SK285557B6 - Tetrahydropyridíny, spôsob ich prípravy, farmaceutické kompozície obsahujúce tieto tetrahydropyridíny a ich použitie - Google Patents

Tetrahydropyridíny, spôsob ich prípravy, farmaceutické kompozície obsahujúce tieto tetrahydropyridíny a ich použitie Download PDF

Info

Publication number: SK285557B6
Authority: SK; Slovakia
Prior art keywords: formula; compound; disease; solvates; salts
Prior art date: 2000-01-06

Application number

SK962-2002A

Other languages

English (en)

Slovak (sk)

Other versions

SK9622002A3 (en

Inventor

Marco Baroni

Bernard Bourrie

Rosanna Cardamone

Pierre Casellas

Original Assignee

Sanofi - Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-06

Filing date

2000-12-29

Publication date

2007-03-01

2000-12-29 Application filed by Sanofi - Aventis filed Critical Sanofi - Aventis

2003-03-04 Publication of SK9622002A3 publication Critical patent/SK9622002A3/sk

2007-03-01 Publication of SK285557B6 publication Critical patent/SK285557B6/sk

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Tropical Medicine & Parasitology (AREA)
Physical Education & Sports Medicine (AREA)
Pulmonology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Cardiology (AREA)
Dermatology (AREA)
Endocrinology (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
AIDS & HIV (AREA)
Pain & Pain Management (AREA)
Molecular Biology (AREA)

SK962-2002A 2000-01-06 2000-12-29 Tetrahydropyridíny, spôsob ich prípravy, farmaceutické kompozície obsahujúce tieto tetrahydropyridíny a ich použitie SK285557B6 (sk)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0000113A FR2803593B1 (fr)	2000-01-06	2000-01-06	Nouvelles tetrahydropyridines, procede pour leur preparation et compositions pharmaceutiques les contenant
PCT/FR2000/003741 WO2001049684A1 (fr)	2000-01-06	2000-12-29	Nouvelles tetrahydropyridines, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (2)

Publication Number	Publication Date
SK9622002A3 SK9622002A3 (en)	2003-03-04
SK285557B6 true SK285557B6 (sk)	2007-03-01

Family

ID=8845654

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK962-2002A SK285557B6 (sk)	2000-01-06	2000-12-29	Tetrahydropyridíny, spôsob ich prípravy, farmaceutické kompozície obsahujúce tieto tetrahydropyridíny a ich použitie

Country Status (28)

