[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

WO2015149391A1 - Préparation de médecine chinoise traditionnelle pour le traitement de l'entérite chronique et son procédé de préparation - Google Patents

Préparation de médecine chinoise traditionnelle pour le traitement de l'entérite chronique et son procédé de préparation Download PDF

Info

Publication number
WO2015149391A1
WO2015149391A1 PCT/CN2014/075338 CN2014075338W WO2015149391A1 WO 2015149391 A1 WO2015149391 A1 WO 2015149391A1 CN 2014075338 W CN2014075338 W CN 2014075338W WO 2015149391 A1 WO2015149391 A1 WO 2015149391A1
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
chinese medicine
traditional chinese
add
licorice
Prior art date
Application number
PCT/CN2014/075338
Other languages
English (en)
Chinese (zh)
Inventor
袁志贤
Original Assignee
袁志贤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 袁志贤 filed Critical 袁志贤
Publication of WO2015149391A1 publication Critical patent/WO2015149391A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285—Aucklandia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/344—Codonopsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A61K36/835—Aquilaria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Definitions

  • the invention relates to a traditional Chinese medicine preparation for treating enteritis, in particular to a traditional Chinese medicine preparation for treating chronic enteritis and a preparation method thereof.
  • the intestine refers to the digestive tract from the pylorus of the stomach to the anus.
  • the intestine is the longest part of the digestive tract and is the most important part of the function.
  • the intestine is the largest digestive organ of the human body and the largest detoxification organ in the human body. From the perspective of physiology, anatomy, and cytology, large intestine detoxification accounts for more than 85 % of human detoxification; 80% of the human body's immune structure is around the intestine, and endotoxin accumulation is the killer of autoimmune immunity.
  • Enteritis mainly refers to gastroenteritis, enteritis, and colitis, and is generally thought to be caused by bacteria, viruses, fungi, and parasites.
  • the main clinical manifestations are nausea, vomiting, abdominal pain, diarrhea, bloody stools, and stools. Some patients may have fever and a feeling of urgency.
  • the incidence of chronic enteritis is on the rise, and the course of the disease is long, difficult to cure, repeated attacks, seriously affecting people's health and quality of life, and The cancer rate is about 5%.
  • the drugs currently used to treat enteritis are not small, Western medicines are not cured, and they are prone to drug resistance for a long time.
  • the side effects are relatively large, which damages the liver, kidneys and blood cells, and the drug is unstable and easy to recur. Summary of the invention
  • the object of the present invention is to provide a traditional Chinese medicine preparation for treating chronic enteritis on the basis of the above-mentioned deficiencies, combined with modern Chinese and Western medicine technology, and in particular to provide such a traditional Chinese medicine preparation and a preparation method thereof, the enteritis of the present invention
  • the treatment effect is obvious, and it is non-toxic, has no side effects, and has stable effects, and the preparation process is simple and easy.
  • the preparation of the invention is from cassia twig, codonopsis pilosula, dried ginger, ginseng ginseng, licorice, woody scent, oyster shell, longan nucleus, bergamot, chicken inner gold, orange peel, agarwood, angelica, maiden, calcined scorpion, yellow sage, large
  • the preparation of the composition prepared by blood vine, white peony and jujube, wherein the mass ratio of each component is: cassia twig 12-20g: ginseng 10-22g dried ginger 8-18g ginseng ginseng 10-18g licorice 8-15g woody
  • Astragalus 10-18g blood vine 8-16g white peony 8-15g jujube 10-20g (
  • the preferred raw material quality ratio of the present invention is: Guizhi 12-18g Codonopsis 10-18g Dried ginger 8-12g Prince 12-18g Licorice 8-12g Woody
  • the present invention is also preferable as a raw material cassia 15g Codonopsis 12g dried ginger 9g prince 15g licorice 10g woody 12g
  • the above preparation method for treating a traditional Chinese medicine preparation for chronic enteritis comprises the following steps:
  • Codonopsis in a small pot and stir fry until the surface is slightly coke, and then crushed by a pulverizer and passed through a 80 mesh sieve for use; Astragalus membranaceus and big blood vine are proportioned well, pulverized into powder by a pulverizer and passed through a 90 mesh sieve, and dried naturally for use;
  • step 3 mix the powders of each component in step 1) and 2), add boiling water twice, add 10 times pure water for 1 hour, extract the filtrate for use; 6 times pure water decoction for half an hour, then combine the decoction and filter, spare;
  • step 5 mixing the powders of each component in step 4), adding 4 to 6 times 70% ⁇ 80% ethanol, heating and refluxing for 3 to 5 hours, extracting and filtering to obtain a filtrate; and then remaining the dregs Adding 2 to 4 times of 65% to 75% ethanol again, heating and refluxing for 2 to 3 hours, extracting and filtering to obtain a filtrate; combining the filtrates obtained twice, removing the ethanol solvent under reduced pressure, and drying to obtain a dry paste. ;
