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NL151066B - Werkwijze voor de bereiding van preparaten met antidepressieve eigenschappen, alsmede werkwijze voor de bereiding van daarvoor geschikte diaminen. - Google Patents

Werkwijze voor de bereiding van preparaten met antidepressieve eigenschappen, alsmede werkwijze voor de bereiding van daarvoor geschikte diaminen.

Info

Publication number
NL151066B
NL151066B NL666613406A NL6613406A NL151066B NL 151066 B NL151066 B NL 151066B NL 666613406 A NL666613406 A NL 666613406A NL 6613406 A NL6613406 A NL 6613406A NL 151066 B NL151066 B NL 151066B
Authority
NL
Netherlands
Prior art keywords
preparation
preparations
procedure
suitable diamines
antidepressive properties
Prior art date
Application number
NL666613406A
Other languages
English (en)
Other versions
NL6613406A (nl
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL6613406A publication Critical patent/NL6613406A/xx
Publication of NL151066B publication Critical patent/NL151066B/nl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL666613406A 1965-09-22 1966-09-22 Werkwijze voor de bereiding van preparaten met antidepressieve eigenschappen, alsmede werkwijze voor de bereiding van daarvoor geschikte diaminen. NL151066B (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48938165A 1965-09-22 1965-09-22
US75868368A 1968-09-10 1968-09-10

Publications (2)

Publication Number Publication Date
NL6613406A NL6613406A (nl) 1967-03-23
NL151066B true NL151066B (nl) 1976-10-15

Family

ID=27049698

Family Applications (3)

Application Number Title Priority Date Filing Date
NL6613323A NL6613323A (nl) 1965-09-22 1966-09-21
NL666613406A NL151066B (nl) 1965-09-22 1966-09-22 Werkwijze voor de bereiding van preparaten met antidepressieve eigenschappen, alsmede werkwijze voor de bereiding van daarvoor geschikte diaminen.
NL6613405A NL6613405A (nl) 1965-09-22 1966-09-22

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NL6613323A NL6613323A (nl) 1965-09-22 1966-09-21

Family Applications After (1)

Application Number Title Priority Date Filing Date
NL6613405A NL6613405A (nl) 1965-09-22 1966-09-22

Country Status (12)

Country Link
US (2) US3431304A (nl)
BE (3) BE686909A (nl)
BR (3) BR6683056D0 (nl)
CH (2) CH525862A (nl)
DE (2) DE1543666A1 (nl)
DK (1) DK129924B (nl)
FI (1) FI46154C (nl)
FR (5) FR6162M (nl)
IL (1) IL26508A (nl)
NL (3) NL6613323A (nl)
NO (1) NO119593B (nl)
SE (1) SE344064B (nl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904690A (en) * 1965-12-03 1975-09-09 Oreal 2-Nitro-meta-phenylenediamines
US4155934A (en) * 1965-12-03 1979-05-22 L'oreal Hair dye compounds
GB1274307A (en) * 1968-06-13 1972-05-17 Sumitomo Chemical Co Process for producing aminobenzophenone derivatives and their salts
US3927010A (en) * 1969-10-17 1975-12-16 Hoffmann La Roche Diarylmethane derivatives and processes for their preparation
US3904603A (en) * 1974-08-01 1975-09-09 American Home Prod 2,3,4,5-tetrahydro-4,4-dialkyl-1h-1,4-benzodiazepine halides
JPS6019753A (ja) * 1983-07-13 1985-01-31 Shionogi & Co Ltd オルト−(モノ置換アミノ)フエニルイミン類およびその製造法
US4560510A (en) * 1984-04-06 1985-12-24 A. H. Robins Company, Incorporated Process and intermediates for the preparation of aryl substituted pyrido[1,4]benzodiazepines

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3222359A (en) * 1965-12-07 Process for preparing benzodiazepine compounds
US3131178A (en) * 1964-04-28 Process for producing s-phenyl-l
US3182054A (en) * 1965-05-04 Benzodiazepine - compounds
US3141890A (en) * 1964-07-21 Certificate of correction
US3136815A (en) * 1959-12-10 1964-06-09 Hoffmann La Roche Amino substituted benzophenone oximes and derivatives thereof
US3239564A (en) * 1960-12-02 1966-03-08 Reeder Earl 2 n-substituted amino halobenzo-phenones
US3203990A (en) * 1962-03-21 1965-08-31 Hoffmann La Roche 2-amino-2'-halo-5-nitro benzophenones

Also Published As

Publication number Publication date
BR6683054D0 (pt) 1973-12-04
BE687122A (nl) 1967-03-20
NL6613405A (nl) 1967-03-23
SE344064B (nl) 1972-03-27
FR6670M (nl) 1969-02-03
FR6162M (nl) 1968-07-08
BR6683056D0 (pt) 1973-12-04
US3431304A (en) 1969-03-04
FR1508140A (fr) 1968-01-05
BR6683057D0 (pt) 1973-12-04
DK129924C (nl) 1975-05-12
NL6613406A (nl) 1967-03-23
US3562325A (en) 1971-02-09
NO119593B (nl) 1970-06-08
NL6613323A (nl) 1967-03-23
IL26508A (en) 1971-04-28
CH537902A (de) 1973-07-31
DE1543668A1 (de) 1972-04-13
CH525862A (de) 1972-07-31
DK129924B (da) 1974-12-02
FR1500341A (fr) 1967-11-03
BE687123A (nl) 1967-03-20
FI46154B (nl) 1972-10-02
DE1543666A1 (de) 1969-09-11
FI46154C (fi) 1973-01-10
BE686909A (nl) 1967-03-15
FR1493255A (fr) 1967-08-25

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Legal Events

Date Code Title Description
V1 Lapsed because of non-payment of the annual fee
NL80 Abbreviated name of patent owner mentioned of already nullified patent

Owner name: HOFFMANN