Country	Link
US (1)	US6689797B2 (de)
EP (1)	EP1248785B1 (de)
JP (1)	JP2004501861A (de)
KR (1)	KR100755103B1 (de)
CN (1)	CN1200939C (de)
AT (1)	ATE297918T1 (de)
AU (1)	AU782650B2 (de)
BR (1)	BR0016921A (de)
CA (1)	CA2395969C (de)
CZ (1)	CZ300658B6 (de)
DE (1)	DE60020885T2 (de)
EA (1)	EA004858B1 (de)
EE (1)	EE04814B1 (de)
FR (1)	FR2803593B1 (de)
HK (1)	HK1050532A1 (de)
HU (1)	HU224815B1 (de)
IL (1)	IL150605A0 (de)
IS (1)	IS2472B (de)
ME (1)	MEP21808A (de)
MX (1)	MXPA02006709A (de)
NO (1)	NO322598B1 (de)
NZ (1)	NZ519723A (de)
PL (1)	PL202761B1 (de)
RS (1)	RS50432B (de)
SK (1)	SK285557B6 (de)
UA (1)	UA72017C2 (de)
WO (1)	WO2001049684A1 (de)
ZA (1)	ZA200205223B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA72934C2 (uk) *	1999-10-22	2005-05-16	Санофі-Авантіс	Феніл- і піридилтетрагідропіридини, що інгібують фактор некрозу пухлин, спосіб їх одержання та фармацевтична композиція
FR2831166B1 (fr) *	2001-10-18	2004-02-27	Sanofi Synthelabo	Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant
FR2832405B1 (fr) *	2001-11-19	2004-12-10	Sanofi Synthelabo	Tetrahydropyridyl-alkyl-heterocycles azotes, procede pour leur preparation et compositions pharmaceutiques les contenant
UA77526C2 (en)	2002-06-07	2006-12-15	Sanofi Aventis	Substituted derivatives of 1-piperazineacylpiperidine, a method for the preparation thereof and their use in therapy
FR2862967B1 (fr) *	2003-12-01	2006-08-04	Sanofi Synthelabo	Derives de (4-phenylpiperazin-1-yl)acylpiperidine, leur preparation et leur application en therapeutique
FR2862968B1 (fr) *	2003-12-01	2006-08-04	Sanofi Synthelabo	Derives de 4-[(arylmethyl)aminomethyl]piperidine, leur preparation et leur application en therapeutique
DK2137162T3 (en) *	2007-03-15	2018-11-26	Novartis Ag	Organic compounds and their applications
US20100041663A1 (en) *	2008-07-18	2010-02-18	Novartis Ag	Organic Compounds as Smo Inhibitors
FR2953836B1 (fr) *	2009-12-14	2012-03-16	Sanofi Aventis	Nouveaux derives (heterocycle-tetrahydro-pyridine)-(piperazinyl)-1-alcanone et (heterocycle-dihydro-pyrrolidine)-(piperazinyl)-1-alcanone et leur utilisation comme inhibiteurs de p75
US11129746B2 (en)	2010-06-23	2021-09-28	Dental Choice Holdings Llc	Method and oral appliance for improving air intake and reducing bruxism
EP2606894A1 (de)	2011-12-20	2013-06-26	Sanofi	Neuartige therapeutische Verwendung von p75-Rezeptorantagonisten
US11795148B2 (en)	2017-12-12	2023-10-24	Queen's University At Kingston	Compounds and methods for inhibiting CYP26 enzymes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2060816C3 (de) *	1970-12-10	1980-09-04	Merck Patent Gmbh, 6100 Darmstadt	4-Phenylpiperidinderivate Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen enthaltend diese Verbindungen
US5273977A (en) *	1990-11-05	1993-12-28	Warner-Lambert Company	Substituted tetrahydropyridines and hydroxypiperidines as central nervous system agents
PT100441A (pt) *	1991-05-02	1993-09-30	Smithkline Beecham Corp	Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
FR2736053B1 (fr) *	1995-06-28	1997-09-19	Sanofi Sa	Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines
GB9604036D0 (en) *	1996-02-26	1996-04-24	Merck Sharp & Dohme	Therapeutic agents
FR2751645B1 (fr) *	1996-07-29	1998-12-24	Sanofi Sa	Amines pour la fabrication de medicaments destines a empecher la proliferation de cellules tumorales
DE19826841A1 (de) *	1998-06-16	1999-12-23	Merck Patent Gmbh	Arylalkanoylpyridazine

