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CR20130155A - PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599) - Google Patents

PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)

Info

Publication number
CR20130155A
CR20130155A CR20130155A CR20130155A CR20130155A CR 20130155 A CR20130155 A CR 20130155A CR 20130155 A CR20130155 A CR 20130155A CR 20130155 A CR20130155 A CR 20130155A CR 20130155 A CR20130155 A CR 20130155A
Authority
CR
Costa Rica
Prior art keywords
proteins
divisional
union
antibodies
hil
Prior art date
Application number
CR20130155A
Other languages
English (en)
Inventor
Susan E Lacy
Emma Fung
Jonathan P Belk
Richard W Dixon
Michael Roguska
Paul R Hinton
Shankar Kumar
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of CR20130155A publication Critical patent/CR20130155A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
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  • Hematology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
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  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
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Abstract

Proteínas de unión a IL-12 p40, en particular anticuerpos que se unen a la interleuquina-12 humana (hIL-12) y/o IL-23 humana (hIL-23). Específicamente, la invención se relaciona con anticuerpos que son quiméricos, con injertos de CDR y anticuerpos humanizados.
CR20130155A 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599) CR20130155A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69567905P 2005-06-30 2005-06-30

Publications (1)

Publication Number Publication Date
CR20130155A true CR20130155A (es) 2013-05-23

Family

ID=37605037

Family Applications (10)

Application Number Title Priority Date Filing Date
CR9599A CR9599A (es) 2005-06-30 2007-12-18 Proteinas de union a il-12/p40
CR20130151A CR20130151A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130156A CR20130156A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional 9599)
CR20130157A CR20130157A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130152A CR20130152A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional 9599)
CR20130155A CR20130155A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130153A CR20130153A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130150A CR20130150A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional exp. 9599)
CR20130154A CR20130154A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional exp. 9599)
CR20130149A CR20130149A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional 9599)

Family Applications Before (5)

Application Number Title Priority Date Filing Date
CR9599A CR9599A (es) 2005-06-30 2007-12-18 Proteinas de union a il-12/p40
CR20130151A CR20130151A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130156A CR20130156A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional 9599)
CR20130157A CR20130157A (es) 2005-06-30 2013-04-03 PROTEÍNAS DE LA UNIÓN A IL-12/P40 (Divisional 9599)
CR20130152A CR20130152A (es) 2005-06-30 2013-04-03 Proteínas de la unión a il-12/p40 (divisional 9599)

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CR20130154A (es) 2013-05-23
CN103172739A (zh) 2013-06-26
US8629257B2 (en) 2014-01-14
US20140178332A1 (en) 2014-06-26
JP5396080B2 (ja) 2014-01-22
CN101379085B (zh) 2013-03-27
TW201444869A (zh) 2014-12-01
EP1907421A4 (en) 2012-03-28
CN103146708A (zh) 2013-06-12
CN103172737A (zh) 2013-06-26
US7700739B2 (en) 2010-04-20
US20100047245A1 (en) 2010-02-25
RU2008103312A (ru) 2009-08-10
TW200745160A (en) 2007-12-16
CN101379085A (zh) 2009-03-04
MX2007016401A (es) 2008-02-20
CR20130149A (es) 2013-05-23
JP2013177405A (ja) 2013-09-09
CN103145842A (zh) 2013-06-12
IL187691A (en) 2013-10-31
NZ596992A (en) 2013-07-26
CR20130152A (es) 2013-05-23
ZA201201216B (en) 2012-11-28
CN103145838A (zh) 2013-06-12
CN103145840A (zh) 2013-06-12

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