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UA96922C2 - Il-12/p40 binding protein - Google Patents

Il-12/p40 binding protein

Info

Publication number
UA96922C2
UA96922C2 UAA200801144A UAA200801144A UA96922C2 UA 96922 C2 UA96922 C2 UA 96922C2 UA A200801144 A UAA200801144 A UA A200801144A UA A200801144 A UAA200801144 A UA A200801144A UA 96922 C2 UA96922 C2 UA 96922C2
Authority
UA
Ukraine
Prior art keywords
binding protein
binding
protein
relates
hil
Prior art date
Application number
UAA200801144A
Other languages
English (en)
Ukrainian (uk)
Inventor
Сюзан Э. Лейси
Эмма ФАНГ
Джонатан П. БЕЛК
Ричард У. Диксон
Майкл Рогуска
Пол Р. ХИНТОН
Шанкар КУМАР
Original Assignee
Эббот Леборейториз
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эббот Леборейториз filed Critical Эббот Леборейториз
Publication of UA96922C2 publication Critical patent/UA96922C2/ru

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
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    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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Abstract

Изобретение относится к связующему белку, который содержит антигенсвязующий домен, в частности антитела, где указанный связующий белок способен связывать р40 субединицу IL-12 человека, нуклеиновой кислоты, которая его кодирует, вектору, способу продуцирования указанного белка, фармацевтической композиции, а также к применению связующего белка для изготовления лекарственного средства для лечения расстройства или заболевания, при котором активность IL-12 является вредной.
UAA200801144A 2005-06-30 2006-06-29 Il-12/p40 binding protein UA96922C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69567905P 2005-06-30 2005-06-30

Publications (1)

Publication Number Publication Date
UA96922C2 true UA96922C2 (en) 2011-12-26

Family

ID=37605037

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200801144A UA96922C2 (en) 2005-06-30 2006-06-29 Il-12/p40 binding protein

Country Status (18)

Country Link
US (3) US7700739B2 (ru)
EP (1) EP1907421A4 (ru)
JP (2) JP5396080B2 (ru)
KR (2) KR20130080058A (ru)
CN (11) CN103145839A (ru)
AU (1) AU2006265932B2 (ru)
BR (1) BRPI0611714A2 (ru)
CA (2) CA2848662A1 (ru)
CR (10) CR9599A (ru)
IL (3) IL187691A (ru)
MX (1) MX2007016401A (ru)
NO (1) NO20080557L (ru)
NZ (1) NZ596992A (ru)
RU (1) RU2461571C2 (ru)
TW (2) TW200745160A (ru)
UA (1) UA96922C2 (ru)
WO (1) WO2007005608A2 (ru)
ZA (1) ZA201201216B (ru)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103145839A (zh) * 2005-06-30 2013-06-12 Abbvie公司 Il-12/p40结合蛋白
US20080199460A1 (en) 2005-09-01 2008-08-21 Schering Corporation Use of IL-23 and IL-17 antagonists to treat autoimmune ocular inflammatory disease
CA2647348A1 (en) 2006-03-28 2007-10-04 Javelin Pharmaceuticals, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
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