  • the dry paste obtained in the above step 5) is ultra-pulverized into a powder and passed through a 200 mesh sieve, and then the powder is added to 3) the combined decoction in the step, and the mixture is shaken to obtain.
  • the prepared Chinese medicine composition solution preparation can be used for oral administration, and if it can be consumed once in the morning and evening, and it is used for a long time, the effect is better.
  • the theoretical basis of the invention is: cassia twig, which is a dry twig of cinnamon of the evergreen tree plant of the family Aphididae, mainly produced in Guangxi, Guangdong and Yunnan. Cut the shoots in spring and summer, dry or dry, cut into thin slices or small sections.
  • the taste of Xin Wen has the function of warming the veins, dispelling the cold, and treating the qi stagnation caused by insufficient yang Blood coagulation, abdominal pain, cold blood stasis, etc., can also treat colds caused by cold, cold, cough and other diseases have a good effect.
  • the extract of osmanthus fragrans can inhibit Escherichia coli, Bacillus subtilis and Staphylococcus aureus in vitro, with an effective concentration of 25 mg/ml or less; against Staphylococcus aureus, Shigella dysenteriae, Typhoid fever and Parahaemolyticus, Pneumococcal , Azotobacter, Proteus, Bacillus anthracis, Salmonella enteritidis, Vibrio cholerae, etc. also have inhibitory effects. Codonopsis pilosula has anti-gastrointestinal mucosal damage, pharmacological effects related to Buzhong Yiqi and spleen-suppressing effects to adjust gastrointestinal motility and anti-ulcer.
  • Dangshen has the functions of enhancing immune function, enhancing hematopoietic function, anti-stress, cardiotonic, anti-shock, regulating blood pressure, resisting myocardial ischemia and inhibiting platelet aggregation.
  • Dangshen also has the functions of puzzle, calmness, hypnosis and anti-convulsion. Dangshen has the effect of replenishing vital energy, strengthening the spleen and benefiting the lungs. For spleen and lung weakness.
  • Dried ginger is a dried ginger, spicy, hot, spleen, stomach, heart, lung. It has the effect of warming and dispelling cold, returning to Yangtongmai, warming lung and drinking. It is used for spleen and stomach yang deficiency and has a cold syndrome.
  • Radix Pseudostellariae also known as ginseng
  • ginseng is a kind of ginseng. It has a calming, sweet taste and a tonifying effect. It is often used for spleen and stomach weakness, lack of stomach yin, fatigue, indigestion, loss of appetite and so on.
  • Licorice a kind of tonic Chinese herbal medicine, the medicinal parts are roots and rhizomes. The roots of the medicinal properties are cylindrical, with spleen and qi, clearing away heat and detoxification, relieving cough, relieving pain, and reconciling various medicines.
  • Woody is the general name for the genus Yunmuxiang and Chuanmuxiang, and is the dry root of the woody scent of Compositae. Woody has an antibacterial effect, can inhibit the regeneration of gastrointestinal bacteria, and can also inhibit the reproduction of liver virus replication, and play a role in reducing inflammation and protecting the liver.
  • Clam shell bitter taste, cool, into the lungs, spleen, large intestine, broken gas, sputum, elimination, treatment of chest stagnation, chest, bloating, food, belching, vomiting, diarrhea Heavy, rectal prolapse, uterine prolapse and other effects.
  • Longan core, miso, qi and pain, hemostasis, moisture absorption, etc. can be used for hernia pain, traumatic bleeding, phlegm, wet sores and so on. Disperse wind and evil spirits, cure dizziness, deafness, and vertigo.
  • bergamot also known as the five-finger orange, bergamot, its roots, stems, leaves, flowers, and fruit can be used as medicine, bitter, spicy, sweet, warm, into the liver, spleen, stomach, lung, rational gasification, coughing It has many medicinal functions such as swelling, soothing liver and strengthening spleen and gastrointestinal tract.
  • Chenpi alias agarwood, spicy, bitter, warm; spleen, stomach, lung; qi scent, can be ascending or descending; Chenpi's bitter substance is represented by limonin and bitterin ", this kind of lemon bitter tastes calm, easy to dissolve in water, helps digestion of food; has the effect of qi and medium, dampness and phlegm, and water and laxative. Indications for spleen and stomach discomfort, abdominal pain, spleen and stomach weakness, loss of appetite, vomiting hiccups, limb weakness and other symptoms, and Codonopsis, dried ginger, yam equivalent, the effect is better.
  • Angelica a perennial herb, distributed in Gansu, Yunnan, Sichuan, Qinghai, Shaanxi, Hunan, Hubei, Guizhou, etc., cultivated everywhere.
  • the root of Angelica is one of the most commonly used Chinese medicines.
  • Angelica has the effect of warming meridians, promoting blood circulation and relieving pain, whether it is cold and abdominal pain, or rheumatoid joint pain, or bruises and blood stasis. Angelica is also commonly used in hemorrhoids. Because Angelica activating blood circulation and dissipating blood stasis, it can reduce swelling and relieve pain and discharge pus muscle.
  • the famous Fangfang Xiagging Live Drink for treating sores is equivalent to Angelica and Red Oak, Honeysuckle and Gunsan.
  • Ophiopogon japonicus is a perennial evergreen grass plant of the genus Liliaceae. The fibrous roots are thicker and thicker.
