (1)	JP2001520196A (cs)
KR (1)	KR20010031149A (cs)
CN (1)	CN1306426A (cs)
AR (1)	AR015966A1 (cs)
AU (1)	AU740875B2 (cs)
BR (1)	BR9814080A (cs)
CA (1)	CA2306985A1 (cs)
CO (1)	CO4810374A1 (cs)
CZ (1)	CZ20001376A3 (cs)
HU (1)	HUP0003792A3 (cs)
IL (1)	IL135581A0 (cs)
NO (1)	NO20001847D0 (cs)
NZ (1)	NZ503551A (cs)
PL (1)	PL341062A1 (cs)
TR (1)	TR200001040T2 (cs)
WO (1)	WO1999020280A1 (cs)
ZA (1)	ZA989450B (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR0116850A (pt)	2001-01-31	2004-02-25	Pfizer Prod Inc	Derivados de amida de ácido tiazolil-, oxazolil-, pirrolil- e imidazolil- úteis como inibidores de isoenzimas de pde4
ATE305467T1 (de)	2001-01-31	2005-10-15	Pfizer Prod Inc	Als inhibitoren von pde4-isozymen geeignete etherderivate
SK8792003A3 (en)	2001-01-31	2004-09-08	Pfizer Prod Inc	Nicotinamide biaryl derivatives useful as inhibitors of PDE4 isozymes and pharmaceutical composition containing them
US7250518B2 (en)	2001-01-31	2007-07-31	Pfizer Inc.	Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
US20030175314A1 (en) *	2001-11-19	2003-09-18	Didriksen Erik Johannes	Pharmaceutical composition for dermal application
US20060258703A1 (en) *	2003-07-17	2006-11-16	Ono Pharmaceutical Co., Ltd.	Remedy for pruritus comprising piperidine derivative as the active ingredient
JP2005187458A (ja) *	2003-12-04	2005-07-14	Santen Pharmaceut Co Ltd	シロミラストまたはその塩を有効成分とする掻痒治療剤
WO2005053672A1 (ja) *	2003-12-04	2005-06-16	Santen Pharmaceutical Co., Ltd.	シロミラストまたはその塩を有効成分とする掻痒治療剤
AU2005212816C1 (en) *	2004-02-14	2010-03-04	Glaxosmithkline Llc	Novel compounds
JP2008137892A (ja) *	2005-03-04	2008-06-19	Eisai Co Ltd	止痒剤
TW200800217A (en)	2005-08-10	2008-01-01	Smithkline Beecham Corp	Novel compounds
TWI404709B (zh) *	2006-02-21	2013-08-11	Eisai R&D Man Co Ltd	4- (3-benzamidophenyl) -6,7-dimethoxy-2-methylamine quinazoline derivatives
WO2007097317A1 (ja) *	2006-02-21	2007-08-30	Eisai R & D Management Co., Ltd.	４－（３－ベンゾイルアミノフェニル）－６，７－ジメトキシ－２－メチルアミノキナゾリン誘導体
AU2008215411B2 (en)	2007-02-16	2012-11-22	Eisai R & D Management Co., Ltd.	Crystal, amorphous form and salt of methyl N-[3-(6,7-dimethoxy- 2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid
CN101687820B (zh)	2007-08-17	2012-07-25	卫材R&D管理有限公司	喹唑啉衍生物的制造方法
WO2009025239A1 (ja)	2007-08-17	2009-02-26	Eisai R & D Management Co., Ltd.	新規外用剤
ES2659458T3 (es) *	2011-06-28	2018-03-15	Mitsubishi Tanabe Pharma Corporation	Compuestos de naftaleno para tratar el prurito
AU2016212625B2 (en)	2015-01-30	2020-03-26	Shanton Pharma Pte. Ltd.	Prevention or treatment of uric acid or gout disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1992011260A1 (en) *	1990-12-21	1992-07-09	Beecham Group Plc	Xanthine derivatives
EP0889886B1 (de) *	1996-03-26	2002-09-18	ALTANA Pharma AG	Neue in 6-position substituierte phenanthridine
ES2187775T3 (es) *	1996-05-15	2003-06-16	Altana Pharma Ag	Imidazopiridinas.
WO1998040382A1 (en) *	1997-03-07	1998-09-17	Byk Gulden Lomberg Chemische Fabrik Gmbh	Novel tetrazoles
SK122199A3 (en) *	1997-03-18	2000-12-11	Basf Ag	Methods and compositions for modulating responsiveness to corticosteroids
SI0988302T1 (en) *	1997-06-03	2003-08-31	Altana Pharma Ag	Benzonaphthyridines