2000
- 2000-01-06 FR FR0000113A patent/FR2803593B1/fr not_active Expired - Fee Related
- 2000-12-29 CA CA002395969A patent/CA2395969C/en not_active Expired - Fee Related
- 2000-12-29 MX MXPA02006709A patent/MXPA02006709A/es active IP Right Grant
- 2000-12-29 CZ CZ20022302A patent/CZ300658B6/cs not_active IP Right Cessation
- 2000-12-29 EA EA200200611A patent/EA004858B1/ru not_active IP Right Cessation
- 2000-12-29 SK SK962-2002A patent/SK285557B6/sk not_active IP Right Cessation
- 2000-12-29 JP JP2001550224A patent/JP2004501861A/ja active Pending
- 2000-12-29 AU AU30311/01A patent/AU782650B2/en not_active Ceased
- 2000-12-29 NZ NZ519723A patent/NZ519723A/en not_active IP Right Cessation
- 2000-12-29 IL IL15060500A patent/IL150605A0/xx not_active IP Right Cessation
- 2000-12-29 DE DE60020885T patent/DE60020885T2/de not_active Expired - Lifetime
- 2000-12-29 HU HU0204394A patent/HU224815B1/hu not_active IP Right Cessation
- 2000-12-29 UA UA2002065297A patent/UA72017C2/uk unknown
- 2000-12-29 CN CNB008187592A patent/CN1200939C/zh not_active Expired - Fee Related
- 2000-12-29 RS YUP-513/02A patent/RS50432B/sr unknown
- 2000-12-29 ME MEP-218/08A patent/MEP21808A/xx unknown
- 2000-12-29 US US10/169,528 patent/US6689797B2/en not_active Expired - Fee Related
- 2000-12-29 WO PCT/FR2000/003741 patent/WO2001049684A1/fr active IP Right Grant
- 2000-12-29 EE EEP200200382A patent/EE04814B1/xx not_active IP Right Cessation
- 2000-12-29 KR KR1020027008638A patent/KR100755103B1/ko not_active IP Right Cessation
- 2000-12-29 PL PL357082A patent/PL202761B1/pl not_active IP Right Cessation
- 2000-12-29 BR BR0016921-8A patent/BR0016921A/pt not_active IP Right Cessation
- 2000-12-29 AT AT00990851T patent/ATE297918T1/de not_active IP Right Cessation
- 2000-12-29 EP EP00990851A patent/EP1248785B1/de not_active Expired - Lifetime
2002
- 2002-06-28 ZA ZA200205223A patent/ZA200205223B/en unknown
- 2002-06-28 IS IS6452A patent/IS2472B/is unknown
- 2002-07-04 NO NO20023251A patent/NO322598B1/no not_active IP Right Cessation
2003
- 2003-04-15 HK HK03102738A patent/HK1050532A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUP0204394A2 (en)	2003-05-28
CN1200939C (zh)	2005-05-11
US6689797B2 (en)	2004-02-10
HUP0204394A3 (en)	2005-04-28
SK9622002A3 (en)	2003-03-04
UA72017C2 (en)	2005-01-17
EA004858B1 (ru)	2004-08-26
CA2395969C (en)	2009-05-19
DE60020885T2 (de)	2006-05-11
NO322598B1 (no)	2006-10-30
CZ20022302A3 (cs)	2002-10-16
EE04814B1 (et)	2007-04-16
JP2004501861A (ja)	2004-01-22
EA200200611A1 (ru)	2002-12-26
PL357082A1 (en)	2004-07-12
PL202761B1 (pl)	2009-07-31
MEP21808A (en)	2010-06-10
IS2472B (is)	2008-12-15
HU224815B1 (en)	2006-02-28
EP1248785B1 (de)	2005-06-15
EP1248785A1 (de)	2002-10-16
KR20020063291A (ko)	2002-08-01
CN1433412A (zh)	2003-07-30
CA2395969A1 (en)	2002-07-03
DE60020885D1 (de)	2005-07-21
ZA200205223B (en)	2004-01-26
WO2001049684A1 (fr)	2001-07-12
AU3031101A (en)	2001-07-16
HK1050532A1 (en)	2003-06-27
RS50432B (sr)	2009-12-31
NZ519723A (en)	2005-08-26
KR100755103B1 (ko)	2007-09-04
FR2803593B1 (fr)	2002-02-15
NO20023251L (no)	2002-09-06
ATE297918T1 (de)	2005-07-15
MXPA02006709A (es)	2002-10-23
AU782650B2 (en)	2005-08-18
FR2803593A1 (fr)	2001-07-13
NO20023251D0 (no)	2002-07-04
IS6452A (is)	2002-06-28
US20030083347A1 (en)	2003-05-01
EE200200382A (et)	2003-12-15
YU51302A (sh)	2005-06-10
IL150605A0 (en)	2003-02-12
BR0016921A (pt)	2002-10-15
CZ300658B6 (cs)	2009-07-08

Publication	Publication Date	Title
SK285557B6 (sk)	2007-03-01	Tetrahydropyridíny, spôsob ich prípravy, farmaceutické kompozície obsahujúce tieto tetrahydropyridíny a ich použitie
IL160820A (en)	2009-06-15	Aralkyl-tetrahydro-pyridines, their preparation and pharmaceutical compositions containing same
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