  • the top or middle part of the root is often expanded into a spindle-shaped succulent piece, which is used as a root. Slightly cold, taste It is slightly bitter and medicinal experiments have proved that Maimendong has the effect of increasing white blood cells, prolonging the existence time of antibodies, improving immune function and nucleic acid synthesis rate, and promoting the production of immune substances such as antibodies, complement, interferon and lysozyme. Therefore, Ophiopogon has the effect of strengthening the righteousness and strengthening the anti-evil effect, thereby reducing the incidence of disease. It is used for lung and stomach yin deficiency, less thirst, dry cough and hemoptysis, heart yin deficiency, heart irritability and fever, and late heat injury.
  • Calcined scorpion sweet, flat, liver, lung, stomach. It has the effects of eliminating phlegm and dissipating phlegm, softening and firming, and acid-relieving pain. Mainly used for pantothenic acid, stubborn accumulation, sticky and difficult to embolize. Astragalus, Astragalus, alias Camellia root, earth tea root. For the plant of the Labiatae, the root is used as a medicine. It has heat and dampness, cool blood and fetus, detoxification effect.
  • the clinical application of Astragalus is better than berberine and does not produce drug resistance. Big blood vine, bitter, flat.
  • Jujube, sweet and warm, spleen and stomach rich in protein, fat, sugar, carotene, B vitamins, vitamin C, vitamin P and calcium, phosphorus, iron and cyclic adenosine monophosphate and other nutrients.
  • the content of vitamin C is among the best in the fruit, and it has the reputation of vitamin king. It has the effect of replenishing vital energy, strengthening the spleen and stomach, nourishing blood and calming the nerves, and alleviating the medicinal properties. It is used for spleen deficiency, fatigue, and impotence.
  • the pathogenesis is characterized by imaginary inclusion, so the above traditional Chinese medicine by the present invention
  • the composition obtained by the compatibility and the preparation method can effectively achieve the effect of regulating the intestinal tract and the internal organs by using a dialectical method, has no toxic and side effects, and has stable effects, and achieves twice the result with half the effort with western medicine.
  • the oral solution of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for a course of treatment, and 3 courses of treatment as therapeutic effects.
  • the oral solution of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for a course of treatment, and 3 courses for observation of curative effect.
  • the oral solution of the preparation of the present invention is taken half an hour after a meal, 3 times a day, 200 ml each time, 2 months for a course of treatment, and 3 courses for observation of curative effect.
  • the preparation prepared by the invention has good effects for treating chronic enteritis, is non-toxic, has no side effects, has stable effects, and is simple and easy to prepare. Concrete real
  • the preparation of the invention is from cassia twig, codonopsis pilosula, dried ginger, ginseng ginseng, licorice, woody scent, oyster shell, longan nucleus, bergamot, chicken inner gold, orange peel, agarwood, angelica, yoghurt, calcined scorpion, scutellaria, big blood
  • a preparation preparation of vine, white peony and jujube, wherein the mass ratio of each component is Guizhi 12g Codonopsis 10g
  • the above preparation method for treating a traditional Chinese medicine preparation for chronic enteritis comprises the following steps:
  • Codonopsis in a small pot and stir fry until the surface is slightly coke, and then crushed by a pulverizer and passed through a 80 mesh sieve for use; Astragalus membranaceus and big blood vine are proportioned well, pulverized into powder by a pulverizer and passed through a 90 mesh sieve, and dried naturally for use;
  • step 5 mixing the powders of each component in step 4), adding 4 to 6 times 70% ⁇ 80% ethanol, heating and refluxing for 3 to 5 hours, extracting and filtering to obtain a filtrate; and then remaining the dregs Adding 2 to 4 times of 65% to 75% ethanol again, heating and refluxing for 2 to 3 hours, extracting and filtering to obtain a filtrate; combining the filtrates obtained twice, removing the ethanol solvent under reduced pressure, and drying to obtain a dry paste. ;
  • the dry paste obtained in the above step 5) is ultra-pulverized into a powder and passed through a 200 mesh sieve, and then the powder is added to the combined decoction in the step 3), and mixed and shaken to obtain.
  • the preparation of the above-mentioned traditional Chinese medicine composition solution can be used for oral administration, and if it can be consumed once in the morning and evening and long-term drinking, the effect is better.
  • the preferred raw material quality of the present invention is (g):
  • the preparation method is as in Example 1.
  • the preferred raw material quality of the present invention is (g):
  • the preparation method is as in Example 1.
  • the preferred raw material quality of the present invention is (g):
  • the preparation method is as in Example 1.
  • the preferred raw material quality of the present invention is (g):
  • Codonopsis 18g Dried ginger 15g Radix Pseudostellariae 14g Licorice 15g Woody 18g Clam shell 15g Longan nucleus 18g Bergamot 14g Chicken inner gold 18g Tangerine 16g Agarwood 14g Angelica 12g Ophiopogon 13g Calcined scorpion Astragalus 18g Large blood vine 15g White peony 15g 18g
  • the preparation method is as in Example 1.
  • the preferred raw material quality of the present invention is (g):
  • the preparation method is as in Example 1.