1998
- 1998-10-15 AR ARP980105131A patent/AR015966A1/es not_active Application Discontinuation
- 1998-10-16 TR TR2000/01040T patent/TR200001040T2/xx unknown
- 1998-10-16 CO CO98060225A patent/CO4810374A1/es unknown
- 1998-10-16 IL IL13558198A patent/IL135581A0/xx unknown
- 1998-10-16 EP EP98953608A patent/EP1030666A4/en not_active Withdrawn
- 1998-10-16 PL PL98341062A patent/PL341062A1/xx unknown
- 1998-10-16 KR KR1020007004053A patent/KR20010031149A/ko not_active Application Discontinuation
- 1998-10-16 JP JP2000516677A patent/JP2001520196A/ja not_active Withdrawn
- 1998-10-16 WO PCT/US1998/021886 patent/WO1999020280A1/en not_active Application Discontinuation
- 1998-10-16 CA CA002306985A patent/CA2306985A1/en not_active Abandoned
- 1998-10-16 CZ CZ20001376A patent/CZ20001376A3/cs unknown
- 1998-10-16 NZ NZ503551A patent/NZ503551A/en unknown
- 1998-10-16 HU HU0003792A patent/HUP0003792A3/hu unknown
- 1998-10-16 AU AU10938/99A patent/AU740875B2/en not_active Ceased
- 1998-10-16 BR BR9814080-9A patent/BR9814080A/pt not_active IP Right Cessation
- 1998-10-16 CN CN98810066A patent/CN1306426A/zh active Pending
- 1998-10-16 ZA ZA989450A patent/ZA989450B/xx unknown
2000
- 2000-04-10 NO NO20001847A patent/NO20001847D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP0003792A3 (en)	2001-12-28
CZ20001376A3 (cs)	2002-06-12
NO20001847L (no)	2000-04-10
AU1093899A (en)	1999-05-10
HUP0003792A2 (hu)	2001-10-28
TR200001040T2 (tr)	2001-01-22
CN1306426A (zh)	2001-08-01
AR015966A1 (es)	2001-05-30
IL135581A0 (en)	2001-05-20
EP1030666A1 (en)	2000-08-30
ZA989450B (en)	1999-04-19
PL341062A1 (en)	2001-03-26
CO4810374A1 (es)	1999-06-30
AU740875B2 (en)	2001-11-15
KR20010031149A (ko)	2001-04-16
EP1030666A4 (en)	2002-10-16
CA2306985A1 (en)	1999-04-29
BR9814080A (pt)	2000-09-26
JP2001520196A (ja)	2001-10-30
NO20001847D0 (no)	2000-04-10
WO1999020280A1 (en)	1999-04-29

Publication	Publication Date	Title
AU740875B2 (en)	2001-11-15	Novel use of compounds for anti-pruritic activity
Golightly et al.	1988	Pharmaceutical excipients: adverse effects associated with inactive ingredients in drug products (Part I)
EP2059259A1 (en)	2009-05-20	Pharmaceutical compositions for the treatment of fungal infections
WO2008091704A2 (en)	2008-07-31	Treatment of cushing's syndrome and autism
US6897229B2 (en)	2005-05-24	Synergistic combination comprising roflumilast and a PDE-3 inhibitor
CA2136977A1 (en)	1993-12-09	_-8-tetrahydro-cannabinol as antiemetic
JPS62185014A (ja)	1987-08-13	複合調剤薬
JPH02160720A (ja)	1990-06-20	医薬組成物
JPWO2006041121A1 (ja)	2008-05-15	慢性皮膚疾患の治療および／または予防剤
AU3578289A (en)	1989-11-24	Certain paf antagonist antihistamine combinations and methods
JP3276762B2 (ja)	2002-04-22	イソキノリン誘導体を含有する医薬組成物
MXPA00003775A (en)	2001-03-05	Novel use of compounds for anti-pruritic activity
CA2368650C (en)	2005-09-13	Viral treatment
ES2378374T3 (es)	2012-04-11	Inhibidores de la PDE 4 para el tratamiento de la cistitis intersticial
JPH03215435A (ja)	1991-09-20	アルドース還元酵素阻害剤を主成分とする潰瘍治療剤
AU592851B2 (en)	1990-01-25	Transdermal formulations
US5981538A (en)	1999-11-09	Methods of treating psoriasis employing substituted azaspiranes
JPS6245525A (ja)	1987-02-27	脂質低下剤
GB1588095A (en)	1981-04-15	Composition for the treatment of scabies
US20060079513A1 (en)	2006-04-13	Methods and compositions including methscopolamine nitrate
AU1563902A (en)	2002-03-28	Novel use of compounds for anti-pruritic activity
JP2004026810A (ja)	2004-01-29	鼻炎用組成物
EP2037934A2 (en)	2009-03-25	An anti-viral composition for the topical treatment of herpes labialis (cold sores) and method for use thereof
JPH02501574A (ja)	1990-05-31	増殖過剰性皮膚疾患処置用組成物
US20060079514A1 (en)	2006-04-13	Methods and compositions including methscopolamine bromide

Legal Events

Date	Code	Title	Description
2002-09-27	PSEA	Patent sealed
2002-10-25	RENW	Renewal (renewal fees accepted)