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ZA989450B - Novel use of compounds for anti-pruritic activity - Google Patents

Novel use of compounds for anti-pruritic activity

Info

Publication number
ZA989450B
ZA989450B ZA989450A ZA989450A ZA989450B ZA 989450 B ZA989450 B ZA 989450B ZA 989450 A ZA989450 A ZA 989450A ZA 989450 A ZA989450 A ZA 989450A ZA 989450 B ZA989450 B ZA 989450B
Authority
ZA
South Africa
Prior art keywords
compounds
novel use
pruritic activity
pruritic
activity
Prior art date
Application number
ZA989450A
Other languages
English (en)
Inventor
Don E Griswold
Siegfried B Christensen Iv
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA989450B publication Critical patent/ZA989450B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA989450A 1997-10-17 1998-10-16 Novel use of compounds for anti-pruritic activity ZA989450B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6374697P 1997-10-17 1997-10-17

Publications (1)

Publication Number Publication Date
ZA989450B true ZA989450B (en) 1999-04-19

Family

ID=22051225

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA989450A ZA989450B (en) 1997-10-17 1998-10-16 Novel use of compounds for anti-pruritic activity

Country Status (18)

Country Link
EP (1) EP1030666A4 (no)
JP (1) JP2001520196A (no)
KR (1) KR20010031149A (no)
CN (1) CN1306426A (no)
AR (1) AR015966A1 (no)
AU (1) AU740875B2 (no)
BR (1) BR9814080A (no)
CA (1) CA2306985A1 (no)
CO (1) CO4810374A1 (no)
CZ (1) CZ20001376A3 (no)
HU (1) HUP0003792A3 (no)
IL (1) IL135581A0 (no)
NO (1) NO20001847L (no)
NZ (1) NZ503551A (no)
PL (1) PL341062A1 (no)
TR (1) TR200001040T2 (no)
WO (1) WO1999020280A1 (no)
ZA (1) ZA989450B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7250518B2 (en) 2001-01-31 2007-07-31 Pfizer Inc. Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
BR0116850A (pt) 2001-01-31 2004-02-25 Pfizer Prod Inc Derivados de amida de ácido tiazolil-, oxazolil-, pirrolil- e imidazolil- úteis como inibidores de isoenzimas de pde4
BR0116852A (pt) 2001-01-31 2004-02-25 Pfizer Prod Inc Derivados biarilados de nicotinamida úteis como inibidores de isozimas pde4
ES2248231T3 (es) 2001-01-31 2006-03-16 Pfizer Products Inc. Derivados de eteres utiles como inhibidores de las isozimas pde4.
US20030175314A1 (en) * 2001-11-19 2003-09-18 Didriksen Erik Johannes Pharmaceutical composition for dermal application
WO2005007161A1 (ja) * 2003-07-17 2005-01-27 Santen Pharmaceutical Co., Ltd. ピペリジン誘導体を有効成分とする掻痒治療剤
WO2005053672A1 (ja) * 2003-12-04 2005-06-16 Santen Pharmaceutical Co., Ltd. シロミラストまたはその塩を有効成分とする掻痒治療剤
JP2005187458A (ja) * 2003-12-04 2005-07-14 Santen Pharmaceut Co Ltd シロミラストまたはその塩を有効成分とする掻痒治療剤
DK1781657T3 (da) 2004-02-14 2013-06-10 Glaxosmithkline Ip Dev Ltd Medikamenter med hm74a-receptor aktivitet
JP2008137892A (ja) * 2005-03-04 2008-06-19 Eisai Co Ltd 止痒剤
EA014556B1 (ru) 2005-08-10 2010-12-30 ГЛЭКСОСМИТКЛАЙН ЭлЭлСи Производные ксантина в качестве селективных агонистов hm74a
TWI404709B (zh) * 2006-02-21 2013-08-11 Eisai R&D Man Co Ltd 4- (3-benzamidophenyl) -6,7-dimethoxy-2-methylamine quinazoline derivatives
WO2007097317A1 (ja) * 2006-02-21 2007-08-30 Eisai R & D Management Co., Ltd. ４－（３－ベンゾイルアミノフェニル）－６，７－ジメトキシ－２－メチルアミノキナゾリン誘導体
WO2008099887A1 (ja) 2007-02-16 2008-08-21 Eisai R & D Management Co., Ltd. メチル ｎ－［３－（６，７－ジメトキシ－２－メチルアミノキナゾリン－４－イル）フェニル］テレフタラミックアシッドの結晶、非晶質体または塩
WO2009025238A1 (ja) 2007-08-17 2009-02-26 Eisai R & D Management Co., Ltd. キナゾリン誘導体の製造方法
CN101687819B (zh) 2007-08-17 2013-03-20 卫材R&D管理有限公司 外用剂
WO2013002196A1 (ja) * 2011-06-28 2013-01-03 田辺三菱製薬株式会社 新規医薬組成物
SG10201907026RA (en) 2015-01-30 2019-09-27 Shanton Pharma Co Ltd Prevention or Treatment of Uratic or Gouty Diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0563168B1 (en) * 1990-12-21 2000-07-05 Beecham Group Plc Xanthine derivatives
PT889886E (pt) * 1996-03-26 2003-02-28 Altana Pharma Ag Novas fenantridinas substituidas na posicao 6
EP0912568B1 (en) * 1996-05-15 2002-11-20 ALTANA Pharma AG imidazopyridines
ATE248167T1 (de) * 1997-03-07 2003-09-15 Altana Pharma Ag Tetrazole derivate
WO1998041232A2 (en) * 1997-03-18 1998-09-24 Basf Aktiengesellschaft Compositions for modulating responsiveness to corticosteroids
DE69811492T2 (de) * 1997-06-03 2004-02-05 Altana Pharma Ag Benzonaphthyridine

Also Published As

Publication number Publication date
HUP0003792A3 (en) 2001-12-28
AR015966A1 (es) 2001-05-30
CO4810374A1 (es) 1999-06-30
AU1093899A (en) 1999-05-10
WO1999020280A1 (en) 1999-04-29
JP2001520196A (ja) 2001-10-30
BR9814080A (pt) 2000-09-26
IL135581A0 (en) 2001-05-20
CZ20001376A3 (cs) 2002-06-12
KR20010031149A (ko) 2001-04-16
PL341062A1 (en) 2001-03-26
CA2306985A1 (en) 1999-04-29
CN1306426A (zh) 2001-08-01
HUP0003792A2 (hu) 2001-10-28
EP1030666A4 (en) 2002-10-16
NZ503551A (en) 2002-05-31
NO20001847D0 (no) 2000-04-10
EP1030666A1 (en) 2000-08-30
NO20001847L (no) 2000-04-10
TR200001040T2 (tr) 2001-01-22
AU740875B2 (en) 2001-11-15

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