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La présente invention concerne une préparation de médecine chinoise traditionnelle pour le traitement de l'entérite chronique et son procédé de préparation, comprenant Ramulus cinnamomi, Codonopsis pilosula, du gingembre séché, Pseudostellaria heterophylla, de la réglisse, des racines de Vladimiria commune, Fructus aurantii, des graines de longane, Citrus medica sarcodactylis, Gallus gallus domesticus Brisson, Pericarpium Citri reticulatae, Aquilaria agallocha, Angelica sinensis, Ophiopogon japonicus, Arca inflata Reeve calciné, Scutellaria baicalensis, Sargentodoxa cuneata, Bletilla striata et de la jujube, lesdits ingrédients étant soumis à des processus de pulvérisation, de décoction, d'extraction par l'éthanol et de mélange dans une préparation liquide.
PCT/CN2014/075338 2014-03-31 2014-04-15 Préparation de médecine chinoise traditionnelle pour le traitement de l'entérite chronique et son procédé de préparation WO2015149391A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410123803.6A CN103877548A (zh) 2014-03-31 2014-03-31 一种治疗慢性肠炎的中药制剂及其制备方法
CN201410123803.6 2014-03-31

Publications (1)

Publication Number Publication Date
WO2015149391A1 true WO2015149391A1 (fr) 2015-10-08

Family

ID=50946884

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2014/075338 WO2015149391A1 (fr) 2014-03-31 2014-04-15 Préparation de médecine chinoise traditionnelle pour le traitement de l'entérite chronique et son procédé de préparation

Country Status (2)

Country Link
CN (1) CN103877548A (fr)
WO (1) WO2015149391A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109364228A (zh) * 2018-12-03 2019-02-22 湖南新汇制药股份有限公司 一种黄芪桂枝五物汤、制备方法及其应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104435929A (zh) * 2014-11-08 2015-03-25 王亚东 一种治疗慢性胃溃疡的中药配方

