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UA111272C2 - Конденсовані піримідинові похідні для інгібування тирозинкіназної активності - Google Patents

Конденсовані піримідинові похідні для інгібування тирозинкіназної активності

Info

Publication number
UA111272C2
UA111272C2 UAA201410791A UAA201410791A UA111272C2 UA 111272 C2 UA111272 C2 UA 111272C2 UA A201410791 A UAA201410791 A UA A201410791A UA A201410791 A UAA201410791 A UA A201410791A UA 111272 C2 UA111272 C2 UA 111272C2
Authority
UA
Ukraine
Prior art keywords
condensed
activity
tyrozincinase
inhibition
pirimidine derivatives
Prior art date
Application number
UAA201410791A
Other languages
English (en)
Inventor
Мі Янг Ча
Сеок Дзонг КАНГ
Мі Ра Кім
Дзу Йєон Лі
Дзі Янг Дзеон
Міоунг Гі Дзо
Єун Дзоо Квак
Кванг Ок Лі
Тає Хеє Ха
Квеє Хіун Сух
Маєнг Суп Кім
Original Assignee
Ханмі Сайєнс Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45371929&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA111272(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ханмі Сайєнс Ко., Лтд. filed Critical Ханмі Сайєнс Ко., Лтд.
Publication of UA111272C2 publication Critical patent/UA111272C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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Abstract

Даний винахід стосується конденсованого піримідинового похідного, що має інгібувальну активність відносно тирозинкіназ, і фармацевтичної композиції для профілактики або лікування раку, пухлин, запальних захворювань, аутоімунних захворювань або імунологічно опосередкованих захворювань, яка містить таке похідне як активний інгредієнт.
UAA201410791A 2010-06-23 2011-06-20 Конденсовані піримідинові похідні для інгібування тирозинкіназної активності UA111272C2 (uk)

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