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181617A (zh) * 2007-12-04 2008-05-21 朱惠芬 一种治疗胃肠疾病的中药制剂
CN101244203A (zh) * 2008-02-03 2008-08-20 李爱英 一种治疗急慢性胃、肠炎的中药
CN103301439A (zh) * 2013-07-09 2013-09-18 朱克兰 一种治疗慢性肠炎的中药组合物及其制备方法
CN103893726A (zh) * 2014-03-31 2014-07-02 袁志贤 治疗慢性胃炎的中药制剂及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100421725C (zh) * 2006-08-22 2008-10-01 夏金陵 一种治疗胃炎的中药组合物及其制备方法
CN101468171B (zh) * 2007-12-28 2011-08-24 何顺洪 一种肥者减肥、瘦者长肉的药物
CN102430008B (zh) * 2008-12-24 2013-10-23 天津中新药业集团股份有限公司乐仁堂制药厂 治疗胃肠疾病中药组合物及其制备方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101181617A (zh) * 2007-12-04 2008-05-21 朱惠芬 一种治疗胃肠疾病的中药制剂
CN101244203A (zh) * 2008-02-03 2008-08-20 李爱英 一种治疗急慢性胃、肠炎的中药
CN103301439A (zh) * 2013-07-09 2013-09-18 朱克兰 一种治疗慢性肠炎的中药组合物及其制备方法
CN103893726A (zh) * 2014-03-31 2014-07-02 袁志贤 治疗慢性胃炎的中药制剂及其制备方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109364228A (zh) * 2018-12-03 2019-02-22 湖南新汇制药股份有限公司 一种黄芪桂枝五物汤、制备方法及其应用

Also Published As

Publication number Publication date
CN103877548A (zh) 2014-06-25

Similar Documents

Publication Publication Date Title
CN104758953A (zh) 一种胃肠道造影剂
CN104147572A (zh) 感冒发热疏风散热制剂及制备方法
CN103861014B (zh) 一种治疗慢性胃炎的中药口服液
CN104001045A (zh) 一种用于治疗犬肺炎的药物及其制备方法
WO2015149391A1 (fr) Préparation de médecine chinoise traditionnelle pour le traitement de l'entérite chronique et son procédé de préparation
WO2015149393A1 (fr) Médecine chinoise traditionnelle pour le traitement de la gastrite chronique et son procédé de préparation
WO2015149395A1 (fr) Préparation de médecine chinoise traditionnelle pour le traitement de la gastrite chronique et son procédé de préparation
CN103417911A (zh) 化疗辅助用中药组合物
CN104984237A (zh) 一种中药组合物及其制备方法
CN104740405B (zh) 一种治疗过敏性紫癜性肾损害的中药制剂及制备方法
CN103735906A (zh) 一种治疗干性支气管扩张的中药制剂及其制备方法
CN105597011A (zh) 一种制备治疗急慢性鼻炎的中药组合物的方法
CN103585434B (zh) 一种治疗贫血的中药组合物
CN101318007A (zh) 一种食道癌胃癌用中药胶囊
CN104398902A (zh) 虚寒型慢性支气管炎清热宣肺制剂及制法
CN105311565A (zh) 一种防治淋巴癌的中药制剂及制法
CN104721670A (zh) 一种治疗咽喉炎的中药组合物及制备方法
WO2015149392A1 (fr) Préparation d'un médicament traditionnel chinois destiné à traiter une colite chronique et son procédé de préparation
CN104147166B (zh) 败血症初期清凉解毒饮及制法
CN106166263A (zh) 根治疟疾的中药浓缩丸
WO2019015102A1 (fr) Médicament de médecine chinoise traditionnelle pour le traitement de la pancréatite aiguë
CN104491792A (zh) 治疗虚寒型慢性支气管炎药剂及制备方法
WO2015149396A1 (fr) Préparation de médecine chinoise traditionnelle permettant le traitement de la gastrite superficielle, et son procédé de préparation
CN105079440A (zh) 一种防治哮喘的润肺化痰制剂及制法
WO2015149389A1 (fr) Médicament issu de la médecine traditionnelle chinoise destiné au traitement de l'entérite chronique et procédé de préparation associé

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 14888254

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

32PN Ep: public notification in the ep bulletin as address of the adressee cannot be established

Free format text: NOTING OF LOSS OF RIGHTS PURSUANT TO RULE 112(1) EPC

122 Ep: pct application non-entry in european phase

Ref document number: 14888254

Country of ref document: EP

Kind code of ref document: A1